Product References
Vinculin is required for interkinetic nuclear migration (INM) and cell cycle progression.
The Journal of cell biology
Ochoa A,Herrera A,Menendez A,Estefanell M,Ramos C,Pons S
A-21271 was used in Immunohistochemistry to demonstrate that β-catenin targets vinculin to the apical AJs and the centrosome in the embryonic neural tube (NT).
Mon Jan 01 00:00:00 UTC 2024
TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice.
Acta pharmacologica Sinica
Shi CJ,Lian JJ,Zhang BW,Cha JX,Hua QH,Pi XP,Hou YJ,Xie X,Zhang R
A-21271 was used in Immunohistochemistry to provide a method for efficiently converting adult mouse EGCs into neurons by small-molecule compounds, which might be a promising therapeutic strategy for gastrointestinal neuropathy.
Sun Jan 01 00:00:00 UTC 2023
Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in the enteric nervous system.
The Journal of biological chemistry
Ito M,Fujii N,Kohara S,Hori S,Tanaka M,Wittwer C,Kikuchi K,Iijima T,Kakimoto Y,Hirabayashi K,Kurotaki D,Jessen HJ,Saiardi A,Nagata E
A-21271 was used in Immunohistochemistry to reveal an unexpected role of mammalian IP7-a highly active IP6K2-IP7 pathway is conducive to the enteric nervous system.
Wed Mar 01 00:00:00 UTC 2023
Hepatocyte growth factor pretreatment boosts functional recovery after spinal cord injury through human iPSC-derived neural stem/progenitor cell transplantation.
Inflammation and regeneration
Suematsu Y,Nagoshi N,Shinozaki M,Kase Y,Saijo Y,Hashimoto S,Shibata T,Kajikawa K,Kamata Y,Ozaki M,Yasutake K,Shindo T,Shibata S,Matsumoto M,Nakamura M,Okano H
A-21271 was used in Immunohistochemistry to demonstrate that the combined therapeutic approach of HGF preconditioning and hiPSC-NS/PC transplantation enhances locomotor functional recovery post-SCI, highlighting a highly promising therapeutic strategy for acute to subacute SCI.
Mon Oct 16 00:00:00 UTC 2023
Unique activities of two overlapping PAX6 retinal enhancers.
Life science alliance
Uttley K,Papanastasiou AS,Lahne M,Brisbane JM,MacDonald RB,Bickmore WA,Bhatia S
A-21271 was used in Immunohistochemistry-immunofluorescence to demonstrate that unique cell type-specific activities can be uncovered for apparently similar enhancers when investigated at high resolution in vivo.
Wed Nov 01 00:00:00 UTC 2023
Cell competition for neuron-derived trophic factor controls the turnover and lifespan of microglia.
Science advances
Yu T,Kuang H,Wu X,Huang Y,Wang J,Wen Z
A-21271 was used in Immunohistochemistry (Frozen) to reveal cell competition as a general mechanism controlling the turnover and lifespan of microglia.
Fri Jun 16 00:00:00 UTC 2023
Cell competition for neuron-derived trophic factor controls the turnover and lifespan of microglia.
Science advances
Yu T,Kuang H,Wu X,Huang Y,Wang J,Wen Z
A-21271 was used in Immunohistochemistry (Frozen) to reveal cell competition as a general mechanism controlling the turnover and lifespan of microglia.
Fri Jun 16 00:00:00 UTC 2023
New AAV tools fail to detect Neurod1-mediated neuronal conversion of Müller glia and astrocytes in vivo.
EBioMedicine
Xie Y,Zhou J,Wang LL,Zhang CL,Chen B
A-21271 was used in Immunohistochemistry (Frozen) to provide evidence that Neurod1 gene transfer fails to convert lineage traced glial cells into neurons.
Sat Apr 01 00:00:00 UTC 2023
Neogenin expression in ependymo-radial glia of the larval sea lamprey Petromyzon marinus spinal cord.
microPublication biology
González-Llera L,Shifman MI,Barreiro-Iglesias A
A-21271 was used in Immunohistochemistry-immunofluorescence to provide a basis for the future study of the role of neogenin in lamprey ERGs.
Sun May 07 00:00:00 UTC 2023
The macrophages regulate intestinal motility dysfunction through the PGE2 Ptger3 axis during Klebsiella pneumonia sepsis.
Frontiers in immunology
Yao H,Fu X,Xu Q,Li T,Li Y,Kang Y,Wu Q
A-21271 was used in Immunohistochemistry to investigate the mechanisms that activate these cells and the contribution of macrophages to the recovery of intestinal motility dysfunction after sepsis.
Tue Apr 18 00:00:00 UTC 2023
Glyphosate affects the neurochemical phenotype of the intramural neurons in the duodenum in the pig.
Neurogastroenterology and motility
Palus K,Bulc M,Całka J
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to determine the effect of glyphosate intoxication on the neurochemical properties of the enteric nervous system (ENS) neurons located in the wall of the porcine duodenum.
Wed Mar 01 00:00:00 UTC 2023
Single-cell sequencing of individual retinal organoids reveals determinants of cell-fate heterogeneity.
Cell reports methods
Tresenrider A,Sridhar A,Eldred KC,Cuschieri S,Hoffer D,Trapnell C,Reh TA
A-21271 was used in Immunocytochemistry to show sci-Plex's potential to dramatically scale up the analysis of treatment conditions on relevant human models.
Mon Aug 28 00:00:00 UTC 2023
β-Catenin and SOX2 Interaction Regulate Visual Experience-Dependent Cell Homeostasis in the Developing Xenopus Thalamus.
International journal of molecular sciences
Gao J,Lu Y,Luo Y,Duan X,Chen P,Zhang X,Wu X,Qiu M,Shen W
A-21271 was used in Immunohistochemistry to indicate that β-catenin interacts with SOX2 to maintain homeostatic neurogenesis during thalamus development.
Sat Sep 02 00:00:00 UTC 2023
β-Catenin and SOX2 Interaction Regulate Visual Experience-Dependent Cell Homeostasis in the Developing Xenopus Thalamus.
International journal of molecular sciences
Gao J,Lu Y,Luo Y,Duan X,Chen P,Zhang X,Wu X,Qiu M,Shen W
A-21271 was used in Immunohistochemistry to indicate that β-catenin interacts with SOX2 to maintain homeostatic neurogenesis during thalamus development.
Sat Sep 02 00:00:00 UTC 2023
Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer.
Nature communications
Cigliola V,Shoffner A,Lee N,Ou J,Gonzalez TJ,Hoque J,Becker CJ,Han Y,Shen G,Faw TD,Abd-El-Barr MM,Varghese S,Asokan A,Poss KD
A-21271 was used in Immunohistochemistry to identify Hb-egf as a neurogenic factor necessary for innate spinal cord regeneration and suggest strategies to improve spinal cord repair in mammals.
Fri Aug 11 00:00:00 UTC 2023
Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders.
Nature communications
Gracia-Diaz C,Zhou Y,Yang Q,Maroofian R,Espana-Bonilla P,Lee CH,Zhang S,Padilla N,Fueyo R,Waxman EA,Lei S,Otrimski G,Li D,Sheppard SE,Mark P,Harr MH,Hakonarson H,Rodan L,Jackson A,Vasudevan P,Powel C,Mohammed S,Maddirevula S,Alzaidan H,Faqeih EA,Efthymiou S,Turchetti V,Rahman F,Maqbool S,Salpietro V,Ibrahim SH,di Rosa G,Houlden H,Alharbi MN,Al-Sannaa NA,Bauer P,Zifarelli G,Estaras C,Hurst ACE,Thompson ML,Chassevent A,Smith-Hicks CL,de la Cruz X,Holtz AM,Elloumi HZ,Hajianpour MJ,Rieubland C,Braun D,Banka S,French DL,Heller EA,Saade M,Song H,Ming GL,Alkuraya FS,Agrawal PB,Reinberg D,Bhoj EJ,Martínez-Balbás MA,Akizu N
A-21271 was used in Immunohistochemistry to reveal a critical role of EZH1 in neurogenesis regulation and provides molecular diagnosis for previously undefined neurodevelopmental disorders.
Tue Jul 11 00:00:00 UTC 2023
Amyotrophic lateral sclerosis with TDP-43 abnormalities exhibiting globular glial tau inclusions in frontotemporal lobes and pallido-nigral system.
Neuropathology : official journal of the Japanese Society of Neuropathology
Yagita K,Sasagasako N,Koyama S,Noguchi H,Honda H
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to present the autopsy case of an 80-year-old woman with a 9-year history of motor neuron disease and atypical Parkinsonism.
Wed Feb 01 00:00:00 UTC 2023
A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia.
Nature communications
Laddach A,Chng SH,Lasrado R,Progatzky F,Shapiro M,Erickson A,Sampedro Castaneda M,Artemov AV,Bon-Frauches AC,Amaniti EM,Kleinjung J,Boeing S,Ultanir S,Adameyko I,Pachnis V
A-21271 was used in Immunohistochemistry to provide mechanistic insight into the regulatory landscape underpinning the development of intestinal neural circuits and generates a platform for advancing glial cells as therapeutic agents for the treatment of neural deficits.
Fri Sep 22 00:00:00 UTC 2023
Loss of autism-candidate CHD8 perturbs neural crest development and intestinal homeostatic balance.
Life science alliance
Hayot G,Massonot M,Keime C,Faure E,Golzio C
A-21271 was used in Immunocytochemistry to propose a causal developmental link between chd8, NCC development, intestinal homeostasis, and autism-associated gastrointestinal complaints.
Sun Jan 01 00:00:00 UTC 2023
Deterministic and probabilistic fate decisions co-exist in a single retinal lineage.
The EMBO journal
Nerli E,Kretzschmar J,Bianucci T,Rocha-Martins M,Zechner C,Norden C
A-21271 was used in Immunohistochemistry to find that neurogenic progenitor divisions produce two daughter cells, one of deterministic and one of probabilistic fate.
Mon Jul 17 00:00:00 UTC 2023
hapln1a+ cells guide coronary growth during heart morphogenesis and regeneration.
Nature communications
Sun J,Peterson EA,Chen X,Wang J
A-21271 was used in Immunohistochemistry to profile the juvenile zebrafish epicardium during coronary vascularization and identify hapln1a+ cells enriched with vascular-regulating genes.
Tue Jun 13 00:00:00 UTC 2023
Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish.
Neural regeneration research
Song K,Lin Z,Cao L,Lu B,Chen Y,Zhang S,Lu J,Xu H
A-21271 was used in Immunohistochemistry-immunofluorescence to report that Sox11b, a zebrafish Sox11 homolog, regulates the migration and fate determination of Müller glia-derived progenitors (MGPCs) in an adult zebrafish model of mechanical retinal injury.
Wed Feb 01 00:00:00 UTC 2023
Zebrafish pigment cells develop directly from persistent highly multipotent progenitors.
Nature communications
Subkhankulova T,Camargo Sosa K,Uroshlev LA,Nikaido M,Shriever N,Kasianov AS,Yang X,Rodrigues FSLM,Carney TJ,Bavister G,Schwetlick H,Dawes JHP,Rocco A,Makeev VJ,Kelsh RN
A-21271 was used in Immunohistochemistry to find that leukocyte tyrosine kinase early expression marks a multipotent stage, with signalling driving iridophore differentiation through repression of fate-specific transcription factors for other fates.
Mon Mar 06 00:00:00 UTC 2023
Acrylamide-Induced Changes in the Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Immunoreactivity in Small Intestinal Intramural Neurons in Pigs.
International journal of environmental research and public health
Karpiesiuk A,Całka J,Palus K
A-21271 was used in Immunohistochemistry to suggest the participation of PACAP in acrylamide-induced plasticity of enteric neurons, which may be an important line of defense from the harmful action of acrylamide on the small intestines.
Mon Feb 13 00:00:00 UTC 2023
Increasing astrogenesis in the developing hippocampus induces autistic-like behavior in mice via enhancing inhibitory synaptic transmission.
Glia
Chen J,Ma XL,Zhao H,Wang XY,Xu MX,Wang H,Yang TQ,Peng C,Liu SS,Huang M,Zhou YD,Shen Y
A-21271 was used in Immunohistochemistry to provide direct evidence for a developmental role of astrocytes in driving the behavioral phenotypes of ASD.
Sat Jan 01 00:00:00 UTC 2022
Response of Olfactory Sensory Neurons to Mercury Ions in Zebrafish: An Immunohistochemical Study.
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada
Lazzari M,Bettini S,Milani L,Maurizii MG,Franceschini V
A-21271 was used in Immunohistochemistry to conclude that the differential results between dorsal and ventral halves of the olfactory rosette could derive from different water flows inside the olfactory chamber or different subpopulations in OSNs.
Tue Feb 01 00:00:00 UTC 2022
Transduction of Systemically Administered Adeno-Associated Virus in the Colonic Enteric Nervous System and c-Kit Cells of Adult Mice.
Frontiers in neuroanatomy
Wang L,Yuan PQ,Challis C,Ravindra Kumar S,Taché Y
A-21271 was used in Immunohistochemistry-immunofluorescence to demonstrate that in adult mice colon that there is a rostro-caudal decrease in the transduction of systemic delivery of AAV9 and its variants independent of sex.
Tue May 14 00:00:00 UTC 2024
Myostatin is a negative regulator of adult neurogenesis after spinal cord injury in zebrafish.
Cell reports
Saraswathy VM,Zhou L,McAdow AR,Burris B,Dogra D,Reischauer S,Mokalled MH
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to investigate mechanisms of axon regrowth in spinal cord regeneration of zebrafish.
Tue Nov 22 00:00:00 UTC 2022
Reactivation of the Neurogenic Niche in the Adult Zebrafish Statoacoustic Ganglion Following a Mechanical Lesion.
Frontiers in cell and developmental biology
Schwarzer S,Rekhade DR,Machate A,Spieß S,Geffarth M,Ezhkova D,Hans S
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to show that the neurogenic niche of the adult zebrafish SAG can be reactivated to re-enter the cell cycle and to increase neurogenesis upon lesion.
Tue Apr 05 00:00:00 UTC 2022
Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors.
Computational and structural biotechnology journal
Selinger M,Věchtová P,Tykalová H,Ošlejšková P,Rumlová M,Štěrba J,Grubhoffer L
A-21271 was used in Immunocytochemistry to suggest that these factors are responsible for the observed differences in the virulence manifestation of both TBEV strains in different cell lines.
Sat Jul 16 00:00:00 UTC 2022
Immunodetection of P2X2 Receptor in Enteric Nervous System Neurons of the Small Intestine of Pigs.
Animals : an open access journal from MDPI
Mozel S,Arciszewski MB
A-21271 was used in Immunohistochemistry (Frozen) to determine the presence of the P2X2 receptor in the neurons of the enteric nervous system of the pig small intestine (duodenum, jejunum, and ileum) by the immunofluorescence method.
Sat Dec 17 00:00:00 UTC 2022
Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset.
Science advances
Shi X,Zhuang Y,Chen Z,Xu M,Kuang J,Sun XL,Gao L,Kuang X,Zhang H,Li W,Wong SZH,Liu C,Liu L,Jiang D,Pei D,Lin Y,Wu QF
A-21271 was used in Immunohistochemistry (Frozen) to reveal that human TBX3 mutations disturbed the phase separation of encoded proteins and impaired transcriptional regulation of key neuropeptides, providing a pathological mechanism underlying TBX3-associated puberty disorders.
Fri Nov 18 00:00:00 UTC 2022
Olfactory placode generates a diverse population of neurons expressing GnRH, somatostatin mRNA, neuropeptide Y, or calbindin in the chick forebrain.
The Journal of comparative neurology
Murakami S,Ohki-Hamazaki H,Uchiyama Y
A-21271 was used in Immunohistochemistry to indicate that a diverse population of OP-derived neuronal cells, other than GnRH neurons, integrates into the chick medial forebrain.
Thu Dec 01 00:00:00 UTC 2022
Embryonic alcohol exposure disrupts the ubiquitin-proteasome system.
JCI insight
Weeks O,Miller BM,Pepe-Mooney BJ,Oderberg IM,Freeburg SH,Smith CJ,North TE,Goessling W
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to identify the proteasome as a target of EtOH exposure and signify that UPS disruptions contribute to craniofacial, neurological, and endodermal phenotypes in FASDs.
Thu Dec 08 00:00:00 UTC 2022
A new transgenic reporter line reveals expression of protocadherin 9 at a cellular level within the zebrafish central nervous system.
Gene expression patterns : GEP
Habicher J,Manuel R,Pedroni A,Ferebee C,Ampatzis K,Boije H
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to generate a transgenic zebrafish reporter line for pcdh9, detecting the molecule in a portion of internurons within spinal locomotor network.
Wed Jun 01 00:00:00 UTC 2022
Recessive PRDM13 mutations cause fatal perinatal brainstem dysfunction with cerebellar hypoplasia and disrupt Purkinje cell differentiation.
American journal of human genetics
Coolen M,Altin N,Rajamani K,Pereira E,Siquier-Pernet K,Puig Lombardi E,Moreno N,Barcia G,Yvert M,Laquerrière A,Pouliet A,Nitschké P,Boddaert N,Rausell A,Razavi F,Afenjar A,Billette de Villemeur T,Al-Maawali A,Al-Thihli K,Baptista J,Beleza-Meireles A,Garel C,Legendre M,Gelot A,Burglen L,Moutton S,Cantagrel V
A-21271 was used in Immunohistochemistry to identify bi-allelic mutations in PRDM13 as causing a olivopontocerebellar hypoplasia syndrome and suggest that early deregulations of the transcriptional control of neuronal fate specification could contribute to a significant number of cases.
Thu May 05 00:00:00 UTC 2022
Normal aging, motor neurone disease, and Alzheimer's disease are characterized by cortical changes in inflammatory cytokines.
Journal of neuroscience research
Tennakoon A,Katharesan V,Musgrave IF,Koblar SA,Faull RLM,Curtis MA,Johnson IP
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to report that healthy aging and age-related neurodegenerative diseases have different cortical inflammatory signatures that are characterized by increased levels of anti-inflammatory cytokines.
