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Invitrogen
HUS1 Polyclonal Antibody
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FIGURE: 1 / 5
HUS1 Antibody (PA5-109839) in IHC (P)
Immunohistochemistry analysis of HUS1 in paraffin-embedded human uterine cancer. Samples were incubated with HUS1 Polyclonal antibody (Product # PA5-109839) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-109839
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human HUS1 (NP_004498.1).
Conjugate
Form
Liquid
Concentration
1.31 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855250
Product Specific Information
Immunogen sequence: MKFRAKIVDG ACLNHFTRIS NMIAKLAKTC TLRISPDKLN FILCDKLANG GVSMWCELEQ ENFFNEFQME GVSAENNEIY LELTSENLSR ALKTAQNARA LKIKLTNKHF PCLTVSVELL SMSSSSRIVT HDIPIKVIPR KLWKDLQEPV VPDPDVSIYL PVLKTMKSVV EKMKNISNHL VIEANLDGEL NLKIETELVC VTTHFKDLGN PPLASESTHE DRNVEHMAEV HIDIRKLLQF LAGQQVNPTK ALCNIVNNKM VHFDLLHEDV SLQYFIPALS
Target Information
The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Checkpoint protein HUS1; hHUS1; HUS1 checkpoint homolog; Hus1 homolog; HUS1 protein; hus1+-like protein; mHUS1
Gene Aliases: hHUS1; HUS1
UniProt ID: (Human) O60921, (Mouse) Q8BQY8
Entrez Gene ID: (Human) 3364, (Rat) 498411, (Mouse) 15574
DNA damage checkpoint
double-strand break repair via homologous recombination
regulation of protein phosphorylation
DNA replication
DNA repair
nucleotide-excision repair
protein phosphorylation
cellular response to DNA damage stimulus
negative regulation of DNA replication
response to UV
embryo development
intra-S DNA damage checkpoint
mitotic DNA replication checkpoint
meiotic DNA integrity checkpoint
cellular response to ionizing radiation
regulation of signal transduction by p53 class mediator
mitotic cell cycle checkpoint
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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