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Invitrogen
Hippocalcin Polyclonal Antibody
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FIGURE: 1 / 2
Hippocalcin Antibody (PA5-115359) in ICC/IF
Immunocytochemistry analysis of Hippocalcin in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115359) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat... View More
Product Details
PA5-115359
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human HPCA(Accession P84074), corresponding to amino acid residues T74-I124.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2899995
Product Specific Information
Antibody detects endogenous levels of total Hippocalcin.
Target Information
The protein encoded by this gene is a member of neuron-specific calcium-binding proteins family found in the retina and brain. This protein is associated with the plasma membrane. It has similarities to proteins located in the photoreceptor cells that regulate photosignal transduction in a calcium-sensitive manner. This protein displays recoverin activity and a calcium-dependent inhibition of rhodopsin kinase. It is identical to the rat and mouse hippocalcin proteins and thought to play an important role in neurons of the central nervous system in a number of species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium-binding protein; Calcium-binding protein BDR-2; Neuron-specific calcium-binding protein hippocalcin; P23K
Gene Aliases: BDR2; DYT2; HPCA
UniProt ID: (Human) P84074, (Mouse) P84075, (Rat) P84076
Entrez Gene ID: (Human) 3208, (Mouse) 15444, (Rat) 29177
brain development
calcium-mediated signaling
negative regulation of guanylate cyclase activity
activation of phospholipase D activity
positive regulation of adenylate cyclase activity
inner ear development
retina development in camera-type eye
cellular response to electrical stimulus
positive regulation of protein targeting to membrane
response to ketamine
response to L-glutamate
cellular response to monosodium glutamate
response to Aroclor 1254
positive regulation of phospholipase activity
response to organic cyclic compound
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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