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Invitrogen
Hemopexin Recombinant Rabbit Monoclonal Antibody (1M6O3)
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FIGURE: 1 / 6
Hemopexin Antibody (MA5-35760) in IHC (P)
Immunohistochemistry analysis of Hemopexin in paraffin-embedded rat liver. Samples were incubated with Hemopexin Monoclonal antibody (Product # MA5-35760) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Product Details
MA5-35760
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1M6O3
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 363-462 of human Hemopexin (HPX) (P02790)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849660
Product Specific Information
Immunogen sequence: AFICPGSSRL HIMAGRRLWW LDLKSGAQAT WTELPWPHEK VDGALCMEKS LGPNSCSANG PGLYLIHGPN LYCYSDVEKL NAAKALPQPQ NVTSLLGCTH
Target Information
Hemopexin is a serum glycoprotein that binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Structurally, hemopexin consists of two similar halves of approximately two hundred amino acid residues connected by a histidine-rich hinge region. Each half is itself formed by the repetition of a basic unit of some 35 to 45 residues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-1B-glycoprotein; Hemopexin
Gene Aliases: HPX; Hpxn; HX
UniProt ID: (Human) P02790, (Mouse) Q91X72, (Rat) P20059
Entrez Gene ID: (Human) 3263, (Mouse) 15458, (Rat) 58917
positive regulation of immunoglobulin production
positive regulation of humoral immune response mediated by circulating immunoglobulin
transport
hemoglobin metabolic process
heme metabolic process
positive regulation of tyrosine phosphorylation of Stat1 protein
regulation of protein metabolic process
positive regulation of response to interferon-gamma
positive regulation of interferon-gamma-mediated signaling pathway
cellular iron ion homeostasis
receptor-mediated endocytosis
heme transport
viral process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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