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Proteintech
HSPH1 Monoclonal Antibody (3H5A5)
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Product Details
66723-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3H5A5
Immunogen
HSPH1 Fusion Protein Ag27521 (508-858 aa encoded by BC037553)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Western blot analysis using this antibody detected a band around 110 kDa in various lysates.
Immunogen sequence: MSSEADMEC LNQRPPENPD TDKNVQQDNS EAGTQPQVQT DAQQTSQSPP SPELTSEENK IPDADKANEK KVDQPPEAKK PKIKVVNVEL PIEANLVWQL GKDLLNMYIE TEGKMIMQDK LEKERNDAKN AVEEYVYEFR DKLCGPYEKF ICEQDHQNFL RLLTETEDWL YEEGEDQAKQ AYVDKLEELM KIGTPVKVRF QEAEERPKMF EELGQRLQHY AKIAADFRNK DEKYNHIDES EMKKVEKSVN EVMEWMNNVM NAQAKKSLDQ DPVVRAQEIK TKIKELNNTC EPVVTQPKPK IESPKLERTP NGPNIDKKEE DLEDKNNFGA EPPHQNGECY PNEKNSVNMD LD (508-858 aa encoded by BC037553)
Target Information
HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 42 degrees C-HSP; Antigen NY-CO-25; heat shock 105kD alpha; heat shock 105kD beta; heat shock 105kDa/110kDa protein 1; Heat shock 110 kDa protein; Heat shock protein; Heat shock protein 105 kDa; heat shock protein 110; Heat shock protein family H member 1; heat shock protein, 105 kDa; Heat shock-related 100 kDa protein E7I; HSP; HSP-E7I; HSP105 42 C-HSP; NY CO 25
Gene Aliases: 105kDa; AI790491; hsp-E7I; HSP105; HSP105A; HSP105B; HSP110; hsp110/105; HSPH1; KIAA0201; NY-CO-25
UniProt ID: (Human) Q92598, (Mouse) Q61699
Entrez Gene ID: (Human) 10808, (Mouse) 15505
response to unfolded protein
negative regulation of neuron apoptotic process
positive regulation of MHC class I biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
chaperone mediated protein folding requiring cofactor
positive regulation of NK T cell activation
positive regulation of protein tyrosine kinase activity
regulation of microtubule cytoskeleton organization
negative regulation of establishment of protein localization to mitochondrion
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
negative regulation of p38MAPK cascade
negative regulation of apoptotic signaling pathway
receptor-mediated endocytosis
regulation of cellular response to heat
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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