Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
HTR6 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-33854
Product Specifications
Species Reactivity
Dog,
Horse,
Hamster,
Human,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 17 amino acid peptide from C-terminus of human HTR6 / 5-HT6.
Conjugate
Form
Liquid
Concentration
0.7 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551223
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Rat, Hamster, Panda, Dog, Horse (100%).
Target Information
This is one of the several different receptors for 5-hydroxytryptamine, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. It has a high affinity for tricyclic psychotropic drugs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 5-HT-6; 5-HT6; 5-HT6 receptor; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; 5-hydroxytryptamine receptor 6; Serotonin receptor 6; ST-B17
Gene Aliases: 5-HT6; 5-HT6R; HTR6; I79_014435
UniProt ID: (Human) P50406
Entrez Gene ID: (Human) 3362, (Dog) 487402, (Chinese hamster) 100752934, (Rat) 64354
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
serotonin receptor signaling pathway
chemical synaptic transmission
cerebral cortex cell migration
positive regulation of TOR signaling
brain development
learning
negative regulation of glutamate secretion
negative regulation of gamma-aminobutyric acid secretion
positive regulation of gamma-aminobutyric acid secretion
negative regulation of acetylcholine secretion, neurotransmission
response to estradiol
positive regulation of dopamine secretion
response to drug
long-term synaptic potentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support