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Proteintech
HuA/B/C/D Polyclonal Antibody
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Product Details
13032-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HuA/B/C/D Fusion Protein Ag3678 (1-366 aa encoded by BC036071)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MVMIISTME PQVSNGPTSN TSNGPSSNNR NCPSPMQTGA TTDDSKTNLI VNYLPQNMTQ EEFRSLFGSI GEIESCKLVR DKITGQSLGY GFVNYIDPKD AEKAINTLNG LRLQTKTIKV SYARPSSASI RDANLYVSGL PKTMTQKELE QLFSQYGRII TSRILVGQVT GVSRGVGFIR FDKRIEAEEA IKGLNGQKPS GATEPITVKF ANNPSQKSSQ ALLSQLYQSP NRRYPGPLHH QAQRFRLDNL LNMAYGVKRF SPITIDGMTS LVGMNIPGHT GTGWCIFVYN LSPDSDESVL WQLFGPFGAV NNVKVIRDFN TNKCKGFGFV TMTNYDEAAM AITSLNGYRL GDRVLQVSFK TNKAHKS (1-366 aa encoded by BC036071)
Target Information
Embryonic lethal, abnormal vision, Drosophila-like 4 (ELAVL4) is a human homologue of the Drosophila gene ELAV, which is implicated in neuronal differentiation and maintenance. The ELAVL proteins are mRNA binding proteins and all members of the family contain three RNA-recognition motifs. ELAVL-proteins also interact with inflammation-associated factors. The protein may be implicated in neurodegeneration through these complex mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D); ELAV like 1; Elav-like generic protein; ELAV-like neuronal protein 1; ELAV-like neuronal protein 1 isoform Hel-N2; ELAV-like protein 1; ELAV-like protein 2; ELAV-like protein 3; ELAV-like protein 4; embryonic lethal, abnormal vision, drosophila, homolog-like 1; embryonic lethal, abnormal vision-like 2; Hu antigen C; Hu antigen D; Hu antigen R; HU-antigen A; HU-antigen B; HU-antigen C; HU-antigen D; Hu-antigen R; HuB; HuC; HuD; HuR; MelG; Nervous system-specific RNA-binding protein Hel-N1; Nervous system-specific RNA-binding protein Mel-N1; Paraneoplastic cerebellar degeneration-associated antigen; Paraneoplastic encephalomyelitis antigen HuD; Paraneoplastic limbic encephalitis antigen 21; RNA binding protein HuB; RNA-binding protein HUD3
Gene Aliases: 2410055N02Rik; 2600009P04Rik; Elav; ELAV1; Elav2; ELAVL1; ELAVL2; ELAVL3; ELAVL4; Elra; HEL-N1; HELN1; Hua; HUB; HUC; HUCL; HUD; HUR; mel-N1; MelG; mHuC; PLE21; PNEM; r-HuD; RGD1561943; W91709
UniProt ID: (Human) Q15717, (Human) Q13235, (Human) Q14576, (Human) P26378, (Mouse) P70372, (Rat) B5DF91, (Mouse) Q60899, (Mouse) Q60900, (Mouse) Q61701, (Rat) O09032
Entrez Gene ID: (Human) 1994, (Human) 1993, (Human) 1995, (Human) 1996, (Mouse) 15568, (Rat) 363854, (Mouse) 15569, (Rat) 286973, (Mouse) 15571, (Rat) 282824, (Mouse) 15572, (Rat) 432358
mRNA splicing, via spliceosome
multicellular organism development
regulation of mRNA stability
positive regulation of translation
mRNA stabilization
negative regulation of gene silencing by miRNA
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
regulation of transcription, DNA-templated
regulation of translation
nervous system development
cell differentiation
learning
locomotory behavior
neuron differentiation
dendrite morphogenesis
positive regulation of dendrite development
aging
associative learning
regeneration
response to endoplasmic reticulum stress
response to cocaine
cellular response to nerve growth factor stimulus
RNA processing
mRNA processing
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