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Proteintech
HTR4 Polyclonal Antibody
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Product Details
21165-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HTR4 Fusion Protein Ag15226 (301-388 aa encoded by BC074755)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GYINSGLNP FLYAFLNKSF RRAFLIILCC DDERYRRPSI LGQTVPCSTT TINGSTHVLR DAVECGGQWE SQCHPPATSP LVAAQPSDT (301-388 aa encoded by BC074755)
Target Information
This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described, but the full-length nature of some transcript variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5-HT-4; 5-HT4 receptor; 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled; 5-hydroxytryptamine receptor 4; 5HT4; 5HT4 receptor; cardiac 5-HT4 receptor; Serotonin receptor 4
Gene Aliases: 5-HT-4; 5-HT4; 5-HT4R; 5-HT<4L>; 5HTR4; HTR4
UniProt ID: (Human) Q13639, (Mouse) P97288
Entrez Gene ID: (Human) 3360, (Mouse) 15562
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
serotonin receptor signaling pathway
gamma-aminobutyric acid signaling pathway
chemical synaptic transmission
regulation of appetite
signal transduction
adenylate cyclase-activating G-protein coupled receptor signaling pathway
sensory perception of chemical stimulus
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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