Active Motif

Histone H3K4me3 Polyclonal Antibody

Histone H3K4me3 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 5

Histone H3K4me3 Antibody (39159) in ICC/IF

Histone H3 trimethyl Lys4 antibody tested by immunofluorescence. HeLa cells stained at 1:1,000 with Histone H3 trimethyl Lys4 antibody. Top left: Histone H3 trimethyl Lys4 antibody. Top right: Stained with DAPI. Bottom left: Same cells stained with alpha Tubulin mAb (Clone 5-B-1-2). Bottom right: Merge of all 3 images

Histone H3K4me3 Antibody in Western Blot (WB)

Histone H3K4me3 Antibody in ChIP Assay (ChIP)

Histone H3K4me3 Antibody in ChIP-Sequencing (ChIP-Seq)

Histone H3K4me3 Antibody in Dot Blot (DB)

Product Image Gallery

Product Details

39159

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 11 publications 11 publications

Immunocytochemistry (ICC/IF)

1:500-1:1,000

Flow Cytometry (Flow)

View 1 publication 1 publication

ChIP assay (ChIP)

3-5 µL

View 5 publications 5 publications

ChIP-sequencing (ChIP-Seq)

3 µL

View 13 publications 13 publications

Dot blot (DB)

Assay-dependent

Miscellaneous PubMed (MISC)

View 21 publications 21 publications

Product Specifications

Species Reactivity

Human, Mouse, Yeast

Published species

Chicken, Fungi, Human, Mouse, Non-human primate, Rat, Yeast

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

This Histone H3 trimethyl Lys4 antibody was raised against a peptide including trimethyl-lysine 4 of histone H3.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

whole serum with 30% glycerol

Contains

0.035% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2615077

Target Information

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.

Nature genetics

Dellino GI,Palluzzi F,Chiariello AM,Piccioni R,Bianco S,Furia L,De Conti G,Bouwman BAM,Melloni G,Guido D,Giacò L,Luzi L,Cittaro D,Faretta M,Nicodemi M,Crosetto N,Pelicci PG

Research topic: Cancer, DNA Damage

Sat Jun 01 00:00:00 UTC 2019

Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation.

Cancer cell

Erkek S,Johann PD,Finetti MA,Drosos Y,Chou HC,Zapatka M,Sturm D,Jones DTW,Korshunov A,Rhyzova M,Wolf S,Mallm JP,Beck K,Witt O,Kulozik AE,Frühwald MC,Northcott PA,Korbel JO,Lichter P,Eils R,Gajjar A,Roberts CWM,Williamson D,Hasselblatt M,Chavez L,Pfister SM,Kool M

Research topic: atypical teratoid rhabdoid tumors (ATRT), Gene Regulation

Mon Jan 14 00:00:00 UTC 2019

Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities.

Molecular cell

Scelfo A,Fernández-Pérez D,Tamburri S,Zanotti M,Lavarone E,Soldi M,Bonaldi T,Ferrari KJ,Pasini D

Research topic: Transcription

Thu Jun 06 00:00:00 UTC 2019

RSC-Associated Subnucleosomes Define MNase-Sensitive Promoters in Yeast.

Molecular cell

Brahma S,Henikoff S

Research topic: Chromatin Structure

Thu Jan 17 00:00:00 UTC 2019

LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription.

Oncogene

Peng WX,He RZ,Zhang Z,Yang L,Mo YY

Research topic: Pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC)

Tue Oct 01 00:00:00 UTC 2019

HiPLA: High-throughput imaging proximity ligation assay.

Methods (San Diego, Calif.)

Serebryannyy LA,Misteli T

Research topic: Methods Paper

Fri Mar 15 00:00:00 UTC 2019

Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure.

Alcoholism, clinical and experimental research

Jarmasz JS,Stirton H,Basalah D,Davie JR,Clarren SK,Astley SJ,Del Bigio MR

Research topic: Neurobiology, Alcoholism

Sat Jun 01 00:00:00 UTC 2019

Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure.