Tue Feb 01 00:00:00 UTC 2022
In toto imaging of early enteric nervous system development reveals that gut colonization is tied to proliferation downstream of Ret.
Development (Cambridge, England)
Baker PA,Ibarra-García-Padilla R,Venkatesh A,Singleton EW,Uribe RA
A-21271 was used in Immunohistochemistry to suggest that Ret signaling may regulate maintenance of a stem state in ENCCs.
Tue Nov 01 00:00:00 UTC 2022
mRNA-Decapping Associated DcpS Enzyme Controls Critical Steps of Neuronal Development.
Cerebral cortex (New York, N.Y. : 1991)
Salamon I,Palsule G,Luo X,Roque A,Tucai S,Khosla I,Volk N,Liu W,Cui H,Pozzo VD,Zalamea P,Jiao X,D'Arcangelo G,Hart RP,Rasin MR,Kiledjian M
A-21271 was used in Immunocytochemistry to demonstrate that the scavenger mRNA decapping activity contributes to multiple pivotal roles in neural development and further corroborate that mRNA metabolism and neocortical pathologies are associated with intellectual disability.
Wed Mar 30 00:00:00 UTC 2022
Embryonic ethanol exposure induces ectopic Hcrt and MCH neurons outside hypothalamus in rats and zebrafish: Role in ethanol-induced behavioural disturbances.
Addiction biology
Collier AD,Yasmin N,Chang GQ,Karatayev O,Khalizova N,Fam M,Abdulai AR,Yu B,Leibowitz SF
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to suggest that the ectopic peptide neurons are functional and contribute to the ethanol-induced behavioural disturbances related to the overconsumption of alcohol.
Tue Nov 01 00:00:00 UTC 2022
Role of mTORC1 activity during early retinal development and lamination in human-induced pluripotent stem cell-derived retinal organoids.
Cell death discovery
Lee SH,Han JW,Yang JY,Jun HO,Bang JH,Shin H,Choi JH,Lee J,Madrakhimov SB,Chung KH,Chang HS,Lyu J,Park TK
A-21271 was used in Immunohistochemistry to identify the time-dependent role of mTORC1 in retinal development, specifically in retinal ganglion cell (RGC) differentiation and the retinal lamination process, during the early stages of retinal organoid (RO) development.
Tue Feb 08 00:00:00 UTC 2022
A New Transgenic Tool to Study the Ret Signaling Pathway in the Enteric Nervous System.
International journal of molecular sciences
Bandla A,Melancon E,Taylor CR,Davidson AE,Eisen JS,Ganz J
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to find that EPCs and the majority of ENS neurons express ret:GFP during ENS development.
Sat Dec 10 00:00:00 UTC 2022
Cre/lox regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration.
eLife
Liu F,Kambakam S,Almeida MP,Ming Z,Welker JM,Wierson WA,Schultz-Rogers LE,Ekker SC,Clark KJ,Essner JJ,McGrail M
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to validate a simplified approach for efficient isolation of Cre/lox-responsive conditional alleles in zebrafish.
Fri Jun 17 00:00:00 UTC 2022
Electroacupuncture at Acupoint ST36 (Zusanli) Improves Intestinal Motility Dysfunction Via Increasing the Proportion of Cholinergic Neurons in Rat Ileal Myenteric Ganglia after Severe Acute Pancreatitis.
Evidence-based complementary and alternative medicine : eCAM
Wang X,Lu L,Zi L,Hu H,Li H,He Y,Li N,Wen Q
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to suggest that EA stimulation at ST36 can partly restore the enteric neuron function and improve intestinal motility dysfunction, therefore could ameliorate SAP. The enteric nervous system can participate in changes in intestinal motility by affecting cholinergic neurons.
Wed Nov 02 00:00:00 UTC 2022
G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis.
Science advances
Rothammer N,Woo MS,Bauer S,Binkle-Ladisch L,Di Liberto G,Egervari K,Wagner I,Haferkamp U,Pless O,Merkler D,Engler JB,Friese MA
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to identify G9a as a critical transcriptional enhancer of neuronal ferroptosis and potential therapeutic target to counteract inflammation-induced neurodegeneration.
Fri Aug 05 00:00:00 UTC 2022
DARPP-32 distinguishes a subset of adult-born neurons in zebra finch HVC.
The Journal of comparative neurology
Aronowitz JV,Kirn JR,Pytte CL,Aaron GB
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to demonstrate and characterize that half of all HVC NNs in zebra finches express DARPP32, receive catecholaminergic input and have transiently larger nuceli than the other half.
Fri Apr 01 00:00:00 UTC 2022
Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity.
Journal of neuroinflammation
Evans EE,Mishra V,Mallow C,Gersz EM,Balch L,Howell A,Reilly C,Smith ES,Fisher TL,Zauderer M
A-21271 was used in Immunohistochemistry to suggest that SEMA4D blockade may ameliorate disease pathology by preserving normal astrocyte function and reducing the negative consequences of reactive astrogliosis.
Sat Aug 06 00:00:00 UTC 2022
zMADM (zebrafish mosaic analysis with double markers) for single-cell gene knockout and dual-lineage tracing.
Proceedings of the National Academy of Sciences of the United States of America
Xu B,Kucenas S,Zong H
A-21271 was used in Immunohistochemistry-immunofluorescence to present a genetic system termed zebrafish mosaic analysis with double markers (zMADM).
Tue Mar 01 00:00:00 UTC 2022
Characterization of Hypothalamic MCH Neuron Development in a 3D Differentiation System of Mouse Embryonic Stem Cells.
eNeuro
Kodani Y,Kawata M,Suga H,Kaneko YS,Nakashima A,Kameyama T,Saito K,Nagasaki H
A-21271 was used in Immunocytochemistry to produce major neurochemical subtypes of melanin-concentrating hormone neurones characterised by the presence or absence of cocaine- and amphetamine- regulated transcript.
Thu Apr 28 00:00:00 UTC 2022
Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy.
Nature communications
Chern T,Achilleos A,Tong X,Hill MC,Saltzman AB,Reineke LC,Chaudhury A,Dasgupta SK,Redhead Y,Watkins D,Neilson JR,Thiagarajan P,Green JBA,Malovannaya A,Martin JF,Rosenblatt DS,Poché RA
A-21271 was used in Immunohistochemistry to identify HCFC1/RONIN as transcriptional regulators of ribosome biogenesis during development and their mutation results in complex syndromes exhibiting aspects of both cblC and ribosomopathies.
Mon Jan 10 00:00:00 UTC 2022
Asymmetric Notch activity by differential inheritance of lysosomes in human neural stem cells.
Science advances
Bohl B,Jabali A,Ladewig J,Koch P
A-21271 was used in Immunocytochemistry to demonstrate that in human neural stem cells (NSCs), lysosomes are asymmetrically inherited during mitosis.
Fri Feb 11 00:00:00 UTC 2022
Quantification of CGRP-immunoreactive myenteric neurons in mouse colon.
The Journal of comparative neurology
Hibberd TJ,Yew WP,Dodds KN,Xie Z,Travis L,Brookes SJ,Costa M,Hu H,Spencer NJ
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to conclude that CGRP+ myenteric neurons in mouse colon were comprehensively quantified, occurring within a range expected of a putative IPAN marker.
Thu Dec 01 00:00:00 UTC 2022
Quantification of CGRP-immunoreactive myenteric neurons in mouse colon.
The Journal of comparative neurology
Hibberd TJ,Yew WP,Dodds KN,Xie Z,Travis L,Brookes SJ,Costa M,Hu H,Spencer NJ
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to conclude that CGRP+ myenteric neurons in mouse colon were comprehensively quantified, occurring within a range expected of a putative IPAN marker.
Thu Dec 01 00:00:00 UTC 2022
Quantification of CGRP-immunoreactive myenteric neurons in mouse colon.
The Journal of comparative neurology
Hibberd TJ,Yew WP,Dodds KN,Xie Z,Travis L,Brookes SJ,Costa M,Hu H,Spencer NJ
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to conclude that CGRP+ myenteric neurons in mouse colon were comprehensively quantified, occurring within a range expected of a putative IPAN marker.
Thu Dec 01 00:00:00 UTC 2022
Quantification of CGRP-immunoreactive myenteric neurons in mouse colon.
The Journal of comparative neurology
Hibberd TJ,Yew WP,Dodds KN,Xie Z,Travis L,Brookes SJ,Costa M,Hu H,Spencer NJ
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to conclude that CGRP+ myenteric neurons in mouse colon were comprehensively quantified, occurring within a range expected of a putative IPAN marker.
Thu Dec 01 00:00:00 UTC 2022
Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina.
eLife
Babu S,Takeuchi Y,Masai I
A-21271 was used in Immunohistochemistry to report that Btg3-associated nuclear protein is indispensable for the DNA damage response and chromosome segregation during mitosis.
Tue Aug 09 00:00:00 UTC 2022
Morphological analysis of the cerebellum and its efferent system in a basal actinopterygian fish, Polypterus senegalus.
The Journal of comparative neurology
Ikenaga T,Shimomai R,Hagio H,Kimura S,Matsumoto K,Kato DI,Uesugi K,Takeuchi A,Yamamoto N,Hibi M
A-21271 was used in Functional assays to investigate the evolution of the cerebellar structure actinopterygians fish.
Wed Jun 01 00:00:00 UTC 2022
Voltage-gated sodium channel scn8a is required for innervation and regeneration of amputated adult zebrafish fins.
Proceedings of the National Academy of Sciences of the United States of America
Osorio-Méndez D,Miller A,Begeman IJ,Kurth A,Hagle R,Rolph D,Dickson AL,Chen CH,Halloran M,Poss KD,Kang J
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to indicate that the activity of VGSCs plays a proregenerative role by promoting innervation of appendage stumps.
Tue Jul 12 00:00:00 UTC 2022
Whole gut imaging allows quantification of all enteric neurons in the adult zebrafish intestine.
Neurogastroenterology and motility
El-Nachef WN,Hu C,Bronner ME
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to study the enteric neurons within the adult zebrafish intestine and assess the relationship between intestinal length and total enteric neuron number.
Tue Feb 01 00:00:00 UTC 2022
Dopaminergic Positron Emission Tomography Imaging in the Alpha-Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease.
Movement disorders : official journal of the Movement Disorder Society
Sossi V,Patterson JR,McCormick S,Kemp CJ,Miller KM,Stoll AC,Kuhn N,Kubik M,Kochmanski J,Luk KC,Sortwell CE
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to investigate multiple aspects of in vivo dopaminergic deficits longitudinally and similarities to human PD using translational PET imaging readouts.
Mon Aug 01 00:00:00 UTC 2022
Effects of exercise on muscle reinnervation and plasticity of spinal circuits in rat sciatic nerve crush injury models with different numbers of crushes.
Muscle & nerve
Minegishi Y,Nishimoto J,Uto M,Ozone K,Oka Y,Kokubun T,Murata K,Takemoto H,Kanemura N
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to examine how different numbers of crushes of the rat sciatic nerve affects muscle reinnervation and plasticity of spinal circuits and the effect of exercise intervention.
Sun May 01 00:00:00 UTC 2022
An early cell shape transition drives evolutionary expansion of the human forebrain.
Cell
Benito-Kwiecinski S,Giandomenico SL,Sutcliffe M,Riis ES,Freire-Pritchett P,Kelava I,Wunderlich S,Martin U,Wray GA,McDole K,Lancaster MA
A-21271 was used in Immunohistochemistry to study developmental mechanisms driving evolutionary brain expansion using cerebral organdies derived from human, gorilla and chimpanzee cells.
Thu Apr 15 00:00:00 UTC 2021
An early cell shape transition drives evolutionary expansion of the human forebrain.
Cell
Benito-Kwiecinski S,Giandomenico SL,Sutcliffe M,Riis ES,Freire-Pritchett P,Kelava I,Wunderlich S,Martin U,Wray GA,McDole K,Lancaster MA
A-21271 was used in Immunohistochemistry to study developmental mechanisms driving evolutionary brain expansion using cerebral organdies derived from human, gorilla and chimpanzee cells.
Thu Apr 15 00:00:00 UTC 2021
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.
Nature genetics
Kameneva P,Artemov AV,Kastriti ME,Faure L,Olsen TK,Otte J,Erickson A,Semsch B,Andersson ER,Ratz M,Frisén J,Tischler AS,de Krijger RR,Bouderlique T,Akkuratova N,Vorontsova M,Gusev O,Fried K,Sundström E,Mei S,Kogner P,Baryawno N,Kharchenko PV,Adameyko I
A-21271 was used in Immunohistochemistry to examine the transcriptional states of neural crest- and mesoderm-derived lineages differentiating into adrenal glands, kidneys, endothelium and hematopoietic tissue between post-conception weeks 6 and 14 of human development.
Sat May 01 00:00:00 UTC 2021
Biallelic variants in LIG3 cause a novel mitochondrial neurogastrointestinal encephalomyopathy.
Brain : a journal of neurology
Bonora E,Chakrabarty S,Kellaris G,Tsutsumi M,Bianco F,Bergamini C,Ullah F,Isidori F,Liparulo I,Diquigiovanni C,Masin L,Rizzardi N,Cratere MG,Boschetti E,Papa V,Maresca A,Cenacchi G,Casadio R,Martelli P,Matera I,Ceccherini I,Fato R,Raiola G,Arrigo S,Signa S,Sementa AR,Severino M,Striano P,Fiorillo C,Goto T,Uchino S,Oyazato Y,Nakamura H,Mishra SK,Yeh YS,Kato T,Nozu K,Tanboon J,Morioka I,Nishino I,Toda T,Goto YI,Ohtake A,Kosaki K,Yamaguchi Y,Nonaka I,Iijima K,Mimaki M,Kurahashi H,Raams A,MacInnes A,Alders M,Engelen M,Linthorst G,de Koning T,den Dunnen W,Dijkstra G,van Spaendonck K,van Gent DC,Aronica EM,Picco P,Carelli V,Seri M,Katsanis N,Duijkers FAM,Taniguchi-Ikeda M,De Giorgio R
A-21271 was used in Immunohistochemistry to study the effect of reduced ligase III (LIG3) activity and resulting mitochondrial dysfunction in seven patients, who showed the common occurrence of gut dysmotility and neurological manifestations reminiscent of mitochondrial neurogastrointestinal encephalomyopathy.
Tue Jun 22 00:00:00 UTC 2021
Dbnl and β-catenin promote pro-N-cadherin processing to maintain apico-basal polarity.
The Journal of cell biology
Herrera A,Menendez A,Torroba B,Ochoa A,Pons S
A-21271 was used in Functional assay to demonstrate that Dbnl and Drebrin-like β-catenin assist in the maturation of pro-N-cadherin, which is critical for AJ formation and for the recruitment AC components like aPKC and, consequently, for the maintenance of apico-basal polarity.
Mon Jun 07 00:00:00 UTC 2021
A single-plasmid approach for genome editing coupled with long-term lineage analysis in chick embryos.
Development (Cambridge, England)
Gandhi S,Li Y,Tang W,Christensen JB,Urrutia HA,Vieceli FM,Piacentino ML,Bronner ME
A-21271 was used in Immunohistochemistry to investigate a single-plasmid approach for genome editing in chick embryos to study experimentally perturbed cells in an otherwise normal embryonic environment.
Thu Apr 01 00:00:00 UTC 2021
Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Cui Q,Pamukcu A,Cherian S,Chang IYM,Berceau BL,Xenias HS,Higgs MH,Rajamanickam S,Chen Y,Du X,Zhang Y,McMorrow H,Abecassis ZA,Boca SM,Justice NJ,Wilson CJ,Chan CS
A-21271 was used in Immunohistochemistry to establish the foundation for future investigations of motor function and disease pathophysiology.
Wed May 05 00:00:00 UTC 2021
Setd1a Plays Pivotal Roles for the Survival and Proliferation of Retinal Progenitors via Histone Modifications of Uhrf1.
Investigative ophthalmology & visual science
Deng X,Iwagawa T,Fukushima M,Suzuki Y,Watanabe S
A-21271 was used in Immunohistochemistry (Frozen) to indicate that Setd1a contributes to the survival and proliferation of retinal cells by regulating histone methylation, Setd1a regulates Uhrf1 expression, and these two molecules cooperate to regulate RPC survival and proliferation.
Mon May 03 00:00:00 UTC 2021
Phosphorylated Tau protein in the myenteric plexus of the ileum and colon of normothermic rats and during synthetic torpor.
Cell and tissue research
Chiocchetti R,Hitrec T,Giancola F,Sadeghinezhad J,Squarcio F,Galiazzo G,Piscitiello E,De Silva M,Cerri M,Amici R,Luppi M
A-21271 was used in Immunohistochemistry to strengthen the hypothesis of a common cellular mechanism triggered by ST, natural hibernation and tauopathies occurring in ENS neurons.
Sat May 01 00:00:00 UTC 2021
Effects of the food additive monosodium glutamate on cisplatin-induced gastrointestinal dysmotility and peripheral neuropathy in the rat.
Neurogastroenterology and motility
López-Tofiño Y,Vera G,López-Gómez L,Girón R,Nurgali K,Uranga JA,Abalo R
A-21271 was used in Immunohistochemistry to test whether MSG may improve gastrointestinal motor dysfunction and other adverse effects induced by repeated cisplatin in rats.
Thu Apr 01 00:00:00 UTC 2021
Cannabinoid and Cannabinoid-Related Receptors in the Myenteric Plexus of the Porcine Ileum.
Animals : an open access journal from MDPI
Toschi A,Galiazzo G,Piva A,Tagliavia C,Mazzuoli-Weber G,Chiocchetti R,Grilli E
A-21271 was used in Immunohistochemistry to immunohistochemically localize the distribution of canonical cannabinoid receptor type 1 (CB1R) and type 2 (CB2R) and the cannabinoid-related receptors transient potential vanilloid receptor 1 (TRPV1), transient potential ankyrin receptor 1 (TRPA1), and serotonin receptor 5-HT1a (5-HT1aR) in the myenteric plexus (MP) of pig ileum.
