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Invitrogen
HRC Polyclonal Antibody
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Product Details
PA5-52120
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HRC. Recombinant protein control fragment (Product #RP-102410).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642540
Product Specific Information
Immunogen sequence: SHEEDDNDDD DVSTEYGHQA HRHQDHRKEE VEAVSGEHHH HVPDHRHQGH RDEEEDEDVS TERWHQGPQH VHHGLVDEEE EEEEITVQFG HYVASHQPRG HKSDEEDFQD EYKTEVPHHH HHRVPREEDE EVSAELG
Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 51%.
Target Information
May play a role in the regulation of calcium sequestration or release in the SR of skeletal and cardiac muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sarcoplasmic reticulum histidine-rich calcium-binding protein
Gene Aliases: HCP; HRC
UniProt ID: (Human) P23327
Entrez Gene ID: (Human) 3270
regulation of heart rate
muscle contraction
positive regulation of heart rate
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
regulation of peptidyl-serine phosphorylation
positive regulation of heart contraction
regulation of cytosolic calcium ion concentration
negative regulation of cytosolic calcium ion concentration
regulation of ryanodine-sensitive calcium-release channel activity
regulation of cell communication by electrical coupling involved in cardiac conduction
positive regulation of relaxation of cardiac muscle
regulation of calcium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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