Alcoholism, clinical and experimental research

Jarmasz JS,Stirton H,Basalah D,Davie JR,Clarren SK,Astley SJ,Del Bigio MR

Research topic: Neurobiology, Alcoholism

Sat Jun 01 00:00:00 UTC 2019

IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP.

eLife

Roy A,Ghosh A,Kumar B,Chandran B

Research topic: Virology, KSHV

Mon Nov 04 00:00:00 UTC 2019

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Cancer cell

Stewart E,McEvoy J,Wang H,Chen X,Honnell V,Ocarz M,Gordon B,Dapper J,Blankenship K,Yang Y,Li Y,Shaw TI,Cho JH,Wang X,Xu B,Gupta P,Fan Y,Liu Y,Rusch M,Griffiths L,Jeon J,Freeman BB,Clay MR,Pappo A,Easton J,Shurtleff S,Shelat A,Zhou X,Boggs K,Mulder H,Yergeau D,Bahrami A,Mardis ER,Wilson RK,Zhang J,Peng J,Downing JR,Dyer MA

Research topic: Skeletal Muscle - Rhabdomyosarcoma

Mon Sep 10 00:00:00 UTC 2018

Set1 and Kdm5 are antagonists for H3K4 methylation and regulators of the major conidiation-specific transcription factor gene ABA1 in Fusarium fujikuroi.

Environmental microbiology

Janevska S,Güldener U,Sulyok M,Tudzynski B,Studt L

Research topic: Gene Regulation

Sat Sep 01 00:00:00 UTC 2018

Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells.

Investigative ophthalmology & visual science

Sant DW,Camarena V,Mustafi S,Li Y,Wilkes Z,Van Booven D,Wen R,Wang G

Research topic: Stem Cells

Mon Jul 02 00:00:00 UTC 2018

Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos.

eLife

Johnson MR,Stephenson RA,Ghaemmaghami S,Welte MA

Research topic: Gene Regulation

Wed Jul 25 00:00:00 UTC 2018

Elevated H3K79 homocysteinylation causes abnormal gene expression during neural development and subsequent neural tube defects.

Nature communications

Zhang Q,Bai B,Mei X,Wan C,Cao H,Wang S,Zhang M,Wang Z,Wu J,Wang H,Huo J,Ding G,Zhao J,Xie Q,Wang L,Qiu Z,Zhao S,Zhang T

Research topic: Brain & Nerves

Fri Aug 24 00:00:00 UTC 2018

OGT binds a conserved C-terminal domain of TET1 to regulate TET1 activity and function in development.

eLife

Hrit J,Goodrich L,Li C,Wang BA,Nie J,Cui X,Martin EA,Simental E,Fernandez J,Liu MY,Nery JR,Castanon R,Kohli RM,Tretyakova N,He C,Ecker JR,Goll M,Panning B

Research topic: Mammalian puberty & sexual development

Tue Oct 16 00:00:00 UTC 2018

Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation.

eLife

Fuentes DR,Swigut T,Wysocka J

Research topic: Gene Regulation

Thu Aug 02 00:00:00 UTC 2018

EZH2 Inhibition by Tazemetostat Results in Altered Dependency on B-cell Activation Signaling in DLBCL.

Molecular cancer therapeutics

Brach D,Johnston-Blackwell D,Drew A,Lingaraj T,Motwani V,Warholic NM,Feldman I,Plescia C,Smith JJ,Copeland RA,Keilhack H,Chan-Penebre E,Knutson SK,Ribich SA,Raimondi A,Thomenius MJ

Research topic: Lymphoma

Wed Nov 01 00:00:00 UTC 2017

Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells.

PloS one

Topalovic V,Krstic A,Schwirtlich M,Dolfini D,Mantovani R,Stevanovic M,Mojsin M

Research topic: Brain & Nerves

Wed Oct 18 00:00:00 UTC 2017

Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation.

Nature communications

Xu Y,Wang Y,Yan S,Yang Q,Zhou Y,Zeng X,Liu Z,An X,Toque HA,Dong Z,Jiang X,Fulton DJ,Weintraub NL,Li Q,Bagi Z,Hong M,Boison D,Wu C,Huo Y

Research topic: Cardiovascular

Mon Oct 16 00:00:00 UTC 2017

The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression.

Scientific reports

Gonzalez-Vasconcellos I,Schneider R,Anastasov N,Alonso-Rodriguez S,Sanli-Bonazzi B,Fernández JL,Atkinson MJ

Research topic: Osteosarcoma, Telomeres

Tue Feb 07 00:00:00 UTC 2017

Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methylation during Neuronal Differentiation in Brain Development.