Thu Jan 21 00:00:00 UTC 2021
Peculiar protrusions along tanycyte processes face diverse neural and nonneural cell types in the hypothalamic parenchyma.
The Journal of comparative neurology
Pasquettaz R,Kolotuev I,Rohrbach A,Gouelle C,Pellerin L,Langlet F
A-21271 was used in Immunohistochemistry-immunofluorescence to lay the neuroanatomical basis for tanycyte/neural cell interactions, which will be useful to further understand cell-to-cell communications involved in the regulation of neuroendocrine functions.
Mon Feb 01 00:00:00 UTC 2021
Developmental delay during eye morphogenesis underlies optic cup and neurogenesis defects in zebrafish mutants.
The International journal of developmental biology
Wycliffe R,Plaisancie J,Leaman S,Santis O,Tucker L,Cavieres D,Fernandez M,Weiss-Garrido C,Sobarzo C,Gestri G,Valdivia LE
A-21271 was used in Immunohistochemistry to study mab21l2 biological function in the developing optic vesicles.
Fri Feb 18 00:00:00 UTC 2022
Structural Identification of the Pacemaker Cells and Expression of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels in the Heart of the Wild Atlantic Cod, Gadus morhua (Linnaeus, 1758).
International journal of molecular sciences
Capillo G,Lauriano ER,Icardo JM,Siriyappagouder P,Kuciel M,Karapanagiotis S,Zaccone G,Fernandes JMO
A-21271 was used in Immunohistochemistry to show that cardiac pacemaking can be modulated by sympathetic and parasympathetic pathways, and the existence of intracardiac neurons projecting back to the central nervous system provide a plausible link between them.
Wed Jul 14 00:00:00 UTC 2021
scRNA-Seq Reveals New Enteric Nervous System Roles for GDNF, NRTN, and TBX3.
Cellular and molecular gastroenterology and hepatology
Wright CM,Schneider S,Smith-Edwards KM,Mafra F,Leembruggen AJL,Gonzalez MV,Kothakapa DR,Anderson JB,Maguire BA,Gao T,Missall TA,Howard MJ,Bornstein JC,Davis BM,Heuckeroth RO
A-21271 was used in Immunohistochemistry to define gene expression in neuron subtypes required for bowl function, to facilitate development of novel therapeutic approaches to treat enteric neuropathies, and to learn more about enteric nervous system function.
Tue Mar 08 00:00:00 UTC 2022
Localization of the Serotonin Transporter in the Dog Intestine and Comparison to the Rat and Human Intestines.
Frontiers in veterinary science
Chiocchetti R,Galiazzo G,Giancola F,Tagliavia C,Bernardini C,Forni M,Pietra M
A-21271 was used in Immunohistochemistry to study the distribution of serotonin transporter (SERT) immunoreactivity in the dog intestine and to compare the findings with those obtained in the rat and human intestines.
Tue Jan 25 00:00:00 UTC 2022
Generating Enteric Nervous System Progenitors from Human Pluripotent Stem Cells.
Current protocols
Gogolou A,Frith TJR,Tsakiridis A
A-21271 was used in Immunocytochemistry to describe in detail a differentiation strategy for the derivation of enteric neural progenitors and neurons from hPSCs through a vagal NC intermediate.
Tue Jun 01 00:00:00 UTC 2021
Heterotrimeric G-protein, Gi1, is involved in the regulation of proliferation, neuronal migration, and dendrite morphology during cortical development in vivo.
Journal of neurochemistry
Hamada N,Iwamoto I,Kawamura N,Nagata KI
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to clarify the role of Gαi1, α-subunit of another Gi/o family member Gi1, during corticogenesis, based on the recent identification of its gene abnormalities in neurodevelopmental disorders.
Sat May 01 00:00:00 UTC 2021
Dystrophin in the Neonatal and Adult Rat Intestine.
Life (Basel, Switzerland)
Lionarons JM,Hoogland G,Slegers RJ,Steinbusch H,Claessen SMH,Vles JSH
A-21271 was used in Immunohistochemistry to study the distribution of dystrophin protein isoform 71 (Dp71) in the neonatal and adult rat intestine.
Fri Oct 29 00:00:00 UTC 2021
Nitrergic and Substance P Immunoreactive Neurons in the Enteric Nervous System of the Bottlenose Dolphin (Tursiops truncatus) Intestine.
Animals : an open access journal from MDPI
Bombardi C,Rambaldi AM,Galiazzo G,Giancola F,Graïc JM,Salamanca G,Cozzi B,Chiocchetti R
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to describe the nitrergic and selected peptidergic systems in the myenteric plexus (MP) and submucosal plexus (SMP) of the intestine of the bottlenose dolphin (Tursiops truncatus).
Thu Apr 08 00:00:00 UTC 2021
Expression of Endogenous Angiotensin-Converting Enzyme 2 in Human Induced Pluripotent Stem Cell-Derived Retinal Organoids.
International journal of molecular sciences
Ahmad Mulyadi Lai HI,Chou SJ,Chien Y,Tsai PH,Chien CS,Hsu CC,Jheng YC,Wang ML,Chiou SH,Chou YB,Hwang DK,Lin TC,Chen SJ,Yang YP
A-21271 was used in Immunocytochemistry to investigate whether ACE2 expression plays a role in human retinal neurons during SARS-CoV-2 infection.
Thu Jan 28 00:00:00 UTC 2021
Intestinal microbiota shapes gut physiology and regulates enteric neurons and glia.
Microbiome
Vicentini FA,Keenan CM,Wallace LE,Woods C,Cavin JB,Flockton AR,Macklin WB,Belkind-Gerson J,Hirota SA,Sharkey KA
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to reveal new insights into the role of the gut microbiota that could lead to therapeutic developments for the treatment of enteric neuropathies.
Tue Oct 26 00:00:00 UTC 2021
Fmrp regulates oligodendrocyte lineage cell specification and differentiation.
Glia
Doll CA,Scott K,Appel B
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to suggest cell stage-specific requirements for Fmrp in the specification and differentiation of oligodendrocyte lineage cells.
Fri Oct 01 00:00:00 UTC 2021
Environmental and Molecular Modulation of Motor Individuality in Larval Zebrafish.
Frontiers in behavioral neuroscience
Hageter J,Waalkes M,Starkey J,Copeland H,Price H,Bays L,Showman C,Laverty S,Bergeron SA,Horstick EJ
A-21271 was used in Immunohistochemistry to investigate the genetic and environmental factors that influence inter-individual variation in larval zebrafish turning preference behavior, with a focus on the role of Notch signaling and neural targets sensitive to environmental and genetic disruptions.
Fri Nov 03 00:00:00 UTC 2023
High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors.
Journal of neuroinflammation
Seguella L,Pesce M,Capuano R,Casano F,Pesce M,Corpetti C,Vincenzi M,Maftei D,Lattanzi R,Del Re A,Sarnelli G,Gulbransen BD,Esposito G
A-21271 was used in Immunohistochemistry to test the hypothesis that anxiogenic and depressive-like behaviors driven by consuming a HFD involve compromised duodenal barrier integrity and subsequent phenotypic changes to glia and neurons along the gut-brain axis.
Sun May 16 00:00:00 UTC 2021
Sonic Hedgehog receptor Patched deficiency in astrocytes enhances glucose metabolism in mice.
Molecular metabolism
Tirou L,Russo M,Faure H,Pellegrino G,Demongin C,Daynac M,Sharif A,Amosse J,Le Lay S,Denis R,Luquet S,Taouis M,Benomar Y,Ruat M
A-21271 was used in Immunohistochemistry to investigated the impact of genetic activation of Sonic hedgehog signaling on hypothalamic astrocytes and characterized its effects on energy metabolism.
Sat May 01 00:00:00 UTC 2021
Quantitative analysis of enteric neurons containing choline acetyltransferase and nitric oxide synthase immunoreactivities in the submucosal and myenteric plexuses of the porcine colon.
Cell and tissue research
Mazzoni M,Caremoli F,Cabanillas L,de Los Santos J,Million M,Larauche M,Clavenzani P,De Giorgio R,Sternini C
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to establish that the ISP contains the highest number of HuC/D neurons/mm2, which were more abundant in AC vs. DC, followed by OSP and MP with similar density in AC and DC.
Mon Feb 01 00:00:00 UTC 2021
Aging impairs the essential contributions of non-glial progenitors to neurorepair in the dorsal telencephalon of the Killifish Nothobranchius furzeri.
Aging cell
Van Houcke J,Mariën V,Zandecki C,Vanhunsel S,Moons L,Ayana R,Seuntjens E,Arckens L
A-21271 was used in Immunohistochemistry to identify abilities of central nervous system regeneration in African turquise killifish.
Wed Sep 01 00:00:00 UTC 2021
Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice.
Nature communications
Mu W,Li S,Xu J,Guo X,Wu H,Chen Z,Qiao L,Helfer G,Lu F,Liu C,Wu QF
A-21271 was used in Immunohistochemistry to offer insights into the properties of tanycytes, which may help to manipulate tanycyte biology for regulating hypothalamic function and investigate the pathogenesis of clinically relevant tumors.
Fri Apr 16 00:00:00 UTC 2021
Fish primary embryonic pluripotent cells assemble into retinal tissue mirroring in vivo early eye development.
eLife
Zilova L,Weinhardt V,Tavhelidse T,Schlagheck C,Thumberger T,Wittbrodt J
A-21271 was used in Immunohistochemistry to derive organoids from rapidly developing teleosts to overcome limitations and address species-specific cellular organisation.
Mon Jul 12 00:00:00 UTC 2021
NOX5 is expressed aberrantly but not a critical pathogenetic gene in Hirschsprung disease.
BMC pediatrics
Wang J,Xiao J,Meng X,Chu X,Zhuansun DD,Xiong B,Feng J
A-21271 was used in Immunocytochemistry to examine the function of NOX5 to verify its role in the development of the enteric nervous system (ENS).
Tue Mar 30 00:00:00 UTC 2021
Zebrafish harbor diverse intestinal macrophage populations including a subset intimately associated with enteric neural processes.
iScience
Graves CL,Chen A,Kwon V,Shiau CE
A-21271 was used in Immunohistochemistry to provide first insights into intestinal macrophages and their association with the enteric nervous system from development to adulthood in teleosts.
Fri Jun 25 00:00:00 UTC 2021
Live Imaging of Primary Neurons in Long-Term Cryopreserved Human Nerve Tissue.
eNeuro
Fortea M,Jain P,Demedts I,Tack J,Vanuytsel T,Cirillo C,Vanden Berghe P
A-21271 was used in Immunohistochemistry-immunofluorescence to demonstrate that the human ENS is a realistic source of primary neurons, which can be successfully preserved over long times and as such can be exploited both for gastrointestinal-specific as well as for general neuroscience research.
Mon Dec 13 00:00:00 UTC 2021
CHAF1A Blocks Neuronal Differentiation and Promotes Neuroblastoma Oncogenesis via Metabolic Reprogramming.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Tao L,Moreno-Smith M,Ibarra-García-Padilla R,Milazzo G,Drolet NA,Hernandez BE,Oh YS,Patel I,Kim JJ,Zorman B,Patel T,Kamal AHM,Zhao Y,Hicks J,Vasudevan SA,Putluri N,Coarfa C,Sumazin P,Perini G,Parchem RJ,Uribe RA,Barbieri E
A-21271 was used in Flow cytometry/Cell sorting to investigate the mechanism by which chromatin assembly factor 1 subunit p150 drives neuroblastoma oncogenesis.
Fri Oct 01 00:00:00 UTC 2021
Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
FEBS open bio
Fukusumi H,Togo K,Sumida M,Nakamori M,Obika S,Baba K,Shofuda T,Ito D,Okano H,Mochizuki H,Kanemura Y
A-21271 was used in Immunocytochemistry to investigate and understand the dynamics and regulation of alpha-synuclein levels in patients with Parkinson's disease.
Mon Feb 01 00:00:00 UTC 2021
Diabetes Affects the Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)-Like Immunoreactive Enteric Neurons in the Porcine Digestive Tract.
International journal of molecular sciences
Palus K,Bulc M,Całka J,Zielonka Ł,Nowicki M
A-21271 was used in Immunohistochemistry to elucidate, for the first time, the impact of prolonged hyperglycaemia conditions on a population of PACAP-like immunoreactive neurons in selected parts of the porcine gastrointestinal tract.
Thu May 27 00:00:00 UTC 2021
Evidence for PKD2L1-positive neurons distant from the central canal in the ventromedial spinal cord and medulla of the adult mouse.
The European journal of neuroscience
Jurčić N,Michelle C,Trouslard J,Wanaverbecq N,Kastner A
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to describe a novel population of PKD2L1+ neurons distant from the CC but with properties similar to CSF-cNs that might serve to sense modification in the composition of either CSF or interstitial liquid, a function that will need to be confirmed.
Sun Aug 01 00:00:00 UTC 2021
Elevated Hoxb5b Expands Vagal Neural Crest Pool and Blocks Enteric Neuronal Development in Zebrafish.
Frontiers in cell and developmental biology
Howard AGA,Nguyen AC,Tworig J,Ravisankar P,Singleton EW,Li C,Kotzur G,Waxman JS,Uribe RA
A-21271 was used in Immunohistochemistry to suggest that while Hoxb5b participates in vagal NCC development as a driver of progenitor expansion, the supernumerary, ectopically localized NCC fail to initiate expansion programs in timely fashion in the gut.
Wed Feb 23 00:00:00 UTC 2022
Toxoplasma gondii infection impairs the colonic motility of rats due to loss of myenteric neurons.
Neurogastroenterology and motility
Machado CCA,Watanabe PDS,Mendes JDL,Pupim ACE,Ortigoza SM,Bergoc HG,Nino BSL,Góis MB,Garcia JL,Blackshaw LA,Sant Ana DMG,Araújo EJA
A-21271 was used in Immunohistochemistry to determine whether colonic coordinated movements are compromised by toxoplasmic infection and how it is associated with anatomical changes.
Fri Jan 01 00:00:00 UTC 2021
HDL biodistribution and brain receptors in zebrafish, using HDLs as vectors for targeting endothelial cells and neural progenitors.
Scientific reports
Sulliman NC,Ghaddar B,Gence L,Patche J,Rastegar S,Meilhac O,Diotel N
A-21271 was used in Immunohistochemistry to suggest the use of HDLs as delivery vectors to target NSCs for drug delivery to boost their neurogenic activity.
Fri Mar 19 00:00:00 UTC 2021
Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies.
Nature medicine
Unlu G,Qi X,Gamazon ER,Melville DB,Patel N,Rushing AR,Hashem M,Al-Faifi A,Chen R,Li B,Cox NJ,Alkuraya FS,Knapik EW
A-21271 was used in Immunohistochemistry to uncover a new mechanism for rare and common diseases resulting from collagen secretion deficits.
Wed Jan 01 00:00:00 UTC 2020
Glial Cell-Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon Structure and Function in Mouse Models of Hirschsprung Disease.
Gastroenterology
Soret R,Schneider S,Bernas G,Christophers B,Souchkova O,Charrier B,Righini-Grunder F,Aspirot A,Landry M,Kembel SW,Faure C,Heuckeroth RO,Pilon N
A-21271 was used in Immunocytochemistry to study whether administration of glial cell derived neurotrophic factor (GDNF) induces enteric nervous system regeneration in mouse models of HSCR.
Sun Nov 01 00:00:00 UTC 2020
SARS-CoV-2 Infects the Brain Choroid Plexus and Disrupts the Blood-CSF Barrier in Human Brain Organoids.
Cell stem cell
Pellegrini L,Albecka A,Mallery DL,Kellner MJ,Paul D,Carter AP,James LC,Lancaster MA
A-21271 was used in Immunohistochemistry-immunofluorescence to show that infection with SARS-CoV-2 damages the choroid plexus epithelium, leading to leakage across this important barrier that normally prevents entry of pathogens, immune cells, and cytokines into cerebrospinal fluid and the brain.
Thu Dec 03 00:00:00 UTC 2020
Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch.
Neuron
Kumamoto T,Maurinot F,Barry-Martinet R,Vaslin C,Vandormael-Pournin S,Le M,Lerat M,Niculescu D,Cohen-Tannoudji M,Rebsam A,Loulier K,Nedelec S,Tozer S,Livet J
A-21271 was used in Immunohistochemistry to introduce an integration-coupled On genetic switch, iOn, which triggers gene expression upon incorporation into the host genome through transposition, thus enabling rapid and accurate identification of integration events following transfection with naked plasmids.
Wed Aug 19 00:00:00 UTC 2020
Ganglioneuromas are driven by activated AKT and can be therapeutically targeted with mTOR inhibitors.
The Journal of experimental medicine
Tao T,Shi H,Wang M,Perez-Atayde AR,London WB,Gutierrez A,Lemos B,Durbin AD,Look AT
A-21271 was used in Immunohistochemistry to propose a clinical trial of mTOR inhibitors as a means to shrink large ganglioneuromas before resection in order to reduce surgical morbidity.
Mon Oct 05 00:00:00 UTC 2020
Reprogramming Axial Level Identity to Rescue Neural-Crest-Related Congenital Heart Defects.
Developmental cell
Gandhi S,Ezin M,Bronner ME
A-21271 was used in Immunohistochemistry to reveal a transcriptional program sufficient to confer cardiac potential onto trunk neural crest cells, thus implicating new genes in cardiovascular birth defects.
Mon May 04 00:00:00 UTC 2020
Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease.
Genome research
Fu AX,Lui KN,Tang CS,Ng RK,Lai FP,Lau ST,Li Z,Garcia-Barcelo MM,Sham PC,Tam PK,Ngan ES,Yip KY
A-21271 was used in Western Blotting to show that a noncoding variant found only in the patients affects the binding of the gliogenesis regulator NFIA, with a corresponding up-regulation of multiple genes in the same topologically associating domain.
