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Proteintech
HSPA2 Monoclonal Antibody (1A4A9)
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Product Details
66291-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1A4A9
Immunogen
HSPA2 Fusion Protein Ag24228 (290-639 aa encoded by BC036107)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody well recognized the endogenous HSPA4 protein in testis and multiple cell lines.
Immunogen sequence: LYEGVDFYT SITRARFEEL NADLFRGTLE PVEKALRDAK LDKGQIQEIV LVGGSTRIPK IQKLLQDFFN GKELNKSINP DEAVAYGAAV QAAILIGDKS ENVQDLLLLD VTPLSLGIET AGGVMTPLIK RNTTIPTKQT QTFTTYSDNQ SSVLVQVYEG ERAMTKDNNL LGKFDLTGIP PAPRGVPQIE VTFDIDANGI LNVTAADKST GKENKITITN DKGRLSKDDI DRMVQEAERY KSEDEANRDR VAAKNALESY TYNIKQTVED EKLRGKISEQ DKNKILDKCQ EVINWLDRNQ MAEKDEYEHK QKELERVCNP IISKLYQGGP GGGSGGGGSG ASGGPTIEEV D (290-639 aa encoded by BC036107)
Target Information
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Heat shock 70 kDa protein 2; heat shock 70kD protein 2; heat shock 70kDa protein 2; Heat shock protein; Heat shock protein 70.2; heat shock protein alpha 2; Heat shock protein family A member 2; heat shock protein, 70 kDa 2; Heat shock-related 70 kDa protein 2; HSP; HST; Testis-specific heat shock protein-related; testis-specific heat shock protein-related gene hst70
Gene Aliases: 70kDa; Hcp70.2; HSP70-2; HSP70-3; HSP70.2; HSP70A2; HSPA2; Hspt70; Hst70
UniProt ID: (Human) P54652, (Rat) P14659, (Mouse) P17156
Entrez Gene ID: (Human) 3306, (Rat) 60460, (Mouse) 15512
response to unfolded protein
male meiosis
male meiosis I
spermatogenesis
spermatid development
response to heat
response to cold
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle
protein refolding
synaptonemal complex disassembly
negative regulation of inclusion body assembly
positive regulation of calcium-transporting ATPase activity
positive regulation of protein phosphorylation
multicellular organism development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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