Cell reports

Liu J,Wu X,Zhang H,Pfeifer GP,Lu Q

Research topic: Brain & Nerves

Tue Aug 08 00:00:00 UTC 2017

SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.

Cell research

Pan H,Guan D,Liu X,Li J,Wang L,Wu J,Zhou J,Zhang W,Ren R,Zhang W,Li Y,Yang J,Hao Y,Yuan T,Yuan G,Wang H,Ju Z,Mao Z,Li J,Qu J,Tang F,Liu GH

Research topic: Stem Cells

Mon Feb 01 00:00:00 UTC 2016

LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection.

PLoS pathogens

Toth Z,Papp B,Brulois K,Choi YJ,Gao SJ,Jung JU

Research topic: HIV & AIDS

Thu Sep 01 00:00:00 UTC 2016

Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study.

World journal of gastroenterology

Das D,Sarkar N,Sengupta I,Pal A,Saha D,Bandopadhyay M,Das C,Narayan J,Singh SP,Chakravarty R

Research topic: Hepatitis B

Wed Dec 21 00:00:00 UTC 2016

Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification.

F1000Research

Mendoza-Parra MA,Saravaki V,Cholley PE,Blum M,Billoré B,Gronemeyer H

Mon Jun 27 00:00:00 UTC 2016

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.

Nature

Carey BW,Finley LW,Cross JR,Allis CD,Thompson CB

Research topic: Stem Cells

Thu Feb 19 00:00:00 UTC 2015

Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program.

Immunity

Brown CC,Esterhazy D,Sarde A,London M,Pullabhatla V,Osma-Garcia I,Al-Bader R,Ortiz C,Elgueta R,Arno M,de Rinaldis E,Mucida D,Lord GM,Noelle RJ

Research topic: Immunology & Hematology

Tue Mar 17 00:00:00 UTC 2015

NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1.

Nature structural & molecular biology

Aguilar-Arnal L,Katada S,Orozco-Solis R,Sassone-Corsi P

Research topic: Circadian Clock

Wed Apr 01 00:00:00 UTC 2015

Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme.

Clinical epigenetics

Weirich S,Kudithipudi S,Kycia I,Jeltsch A

Research topic: Cancer

Wed Apr 01 00:00:00 UTC 2015

CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET.

American journal of physiology. Lung cellular and molecular physiology

Clifford RL,Patel JK,John AE,Tatler AL,Mazengarb L,Brightling CE,Knox AJ

Research topic: Asthma

Fri May 01 00:00:00 UTC 2015

Histone methylation patterns in astrocytes are influenced by age following ischemia.

Epigenetics

Chisholm NC,Henderson ML,Selvamani A,Park MJ,Dindot S,Miranda RC,Sohrabji F

Research topic: Brain & Nerves

Mon Oct 05 00:00:00 UTC 2015

Chromatin analyses of Zymoseptoria tritici: Methods for chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq).

Fungal genetics and biology : FG & B

Soyer JL,Möller M,Schotanus K,Connolly LR,Galazka JM,Freitag M,Stukenbrock EH

Research topic: Methods - ChIP in fungi

Mon Jun 01 00:00:00 UTC 2015

Chromatin analyses of Zymoseptoria tritici: Methods for chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq).

Fungal genetics and biology : FG & B

Soyer JL,Möller M,Schotanus K,Connolly LR,Galazka JM,Freitag M,Stukenbrock EH

Research topic: Methods - ChIP in fungi

Mon Jun 01 00:00:00 UTC 2015

Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators.

Experimental hematology

Valdez BC,Li Y,Murray D,Ji J,Liu Y,Popat U,Champlin RE,Andersson BS

Research topic: AML

Mon Jun 01 00:00:00 UTC 2015

Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain.

Oncotarget

Gong H,Qian H,Ertl R,Astle CM,Wang GG,Harrison DE,Xu X

Research topic: Neurodegeneration, Alzheimers, Parkinson, Huntington

Tue Jun 30 00:00:00 UTC 2015

MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis.

