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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • HTR3A Antibodies

          Invitrogen

          HTR3A Monoclonal Antibody (4D5E7)

          View all (23) HTR3A antibodies

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          Datasheet
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          Datasheet
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          Cite HTR3A Monoclonal Antibody (4D5E7)

          • Antibody Testing Data (6)
          HTR3A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          HTR3A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 6

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          HTR3A Antibody (MA5-31771) in ICC/IF

          Immunocytochemistry analysis of HTR3A in Hela cells (green). Sample was incubated with HTR3A monoclonal antibody (Product # MA5-31771) using a dilution of 1:100-1:500 followed by DRAQ5 fluorescent DNA dye (blue), and Alexa Fluor- 555 phalloidin (red labeled actin filaments) . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HTR3A Antibody in Immunocytochemistry (ICC/IF)
          HTR3A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HTR3A Antibody in Western Blot (WB)
          HTR3A Antibody in Western Blot (WB)
          HTR3A Antibody in Flow Cytometry (Flow)
          HTR3A Antibody in ELISA (ELISA)

          Product Details

          MA5-31771

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:1,000
          -

          Immunocytochemistry (ICC/IF)

          1:100-1:500
          -

          Flow Cytometry (Flow)

          1:200-1:400
          -

          ELISA (ELISA)

          1:10,000
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          4D5E7

          Immunogen

          Purified recombinant fragment of human HTR3A (AA: extra 24-157) expressed in E. coli.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS

          Contains

          0.05% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2787394

          Product Specific Information

          MA5-31771 has been tested in indirect ELISA.

          Target Information

          The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 5-HT-3; 5-HT3-A; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; 5-hydroxytryptamine receptor 3; 5-hydroxytryptamine receptor 3A; 5HT3 serotonin receptor; serotonin receptor; Serotonin receptor 3A; Serotonin-gated ion channel receptor; truncated receptor

          View more View less

          Gene Aliases: 5-HT-3; 5-HT3A; 5-HT3R; 5HT3R; HTR3; HTR3A

          View more View less

          UniProt ID: (Human) P46098

          View more View less

          Entrez Gene ID: (Human) 3359

          View more View less

          Function(s)
          acetylcholine-activated cation-selective channel activity serotonin-activated cation-selective channel activity voltage-gated potassium channel activity protein binding acetylcholine receptor activity serotonin-gated cation channel activity acetylcholine binding serotonin binding
          Process(es)
          signal transduction synaptic transmission, cholinergic ion transmembrane transport response to cocaine response to ethanol cellular response to growth factor stimulus potassium ion transmembrane transport
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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