Proteintech

His-Tag Monoclonal Antibody (1B7G5), HRP

FIGURE: 1 / 2

His-Tag Antibody (HRP-66005) in WB

Recombinant protein were subjected to SDS PAGE followed by western blot with 6*His, His-Tag antibody (Product # HRP-66005) at dilution of 1:10,000 incubated at room temperature for 1.5 hours.

Product Image Gallery

Product Details

HRP-66005

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:50,000

View 56 publications 56 publications

ELISA (ELISA)

View 3 publications 3 publications

Immunoprecipitation (IP)

View 3 publications 3 publications

Miscellaneous PubMed (MISC)

View 6 publications 6 publications

Not applicable (N/A)

View 41 publications 41 publications

Product Specifications

Species Reactivity

Tag

Published species

Tag

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

1B7G5

Immunogen

6xHis peptide

Conjugate

HRP HRP HRP

Form

Liquid

Concentration

0.4 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.5% BSA

Contains

0.02% thimerosal, 0.05% ProClin 300

Storage conditions

-20°C, store in dark

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

This antibody is conjugated with HRP. Note: Do not add azide (Sodium Azide or Smite) into the dilution buffer. azide is the HRP inhibitor which decreases the enzymatic activity of HRP.

Target Information

The 6x His tag is a synthetic oligo peptide consisting of 6 consecutive histidine residues (HHHHHH). The His tag is commonly expressed as a tag at either N-or C-terminal regions of recombinant proteins to allow isolation or purification by immobilized metal affinity chromatography. Epitope tagging is a technique in which a known epitope is fused to a recombinant protein using genetic engineering. By choosing a particular epitope and recombinant protein combination, epitope tagging makes it possible to detect proteins for which no antibody is available. His epitope tagged proteins that contain a stretch of histidine residues at the carboxyl or amino terminus are used for purification of recombinant proteins by means of metal chelate chromatography due to metal binding properties of histidine clusters on His tagged proteins. For example, the affinity of the histidine-tag motif to Ni2+ by chelation is strong and selective enough to enable purification of the protein to homogeneity by affinity chromatography on a Ni2+-NTA adsorbent. His tag-specific antibodies are used to facilitate detection or coimmunopreciptation of tagged proteins.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion.

Cell death and differentiation

Zhang CX,Ye SB,Ni JJ,Cai TT,Liu YN,Huang DJ,Mai HQ,Chen QY,He J,Zhang XS,Zeng YX,Li J,Cui J

Fri Nov 01 00:00:00 UTC 2019

A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's-associated pathologies.

Journal of neurochemistry

Cline EN,Das A,Bicca MA,Mohammad SN,Schachner LF,Kamel JM,DiNunno N,Weng A,Paschall JD,Bu RL,Khan FM,Rollins MG,Ives AN,Shekhawat G,Nunes-Tavares N,de Mello FG,Compton PD,Kelleher NL,Klein WL

Fri Mar 01 00:00:00 UTC 2019

A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's-associated pathologies.

Journal of neurochemistry

Cline EN,Das A,Bicca MA,Mohammad SN,Schachner LF,Kamel JM,DiNunno N,Weng A,Paschall JD,Bu RL,Khan FM,Rollins MG,Ives AN,Shekhawat G,Nunes-Tavares N,de Mello FG,Compton PD,Kelleher NL,Klein WL

Fri Mar 01 00:00:00 UTC 2019

The retroviral accessory proteins S2, Nef, and glycoMA use similar mechanisms for antagonizing the host restriction factor SERINC5.

The Journal of biological chemistry

Ahmad I,Li S,Li R,Chai Q,Zhang L,Wang B,Yu C,Zheng YH

Fri Apr 26 00:00:00 UTC 2019

Novel Mussel-Inspired Universal Surface Functionalization Strategy: Protein-Based Coating with Residue-Specific Post-Translational Modification in Vivo.

ACS applied materials & interfaces

Qi H,Zheng W,Zhang C,Zhou X,Zhang L

Wed Apr 03 00:00:00 UTC 2019

Characterization of PPIB interaction in the P3H1 ternary complex and implications for its pathological mutations.

