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Invitrogen
HPS5 Polyclonal Antibody
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FIGURE: 1 / 1
HPS5 Antibody (PA5-88334) in WB
Western blot analysis of HPS5 in extracts of various cell lines. Samples were incubated with HPS5 Polyclonal antibody (Product # PA5-88334) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-88334
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 340-600 of human HPS5 (NP_0091473)
Conjugate
Form
Liquid
Concentration
0.54 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2804838
Product Specific Information
Immunogen sequence: IISSRRGSQS DEDSCSLHSQ TLSEDERFKE FTSQQEEDLP DQCCGSHGNE DNVSHAPVMF ETDKNETFLP FGIPLPFRSP SPLVSLQAVK ESVSSFVRKT TEKIGTLHTS PDLKVRPELR GDEQSCEEDV SSDTCPKEED TEEEKEVTSP PPEEDRFQEL KVATAEAMTK LQDPLVLFES ESLRMVLQEW LSHLEKTFAM KDFSGVSDTD NSSMKLNQDV LLVNESKKGI LDEDNEKEKR DSLGNEESVD KTACECVRSP R; Positive Samples: Jurkat, 293T, B cells; Cellular Location: Cytoplasm, cytosol
Target Information
May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha integrin binding protein 63; Alpha-integrin-binding protein 63; BLOC-2 complex member HPS5; Hermansky-Pudlak syndrome 5 protein; Ru2; Ruby-eye protein 2 homolog
Gene Aliases: AIBP63; BLOC2S2; HPS5; KIAA1017
UniProt ID: (Human) Q9UPZ3
Entrez Gene ID: (Human) 11234
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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