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HOXB2 Antibody (PA5-120690) in WB
Western blot analysis of HOXB2 in mouse kidney. Samples were incubated with HOXB2 Polyclonal antibody (Product # PA5-120690) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-120690
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 50-140 of human HOXB2 (NP_002136.1).
Conjugate
Form
Liquid
Concentration
0.67 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914262
Product Specific Information
Positive test controls include: Mouse kidney.
Immunogen sequence: EQTFPSLQPG ASTLQRPRSQ KRAEDGPALP PPPPPPLPAA PPAPEFPWMK EKKSAKKPSQ SATSPSPAAS AVPASGVGSP ADGLGLPEAG G
Target Information
Hoxb-1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the sonic hedgehog and Mash1 signaling pathways. Hoxb2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. Hoxb2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, Hoxb2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box B2; homeo box B2-like; homeobox B2; Homeobox protein Hox-2.8; Homeobox protein Hox-B2; Hoxb2-like epididymal protein
Gene Aliases: AI894218; Hox-2.8; Hoxb2; Hoxbes2
UniProt ID: (Mouse) P0C1T1
Entrez Gene ID: (Mouse) 103889, (Rat) 100361765
morphogenesis of an epithelial sheet
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
anterior/posterior pattern specification
dorsal/ventral pattern formation
rhombomere 3 development
rhombomere 4 development
facial nerve structural organization
embryonic skeletal system morphogenesis
skeletal system morphogenesis
neural nucleus development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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