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Proteintech
HOXB7 Polyclonal Antibody
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Product Details
12613-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HOXB7 Fusion Protein Ag3245 (1-217 aa encoded by BC015345)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSSLYYANA LFSKYPASSS VFATGAFPEQ TSCAFASNPQ RPGYGAGSGA SFAASMQGLY PGGGGMAGQS AAGVYAAGYG LEPSSFNMHC APFEQNLSGV CPGDSAKAAG AKEQRDSDLA AESNFRIYPW MRSSGTDRKR GRQTYTRYQT LELEKEFHYN RYLTRRRRIE IAHTLCLTER QIKIWFQNRR MKWKKENKTA GPGTTGQDRA EAEEEEEE (1-217 aa encoded by BC015345)
Target Information
The homeobox genes encode transcription factors that regulate developmental processes such as body patterning and organogenesis. The mammalian HOX gene complex consists of 39 genes that are located on 4 linkage groups (clusters), dispersed over 4 chromosomes (HOXA, HOXB, HOXC and HOXD). HOXB7 is expressed in most malignant T-cell lines and CD4-positive peripheral blood cells, and is constitutively expressed in both melanoma primary lesions and cell lines. HOXB7 binds to and transactivates bFGF in melanoma cell lines but SkBr3 breast adenocarcinoma is negative for the expression of both HOXB7 and bFGF genes. HOXB7 may be a key activator of tumor-associated neoangiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: homeo box 2C; homeo box B7; homeo box c1 protein; homeobox gene B7; Homeobox protein HHO.C1; Homeobox protein Hox-2.3; Homeobox protein Hox-2C; Homeobox protein Hox-B7; Homeobox protein MH-22B; Homeobox protein MuB1; Homeobox protein R1B; Hox-23
Gene Aliases: AI325018; HHO.C1; Hox-2.3; HOX2; HOX2C; Hox2r1b; Hoxb-7; HOXB7; R1b
UniProt ID: (Human) P09629, (Rat) P18864, (Mouse) P09024
Entrez Gene ID: (Human) 3217, (Rat) 497985, (Mouse) 15415
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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