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Product Details
PA5-61173
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HSPA14. Recombinant protein control fragment (Product #RP-97199).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642576
Product Specific Information
Immunogen sequence: FTVLFPSGTP LPARRQHTLQ APGSISSVCL ELYESDGKNS AKEETKFAQV VLQDLDKKEN GLRDILAVLT MKRDGSLHVT CTDQETGKCE AIS
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 96%.
Target Information
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent poly-peptide chains across cellular membranes and the regulation of protein folding. HSPA14 (heat shock 70kDa protein 14), also known as HSP70-4 or HSP70L1, is a 509 amino acid novel HSP protein derived from human dendritic cells. Belonging to the heat shock protein 70 family, HSPA14 is thought to promote dendritic cell maturation. It is also suggested that HSPA14 stimulates secretion of the proinflammatory cytokines interleukin 12p70 (IL-12p70), IL-1 beta, TNF alpha, and the chemokines IP-10, MIP-1 alpha, MIP-1 beta and normal T cell expressed and secreted (RANTES).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Heat shock 70 kDa protein 14; heat shock 70kDa protein 14 isoform 1 variant 3; Heat shock protein; Heat shock protein family A member 14; Heat shock protein HSP60; heat shock protein hsp70-related protein; HSP; HSP70-like protein 1; HSP7E
Gene Aliases: HSP60; HSP70-4; HSP70L1; HSPA14
UniProt ID: (Human) Q0VDF9
Entrez Gene ID: (Human) 51182
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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