Cellular and molecular life sciences : CMLS

Wu J,Zhang W,Xia L,Feng L,Shu Z,Zhang J,Ye W,Zeng N,Zhou A

Tue Oct 01 00:00:00 UTC 2019

Receptor-Mediated Field Effect Transistor Biosensor for Real-Time Monitoring of Glutamate Release from Primary Hippocampal Neurons.

Analytical chemistry

Li YT,Jin X,Tang L,Lv WL,Xiao MM,Zhang ZY,Gao C,Zhang GJ

Tue Jul 02 00:00:00 UTC 2019

Vancomycin does not affect the enzymatic activities of purified VanSA.

PloS one

Upton EC,Maciunas LJ,Loll PJ

Wed Oct 16 00:00:00 UTC 2019

Characterization of two engineered dimeric Zika virus envelope proteins as immunogens for neutralizing antibody selection and vaccine design.

The Journal of biological chemistry

Yang C,Zeng F,Gao X,Zhao S,Li X,Liu S,Li N,Deng C,Zhang B,Gong R

Fri Jul 05 00:00:00 UTC 2019

Identification of a cellularly active SIRT6 allosteric activator.

Nature chemical biology

Huang Z,Zhao J,Deng W,Chen Y,Shang J,Song K,Zhang L,Wang C,Lu S,Yang X,He B,Min J,Hu H,Tan M,Xu J,Zhang Q,Zhong J,Sun X,Mao Z,Lin H,Xiao M,Chin YE,Jiang H,Xu Y,Chen G,Zhang J

Sat Dec 01 00:00:00 UTC 2018

Identification of a cellularly active SIRT6 allosteric activator.

Nature chemical biology

Huang Z,Zhao J,Deng W,Chen Y,Shang J,Song K,Zhang L,Wang C,Lu S,Yang X,He B,Min J,Hu H,Tan M,Xu J,Zhang Q,Zhong J,Sun X,Mao Z,Lin H,Xiao M,Chin YE,Jiang H,Xu Y,Chen G,Zhang J

Sat Dec 01 00:00:00 UTC 2018

Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels.

Molecular neurobiology

Bu W,Liang Q,Zhi L,Maciunas L,Loll PJ,Eckenhoff RG,Covarrubias M

Thu Feb 01 00:00:00 UTC 2018

Sites and Functional Consequence of Alkylphenol Anesthetic Binding to Kv1.2 Channels.

Molecular neurobiology

Bu W,Liang Q,Zhi L,Maciunas L,Loll PJ,Eckenhoff RG,Covarrubias M

Thu Feb 01 00:00:00 UTC 2018

An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.

RNA biology

Xu X,Zhou H,Zhou Q,Hong F,Vo MN,Niu W,Wang Z,Xiong X,Nakamura K,Wakasugi K,Schimmel P,Yang XL

Fri Nov 02 00:00:00 UTC 2018

An alternative conformation of human TrpRS suggests a role of zinc in activating non-enzymatic function.

RNA biology

Xu X,Zhou H,Zhou Q,Hong F,Vo MN,Niu W,Wang Z,Xiong X,Nakamura K,Wakasugi K,Schimmel P,Yang XL

Fri Nov 02 00:00:00 UTC 2018

GlpR Is a Direct Transcriptional Repressor of Fructose Metabolic Genes in Haloferax volcanii.

Journal of bacteriology

Martin JH,Sherwood Rawls K,Chan JC,Hwang S,Martinez-Pastor M,McMillan LJ,Prunetti L,Schmid AK,Maupin-Furlow JA

Sat Sep 01 00:00:00 UTC 2018

GlpR Is a Direct Transcriptional Repressor of Fructose Metabolic Genes in Haloferax volcanii.

Journal of bacteriology

Martin JH,Sherwood Rawls K,Chan JC,Hwang S,Martinez-Pastor M,McMillan LJ,Prunetti L,Schmid AK,Maupin-Furlow JA

Sat Sep 01 00:00:00 UTC 2018

Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit.

Biochemistry

Wang G,Zhang M,Jang H,Lu S,Lin S,Chen G,Nussinov R,Zhang J,Gaponenko V

Tue Mar 27 00:00:00 UTC 2018

High-efficiency production of human serum albumin in the posterior silk glands of transgenic silkworms, Bombyx mori L.