Sun Nov 01 00:00:00 UTC 2020
Tanycyte ablation in the arcuate nucleus and median eminence increases obesity susceptibility by increasing body fat content in male mice.
Glia
Yoo S,Cha D,Kim S,Jiang L,Cooke P,Adebesin M,Wolfe A,Riddle R,Aja S,Blackshaw S
A-21271 was used in Immunohistochemistry to demonstrate a role for tanycytes in regulating fat metabolism.
Thu Oct 01 00:00:00 UTC 2020
Microglia senescence occurs in both substantia nigra and ventral tegmental area.
Glia
Shaerzadeh F,Phan L,Miller D,Dacquel M,Hachmeister W,Hansen C,Bechtle A,Tu D,Martcheva M,Foster TC,Kumar A,Streit WJ,Khoshbouei H
A-21271 was used in Immunohistochemistry to test the hypothesis that aging-related changes in microglia and neurons occur in the vulnerable substantia nigra pars compacta but not the ventral tegmental area.
Sun Nov 01 00:00:00 UTC 2020
Targeted cell ablation in zebrafish using optogenetic transcriptional control.
Development (Cambridge, England)
Mruk K,Ciepla P,Piza PA,Alnaqib MA,Chen JK
A-21271 was used in Immunohistochemistry to demonstrate differences between the nitroreductase and M2 systems that influence their efficacies for specific applications.
Wed Jun 17 00:00:00 UTC 2020
De novo enteric neurogenesis in post-embryonic zebrafish from Schwann cell precursors rather than resident cell types.
Development (Cambridge, England)
El-Nachef WN,Bronner ME
A-21271 was used in Immunohistochemistry to suggest that post-embryonic enteric neurogenesis occurs via gut-extrinsic Schwann cell precursors instead of classical glia in zebrafish.
Mon Jul 13 00:00:00 UTC 2020
Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry.
Development (Cambridge, England)
Guglielmi L,Bühler A,Moro E,Argenton F,Poggi L,Carl M
A-21271 was used in Immunohistochemistry to suggest a feedback mechanism whereby the tumor suppressor Wnt inhibitory factor Wif1 controls the Wnt dynamics in the environment of habenular precursor cells.
Mon Mar 16 00:00:00 UTC 2020
Npas1+-Nkx2.1+ Neurons Are an Integral Part of the Cortico-pallido-cortical Loop.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Abecassis ZA,Berceau BL,Win PH,García D,Xenias HS,Cui Q,Pamukcu A,Cherian S,Hernández VM,Chon U,Lim BK,Kim Y,Justice NJ,Awatramani R,Hooks BM,Gerfen CR,Boca SM,Chan CS
A-21271 was used in Immunohistochemistry-immunofluorescence to establish the cellular and circuit substrates that can be important for motor function and dysfunction.
Wed Jan 22 00:00:00 UTC 2020
Dysregulation of external globus pallidus-subthalamic nucleus network dynamics in parkinsonian mice during cortical slow-wave activity and activation.
The Journal of physiology
Kovaleski RF,Callahan JW,Chazalon M,Wokosin DL,Baufreton J,Bevan MD
A-21271 was used in Immunohistochemistry to suggest that in dopamine-depleted mice abnormally correlated and temporally offset PV GPe and STN neuron activity is generated in part by elevated striatopallidal transmission, while compensatory plasticity prevents STN hyperactivity and limits cortical entrainment.
Fri May 01 00:00:00 UTC 2020
Glia-Mediated Regenerative Response Following Acute Excitotoxic Damage in the Postnatal Squamate Retina.
Frontiers in cell and developmental biology
Eymann J,Di-Poï N
A-21271 was used in Immunohistochemistry (Paraffin) to establish and characterise a model of excitotoxic retinal damage in bearded dragon lizard (Pogona vitticeps).
Mon Sep 28 00:00:00 UTC 2020
Development of the intrinsic innervation of the small bowel mucosa and villi.
American journal of physiology. Gastrointestinal and liver physiology
Hao MM,Fung C,Boesmans W,Lowette K,Tack J,Vanden Berghe P
A-21271 was used in Immunohistochemistry to show that enteric neurites project into the lamina propria as early as E13.5 in the mouse, before development of the submucous plexus and before formation of intestinal villi.
Wed Jan 01 00:00:00 UTC 2020
Gender-Related Differences of Tachykinin NK2 Receptor Expression and Activity in Human Colonic Smooth Muscle.
The Journal of pharmacology and experimental therapeutics
Drimousis S,Markus I,Murphy TV,Perera DS,Phan-Thien KC,Zhang L,Liu L
A-21271 was used in Immunohistochemistry to reveal gender-related variations in NK2 receptor activity, signaling transduction pathways, antagonist potency, and changes in expression with age.
Thu Oct 01 00:00:00 UTC 2020
Evaluation of Fluoro-Jade C Staining: Specificity and Application to Damaged Immature Neuronal Cells in the Normal and Injured Mouse Brain.
Neuroscience
Ikenari T,Kurata H,Satoh T,Hata Y,Mori T
A-21271 was used in Western Blot to validate the use of fluoro-Jade C as an appropriate stain for both normal and injured adult and embryonic mouse brains.
Wed Jan 15 00:00:00 UTC 2020
Expression of Repressor Element 1 Silencing Transcription Factor (REST) in Serotonin Neurons in the Adult Male Nile Tilapia (Oreochromis niloticus).
Frontiers in neuroanatomy
Soga T,Nakajima S,Parhar IS
A-21271 was used in Immunocytochemistry to examine the expression of the REST gene in the brain (forebrain, midbrain, and hindbrain) of adult male Nile tilapia (Oreochromis niloticus) using rt-PCR.
Tue Mar 30 00:00:00 UTC 2021
HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory.
Frontiers in neuroanatomy
Pérez-Villegas EM,Pérez-Rodríguez M,Negrete-Díaz JV,Ruiz R,Rosa JL,de Toledo GA,Rodríguez-Moreno A,Armengol JA
A-21271 was used in Immunohistochemistry to study the tbl hippocampus using behavioral tests, ex vivo electrophysiological recordings, immunohistochemistry, the Golgi-Cox method and transmission electron microscopy.
Fri Nov 10 00:00:00 UTC 2023
Zika virus can directly infect and damage the auditory and vestibular components of the embryonic chicken inner ear.
Developmental dynamics : an official publication of the American Association of Anatomists
Thawani A,Sammudin NH,Reygaerts HS,Wozniak AN,Munnamalai V,Kuhn RJ,Fekete DM
A-21271 was used in Immunohistochemistry to present evidence of direct ZIKV infection of developing inner ear epithelium and shows previously unknown inner ear dysmorphogenesis phenotypes.
Wed Jul 01 00:00:00 UTC 2020
Neural cells and their progenitors in regenerating zebrafish spinal cord.
The International journal of developmental biology
Hui SP,Nag TC,Ghosh S
A-21271 was used in Immunohistochemistry to report ultrastructural and cell biological analyses of regeneration processes after spinal cord injury.
Thu Oct 14 00:00:00 UTC 2021
Effect of TNBS-induced colitis on enteric neuronal subpopulations in adult zebrafish.
European journal of histochemistry : EJH
Uyttebroek L,Pype C,Hubens G,Timmermans JP,Van Nassauw L
A-21271 was used in Immunohistochemistry-wholemount to investigate the effect of 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis on changes in enteric neuronal subpopulations in adult zebrafish.
Fri Aug 28 00:00:00 UTC 2020
Colocalization pattern of cocaine- and amphetamine-regulated transcript peptide and parvalbumin immunoreactivity in the hippocampus proper of the chinchilla.
Polish journal of veterinary sciences
Szalak R,Matysek M,Kukula-Koch W,Rycerz K,Zacharko-Siembida A,Arciszewski MB
A-21271 was used in Immunohistochemistry to investigate the distribution and colocalization pattern of cocaine-and amphetamine-regulated transcript (CART) and one of the calcium binding- -proteins: parvalbumin (PV) in the chinchilla's hippocampus proper (HP).
Sun Mar 01 00:00:00 UTC 2020
Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation.
Cell reports
Grubišić V,McClain JL,Fried DE,Grants I,Rajasekhar P,Csizmadia E,Ajijola OA,Watson RE,Poole DP,Robson SC,Christofi FL,Gulbransen BD
A-21271 was used in Immunohistochemistry to identify enteric glia as a critical link between gastrointestinal neural and immune systems that could be harnessed by therapies to ameliorate abdominal pain.
Tue Sep 08 00:00:00 UTC 2020
Distribution of aromatase in the brain of the African cichlid fish Astatotilapia burtoni: Aromatase expression, but not estrogen receptors, varies with female reproductive-state.
The Journal of comparative neurology
Maruska KP,Butler JM,Anselmo C,Tandukar G
A-21271 was used in Immunohistochemistry to investigate the idea that brain-derived estradiol in females may serve important functions in reproductive state-dependent physiological and behavioral processes across vertebrates.
Thu Oct 15 00:00:00 UTC 2020
Vanishing white matter disease expression of truncated EIF2B5 activates induced stress response.
eLife
Keefe MD,Soderholm HE,Shih HY,Stevenson TJ,Glaittli KA,Bowles DM,Scholl E,Colby S,Merchant S,Hsu EW,Bonkowsky JL
A-21271 was used in Immunohistochemistry-immunofluorescence to develop zebrafish efi2b2 as a model of vanishing white matter disease(VMM), and the expression of human EIF2B in the zebrafish eif2b2 mutant rescues lethality and CNS apoptosis.
Thu Dec 10 00:00:00 UTC 2020
ADNP promotes neural differentiation by modulating Wnt/β-catenin signaling.
Nature communications
Sun X,Peng X,Cao Y,Zhou Y,Sun Y
A-21271 was used in Western Blotting to show that ADNP is required for neural induction and differentiation by enhancing Wnt signaling.
Fri Jun 12 00:00:00 UTC 2020
Characterization of gastrointestinal pathologies in the dystonia musculorum mouse model for hereditary sensory and autonomic neuropathy type VI.
Neurogastroenterology and motility
Lynch-Godrei A,De Repentigny Y,Yaworski RA,Gagnon S,Butcher J,Manoogian J,Stintzi A,Kothary R
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to show that parasympathetic GI input showed signs of neurodegeneration, while sympathetic did not.Dstdt-27J GI defects are not linked to ENS neurodegeneration, but are likely a result of an imbalance in autonomic control over the gut.
Wed Apr 01 00:00:00 UTC 2020
The EXTrauterine Environment for Neonatal Development Supports Normal Intestinal Maturation and Development.
Cellular and molecular gastroenterology and hepatology
Baumgarten HD,Wright CM,Rossidis AC,Lawrence KM,Kim AG,Mejaddam AY,McGovern PE,Orr MN,Coons BE,Butt Z,Li H,Hwang G,Radu A,Brown LJ,Rubenstein RC,Peranteau WH,Davey M,Heuckeroth RO,Flake AW
A-21271 was used in Immunohistochemistry (PFA fixed) to determine that the extra-uterine environment for neonatal development supports normal ileal epithelial and enteric nervous system maturation in pre-term lambs.
Tue Sep 07 00:00:00 UTC 2021
Increased (Pro)renin Receptor Expression in the Hypertensive Human Brain.
Frontiers in physiology
Mohsin M,Souza LAC,Aliabadi S,Worker CJ,Cooper SG,Afrin S,Murata Y,Xiong Z,Feng Earley Y
A-21271 was used in Immunohistochemistry-immunofluorescence to show the neural regulation of blood pressure, cardiovascular and metabolic function in humans is mediated by a (pro)renin receptor.
Thu Dec 24 00:00:00 UTC 2020
Defective development and microcirculation of intestine in Npr2 mutant mice.
Scientific reports
Sogawa-Fujiwara C,Hanagata A,Fujiwara Y,Ishida Y,Tomiyasu H,Kunieda T,Nakatomi H,Hori M
A-21271 was used in Immunofluorescence on wholemounted tissues to provide new insights into intractable gastrointestinal (GI) diseases, obesity, and NPR-B signaling.
Tue Sep 08 00:00:00 UTC 2020
Defective development and microcirculation of intestine in Npr2 mutant mice.
Scientific reports
Sogawa-Fujiwara C,Hanagata A,Fujiwara Y,Ishida Y,Tomiyasu H,Kunieda T,Nakatomi H,Hori M
A-21271 was used in Immunofluorescence on wholemounted tissues to provide new insights into intractable gastrointestinal (GI) diseases, obesity, and NPR-B signaling.
Tue Sep 08 00:00:00 UTC 2020
DSCAM regulates delamination of neurons in the developing midbrain.
Science advances
Arimura N,Okada M,Taya S,Dewa KI,Tsuzuki A,Uetake H,Miyashita S,Hashizume K,Shimaoka K,Egusa S,Nishioka T,Yanagawa Y,Yamakawa K,Inoue YU,Inoue T,Kaibuchi K,Hoshino M
A-21271 was used in Immunohistochemistry to show that Down syndrome cell adhesion molecule (DSCAM) controls neuronal delamination by local suppression of the RapGEF2-Rap1-N-cadherin cascade at the apical endfeet in the dorsal midbrain.
Tue Sep 01 00:00:00 UTC 2020
Fast Retrograde Access to Projection Neuron Circuits Underlying Vocal Learning in Songbirds.
Cell reports
Düring DN,Dittrich F,Rocha MD,Tachibana RO,Mori C,Okanoya K,Boehringer R,Ehret B,Grewe BF,Gerber S,Ma S,Rauch M,Paterna JC,Kasper R,Gahr M,Hahnloser RHR
A-21271 was used in Immunohistochemistry-immunofluorescence to present a viral tool that enables fast and efficient retrograde access to projection neuron populations.
Tue Nov 10 00:00:00 UTC 2020
Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain.
Cell reports
Morello F,Borshagovski D,Survila M,Tikker L,Sadik-Ogli S,Kirjavainen A,Estartús N,Knaapi L,Lahti L,Törönen P,Mazutis L,Delogu A,Salminen M,Achim K,Partanen J
A-21271 was used in Immunohistochemistry to characterize the Tal1-dependent and independent neuronal precursors.
Tue Oct 13 00:00:00 UTC 2020
Chronic ingestion of deoxynivalenol-contaminated diet dose-dependently decreases the area of myenteric neurons and gliocytes of rats.
Neurogastroenterology and motility
Rissato DF,de Santi Rampazzo AP,Borges SC,Sousa FC,Busso C,Buttow NC,Natali MRM
A-21271 was used in Immunohistochemistry to investigate effects of deoxynivalenol ingestion in rats.
Wed Apr 01 00:00:00 UTC 2020
Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein.
Molecular neurodegeneration
Landeck N,Strathearn KE,Ysselstein D,Buck K,Dutta S,Banerjee S,Lv Z,Hulleman JD,Hindupur J,Lin LK,Padalkar S,Stanciu LA,Lyubchenko YL,Kirik D,Rochet JC
A-21271 was used in Immunohistochemistry to study α-Synuclein mutations in humans, mice, and human-mouse chimeras and their respective associated pathophysiology.
Tue Sep 08 00:00:00 UTC 2020
Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis.
Cell reports
Fujii K,Nakajo K,Egashira Y,Yamamoto Y,Kitada K,Taniguchi K,Kawai M,Tomiyama H,Kawakami K,Uchiyama K,Ono F
A-21271 was used in Immunohistochemistry to reveal that a population of neurons expressing a hyperpolarization-activated nucleotide-gated channel HCN4 specifically regulates retrograde peristalsis.
Tue Mar 03 00:00:00 UTC 2020
Bsx Is Essential for Differentiation of Multiple Neuromodulatory Cell Populations in the Secondary Prosencephalon.
Frontiers in neuroscience
Schredelseker T,Veit F,Dorsky RI,Driever W
A-21271 was used in Immunohistochemistry to show that most bsx expression domains are dependent on Nkx2.1 and Nkx2.4 homeodomain transcription factors, while a subset depends on Otp.
Mon Sep 28 00:00:00 UTC 2020
ARID1A loss in neuroblastoma promotes the adrenergic-to-mesenchymal transition by regulating enhancer-mediated gene expression.
Science advances
Shi H,Tao T,Abraham BJ,Durbin AD,Zimmerman MW,Kadoch C,Look AT
A-21271 was used in Immunohistochemistry-immunofluorescence to show that disruption of ARID1A homologs in a zebrafish model accelerates the onset and increases the penetrance of MYCN-driven neuroblastoma by increasing cell proliferation in the sympathoadrenal lineage.
Wed Jul 01 00:00:00 UTC 2020
Brain is an endocrine organ through secretion and nuclear transfer of parathymosin.
Life science alliance
Yu B,Tang Y,Cai D
A-21271 was used in Immunohistochemistry to report that parathymosin (PTMS) is secreted by hypothalamic stem/progenitor cells (htNSC) to inhibit senescence of recipient cells such as fibroblasts.
Tue Dec 01 00:00:00 UTC 2020
Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts.
Science advances
Xiao D,Deng Q,Guo Y,Huang X,Zou M,Zhong J,Rao P,Xu Z,Liu Y,Hu Y,Shen Y,Jin K,Xiang M
A-21271 was used in Immunohistochemistry to demonstrate the ability for ABI to reprogram induced RGCs (iRGCs) from fibroblasts.
Fri May 01 00:00:00 UTC 2020
ACE2 Expression in the Cat and the Tiger Gastrointestinal Tracts.
Frontiers in veterinary science
Chiocchetti R,Galiazzo G,Fracassi F,Giancola F,Pietra M
A-21271 was used in immunohistochemistry (frozen) to investigate the expression of ACE2 in the gastrointestinal tract of domestic (cat) and wild (tiger) felines.
Mon Sep 28 00:00:00 UTC 2020
P2X7 receptor antagonist recovers ileum myenteric neurons after experimental ulcerative colitis.
