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Product Details
H00051144-M08
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
4G11
Immunogen
HSD17B12 (NP_057226, 203 a.a. approximately 271 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: SATKTFVDFF SQCLHEEYRS KGVFVQSVLP YFVATKLAKI RKPTLDKPSP ETFVKSAIKT VGLQSRTNG
Target Information
The enzyme 17-beta hydroxysteroid dehydrogenase-12 (HSD17B12) uses NADPH to reduce 3-ketoacyl-CoA to 3-hydroxyacyl-CoA during the second step of fatty acid elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 17-beta-HSD 12; 17-beta-hydroxysteroid dehydrogenase 12; 17beta-HSD type 12; 3-ketoacyl-CoA reductase; Estradiol 17-beta-dehydrogenase 12; hydroxysteroid (17-beta) dehydrogenase 12; KAR; keratoadhesin; keratonectin; KIK-I; Short chain dehydrogenase/reductase family 12C member 1; short chain dehydrogenase/reductase family 12C, member 1; smooth muscle-specific 17 beta-hydroxysteroid dehydrogenase type 3; steroid dehydrogenase; steroid dehydrogenase homolog; Very-long-chain 3-oxoacyl-CoA reductase
Gene Aliases: 2610510O05Rik; AI172963; HSD17B12; KAR; KIK-I; Kik1; SDR12C1
UniProt ID: (Human) Q53GQ0, (Rat) Q6P7R8, (Mouse) O70503
Entrez Gene ID: (Human) 51144, (Rat) 84013, (Mouse) 56348
fibronectin binding
estradiol 17-beta-dehydrogenase activity
protein binding
collagen binding
heparin binding
long-chain-3-hydroxyacyl-CoA dehydrogenase activity
3-oxo-arachidoyl-CoA reductase activity
3-oxo-behenoyl-CoA reductase activity
3-oxo-lignoceroyl-CoA reductase activity
molecular_function
oxidoreductase activity
fatty acid biosynthetic process
estrogen biosynthetic process
biological_process
positive regulation of cell-substrate adhesion
extracellular matrix organization
oxidation-reduction process
lipid metabolic process
steroid biosynthetic process
metabolic process
long-chain fatty-acyl-CoA biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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