Proteintech

HPS4 Polyclonal Antibody

HPS4 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

HPS4 Antibody (14627-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using HPS4 antibody 14627-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

HPS4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HPS4 Antibody in Immunoprecipitation (IP)

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Product Details

14627-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200-1:1,000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HPS4 Fusion Protein Ag6202 (1-350 aa encoded by BC065030)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MATSTSTEA KSASWWNYFF LYDGSKVKEE GDPTRAGICY FYPSQTLLDQ QELLCGQIAG VVRCVSDISD SPPTLVRLRK LKFAIKVDGD YLWVLGCAVE LPDVSCKRFL DQLVGFFNFY NGPVSLAYEN CSQEELSTEW DTFIEQILKN TSDLHKIFNS LWNLDQTKVE PLLLLKAARI LQTCQRSPHI LAGCILYKGL IVSTQLPPSL TAKVLLHRTA PQEQRLPTGE DAPQEHGAAL PPNVQIIPVF VTKEEAISLH EFPVEQMTRS LASPAGLQDG SAQHHPKGGS TSALKENATG HVESMAWTTP DPTSPDEACP DGRKENGCLS GHDLESIRPA GLHNSARGEV L (1-350 aa encoded by BC065030)

Target Information

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 4 (CLIC4) protein, encoded by the CLIC4 gene, is a member of the p64 family; the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Intron retention is a stress response in sensor genes and is restored by Japanese herbal medicines: A basis for future clinical applications.

Gene

Vu TD,Ito N,Oshima K,Maruko A,Nishi A,Mizoguchi K,Odaguchi H,Kobayashi Y,Okada N

Fri Jul 01 00:00:00 UTC 2022

Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes.

American journal of respiratory cell and molecular biology

Kook S,Qi A,Wang P,Meng S,Gulleman P,Young LR,Guttentag SH

Tue May 01 00:00:00 UTC 2018

Gene-edited MLE-15 Cells as a Model for the Hermansky-Pudlak Syndromes.

American journal of respiratory cell and molecular biology

Kook S,Qi A,Wang P,Meng S,Gulleman P,Young LR,Guttentag SH

Tue May 01 00:00:00 UTC 2018

Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5.

PloS one

Stephen J,Yokoyama T,Tolman NJ,O'Brien KJ,Nicoli ER,Brooks BP,Huryn L,Titus SA,Adams DR,Chen D,Gahl WA,Gochuico BR,Malicdan MC

Thu Sep 07 00:00:00 UTC 2017

Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5.

PloS one

Stephen J,Yokoyama T,Tolman NJ,O'Brien KJ,Nicoli ER,Brooks BP,Huryn L,Titus SA,Adams DR,Chen D,Gahl WA,Gochuico BR,Malicdan MC

Thu Sep 07 00:00:00 UTC 2017

In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer.

Molecular genetics and metabolism

Ikawa Y,Hess R,Dorward H,Cullinane AR,Huizing M,Gochuico BR,Gahl WA,Candotti F

Thu Jan 01 00:00:00 UTC 2015

In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer.

Molecular genetics and metabolism

Ikawa Y,Hess R,Dorward H,Cullinane AR,Huizing M,Gochuico BR,Gahl WA,Candotti F

Thu Jan 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: BLOC-3 complex member HPS4; Hermansky-Pudlak syndrome 4; Hermansky-Pudlak syndrome 4 protein; Light-ear protein homolog

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Gene Aliases: BLOC3S2; HPS4; KIAA1667; LE

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UniProt ID: (Human) Q9NQG7

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Entrez Gene ID: (Human) 89781

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Function(s)

protein binding protein homodimerization activity protein dimerization activity

Process(es)

protein targeting lysosome organization blood coagulation hemostasis melanocyte differentiation positive regulation of eye pigmentation protein stabilization positive regulation of protein targeting to mitochondrion

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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HPS4 Polyclonal Antibody

HPS4 Antibody (14627-1-AP) in ICC/IF

Product Details

14627-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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