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Invitrogen
HTR1A Polyclonal Antibody
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HTR1A Antibody (PA5-49346) in WB
Western blot analysis of HTR1A in lysate from human brain tissue. Samples were incubated with HTR1A polyclonal antibody (Product # PA5-49346) using a dilution of 1:1,000 followed by goat anti-rabbit IgG H&L (HRP) at a dilution of 1:5,000. Lysate at 35 µg.
Product Details
PA5-49346
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 239-273 amino acids from the Central region of human HTR1A.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2634800
Target Information
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-HT-1A; 5-HT1a receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5-hydroxytryptamine receptor 1A; G-21; guanine nucleotide-binding regulatory protein-coupled receptor; Serotonin receptor 1A
Gene Aliases: 5-HT-1A; 5-HT1A; 5HT1a; ADRB2RL1; ADRBRL1; G-21; HTR1A; PFMCD
UniProt ID: (Human) P08908
Entrez Gene ID: (Human) 3350
behavioral fear response
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
serotonin receptor signaling pathway
cell proliferation
positive regulation of cell proliferation
regulation of serotonin secretion
exploration behavior
regulation of dopamine metabolic process
vasoconstriction
serotonin metabolic process
regulation of hormone secretion
regulation of behavior
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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