Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
HTR1A Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 6
HTR1A Antibody (PA5-95035) in IHC (P)
Immunohistochemistry (Paraffin) analysis of HTR1A in paraffin-embedded section of human endometrial adenocarcinoma tissue using HTR1A Polyclonal Antibody (Product # PA5-95035). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilut... View More
Product Details
PA5-95035
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor (404-422aa NKDFQNAFKKIIKCKFCRQ).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2806841
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human hepatocellular carcinoma tumor tissue (HCCT), rat liver tissue. IHC: human endometrial adenocarcinoma tissue, human lung cancer tissue, rat lymphaden tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 5-HT-1A; 5-HT1A; 5-HT1a receptor; 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled; 5-hydroxytryptamine receptor 1A; G-21; guanine nucleotide-binding regulatory protein-coupled receptor; Serotonin receptor 1A
Gene Aliases: 5-HT-1A; 5-HT1A; 5HT1A; ADRB2RL1; ADRBRL1; G-21; HTR1A; PFMCD; RAT5HT1A
UniProt ID: (Human) P08908, (Rat) P19327
Entrez Gene ID: (Human) 3350, (Rat) 24473
behavioral fear response
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
serotonin receptor signaling pathway
cell proliferation
positive regulation of cell proliferation
regulation of serotonin secretion
exploration behavior
regulation of dopamine metabolic process
vasoconstriction
serotonin metabolic process
regulation of hormone secretion
regulation of behavior
positive regulation of microtubule depolymerization
regulation of feeding behavior
NMDA glutamate receptor clustering
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support