Proteintech

HuC Polyclonal Antibody

HuC Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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HuC Antibody (55047-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using 55047-1-AP ( HuC antibody at dilution of 1:50 (under 40x lens).

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Product Details

55047-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

RNA Immunoprecipitation (RIP)

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.18 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

The antibody has no cross reaction to other ELAVL members.

Target Information

HUC, belongs to the RRM elav family. It binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA. ELAVL3 may also bind poly-A tracts via RRM 3. It is involved in neuronal differentiation and maintenance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Anaplastic Lymphoma Kinase Overexpression Is Associated with Aggressive Phenotypic Characteristics of Ovarian High-Grade Serous Carcinoma.

The American journal of pathology

Matsumoto T,Oda Y,Hasegawa Y,Hashimura M,Oguri Y,Inoue H,Yokoi A,Tochimoto M,Nakagawa M,Jiang Z,Saegusa M

Fri Oct 01 00:00:00 UTC 2021

HuB and HuD repress telomerase activity by dissociating HuR from TERC.

Nucleic acids research

Cheng X,Gu X,Xia T,Ma Z,Yang Z,Feng HL,Zhao Y,Ma W,Ju Z,Gorospe M,Yi X,Tang H,Wang W

Thu Mar 18 00:00:00 UTC 2021

HuB and HuD repress telomerase activity by dissociating HuR from TERC.

Nucleic acids research

Cheng X,Gu X,Xia T,Ma Z,Yang Z,Feng HL,Zhao Y,Ma W,Ju Z,Gorospe M,Yi X,Tang H,Wang W

Thu Mar 18 00:00:00 UTC 2021

HuB and HuD repress telomerase activity by dissociating HuR from TERC.

Nucleic acids research

Cheng X,Gu X,Xia T,Ma Z,Yang Z,Feng HL,Zhao Y,Ma W,Ju Z,Gorospe M,Yi X,Tang H,Wang W

Thu Mar 18 00:00:00 UTC 2021

Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.

Acta neuropathologica

Diaz-Garcia S,Ko VI,Vazquez-Sanchez S,Chia R,Arogundade OA,Rodriguez MJ,Traynor BJ,Cleveland D,Ravits J

Wed Dec 01 00:00:00 UTC 2021

Nuclear depletion of RNA-binding protein ELAVL3 (HuC) in sporadic and familial amyotrophic lateral sclerosis.

Acta neuropathologica

Diaz-Garcia S,Ko VI,Vazquez-Sanchez S,Chia R,Arogundade OA,Rodriguez MJ,Traynor BJ,Cleveland D,Ravits J

Wed Dec 01 00:00:00 UTC 2021

Choice of Alternative Polyadenylation Sites, Mediated by the RNA-Binding Protein Elavl3, Plays a Role in Differentiation of Inhibitory Neuronal Progenitors.

Frontiers in cellular neuroscience

Grassi E,Santoro R,Umbach A,Grosso A,Oliviero S,Neri F,Conti L,Ala U,Provero P,DiCunto F,Merlo GR

Thu Oct 01 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); ELAV-like protein 3; Hu antigen C; HU-antigen C; HuC; Paraneoplastic cerebellar degeneration-associated antigen; Paraneoplastic limbic encephalitis antigen 21

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Gene Aliases: 2600009P04Rik; ELAVL3; HUC; HUCL; mHuC; PLE21

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UniProt ID: (Human) Q14576, (Mouse) Q60900

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Entrez Gene ID: (Human) 1995, (Mouse) 15571, (Rat) 282824

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Function(s)

nucleotide binding AU-rich element binding nucleic acid binding RNA binding

Process(es)

multicellular organism development nervous system development cell differentiation

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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HuC Polyclonal Antibody

HuC Antibody (55047-1-AP) in IHC (P)

Product Details

55047-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

RNA Immunoprecipitation (RIP)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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