PLoS genetics

Pham KT,Inoue Y,Vu BV,Nguyen HH,Nakayashiki T,Ikeda K,Nakayashiki H

Research topic: Fungus Pathogenicity

Wed Jul 01 00:00:00 UTC 2015

MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis.

PLoS genetics

Pham KT,Inoue Y,Vu BV,Nguyen HH,Nakayashiki T,Ikeda K,Nakayashiki H

Research topic: Fungus Pathogenicity

Wed Jul 01 00:00:00 UTC 2015

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.

Nature

Ntziachristos P,Tsirigos A,Welstead GG,Trimarchi T,Bakogianni S,Xu L,Loizou E,Holmfeldt L,Strikoudis A,King B,Mullenders J,Becksfort J,Nedjic J,Paietta E,Tallman MS,Rowe JM,Tonon G,Satoh T,Kruidenier L,Prinjha R,Akira S,Van Vlierberghe P,Ferrando AA,Jaenisch R,Mullighan CG,Aifantis I

Research topic: Leukemia

Thu Oct 23 00:00:00 UTC 2014

An epigenomic approach to therapy for tamoxifen-resistant breast cancer.

Cell research

Feng Q,Zhang Z,Shea MJ,Creighton CJ,Coarfa C,Hilsenbeck SG,Lanz R,He B,Wang L,Fu X,Nardone A,Song Y,Bradner J,Mitsiades N,Mitsiades CS,Osborne CK,Schiff R,O'Malley BW

Research topic: Breast Cancer

Tue Jul 01 00:00:00 UTC 2014

Vascular histone deacetylation by pharmacological HDAC inhibition.

Genome research

Rafehi H,Balcerczyk A,Lunke S,Kaspi A,Ziemann M,Kn H,Okabe J,Khurana I,Ooi J,Khan AW,Du XJ,Chang L,Haviv I,Keating ST,Karagiannis TC,El-Osta A

Research topic: Cardiovascular

Fri Aug 01 00:00:00 UTC 2014

In situ histone landscape of nephrogenesis.

Epigenetics

McLaughlin N,Wang F,Saifudeen Z,El-Dahr SS

Research topic: Nephrogenesis

Sat Feb 01 00:00:00 UTC 2014

Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis.

Cell stem cell

Hammoud SS,Low DH,Yi C,Carrell DT,Guccione E,Cairns BR

Research topic: Spermatogenesis, Stem Cells

Thu Aug 07 00:00:00 UTC 2014

Microenvironment promotes tumor cell reprogramming in human breast cancer cell lines.

PloS one

D'Anselmi F,Masiello MG,Cucina A,Proietti S,Dinicola S,Pasqualato A,Ricci G,Dobrowolny G,Catizone A,Palombo A,Bizzarri M

Research topic: Breast Cancer

Sun Aug 31 00:00:00 UTC 2014

Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition.

Epigenetics & chromatin

Cieślik M,Hoang SA,Baranova N,Chodaparambil S,Kumar M,Allison DF,Xu X,Wamsley JJ,Gray L,Jones DR,Mayo MW,Bekiranov S

Research topic: Chromatin Remodeling

Mon Sep 02 00:00:00 UTC 2013

Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest.

Cell stem cell

Rada-Iglesias A,Bajpai R,Prescott S,Brugmann SA,Swigut T,Wysocka J

Research topic: Neurobiology, Developmental Biology

Fri Nov 02 00:00:00 UTC 2012

Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression.

Nucleic acids research

Wallmen B,Schrempp M,Hecht A

Mon Oct 01 00:00:00 UTC 2012

BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression.

PLoS pathogens

Woellmer A,Arteaga-Salas JM,Hammerschmidt W

Research topic: Transcription Regulation

Sat Sep 01 00:00:00 UTC 2012

Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to estrogen-induced phenotypic sex conversion.

Biology of reproduction

Ellis HL,Shioda K,Rosenthal NF,Coser KR,Shioda T

Research topic: Embryonic Sex Differentiation

Sun Jul 01 00:00:00 UTC 2012

Synergistic cytotoxicity of the DNA alkylating agent busulfan, nucleoside analogs and suberoylanilide hydroxamic acid in lymphoma cell lines.