World journal of gastrointestinal pathophysiology
Souza RF,Evangelinellis MM,Mendes CE,Righetti M,Lourenço MCS,Castelucci P
A-21271 was used in Immunohistochemistry to report the effects of BBG in ileum enteric neurons immunoreactive (ir) following experimental ulcerative colitis in Rattus norvegicus albinus.
Sat Jun 20 00:00:00 UTC 2020
Midkine-a functions as a universal regulator of proliferation during epimorphic regeneration in adult zebrafish.
PloS one
Ang NB,Saera-Vila A,Walsh C,Hitchcock PF,Kahana A,Thummel R,Nagashima M
A-21271 was used in Immunohistochemistry to evaluated regeneration of caudal fin, extraocular muscle and retinal neurons to investigate the function of Midkine-a during epimorphic regeneration, using a zebrafish Midkine-a loss of function mutant.
Thu Aug 13 00:00:00 UTC 2020
Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung's disease.
Scientific reports
Dariel A,Grynberg L,Auger M,Lefèvre C,Durand T,Aubert P,Le Berre-Scoul C,Venara A,Suply E,Leclair MD,de Vries P,Levard G,Parmentier B,Podevin G,Schmitt F,Couvrat V,Irtan S,Hervieux E,Villemagne T,Lardy H,Capito C,Muller C,Sarnacki S,Mosnier JF,Galmiche L,Derkinderen P,Boudin H,Brochard C,Neunlist M
A-21271 was used in Immunohistochemistry-immunofluorescence to show that modulating neuronal phenotype and enhancing IEB permeability may treat or prevent postoperative complications in HSCR.
Thu Dec 10 00:00:00 UTC 2020
Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes.
BMC biology
Lavergne A,Tarifeño-Saldivia E,Pirson J,Reuter AS,Flasse L,Manfroid I,Voz ML,Peers B
A-21271 was used in Immunohistochemistry-wholemount to investigate comprehensively the similarity of EECs and PECs by defining their transcriptomic landscape and comparing the regulatory programmes controlled by Pax6b, a key player in both EEC and PEC differentiations.
Mon Aug 31 00:00:00 UTC 2020
Expression of a Barhl1a reporter in subsets of retinal ganglion cells and commissural neurons of the developing zebrafish brain.
Scientific reports
Albadri S,Armant O,Aljand-Geschwill T,Del Bene F,Carl M,Strähle U,Poggi L
A-21271 was used in Immunohistochemistry to explore the spatio-temporal expression of a Barh1a reporter in retinal cells.
Mon Jun 01 00:00:00 UTC 2020
Hedgehog Signaling Regulates Neurogenesis in the Larval and Adult Zebrafish Hypothalamus.
eNeuro
Male I,Ozacar AT,Fagan RR,Loring MD,Shen MC,Pace VA,Devine CA,Lawson GE,Lutservitz A,Karlstrom RO
A-21271 was used in Immunohistochemistry to suggest a mechanism for the control of hypothalamic growth and tissue renewal, as well as the plasticity in neuroendocrine cell populations that is now linked to hypothalamic function.
Fri Jun 18 00:00:00 UTC 2021
A Cellular-Resolution Atlas of the Larval Zebrafish Brain.
Neuron
Kunst M,Laurell E,Mokayes N,Kramer A,Kubo F,Fernandes AM,Förster D,Dal Maschio M,Baier H
A-21271 was used in Immunocytochemistry-immunoflourescence to image over 2,000 GFP-labeled neurons, resulting in an interactive cellular-resolution atlas of the zebrafish brain at 6 days post-fertilization.
Wed Jul 03 00:00:00 UTC 2019
Gene- and tissue-level interactions in normal gastrointestinal development and Hirschsprung disease.
Proceedings of the National Academy of Sciences of the United States of America
Chatterjee S,Nandakumar P,Auer DR,Gabriel SB,Chakravarti A
A-21271 was used in Immunohistochemistry-immunofluorescence to suggest that both cell autonomous and nonautonomous factors, and interactions between the different developing gut tissues, are important for normal ENS development and its disorders.
Thu Dec 26 00:00:00 UTC 2019
Preclinical Assessment of Leptin Transport into the Cerebrospinal Fluid in Diet-Induced Obese Minipigs.
Obesity (Silver Spring, Md.)
Chmielewski A,Hubert T,Descamps A,Mazur D,Daoudi M,Ciofi P,Fontaine C,Caiazzo R,Pattou F,Prevot V,Pigeyre M
A-21271 was used in Immunohistochemistry-immunofluorescence to study the effect of high fat diet on endogenous leptin transport into the central nervous system and hypothalamic sensitivity.
Sat Jun 01 00:00:00 UTC 2019
Structurally defined signaling in neuro-glia units in the enteric nervous system.
Glia
Boesmans W,Hao MM,Fung C,Li Z,Van den Haute C,Tack J,Pachnis V,Vanden Berghe P
A-21271 was used in Immunohistochemistry-immunofluorescence to reveal the spatial and functional foundation of neuro-glia units as an operational cellular assembly in the enteric nervous system.
Sat Jun 01 00:00:00 UTC 2019
Nutrient restriction causes reversible G2 arrest in Xenopus neural progenitors.
Development (Cambridge, England)
McKeown CR,Cline HT
A-21271 was used in Immunohistochemistry to investigate how neural progenitors halt cell division in response to nutrient restriction and subsequently re-enter the cell cycle upon feeding.
Thu Oct 24 00:00:00 UTC 2019
Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Winden KD,Sundberg M,Yang C,Wafa SMA,Dwyer S,Chen PF,Buttermore ED,Sahin M
A-21271 was used in Immunocytochemistry to show that a single mutation in TSC2 is capable of causing mTORC1 hyperactivation and increased synchrony in human iPSC-derived neurons.
Wed Nov 20 00:00:00 UTC 2019
Glucocorticoids Target Ependymal Glia and Inhibit Repair of the Injured Spinal Cord.
Frontiers in cell and developmental biology
Nelson CM,Lennon VA,Lee H,Krug RG,Kamalova A,Madigan NN,Clark KJ,Windebank AJ,Henley JR
A-21271 was used in Immunohistochemistry to examine the mechanism by which glucocorticoids inhibit neural repair following spinal cord injury.
Wed Sep 30 00:00:00 UTC 2020
Novel truncation mutations in MYRF cause autosomal dominant high hyperopia mapped to 11p12-q13.3.
Human genetics
Xiao X,Sun W,Ouyang J,Li S,Jia X,Tan Z,Hejtmancik JF,Zhang Q
A-21271 was used in Immunohistochemistry-immunofluorescence to provide useful clues for further understanding the functional role of the C-terminal region of this critical myelin regulatory factor, as well as the molecular pathogenesis of high hyperopia and its associated angle-closure glaucoma.
Tue Oct 01 00:00:00 UTC 2019
Maternal protein restriction induces gastrointestinal dysfunction and enteric nervous system remodeling in rat offspring.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Aubert P,Oleynikova E,Rizvi H,Ndjim M,Le Berre-Scoul C,Grohard PA,Chevalier J,Segain JP,Le Drean G,Neunlist M,Boudin H
A-21271 was used in Immunohistochemistry-immunofluorescence to show stressors later in life can induce enteric nervous system alterations and gastrointestinal dysfunction as a result of maternal protein restriction.
Tue Jan 01 00:00:00 UTC 2019
Differential nickel-induced responses of olfactory sensory neuron populations in zebrafish.
Aquatic toxicology (Amsterdam, Netherlands)
Lazzari M,Bettini S,Milani L,Maurizii MG,Franceschini V
A-21271 was used in Immunohistochemistry to show that the results of this immunohistochemical study are not in line with those obtained by electro-olfactogram.
Tue Jan 01 00:00:00 UTC 2019
CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection.
Human molecular genetics
Ouyang J,Sun W,Xiao X,Li S,Jia X,Zhou L,Wang P,Zhang Q
A-21271 was used in Immunohistochemistry-immunofluorescence to determine the role of CPSF1 mutations in the development of retinal ganglion cell axon projection.
Sat Jun 15 00:00:00 UTC 2019
Mitotic activity, modulation of DNA processing, and purinergic signalling in the adult rat auditory brainstem following sensory deafferentation.
The European journal of neuroscience
Illing RB,Buschky H,Tadic A
A-21271 was used in Immunohistochemistry to investigate whether mitosis involves in a complex scenario of cellular network reorganization, caused by unilateral sensory deafferentation (USD) in the adult rat central auditory system.
Sun Dec 01 00:00:00 UTC 2019
Endogenous amylin contributes to birth of microglial cells in arcuate nucleus of hypothalamus and area postrema during fetal development.
American journal of physiology. Regulatory, integrative and comparative physiology
Lutz TA,Le Foll C
A-21271 was used in Immunohistochemistry to study the role of amylin in the regulation of of cell birth in the arcuate nucleus and area postrema.
Sat Jun 01 00:00:00 UTC 2019
Epigenetic factors Dnmt1 and Uhrf1 coordinate intestinal development.
Developmental biology
Ganz J,Melancon E,Wilson C,Amores A,Batzel P,Strader M,Braasch I,Diba P,Kuhlman JA,Postlethwait JH,Eisen JS
A-21271 was used in Immunohistochemistry-immunofluorescence to find that functional loss of a DNA methylation machinery component, ubiquitin-like protein containing PHD and RING finger domain 1, leads to reduced numbers of ectoderm-derived enteric neurons and severe disruption of mesoderm-derived intestinal smooth muscle.
Fri Nov 15 00:00:00 UTC 2019
Variations in the proliferative activity of the peripheral retina correlate with postnatal ocular growth in squamate reptiles.
The Journal of comparative neurology
Eymann J,Salomies L,Macrì S,Di-Poï N
A-21271 was used in Immunohistochemistry to study ontogenetic and adult changes in the stem/progenitor activity of the squamate peripheral retina.
Tue Oct 01 00:00:00 UTC 2019
Local heat-shock mediated multi-color labeling visualizing behaviors of enteric neural crest cells associated with division and neurogenesis in zebrafish gut.
Developmental dynamics : an official publication of the American Association of Anatomists
Kuwata M,Nikaido M,Hatta K
A-21271 was used in Immunohistochemistry to introduce a new method of visualizing individual enteric neural crest cells in the zebrafish gut, describe their behaviors associated with cell division, thus providing a foundation to study the mechanism of proliferation and neurogenesis in the enteric nervous system in vertebrates.
Sat Jun 01 00:00:00 UTC 2019
Comprehensive and cell-type-based characterization of the dorsal midbrain during development.
Genes to cells : devoted to molecular & cellular mechanisms
Arimura N,Dewa KI,Okada M,Yanagawa Y,Taya SI,Hoshino M
A-21271 was used in Immunofluorescence in immunohistochemistry on frozen tissues to characterise the ventricular zone, intermediate zone, and marginal zone based on various markers for proliferation and differentiation in embryonic dorsal midbrain.
Tue Jan 01 00:00:00 UTC 2019
Distribution and neuronal circuit of spexin 1/2 neurons in the zebrafish CNS.
Scientific reports
Kim E,Jeong I,Chung AY,Kim S,Kwon SH,Seong JY,Park HC
A-21271 was used in Immunohistochemistry to examine the distribution and neuronal circuit of spexin 1/2 neurons in the zebrafish central nervous system.
Fri Mar 22 00:00:00 UTC 2019
Molecular understanding of label-free second harmonic imaging of microtubules.
Nature communications
Van Steenbergen V,Boesmans W,Li Z,de Coene Y,Vints K,Baatsen P,Dewachter I,Ameloot M,Clays K,Vanden Berghe P
A-21271 was used in Immunocytochemistry-immunoflourescence to identifiy the determinants of the microtubule-dependent second harmonic signal.
Tue Aug 06 00:00:00 UTC 2019
Tanycyte-Independent Control of Hypothalamic Leptin Signaling.
Frontiers in neuroscience
Yoo S,Cha D,Kim DW,Hoang TV,Blackshaw S
A-21271 was used in Immunohistochemistry to analyse the expression and function of the tanycytic leptin receptor in mice.
Wed Sep 30 00:00:00 UTC 2020
Aberrant hiPSCs-Derived from Human Keratinocytes Differentiates into 3D Retinal Organoids that Acquire Mature Photoreceptors.
Cells
Shrestha R,Wen YT,Ding DC,Tsai RK
A-21271 was used in Immunocytochemistry-immunoflourescence to show that human induced pluripotent stem cells with abnormal chromosomal content are permissive to the generation of three-dimensional retinal organoids.
Wed Jan 09 00:00:00 UTC 2019
Looking through Brains with Fast Passive CLARITY: Zebrafish, Rodents, Non-human Primates and Humans.
Bio-protocol
Mortazavi F,Stankiewicz AJ,Zhdanova IV
A-21271 was used in Immunohistochemistry to provide our detailed protocol for PACT (Passive Clarity Technique) in brain tissue of diverse species, including human, non-human primate, rodents, and zebrafish.
Mon Aug 05 00:00:00 UTC 2019
Looking through Brains with Fast Passive CLARITY: Zebrafish, Rodents, Non-human Primates and Humans.
Bio-protocol
Mortazavi F,Stankiewicz AJ,Zhdanova IV
A-21271 was used in Immunohistochemistry to provide our detailed protocol for PACT (Passive Clarity Technique) in brain tissue of diverse species, including human, non-human primate, rodents, and zebrafish.
Mon Aug 05 00:00:00 UTC 2019
Looking through Brains with Fast Passive CLARITY: Zebrafish, Rodents, Non-human Primates and Humans.
Bio-protocol
Mortazavi F,Stankiewicz AJ,Zhdanova IV
A-21271 was used in Immunohistochemistry to provide our detailed protocol for PACT (Passive Clarity Technique) in brain tissue of diverse species, including human, non-human primate, rodents, and zebrafish.
Mon Aug 05 00:00:00 UTC 2019
Looking through Brains with Fast Passive CLARITY: Zebrafish, Rodents, Non-human Primates and Humans.
Bio-protocol
Mortazavi F,Stankiewicz AJ,Zhdanova IV
A-21271 was used in Immunohistochemistry to provide our detailed protocol for PACT (Passive Clarity Technique) in brain tissue of diverse species, including human, non-human primate, rodents, and zebrafish.
Mon Aug 05 00:00:00 UTC 2019
Oxidative Stress-Tolerant Stem Cells from Human Exfoliated Deciduous Teeth Decrease Hydrogen Peroxide-Induced Damage in Organotypic Brain Slice Cultures from Adult Mice.
International journal of molecular sciences
Xiao L,Saiki C,Okamura H
A-21271 was used in Immunohistochemistry-immunofluorescence to study the protective effects of oxidative stress tolerant stem cells harvested from human exfoliated deciduous teeth.
Mon Apr 15 00:00:00 UTC 2019
Microglia are an essential component of the neuroprotective scar that forms after spinal cord injury.
Nature communications
Bellver-Landete V,Bretheau F,Mailhot B,Vallières N,Lessard M,Janelle ME,Vernoux N,Tremblay MÈ,Fuehrmann T,Shoichet MS,Lacroix S
A-21271 was used in Immunohistochemistry-immunofluorescence to assess the response of microglia following spinal cord injury.
Thu Jan 31 00:00:00 UTC 2019
Methamphetamine regulation of activity and topology of ventral midbrain networks.
PloS one
Miller DR,Lebowitz JJ,Guenther DT,Refowich AJ,Hansen C,Maurer AP,Khoshbouei H
A-21271 was used in Immunocytochemistry to establish primary ventral midbrain networks culture as a viable model system that reveals specific changes in network activity, connectivity, and topology modulation by methamphetamine.
Mon Mar 23 00:00:00 UTC 2020
Atlas of the telencephalon based on cytoarchitecture, neurochemical markers, and gene expressions in Rhinogobius flumineus [Mizuno, 1960].
The Journal of comparative neurology
Kawaguchi M,Hagio H,Yamamoto N,Matsumoto K,Nakayama K,Akazome Y,Izumi H,Tsuneoka Y,Suto F,Murakami Y,Ichijo H
A-21271 was used in Immunohistochemistry to describe a telencephalic atlas of a Gobiida species Rhinogobius flumineus based on cytoarchitectural observations, combined with analyses of the distribution patterns of neurochemical markers and transcription factors.
Fri Mar 01 00:00:00 UTC 2019
A genome-wide assessment of the ancestral neural crest gene regulatory network.
Nature communications
Hockman D,Chong-Morrison V,Green SA,Gavriouchkina D,Candido-Ferreira I,Ling ITC,Williams RM,Amemiya CT,Smith JJ,Bronner ME,Sauka-Spengler T
A-21271 was used in Immunohistochemistry-immunofluorescence to provide insight into the core gene regulatory network (GRN) elements conserved to the base of the vertebrates and expose others that are unique to lampreys.
Wed Oct 16 00:00:00 UTC 2019
Alzheimer's disease neuropathological change and loss of matrix/neuropil in patients with idiopathic Normal Pressure Hydrocephalus, a model of Alzheimer's disease.
Acta neuropathologica communications
Libard S,Alafuzoff I
A-21271 was used in Immunohistochemistry to assess unique brain tissue samples, obtained from living subjects with idiopathic Normal Pressure Hydrocephalus.
Wed May 29 00:00:00 UTC 2019
The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming.
Cell reports
Rueda EM,Hall BM,Hill MC,Swinton PG,Tong X,Martin JF,Poché RA
A-21271 was used in Immunohistochemistry-immunofluorescence to reveal that mammalian MGs may have latent regenerative capacity that can be stimulated by repressing Hippo signaling.
Tue May 07 00:00:00 UTC 2019
The Mouse Retinal Organoid Trisection Recipe: Efficient Generation of 3D Retinal Tissue from Mouse Embryonic Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Völkner M,Kurth T,Karl MO
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to differentiate large, stratified retinal organoids from mouse ESCs, perform AAV transfection, cell birth dating, and analyse single organoid gene expression.
Thu Apr 11 00:00:00 UTC 2019
Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation.