PloS one

Qian Q,You Z,Ye L,Che J,Wang Y,Wang S,Zhong B

Mon Feb 26 00:00:00 UTC 2018

High-efficiency production of human serum albumin in the posterior silk glands of transgenic silkworms, Bombyx mori L.

PloS one

Qian Q,You Z,Ye L,Che J,Wang Y,Wang S,Zhong B

Mon Feb 26 00:00:00 UTC 2018

In vitro Analysis of Ubiquitin-like Protein Modification in Archaea.

Bio-protocol

Fu X,Adams Z,Maupin-Furlow JA

Sun May 20 00:00:00 UTC 2018

In vitro Analysis of Ubiquitin-like Protein Modification in Archaea.

Bio-protocol

Fu X,Adams Z,Maupin-Furlow JA

Sun May 20 00:00:00 UTC 2018

3-Hydroxyisobutyrate Dehydrogenase Is Involved in Both, Valine and Isoleucine Degradation in Arabidopsis thaliana.

Plant physiology

Schertl P,Danne L,Braun HP

Fri Sep 01 00:00:00 UTC 2017

3-Hydroxyisobutyrate Dehydrogenase Is Involved in Both, Valine and Isoleucine Degradation in Arabidopsis thaliana.

Plant physiology

Schertl P,Danne L,Braun HP

Fri Sep 01 00:00:00 UTC 2017

5-Aminolevulinic Acid Dehydratase Gene Dosage Affects Programmed Cell Death and Immunity.

Plant physiology

Chai Q,Shang X,Wu S,Zhu G,Cheng C,Cai C,Wang X,Guo W

Fri Sep 01 00:00:00 UTC 2017

5-Aminolevulinic Acid Dehydratase Gene Dosage Affects Programmed Cell Death and Immunity.

Plant physiology

Chai Q,Shang X,Wu S,Zhu G,Cheng C,Cai C,Wang X,Guo W

Fri Sep 01 00:00:00 UTC 2017

A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers.

Journal of neurochemistry

Sebollela A,Cline EN,Popova I,Luo K,Sun X,Ahn J,Barcelos MA,Bezerra VN,Lyra E Silva NM,Patel J,Pinheiro NR,Qin LA,Kamel JM,Weng A,DiNunno N,Bebenek AM,Velasco PT,Viola KL,Lacor PN,Ferreira ST,Klein WL

Fri Sep 01 00:00:00 UTC 2017

A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers.

Journal of neurochemistry

Fri Sep 01 00:00:00 UTC 2017

Effects of microvirin monomers and oligomers on hepatitis C virus.

Bioscience reports

Min YQ,Duan XC,Zhou YD,Kulinich A,Meng W,Cai ZP,Ma HY,Liu L,Zhang XL,Voglmeir J

Fri Jun 30 00:00:00 UTC 2017

Effects of microvirin monomers and oligomers on hepatitis C virus.

Bioscience reports

Min YQ,Duan XC,Zhou YD,Kulinich A,Meng W,Cai ZP,Ma HY,Liu L,Zhang XL,Voglmeir J

Fri Jun 30 00:00:00 UTC 2017

Construction of an expression vector that uses the aph promoter for protein expression in Corynebacterium glutamicum.

Plasmid

Zhang W,Zhao Z,Yang Y,Liu X,Bai Z

Wed Nov 01 00:00:00 UTC 2017

Construction of an expression vector that uses the aph promoter for protein expression in Corynebacterium glutamicum.

Plasmid

Zhang W,Zhao Z,Yang Y,Liu X,Bai Z

Wed Nov 01 00:00:00 UTC 2017

Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus.

Viruses

Sun Y,Zhang H,Shi J,Zhang Z,Gong R

Thu Sep 14 00:00:00 UTC 2017

Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus.

Viruses

Sun Y,Zhang H,Shi J,Zhang Z,Gong R

Thu Sep 14 00:00:00 UTC 2017

Bioinformatics

Protein Aliases: 6His tag; 6X His; His Tag; Histidine Tag

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His-Tag Monoclonal Antibody (1B7G5), HRP

His-Tag Antibody (HRP-66005) in WB

Product Details

HRP-66005

Western Blot (WB)

ELISA (ELISA)

Immunoprecipitation (IP)

Miscellaneous PubMed (MISC)

Not applicable (N/A)

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