Leukemia & lymphoma

Valdez BC,Murray D,Nieto Y,Li Y,Wang G,Champlin RE,Andersson BS

Research topic: Cancer, Lymphoma

Tue May 01 00:00:00 UTC 2012

Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions.

Cell

Ruthenburg AJ,Li H,Milne TA,Dewell S,McGinty RK,Yuen M,Ueberheide B,Dou Y,Muir TW,Patel DJ,Allis CD

Research topic: Chromatin Structure

Fri May 27 00:00:00 UTC 2011

Global and gene-specific histone modification profiles of mouse multipotent adult germline stem cells.

Molecular human reproduction

Khromov T,Pantakani DV,Nolte J,Wolf M,Dressel R,Engel W,Zechner U

Research topic: Stem Cells

Tue Mar 01 00:00:00 UTC 2011

NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters.

PloS one

Fossati A,Dolfini D,Donati G,Mantovani R

Research topic: Transcription Regulation

Mon Mar 21 00:00:00 UTC 2011

Bioinformatics

Protein Aliases: H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member J; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 K4; H3-clustered histone 13; H3-clustered histone 14; H3-clustered histone 15; H3-clustered histone 2; H3-clustered histone 3; H3-clustered histone 4; H3-clustered histone 6; H3-clustered histone 7; H3/b; H3/d; H3/f; H3/j; H3K4; H3Lys4me3; Hht1p; histone 1, H3a; histone 1, H3b; histone 1, H3f; histone 1, H3h; histone 1, H3j; histone 2, H3a; histone 2, H3c; histone 2, H3c2; histone 2, H3ca2; Histone 3; histone cluster 2, H3c2, pseudogene; histone gene complex 1; Histone H3; Histone H3.1; Histone H3.2; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; Histone H3/m; Histone H3/o; Histone H3K4me3; methyl Histone 3; methyl Histone H3; Tri-methyl H3; Tri-methyl Histone H3; Tri-Methyl-H3 K4; Tri-Methyl-H3 Lys4; Tri-Methyl-Histone H3 K4; Tri-Methyl-Histone H3 Lys4; Trimethyl H3; Trimethyl Histone H3

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Gene Aliases: BUR5; H3; H3-143; H3-291; H3-53; H3-614; H3-B; H3-F; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3/A; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3a; H3b; H3C1; H3C10; H3C11; H3C12; H3C13; H3C14; H3C15; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3F1K; H3F2; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; HHT1; HHT2; Hist1; HIST1H3A; HIST1H3B; Hist1h3c; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2; Hist2h3c2-ps; Hist2h3ca1; Hist2h3ca2; HIST2H3D; M32461; N2749; SIN2; YBR010W; YBR0201; YNL031C

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UniProt ID: (Baker's yeast) P61830, (Human) P68431, (Human) Q71DI3, (Mouse) P68433, (Mouse) P84228, (Mouse) A3KMN6

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Entrez Gene ID: (Baker's yeast) 852295, (Human) 8350, (Human) 8358, (Human) 8968, (Human) 8357, (Human) 8356, (Human) 333932, (Human) 126961, (Mouse) 360198, (Mouse) 319150, (Mouse) 260423, (Mouse) 319152, (Mouse) 97114

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Function(s)

DNA binding protein heterodimerization activity protein binding histone binding cadherin binding involved in cell-cell adhesion

Process(es)

positive regulation of defense response to virus by host nucleosome assembly DNA replication-dependent nucleosome assembly protein heterotetramerization regulation of gene silencing chromatin silencing at rDNA blood coagulation gene silencing by RNA cellular protein metabolic process negative regulation of gene expression, epigenetic positive regulation of gene expression, epigenetic telomere organization cell-cell adhesion xenophagy DNA repair chromatin assembly or disassembly cellular response to DNA damage stimulus mitotic spindle assembly checkpoint rRNA transcription sexual sporulation resulting in formation of a cellular spore global genome nucleotide-excision repair

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Histone H3K4me3 Polyclonal Antibody

Histone H3K4me3 Antibody (39159) in ICC/IF

Product Details

39159

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

ChIP assay (ChIP)

ChIP-sequencing (ChIP-Seq)

Dot blot (DB)

Miscellaneous PubMed (MISC)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

Bioinformatics

Performance Guarantee

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