Nucleic acids research
Fueyo R,Iacobucci S,Pappa S,Estarás C,Lois S,Vicioso-Mantis M,Navarro C,Cruz-Molina S,Reyes JC,Rada-Iglesias Á,de la Cruz X,Martínez-Balbás MA
A-21271 was used in Immunocytochemistry to examine the mechanisms underlying neural enhancer activation in response to TGFΒ signalling.
Fri Apr 20 00:00:00 UTC 2018
Intracellular Calcium Mobilization Is Required for Sonic Hedgehog Signaling.
Developmental cell
Klatt Shaw D,Gunther D,Jurynec MJ,Chagovetz AA,Ritchie E,Grunwald DJ
A-21271 was used in Immunohistochemistry to study the effect of intracellular calcium mobilisation on the level of Shh dependent cell types in the zebrafish embryo.
Mon May 21 00:00:00 UTC 2018
Temporal and Spatial Post-Transcriptional Regulation of Zebrafish tie1 mRNA by Long Noncoding RNA During Brain Vascular Assembly.
Arteriosclerosis, thrombosis, and vascular biology
Chowdhury TA,Koceja C,Eisa-Beygi S,Kleinstiver BP,Kumar SN,Lin CW,Li K,Prabhudesai S,Joung JK,Ramchandran R
A-21271 was used in Immunohistochemistry to identify a novel mode of temporal and spatial post-transcriptional regulation of tie1 mRNA.
Sun Jul 01 00:00:00 UTC 2018
Identification of Ca2+ signaling components in neural stem/progenitor cells during differentiation into neurons and glia in intact and dissociated zebrafish neurospheres.
Science China. Life sciences
Tse MK,Hung TS,Chan CM,Wong T,Dorothea M,Leclerc C,Moreau M,Miller AL,Webb SE
A-21271 was used in Immunocytochemistry to refine a protocol to generate proliferating and differentiating neurospheres from the entire brain of adult zebrafish.
Thu Nov 01 00:00:00 UTC 2018
Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics.
The Journal of cell biology
Fassier C,Fréal A,Gasmi L,Delphin C,Ten Martin D,De Gois S,Tambalo M,Bosc C,Mailly P,Revenu C,Peris L,Bolte S,Schneider-Maunoury S,Houart C,Nothias F,Larcher JC,Andrieux A,Hazan J
A-21271 was used in Immunohistochemistry-wholemount to identify the meiotic clade adenosine triphosphatase Fidgetin-like 1 as a key growth cone-enriched microtubule-interacting protein in motor circuit wiring and larval locomotion.
Mon May 07 00:00:00 UTC 2018
Notch signalling patterns retinal composition by regulating atoh7 during post-embryonic growth.
Development (Cambridge, England)
Pérez Saturnino A,Lust K,Wittbrodt J
A-21271 was used in Immunohistochemistry-immunofluorescence to elucidate the mechanism by which notch signalling patterns retinal composition.
Fri Nov 09 00:00:00 UTC 2018
Bsx controls pineal complex development.
Development (Cambridge, England)
Schredelseker T,Driever W
A-21271 was used in Immunohistochemistry to identify the differentiation of multiple cell types in the zebrafish pineal complex is due to the brain-specific homeobox gene.
Mon Jul 09 00:00:00 UTC 2018
Leveraging Zebrafish to Study Retinal Degenerations.
Frontiers in cell and developmental biology
Angueyra JM,Kindt KS
A-21271 was used in Immunohistochemistry to studyto study and develop therapies that promote photoreceptor regeneration in mammals.
Wed Mar 13 00:00:00 UTC 2024
Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor, and are required for neural progenitor survival and proliferation.
Disease models & mechanisms
Schultz LE,Haltom JA,Almeida MP,Wierson WA,Solin SL,Weiss TJ,Helmer JA,Sandquist EJ,Shive HR,McGrail M
A-21271 was used in Immunohistochemistry to identify epigenetic regulators driving oncogenesis in a zebrafish retinoblastoma 1 somatic-targeting model of RB1 mutant embryonal brain tumours.
Fri Jun 15 00:00:00 UTC 2018
Establishment of a murine culture system for modeling the temporal progression of cranial and trunk neural crest cell differentiation.
Disease models & mechanisms
Replogle MR,Sreevidya VS,Lee VM,Laiosa MD,Svoboda KR,Udvadia AJ
A-21271 was used in Immunocytochemistry-immunoflourescence to optimise culture conditions for expansion of primary murine neural crest cells that give rise to both ectodermal and mesoectodermal derivatives, even after multiple passages.
Wed Dec 12 00:00:00 UTC 2018
Etiology and functional validation of gastrointestinal motility dysfunction in a zebrafish model of CHARGE syndrome.
The FEBS journal
Cloney K,Steele SL,Stoyek MR,Croll RP,Smith FM,Prykhozhij SV,Brown MM,Midgen C,Blake K,Berman JN
A-21271 was used in Immunohistochemistry-wholemount to highlight the opportunity of the zebrafish to serve as a preclinical model for studying compounds that may improve GI motility in individuals with CHARGE syndrome.
Fri Jun 01 00:00:00 UTC 2018
Anatomical and Functional Changes to the Colonic Neuromuscular Compartment after Experimental Spinal Cord Injury.
Journal of neurotrauma
White AR,Holmes GM
A-21271 was used in Immunohistochemistry to study the colonic alterations that occur after spinal cord injury.
Tue May 01 00:00:00 UTC 2018
Hypoxia activates a neuropeptidergic pathway from the paraventricular nucleus of the hypothalamus to the nucleus tractus solitarii.
American journal of physiology. Regulatory, integrative and comparative physiology
Ruyle BC,Klutho PJ,Baines CP,Heesch CM,Hasser EM
A-21271 was used in Immunohistochemistry to study paraventricular nucleus corticotropin-releasing hormone projections to the nucleus tractus solitarii, as contributors to chemoreflex cardiorespiratory responses.
Sat Dec 01 00:00:00 UTC 2018
Striking parallels between carotid body glomus cell and adrenal chromaffin cell development.
Developmental biology
Hockman D,Adameyko I,Kaucka M,Barraud P,Otani T,Hunt A,Hartwig AC,Sock E,Waithe D,Franck MCM,Ernfors P,Ehinger S,Howard MJ,Brown N,Reese J,Baker CVH
A-21271 was used in Immunohistochemistry to resolve a paradox for the emigre hypothesis in the chicken - where the nearest ganglion to the carotid body is the nodose, in which the satellite glia are neural crest-derived, but the neurons are almost entirely placode-derived - by fate-mapping putative nodose neuronal emiges to the neural crest.
Sat Dec 01 00:00:00 UTC 2018
Multiple zebrafish atoh1 genes specify a diversity of neuronal types in the zebrafish cerebellum.
Developmental biology
Kidwell CU,Su CY,Hibi M,Moens CB
A-21271 was used in Immunohistochemistry-wholemount to report that zebrafish atoh1c-expressing cells are organized in two distinct domains that are separated both by space and developmental time.
Fri Jun 01 00:00:00 UTC 2018
Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling.
Developmental biology
Biehl MJ,Kaylan KB,Thompson RJ,Gonzalez RV,Weis KE,Underhill GH,Raetzman LT
A-21271 was used in Immunohistochemistry (Frozen) to study how Notch signalling effects the development of the anteroventral periventricular nucleus.
Mon Oct 01 00:00:00 UTC 2018
A critical period for the trophic actions of leptin on AgRP neurons in the arcuate nucleus of the hypothalamus.
The Journal of comparative neurology
Kamitakahara A,Bouyer K,Wang CH,Simerly R
A-21271 was used in Immunohistochemistry on frozen tissues to study the critical period of leptin-stimulated Agouti-Related peptide neuron growth in the arcuate nucleus of the hypothalamus.
Mon Jan 01 00:00:00 UTC 2018
Calcineurin B1 Deficiency in Glial Cells Induces Mucosal Degeneration and Inflammation in Mouse Small Intestine.
Biological & pharmaceutical bulletin
Fujita M,Yagi T,Okura U,Tanaka J,Hirashima N,Tanaka M
A-21271 was used in Immunohistochemistry to show the calcineurin B1 deficiency in glial cells impairs the small intestine and leads to malnutrition and eventual death in mice, suggesting that calcineurin plays a novel and important role in enteric glial cells.
Mon Sep 24 00:00:00 UTC 2018
Reduction of the ATPase inhibitory factor 1 (IF1) leads to visual impairment in vertebrates.
Cell death & disease
Martín-Jiménez R,Faccenda D,Allen E,Reichel HB,Arcos L,Ferraina C,Strobbe D,Russell C,Campanella M
A-21271 was used in Immunohistochemistry-immunofluorescence to examine the role of ATPase inhibitor factor 1 in brain development.
Mon Jun 04 00:00:00 UTC 2018
Activating the regenerative potential of Müller glia cells in a regeneration-deficient retina.
eLife
Lust K,Wittbrodt J
A-21271 was used in Immunohistochemistry-immunofluorescence to study the differential response in retinal regeneration between medaka and zebrafish.
Mon Jan 29 00:00:00 UTC 2018
Identification of NeuN immunopositive cells in the adult mouse subventricular zone.
The Journal of comparative neurology
Saito K,Koike T,Kawashima F,Kurata H,Shibuya T,Satoh T,Hata Y,Yamada H,Mori T
A-21271 was used in Immunohistochemistry to indicate that M-SVZ-Ns are a new component of the neurogenic niche and S-SVZ-Ns are newly identified subpopulations of Type A cells.
Wed Aug 15 00:00:00 UTC 2018
Aging-dependent decrease in the numbers of enteric neurons, interstitial cells of Cajal and expression of connexin43 in various regions of gastrointestinal tract.
Aging
Sun T,Li D,Hu S,Huang L,Sun H,Yang S,Wu B,Ji F,Zhou D
A-21271 was used in Western Blotting to study ageing-associated differences between different organs and the exact time to start degenerating.
Tue Dec 11 00:00:00 UTC 2018
Calbindin D28k-Immunoreactivity in Human Enteric Neurons.
International journal of molecular sciences
Zetzmann K,Strehl J,Geppert C,Kuerten S,Jabari S,Brehmer A
A-21271 was used in Immunohistochemistry to discover that several neuron populations display occasional calbindin reactivity, making it unsuitable as a exclusive marker for type III neurons.
Mon Jan 08 00:00:00 UTC 2018
Neuronal connections of the central amygdalar nucleus with refeeding-activated brain areas in rats.
Brain structure & function
Zséli G,Vida B,Szilvásy-Szabó A,Tóth M,Lechan RM,Fekete C
A-21271 was used in Immunohistochemistry to demonstrate the existence of reciprocal connections between the central amygdalar nucleus (CEA) and distinct refeeding-activated hypothalamic, thalamic and brainstem nuclei.
Mon Jan 01 00:00:00 UTC 2018
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.
eLife
Kaczmarek-Hajek K,Zhang J,Kopp R,Grosche A,Rissiek B,Saul A,Bruzzone S,Engel T,Jooss T,Krautloher A,Schuster S,Magnus T,Stadelmann C,Sirko S,Koch-Nolte F,Eulenburg V,Nicke A
A-21271 was used in Immunohistochemistry-immunofluorescence to study neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.
Fri Aug 03 00:00:00 UTC 2018
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular.
BMC genomics
Izuogu OG,Alhasan AA,Mellough C,Collin J,Gallon R,Hyslop J,Mastrorosa FK,Ehrmann I,Lako M,Elliott DJ,Santibanez-Koref M,Jackson MS
A-21271 was used in Immunocytochemistry to analyse lineage specificities of circular RNA in embryonic stem cells.
Fri Apr 20 00:00:00 UTC 2018
Mitochondrial enzyme GLUD2 plays a critical role in glioblastoma progression.
EBioMedicine
Franceschi S,Corsinovi D,Lessi F,Tantillo E,Aretini P,Menicagli M,Scopelliti C,Civita P,Pasqualetti F,Naccarato AG,Ori M,Mazzanti CM
A-21271 was used in Immunohistochemistry to investigate GLUD2 relevance in cancer cell behaviour by GLUD2 overexpression and silencing in two different human glioblastoma cell lines.
Thu Nov 01 00:00:00 UTC 2018
Morphogenesis and motility of the Astyanax mexicanus gastrointestinal tract.
Developmental biology
Riddle MR,Boesmans W,Caballero O,Kazwiny Y,Tabin CJ
A-21271 was used in Immunohistochemistry-immunofluorescence to show that the gastrointestinal tract of the Mexican tetra, Astyanax mexicanus, has distinct regions, exhibiting differences in morphology, motility, and absorption.
Sat Sep 15 00:00:00 UTC 2018
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa.
Nature communications
Buskin A,Zhu L,Chichagova V,Basu B,Mozaffari-Jovin S,Dolan D,Droop A,Collin J,Bronstein R,Mehrotra S,Farkas M,Hilgen G,White K,Pan KT,Treumann A,Hallam D,Bialas K,Chung G,Mellough C,Ding Y,Krasnogor N,Przyborski S,Zwolinski S,Al-Aama J,Alharthi S,Xu Y,Wheway G,Szymanska K,McKibbin M,Inglehearn CF,Elliott DJ,Lindsay S,Ali RR,Steel DH,Armstrong L,Sernagor E,Urlaub H,Pierce E,Lührmann R,Grellscheid SN,Johnson CA,Lako M
A-21271 was used in Immunocytochemistry to study the occurrence of disrupted alternative splicing for specific splicing programmes.
Fri Oct 12 00:00:00 UTC 2018
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival.
Nature communications
Zhou T,Kim TW,Chong CN,Tan L,Amin S,Sadat Badieyan Z,Mukherjee S,Ghazizadeh Z,Zeng H,Guo M,Crespo M,Zhang T,Kenyon R,Robinson CL,Apostolou E,Wang H,Xiang JZ,Evans T,Studer L,Chen S
A-21271 was used in Immunocytochemistry to identify an environmental chemical that contributes to human Β-cell and dopamine neuron loss, and validate a novel human pluripotent stem cells-based platform for determining gene-environment interactions.
Fri Nov 16 00:00:00 UTC 2018
Regeneration of diaphragm with bio-3D cellular patch.
Biomaterials
Zhang XY,Yanagi Y,Sheng Z,Nagata K,Nakayama K,Taguchi T
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot, Immunohistochemistry (Paraffin) to generate large scaffold-free tissue patches composed of human cells.
Fri Jun 01 00:00:00 UTC 2018
Il34-Csf1r Pathway Regulates the Migration and Colonization of Microglial Precursors.
Developmental cell
Wu S,Xue R,Hassan S,Nguyen TML,Wang T,Pan H,Xu J,Liu Q,Zhang W,Wen Z
A-21271 was used in Immunohistochemistry (PFA fixed) to investigate microglial differentiation and migration via the Il34-Csf1ra pathway.
Mon Sep 10 00:00:00 UTC 2018
Intraganglionic macrophages: a new population of cells in the enteric ganglia.
Journal of anatomy
Dora D,Arciero E,Hotta R,Barad C,Bhave S,Kovacs T,Balic A,Goldstein AM,Nagy N
A-21271 was used in Immunocytochemistry to identify a population of macrophages in the enteric ganglia, intermingling with the neurons and glia.
Mon Oct 01 00:00:00 UTC 2018
Quantification and neurochemical coding of the myenteric plexus in humans: No regional variation between the distal colon and rectum.
Neurogastroenterology and motility
Ng KS,Montes-Adrian NA,Mahns DA,Gladman MA
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to use d paired wholemounts to accurately quantify and neurochemically code the hindgut myenteric plexus, comparing human distal colon and rectum.Paired human descending colonic/rectal specimens were procured from 15 patients undergoing anterior resection.
Thu Mar 01 00:00:00 UTC 2018
Cell-specific pallidal intervention induces long-lasting motor recovery in dopamine-depleted mice.
Nature neuroscience
Mastro KJ,Zitelli KT,Willard AM,Leblanc KH,Kravitz AV,Gittis AH
A-21271 was used in Immunohistochemistry to establish the utility of cell-specific interventions in the globus pallidus to target functionally distinct pathways inducing long-lasting recovery of movement.
Thu Jun 01 00:00:00 UTC 2017
Molecular Anatomy of the Developing Human Retina.
Developmental cell
Hoshino A,Ratnapriya R,Brooks MJ,Chaitankar V,Wilken MS,Zhang C,Starostik MR,Gieser L,La Torre A,Nishio M,Bates O,Walton A,Bermingham-McDonogh O,Glass IA,Wong ROL,Swaroop A,Reh TA
A-21271 was used in Immunohistochemistry to define three key epochs in the transcriptome dynamics of human retina from foetal day 52 to 136.
Mon Dec 18 00:00:00 UTC 2017
The Immune Signaling Adaptor LAT Contributes to the Neuroanatomical Phenotype of 16p11.2 BP2-BP3 CNVs.
American journal of human genetics
Loviglio MN,Arbogast T,Jønch AE,Collins SC,Popadin K,Bonnet CS,Giannuzzi G,Maillard AM,Jacquemont S,Yalcin B,Katsanis N,Golzio C,Reymond A
A-21271 was used in Immunohistochemistry to assess how the immune signalling adaptor, LAT, contributes to 16p11.2 220 kb BP2-BP3 copy-number variant-associated neurodevelopmental phenotypes.
Thu Oct 05 00:00:00 UTC 2017
Lef1-dependent hypothalamic neurogenesis inhibits anxiety.
PLoS biology
Xie Y,Kaufmann D,Moulton MJ,Panahi S,Gaynes JA,Watters HN,Zhou D,Xue HH,Fung CM,Levine EM,Letsou A,Brennan KC,Dorsky RI
A-21271 was used in Immunohistochemistry to demonstrate that the Wnt/Β-catenin effector Lef1 is required for the differentiation of anxiolytic hypothalamic neurons in zebrafish and mice.
Tue Aug 01 00:00:00 UTC 2017
The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.
Oncogene
Tao T,Sondalle SB,Shi H,Zhu S,Perez-Atayde AR,Peng J,Baserga SJ,Look AT
A-21271 was used in Immunohistochemistry to indicate that digestive organ expansion factor and other components of the small ribosomal subunit processome provide a novel site of vulnerability in neuroblastoma cells.
