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Product Details
PA5-33297
Product Specifications
Species Reactivity
Bat,
Bovine,
Horse,
Guinea pig,
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human 5HT1E Receptor.
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2550681
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Elephant, Bovine, Bat, Horse, Guinea pig (100%).
Target Information
G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-HT-1E; 5-HT1E; 5-HT1e receptor; 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled; 5-hydroxytryptamine receptor 1E; 5HT1E Receptor; HT1e receptor; S31; Serotonin receptor 1E
Gene Aliases: 5-HT1E; 5HT1E; BOS_9752; HTR1E
UniProt ID: (Human) P28566, (Guinea pig) Q6VB83
Entrez Gene ID: (Human) 3354, (Bovine) 616356, (Guinea pig) 100379275
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
serotonin receptor signaling pathway
chemical synaptic transmission
negative regulation of cAMP metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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