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Bioss
Heparanase Polyclonal Antibody
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Heparanase Antibody (BS-1541R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Human Glioma Carcinoma; Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15 minutes; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20 minutes; Antibody incubation with Heparanase Polyclonal Antibody, Unconjugated (bs-1541R) at 1:200 overnight at 4°C, followed by a conjugated seconda... View More
Product Details
BS-1541R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Heparanase 50 kDa subunit, amino acids 141-240.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al. ). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Endo-glucoronidase; endoglycosidase heparanase; Heparanase; Heparanase-1; heparanase-like; Hpa1
Gene Aliases: HEP; HPA; HPA1; HPR1; HPSE; HPSE1; HSE1
UniProt ID: (Human) Q9Y251, (Mouse) Q6YGZ1, (Rat) Q71RP1
Entrez Gene ID: (Human) 10855, (Mouse) 15442, (Rat) 64537
carbohydrate metabolic process
cell adhesion
cell-matrix adhesion
positive regulation of vascular endothelial growth factor production
positive regulation of blood coagulation
heparan sulfate proteoglycan catabolic process
positive regulation of osteoblast proliferation
wound healing
regulation of hair follicle development
positive regulation of hair follicle development
positive regulation of protein kinase B signaling
angiogenesis involved in wound healing
vascular wound healing
glycosaminoglycan catabolic process
proteoglycan metabolic process
extracellular matrix organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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