Thu Jul 06 00:00:00 UTC 2017
Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool.
Frontiers in molecular neuroscience
Zega K,Jovanovic VM,Vitic Z,Niedzielska M,Knaapi L,Jukic MM,Partanen J,Friedel RH,Lang R,Brodski C
A-21271 was used in Immunohistochemistry on paraffin embedded tissues to study the consequences of genetically inactivating dual-specificity phosphatase 16 on the development of congenital obstructive hydrocephalus and brain overgrowth.
Tue Sep 29 00:00:00 UTC 2020
A novel brain tumour model in zebrafish reveals the role of YAP activation in MAPK- and PI3K-induced malignant growth.
Disease models & mechanisms
Mayrhofer M,Gourain V,Reischl M,Affaticati P,Jenett A,Joly JS,Benelli M,Demichelis F,Poliani PL,Sieger D,Mione M
A21271 was used in immunohistochemistry - paraffin section to propose that neurodevelopmental disorders and brain tumors may arise from changes in oncogenes
Sun Jan 01 00:00:00 UTC 2017
Age-Dependent Alpha-Synuclein Accumulation and Phosphorylation in the Enteric Nervous System in a Transgenic Mouse Model of Parkinson's Disease.
Neuroscience bulletin
Zhong CB,Chen QQ,Haikal C,Li W,Svanbergsson A,Diepenbroek M,Li JY
A-21271 was used in Immunohistochemistry-immunofluorescence to characterise the age-dependent morphological alterations and aggregation of α-synuclein in the enteric nervous system in an α-synuclein transgenic mouse model.
Sun Oct 01 00:00:00 UTC 2017
Octodon degus, a new model to study the agonist and plexus-induced response in the urinary bladder.
Journal of physiology and biochemistry
Martin-Cano FE,Caso-Agundez M,Camello-Almaraz C,Santos FJ,Espin MT,Madrid JA,Diez-Perez A,Camello PJ,Pozo MJ
A21271 was used in immunohistochemistry - paraffin section to study the contractility of the detrusor muscle and the morphology and code of the vesical plexus from Octodon degus
Wed Feb 01 00:00:00 UTC 2017
Sox2 regulates Müller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a.
Experimental eye research
Gorsuch RA,Lahne M,Yarka CE,Petravick ME,Li J,Hyde DR
A-21271 was used in Immunohistochemistry-immunofluorescence to examine if Sox2 is involved in the early reprogramming-like events that Muller glia undergo as they upregulate many pluripotency- and neural stem cell-associated genes required for proliferation in light-damaged adult zebrafish retinas.
Tue Aug 01 00:00:00 UTC 2017
Cellular responses to recurrent pentylenetetrazole-induced seizures in the adult zebrafish brain.
Neuroscience
Duy PQ,Berberoglu MA,Beattie CE,Hall CW
A-21271 was used in Immunohistochemistry to investigate the cellular responses to recurrent pentylenetetrazole seizures in the adult zebrafish brain.
Thu May 04 00:00:00 UTC 2017
CRISPR/Cas9-Mediated Zebrafish Knock-in as a Novel Strategy to Study Midbrain-Hindbrain Boundary Development.
Frontiers in neuroanatomy
Kesavan G,Chekuru A,Machate A,Brand M
A-21271 was used in Immunohistochemistry to generate four CRISPR/Cas9-based knock-in fluorescent reporter lines for otx2 and pax2a, which are involved in midbrain-hindbrain boundary development.
Thu Oct 01 00:00:00 UTC 2020
Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates).
The Journal of comparative neurology
Xavier AL,Fontaine R,Bloch S,Affaticati P,Jenett A,Demarque M,Vernier P,Yamamoto K
A-21271 was used in Immunohistochemistry-immunofluorescence to compare the organisation of cerebrospinal fluid-contacting cells in chicken, Xenopus, and zebrafish.
Thu Jun 15 00:00:00 UTC 2017
Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates).
The Journal of comparative neurology
Xavier AL,Fontaine R,Bloch S,Affaticati P,Jenett A,Demarque M,Vernier P,Yamamoto K
A-21271 was used in Immunohistochemistry-immunofluorescence to compare the organisation of cerebrospinal fluid-contacting cells in chicken, Xenopus, and zebrafish.
Thu Jun 15 00:00:00 UTC 2017
Comparative analysis of monoaminergic cerebrospinal fluid-contacting cells in Osteichthyes (bony vertebrates).
The Journal of comparative neurology
Xavier AL,Fontaine R,Bloch S,Affaticati P,Jenett A,Demarque M,Vernier P,Yamamoto K
A-21271 was used in Immunohistochemistry-immunofluorescence to compare the organisation of cerebrospinal fluid-contacting cells in chicken, Xenopus, and zebrafish.
Thu Jun 15 00:00:00 UTC 2017
A Developmental Study of the Cerebellar Nucleus in the Catshark, a Basal Gnathostome.
Brain, behavior and evolution
Pose-Méndez S,Rodríguez-Moldes I,Candal E,Mazan S,Anadón R
A-21271 was used in Immunohistochemistry to gain insight into the evolution and development of the cerebellar nucleus.
Wed Jul 19 00:00:00 UTC 2017
Distribution and immunohistochemical characteristics of cocaine- and amphetamineregulated transcript-positive nerve elements in the pelvic ganglia of the female pig.
Polish journal of veterinary sciences
Zacharko-Siembida A,Matysek M,Szalak R,Radlińska A,Obszańska K,Arciszewski MB
A-21271 was used in Immunofluorescence in immunohistochemistry on frozen tissues to investigate the distribution patterns of cocaine- and amphetamine-regulated transcript-like immunoreactivity in the pelvic plexus of the female pig.
Tue Mar 28 00:00:00 UTC 2017
MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging.
BMC biology
Ripa R,Dolfi L,Terrigno M,Pandolfini L,Savino A,Arcucci V,Groth M,Terzibasi Tozzini E,Baumgart M,Cellerino A
A21271 was used in immunohistochemistry - frozen section to analyze the role of the microRNA miR-29 in limiting neuronal iron accumulation
Mon Feb 13 00:00:00 UTC 2017
A subset of ipRGCs regulates both maturation of the circadian clock and segregation of retinogeniculate projections in mice.
eLife
Chew KS,Renna JM,McNeill DS,Fernandez DC,Keenan WT,Thomsen MB,Ecker JL,Loevinsohn GS,VanDunk C,Vicarel DC,Tufford A,Weng S,Gray PA,Cayouette M,Herzog ED,Zhao H,Berson DM,Hattar S
A-21271 was used in Immunohistochemistry on frozen tissues to identify a shared developmental mechanism for the maturation of the circadian clock and refinement of eye-specific segregation.
Thu Jun 15 00:00:00 UTC 2017
Localization of the 5-hydroxytryptamine 4 receptor in equine enteric neurons and extrinsic sensory fibers.
Neurogastroenterology and motility
Giancola F,Rambaldi AM,Bianco F,Iusco S,Romagnoli N,Tagliavia C,Bombardi C,Clavenzani P,De Giorgio R,Chiocchetti R
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to evaluate d the distribution of 5-HT4 in the horse intestine and in foals with enteric aganglionosis, reminiscent of human Hirschsprung's disease.
Sat Jul 01 00:00:00 UTC 2017
Enteric innervation combined with proteomics for the evaluation of the effects of chronic fluoride exposure on the duodenum of rats.
Scientific reports
Melo CGS,Perles JVCM,Zanoni JN,Souza SRG,Santos EX,Leite AL,Heubel AD,E Souza CO,Souza JG,Buzalaf MAR
A-21271 was used in Immunohistochemistry-immunofluorescence to evaluate the effects of chronic fluoride exposure on the duodenum in rats.
Fri Apr 21 00:00:00 UTC 2017
Distinct roles of neuroepithelial-like and radial glia-like progenitor cells in cerebellar regeneration.
Development (Cambridge, England)
Kaslin J,Kroehne V,Ganz J,Hans S,Brand M
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to find that neuroepithelial cells are the predominant stem cell type supporting cerebellar regeneration after injury.
Sat Apr 15 00:00:00 UTC 2017
The effects of aging on Amyloid-β42-induced neurodegeneration and regeneration in adult zebrafish brain.
Neurogenesis (Austin, Tex.)
Bhattarai P,Thomas AK,Zhang Y,Kizil C
A-21271 was used in Immunohistochemistry to compare old and young zebrafish to address the effects of ageing on regenerative ability following Amyloid-Β42 deposition.
Fri Mar 18 00:00:00 UTC 2022
Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration.
Acta neuropathologica communications
Yousef A,Robinson JL,Irwin DJ,Byrne MD,Kwong LK,Lee EB,Xu Y,Xie SX,Rennert L,Suh E,Van Deerlin VM,Grossman M,Lee VM,Trojanowski JQ
A-21271 was used in Immunohistochemistry to explore if cortical neurons decreased with increasing TDP-43 inclusion pathology in the postmortem brains of FTLD-TDP patients.
Wed Sep 06 00:00:00 UTC 2017
In Vivo Analysis of the Neurovascular Niche in the Developing Xenopus Brain.
eNeuro
Lau M,Li J,Cline HT
A-21271 was used in Immunohistochemistry to characterise the neurovascular niche during development in the Xenopus laevis tadpole brain.
Thu May 03 00:00:00 UTC 2018
Potent and Selective BACE-1 Peptide Inhibitors Lower Brain Aβ Levels Mediated by Brain Shuttle Transport.
EBioMedicine
Ruderisch N,Schlatter D,Kuglstatter A,Guba W,Huber S,Cusulin C,Benz J,Rufer AC,Hoernschemeyer J,Schweitzer C,Bülau T,Gärtner A,Hoffmann E,Niewoehner J,Patsch C,Baumann K,Loetscher H,Kitas E,Freskgård PO
A-21271 was used in Immunofluorescence to demonstrate that the Brain Shuttle is essential for BACE1 peptide inhibitors to be efficacious in the brain and active-exosite design of BACE1 peptide inhibitors may be of therapeutic relevance.
Sun Oct 01 00:00:00 UTC 2017
A Specific Gut Microbiota Dysbiosis of Type 2 Diabetic Mice Induces GLP-1 Resistance through an Enteric NO-Dependent and Gut-Brain Axis Mechanism.
Cell metabolism
Grasset E,Puel A,Charpentier J,Collet X,Christensen JE,Tercé F,Burcelin R
A-21271 was used in Immunohistochemistry to identify bacterial pathways related to amino acid metabolism and transport system modules associated to GLP-1 resistance.
Tue May 02 00:00:00 UTC 2017
Targeted Pth4-expressing cell ablation impairs skeletal mineralization in zebrafish.
PloS one
Suarez-Bregua P,Saxena A,Bronner ME,Rotllant J
A-21271 was used in Immunohistochemistry to investigate the role of pth4 during skeletal development in zebrafish.
Mon Oct 30 00:00:00 UTC 2017
Neurogenic Radial Glia-like Cells in Meninges Migrate and Differentiate into Functionally Integrated Neurons in the Neonatal Cortex.
Cell stem cell
Bifari F,Decimo I,Pino A,Llorens-Bobadilla E,Zhao S,Lange C,Panuccio G,Boeckx B,Thienpont B,Vinckier S,Wyns S,Bouché A,Lambrechts D,Giugliano M,Dewerchin M,Martin-Villalba A,Carmeliet P
A-21271 was used in Immunohistochemistry to identify radial glia-like cells present in the meninges that migrate and differentiate into functional neurons in the neonatal cerebral cortex.
Thu Mar 02 00:00:00 UTC 2017
Food restriction reduces neurogenesis in the avian hippocampal formation.
PloS one
Robertson BA,Rathbone L,Cirillo G,D'Eath RB,Bateson M,Boswell T,Wilson PW,Dunn IC,Smulders TV
A-21271 was used in Immunohistochemistry to investigate the sensitivity of the avian post-natal and adult neurogenesis to chronic stressors.
Fri Dec 29 00:00:00 UTC 2017
Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus.
eLife
Yuan XS,Wang L,Dong H,Qu WM,Yang SR,Cherasse Y,Lazarus M,Schiffmann SN,d'Exaerde AK,Li RX,Huang ZL
A-21271 was used in Immunohistochemistry-floating tissue to reveal a prominent contribution of striatal A2Areceptors neuron/external globus pallidu parvalbumin neuron circuit in sleep control.
Thu Oct 12 00:00:00 UTC 2017
Arundic Acid Prevents Developmental Upregulation of S100B Expression and Inhibits Enteric Glial Development.
Frontiers in cellular neuroscience
Hao MM,Capoccia E,Cirillo C,Boesmans W,Vanden Berghe P
A21271 was used in immunohistochemistry to evaluate the influences of S100B synthesis in enteric nervous system development
Tue Sep 29 00:00:00 UTC 2020
Testosterone-induced neuroendocrine changes in the medial preoptic area precede song activation and plasticity in song control nuclei of female canaries.
The European journal of neuroscience
Shevchouk OT,Ghorbanpoor S,Ball GF,Cornil CA,Balthazart J
A-21271 was used in Immunohistochemistry to investigate the time course of testosterone action in the song control nuclei and POM, at the gross anatomical and cellular level.
Sat Apr 01 00:00:00 UTC 2017
Effects of exogenous glucagon-like peptide-2 and distal bowel resection on intestinal and systemic adaptive responses in rats.
PloS one
Lai SW,de Heuvel E,Wallace LE,Hartmann B,Holst JJ,Brindle ME,Chelikani PK,Sigalet DL
A-21271 was used in Immunohistochemistry to determine the effects of exogenous glucagon-like peptide-2, with or without massive distal bowel resection, on adaptation of jejunal mucosa, enteric neurons, gut hormones and tissue reserves in rats.
Thu Sep 21 00:00:00 UTC 2017
North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13.
Ophthalmology
Small KW,DeLuca AP,Whitmore SS,Rosenberg T,Silva-Garcia R,Udar N,Puech B,Garcia CA,Rice TA,Fishman GA,Héon E,Folk JC,Streb LM,Haas CM,Wiley LA,Scheetz TE,Fingert JH,Mullins RF,Tucker BA,Stone EM
A-21271 was used in immunocytochemistry to identify mutations that contribute North Carolina macular dystrophy
Fri Jan 01 00:00:00 UTC 2016
Microglial Acid Sensing Regulates Carbon Dioxide-Evoked Fear.
Biological psychiatry
Vollmer LL,Ghosal S,McGuire JL,Ahlbrand RL,Li KY,Santin JM,Ratliff-Rang CA,Patrone LG,Rush J,Lewkowich IP,Herman JP,Putnam RW,Sah R
A-21271 was used in Immunohistochemistry-immunofluorescence to identify TDAG8-dependent microglial acid sensing as a unique chemosensor for detecting and translating hypercapnia to fear-associated behavioral and physiological responses.
Sat Oct 01 00:00:00 UTC 2016
PPARγ Is Activated during Congenital Cytomegalovirus Infection and Inhibits Neuronogenesis from Human Neural Stem Cells.
PLoS pathogens
Rolland M,Li X,Sellier Y,Martin H,Perez-Berezo T,Rauwel B,Benchoua A,Bessières B,Aziza J,Cenac N,Luo M,Casper C,Peschanski M,Gonzalez-Dunia D,Leruez-Ville M,Davrinche C,Chavanas S
A-21271 was used in immunocytochemistry to assess activation during congenital cytomegalovirus infection of PPAR-gamma that inhibits neuronogenesis from human neural stem cells
Fri Apr 01 00:00:00 UTC 2016
Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development.
Development (Cambridge, England)
Klafke R,Prem Anand AA,Wurst W,Prakash N,Wizenmann A
A-21271 was used in immunohistochemistry to compare differences in mouse and chicken development in spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3
Mon Feb 15 00:00:00 UTC 2016
Hypothalamic radial glia function as self-renewing neural progenitors in the absence of Wnt/β-catenin signaling.
Development (Cambridge, England)
Duncan RN,Xie Y,McPherson AD,Taibi AV,Bonkowsky JL,Douglass AD,Dorsky RI
A-21271 was used in Immunohistochemistry to identify the neural progenitor cell population in the larval zebrafish hypothalamus, and to characterize the response and regulation of hypothalamic radial glia during tissue growth and regeneration.
Fri Jan 01 00:00:00 UTC 2016
Thyroid Hormone Acts Locally to Increase Neurogenesis, Neuronal Differentiation, and Dendritic Arbor Elaboration in the Tadpole Visual System.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Thompson CK,Cline HT
A-21271 was used in Immunohistochemistry-wholemount to examine the role of Thyroid hormone in the neurological and visual development of Xenopus laevis tadpoles.
Wed Oct 05 00:00:00 UTC 2016
Changes in Enteric Neurons of Small Intestine in a Rat Model of Irritable Bowel Syndrome with Diarrhea.
Journal of neurogastroenterology and motility
Li S,Fei G,Fang X,Yang X,Sun X,Qian J,Wood JD,Ke M
A-21271 was used in immunohistochemistry to assess histological changes in the distal ileum and intestinal motor function in a rat model of irritable bowel syndrome with diarrhea
Sat Apr 30 00:00:00 UTC 2016
Enteric Dysfunctions in Experimental Parkinson's Disease: Alterations of Excitatory Cholinergic Neurotransmission Regulating Colonic Motility in Rats.
The Journal of pharmacology and experimental therapeutics
Fornai M,Pellegrini C,Antonioli L,Segnani C,Ippolito C,Barocelli E,Ballabeni V,Vegezzi G,Al Harraq Z,Blandini F,Levandis G,Cerri S,Blandizzi C,Bernardini N,Colucci R
A-21271 was used in immunohistochemistry to assess the impact of central dopaminergic denervation on distal colonic excitatory cholinergic neuromotor activity in rats
Mon Feb 01 00:00:00 UTC 2016
The zebrafish mutant lessen: an experimental model for congenital enteric neuropathies.
Neurogastroenterology and motility
Uyttebroek L,Shepherd IT,Vanden Berghe P,Hubens G,Timmermans JP,Van Nassauw L
A-21271 was used in immunohistochemistry to elucidate the zebrafish model and congenital enteric neuropathies
Tue Mar 01 00:00:00 UTC 2016
Electrophysiological and morphological changes in colonic myenteric neurons from chemotherapy-treated patients: a pilot study.
Neurogastroenterology and motility
Carbone SE,Jovanovska V,Brookes SJ,Nurgali K
A-21271 was used in Immunohistochemistry to determine whether the function and morphology of myenteric neurons was altered in specimens of the colon from chemotherapy-treated patients.
Fri Jul 01 00:00:00 UTC 2016
Reporter mouse strain provides a novel look at angiotensin type-2 receptor distribution in the central nervous system.
Brain structure & function
de Kloet AD,Wang L,Ludin JA,Smith JA,Pioquinto DJ,Hiller H,Steckelings UM,Scheuer DA,Sumners C,Krause EG
A-21271 was used in Immunohistochemistry to examine angiotensin type-2 receptor distribution in the central nervous system.
Tue Mar 01 00:00:00 UTC 2016
Early developmental stress negatively affects neuronal recruitment to avian song system nucleus HVC.
Developmental neurobiology
Honarmand M,Thompson CK,Schatton A,Kipper S,Scharff C
A-21271 was used in immunohistochemistry - free floating to test if nutrition-related developmental stress impacts neurogenesis in HVC in song birds
Fri Jan 01 00:00:00 UTC 2016
Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish.
Developmental neurobiology
Stil A,Drapeau P
A-21271 was used in immunocytochemistry and immunohistochemistry to describe neuronal patterns in the spinal cord of adult zebrafish.
Wed Jun 01 00:00:00 UTC 2016
Elucidation of the anatomy of a satiety network: Focus on connectivity of the parabrachial nucleus in the adult rat.
The Journal of comparative neurology
Zséli G,Vida B,Martinez A,Lechan RM,Khan AM,Fekete C
A-21271 was used in immunohistochemistry - frozen section to study the anatomy of the satiety network by focusing on connectivity of the parabrachial nucleus in the adult rat
Sat Oct 01 00:00:00 UTC 2016
L1.2, the zebrafish paralog of L1.1 and ortholog of the mammalian cell adhesion molecule L1 contributes to spinal cord regeneration in adult zebrafish.
Restorative neurology and neuroscience
Chen T,Yu Y,Hu C,Schachner M
A-21271 was used in immunohistochemistry - frozen section to study contribution to spinal cord regeneration in adult zebrafish by L1.2, the zebrafish paralog of L1.1 and ortholog of the mammalian cell adhesion molecule L1
Mon Dec 19 00:00:00 UTC 2016
Molecular fingerprinting delineates progenitor populations in the developing zebrafish enteric nervous system.
Developmental dynamics : an official publication of the American Association of Anatomists
Taylor CR,Montagne WA,Eisen JS,Ganz J
A-21271 was used in Immunohistochemistry-immunofluorescence to propose that a progenitor's expression profile reveals its developmental state, and this indicates developmental restrictions.
Tue Nov 01 00:00:00 UTC 2016
Galanin regulates blood glucose level in the zebrafish: a morphological and functional study.
Histochemistry and cell biology
Podlasz P,Jakimiuk A,Chmielewska-Krzesinska M,Kasica N,Nowik N,Kaleczyc J
A-21271 was used in immunohistochemistry - frozen section to study galaninergic innervation
Fri Jan 01 00:00:00 UTC 2016
Desired and side effects of the supplementation with l-glutamine and l-glutathione in enteric glia of diabetic rats.
Acta histochemica
Panizzon CPDNB,Zanoni JN,Hermes-Uliana C,Trevizan AR,Sehaber CC,Pereira RVF,Linden DR,Neto MHM
A21271 was used in immunohistochemistry to compare the effects of supplementation with l-glutamine and l-glutathione on neurons and enteric glial cells in ileum of diabetic rats
Fri Jul 01 00:00:00 UTC 2016
Large-scale tissue clearing (PACT): Technical evaluation and new perspectives in immunofluorescence, histology, and ultrastructure.
Scientific reports
Neckel PH,Mattheus U,Hirt B,Just L,Mack AF
A-21271 was used in immunohistochemistry - paraffin section use CLARITY and PACT to visualize the intestinal architecture
Thu Sep 29 00:00:00 UTC 2016
Single-cell in vivo imaging of adult neural stem cells in the zebrafish telencephalon.
Nature protocols
Barbosa JS,Di Giaimo R,Götz M,Ninkovic J
A-21271 was used in Immunohistochemistry to describe a protocol for labeling and repetitive imaging of aNSCs in vivo.
Mon Aug 01 00:00:00 UTC 2016
Galectin-3 causes enteric neuronal loss in mice after left sided permanent middle cerebral artery occlusion, a model of stroke.
Scientific reports
Cheng X,Boza-Serrano A,Turesson MF,Deierborg T,Ekblad E,Voss U
A-21271 was used in immunohistochemistry - frozen section demonstrate that stroke results in central and peripheral galectin-3 release causing enteric neuronal loss through a TLR4-mediated mechanism
Fri Sep 09 00:00:00 UTC 2016
Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain.
eLife
He S,Mansour MR,Zimmerman MW,Ki DH,Layden HM,Akahane K,Gjini E,de Groh ED,Perez-Atayde AR,Zhu S,Epstein JA,Look AT
A-21271 was used in immunohistochemistry - paraffin section to investigate mediation by the GAP-related domain in the synergy between loss of NF1 and overexpression of MYCN in neuroblastoma
Wed Apr 27 00:00:00 UTC 2016
Regulation of downstream neuronal genes by proneural transcription factors during initial neurogenesis in the vertebrate brain.
Neural development
Ware M,Hamdi-Rozé H,Le Friec J,David V,Dupé V
A21271 was used in immunohistochemistry - paraffin section to discuss the roles of proneural genes and their effectors during differentiation of the neuronal populations
Wed Dec 07 00:00:00 UTC 2016
High content imaging quantification of multiple in vitro human neurogenesis events after neurotoxin exposure.
BMC pharmacology & toxicology
Wu X,Majumder A,Webb R,Stice SL
A-21271 was used in Immunocytochemistry to test neural active compounds in a human developmental neurotoxicity model that represents neural tube stages of vulnerability.
Thu Dec 01 00:00:00 UTC 2016
A new role of hindbrain boundaries as pools of neural stem/progenitor cells regulated by Sox2.
BMC biology
Peretz Y,Eren N,Kohl A,Hen G,Yaniv K,Weisinger K,Cinnamon Y,Sela-Donenfeld D
A-21271 was used in immunohistochemistry - frozen section to assess pools of neural stem/progenitor cells regulated by Sox2 and the novel role of hindbrain boundaries
Fri Jul 08 00:00:00 UTC 2016
Mapping of brain lipid binding protein (Blbp) in the brain of adult zebrafish, co-expression with aromatase B and links with proliferation.
Gene expression patterns : GEP
Diotel N,Vaillant C,Kah O,Pellegrini E
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to provide detailed characterization of Blbp in the entire brain and open up a broad field of research investigating the role of omega-3 polyunsaturated fatty acids in neural stem cell activity in fish.
Fri Jan 01 00:00:00 UTC 2016
Geminin prevents DNA damage in vagal neural crest cells to ensure normal enteric neurogenesis.
BMC biology
Konstantinidou C,Taraviras S,Pachnis V
A21271 was used in immunocytochemistry to discuss factors that impact the migratory behavior of neural crest cells
Mon Oct 24 00:00:00 UTC 2016
Zbtb20 promotes astrocytogenesis during neocortical development.
Nature communications
Nagao M,Ogata T,Sawada Y,Gotoh Y
A-21271 was used in immunohistochemistry - frozen section to study neocrotical development and promotion of astrocytogenesis by Zbtb20
Tue Mar 22 00:00:00 UTC 2016
Experimental Cancer Cachexia Changes Neuron Numbers and Peptide Levels in the Intestine: Partial Protective Effects after Dietary Supplementation with L-Glutamine.
PloS one
Vicentini GE,Fracaro L,de Souza SR,Martins HA,Guarnier FA,Zanoni JN
A-21271 was used in immunohistochemistry evaluate the effect of dietary l-glutamine on the development of experimental cachexia
Mon Aug 14 00:00:00 UTC 2017
Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells.
Nature communications
Okamoto M,Miyata T,Konno D,Ueda HR,Kasukawa T,Hashimoto M,Matsuzaki F,Kawaguchi A
A-21271 was used in Immunohistochemistry to suggest that the timing mechanisms controlling apical progenitors temporal identity function independently of cell-cycle progression and Notch activation mode.
Wed Apr 20 00:00:00 UTC 2016
Active immunization against vasoactive intestinal polypeptide decreases neuronal recruitment and inhibits reproduction in zebra finches.
The Journal of comparative neurology
Vistoropsky Y,Heiblum R,Smorodinsky NI,Barnea A
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to suggest that VIP has a direct positive role in neuronal recruitment and reproduction in birds.
Mon Aug 15 00:00:00 UTC 2016
Modulating the expression level of secreted Wnt3 influences cerebellum development in zebrafish transgenics.
Development (Cambridge, England)
Teh C,Sun G,Shen H,Korzh V,Wohland T
A-21271 was used in Immunohistochemistry to highlight the importance of membrane-localized and secreted Wnt3 during cerebellum development.
Sun Nov 01 00:00:00 UTC 2015
The small leucine-rich repeat secreted protein Asporin induces eyes in Xenopus embryos through the IGF signalling pathway.
Development (Cambridge, England)
Luehders K,Sasai N,Davaapil H,Kurosawa-Yoshida M,Hiura H,Brah T,Ohnuma S
A-21271 was used in immunohistochemistry to examine the role of asporin in the early stages of eye development in Xenopus embryos.
Thu Oct 01 00:00:00 UTC 2015
A Serotonin Circuit Acts as an Environmental Sensor to Mediate Midline Axon Crossing through EphrinB2.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Xing L,Son JH,Stevenson TJ,Lillesaar C,Bally-Cuif L,Dahl T,Bonkowsky JL
A-21271 was used in Immunohistochemistry to demonstrate that vertebrate CNS can modulate its connectivity in response to the developmental environment through serotonergic signaling.
Wed Nov 04 00:00:00 UTC 2015
Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hernández VM,Hegeman DJ,Cui Q,Kelver DA,Fiske MP,Glajch KE,Pitt JE,Huang TY,Justice NJ,Chan CS
A-21271 was used in Immunohistochemistry-floating tissue to characterise distinct neuron classes in the mouse external globus pallidus.
Wed Aug 26 00:00:00 UTC 2015
Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Abdi A,Mallet N,Mohamed FY,Sharott A,Dodson PD,Nakamura KC,Suri S,Avery SV,Larvin JT,Garas FN,Garas SN,Vinciati F,Morin S,Bezard E,Baufreton J,Magill PJ
A-21271 was used in immunohistochemistry - free floating to study prototypic and arkypallidal neurons in dopamine-intact rats
Wed Apr 29 00:00:00 UTC 2015
Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Mao H,Pilaz LJ,McMahon JJ,Golzio C,Wu D,Shi L,Katsanis N,Silver DL
A-21271 was used in immunocytochemistry to examine the role of q2. genes in neurogenesis.
Wed May 06 00:00:00 UTC 2015
CTNND2-a candidate gene for reading problems and mild intellectual disability.
Journal of medical genetics
Hofmeister W,Nilsson D,Topa A,Anderlid BM,Darki F,Matsson H,Tapia Páez I,Klingberg T,Samuelsson L,Wirta V,Vezzi F,Kere J,Nordenskjöld M,Syk Lundberg E,Lindstrand A
A-21271 was used in immunohistochemistry (paraffin) to discuss cytogenetically visible chromosomal translocations.
Sun Feb 01 00:00:00 UTC 2015
Depletion of the IKBKAP ortholog in zebrafish leads to hirschsprung disease-like phenotype.
World journal of gastroenterology
Cheng WW,Tang CS,Gui HS,So MT,Lui VC,Tam PK,Garcia-Barcelo MM
A-21271 was used in immunohistochemistry to determine role of IKBKAP in the development of enteric nervous system and Hirschsprung disease
Sat Feb 21 00:00:00 UTC 2015
Brain-derived neurotrophic factor modulates angiotensin signaling in the hypothalamus to increase blood pressure in rats.
American journal of physiology. Heart and circulatory physiology
Erdos B,Backes I,McCowan ML,Hayward LF,Scheuer DA
A-21271 was used in immunohistochemistry to test if brain-derived neurotrophic factor in the paraventricular nucleus of the hypothalamus contributes to increases in blood pressure
Sun Mar 15 00:00:00 UTC 2015
Prolonged high fat diet ingestion, obesity, and type 2 diabetes symptoms correlate with phenotypic plasticity in myenteric neurons and nerve damage in the mouse duodenum.
Cell and tissue research
Stenkamp-Strahm CM,Nyavor YE,Kappmeyer AJ,Horton S,Gericke M,Balemba OB
A-21271 was used in immunohistochemistry (frozen) to characterize the long term effects of diabetic enteric neuropathy using mouse models.
Sat Aug 01 00:00:00 UTC 2015
Enteric glial cells are associated with stress-induced colonic hyper-contraction in maternally separated rats.
Neurogastroenterology and motility
Fujikawa Y,Tominaga K,Tanaka F,Tanigawa T,Watanabe T,Fujiwara Y,Arakawa T
A-21271 was used in immunohistochemistry to study structural and functional alterations in colonic enteric glial cells in an irritable bowel syndrome model.
Wed Jul 01 00:00:00 UTC 2015
Doublecortin is widely expressed in the developing and adult retina of sharks.
Experimental eye research
Sánchez-Farías N,Candal E
A-21271 was used in immunohistochemistry - paraffin section to investigate the role of doublecortin during neurogenesis using fishes
Fri May 01 00:00:00 UTC 2015
Developmental changes in the flotillin-1 expression pattern of the rat visual cortex.
Neuroscience
Nakadate K
A-21271 was used in immunohistochemistry to study the localization of flotillin-1 in the rat visual cortex during development
Thu Apr 30 00:00:00 UTC 2015
Wnt/ß-catenin signaling is required for radial glial neurogenesis following spinal cord injury.
Developmental biology
Briona LK,Poulain FE,Mosimann C,Dorsky RI
A-21271 was used in immunohistochemistry to investigate the role of Wnt/Beta-catenin signaling in spinal cord regeneration
Wed Jul 01 00:00:00 UTC 2015
Intrinsic and extrinsic innervation of the heart in zebrafish (Danio rerio).
The Journal of comparative neurology
Stoyek MR,Croll RP,Smith FM
A-21271 was used in immunohistochemistry to elucidate the innervation of the heart using zebrafish.
Sat Aug 01 00:00:00 UTC 2015
Expression of Cocaine and Amphetamine Regulated Transcript (CART) in the Porcine Intramural Neurons of Stomach in the Course of Experimentally Induced Diabetes Mellitus.
Journal of molecular neuroscience : MN
Bulc M,Gonkowski S,Całka J
A-21271 was used in immunohistochemistry to test the effect of streptozotocin-induced diabetes on the cocaine- and amphetamine-regulated transcript-like immunoreactive enteric nervous structures.
Sun Nov 01 00:00:00 UTC 2015
Evolutionary Conservation of the Early Axon Scaffold in the Vertebrate Brain.
Developmental dynamics : an official publication of the American Association of Anatomists
Ware M,Dupé V,Schubert FR
A-21271 was used in Immunohistochemistry-immunofluorescence to study the evolutionary conservation of the early axon scaffold in the vertebrate brain.
Thu Oct 01 00:00:00 UTC 2015
Evolutionary Conservation of the Early Axon Scaffold in the Vertebrate Brain.
Developmental dynamics : an official publication of the American Association of Anatomists
Ware M,Dupé V,Schubert FR
A-21271 was used in Immunohistochemistry-immunofluorescence to study the evolutionary conservation of the early axon scaffold in the vertebrate brain.
Thu Oct 01 00:00:00 UTC 2015
Evolutionary Conservation of the Early Axon Scaffold in the Vertebrate Brain.
Developmental dynamics : an official publication of the American Association of Anatomists
Ware M,Dupé V,Schubert FR
A-21271 was used in Immunohistochemistry-immunofluorescence to study the evolutionary conservation of the early axon scaffold in the vertebrate brain.
Thu Oct 01 00:00:00 UTC 2015
Evolutionary Conservation of the Early Axon Scaffold in the Vertebrate Brain.
Developmental dynamics : an official publication of the American Association of Anatomists
Ware M,Dupé V,Schubert FR
A-21271 was used in Immunohistochemistry-immunofluorescence to study the evolutionary conservation of the early axon scaffold in the vertebrate brain.
Thu Oct 01 00:00:00 UTC 2015
Excitatory and inhibitory enteric innervation of horse lower esophageal sphincter.
Histochemistry and cell biology
Chiocchetti R,Giancola F,Mazzoni M,Sorteni C,Romagnoli N,Pietra M
A-21271 was used in immunohistochemistry to study the lower esophageal sphincter of horses.
Mon Jun 01 00:00:00 UTC 2015
Luteinizing hormone receptors are expressed in rat myenteric neurons and mediate neuronal loss.
Autonomic neuroscience : basic & clinical
Sand E,Voss U,Ohlsson B,Ekblad E
A-21271 was used in immunocytochemistry to study the luteinizing hormone receptor in rat myenteric neurons.
Tue Dec 01 00:00:00 UTC 2015
Architecture and Chemical Coding of the Inner and Outer Submucous Plexus in the Colon of Piglets.
PloS one
Petto C,Gäbel G,Pfannkuche H
A-21271 was used in immunohistochemistry to determine the expression and co-localization of different neurotransmitters and neuronal markers in the inner submucous plexus, the outer submucous plexus and neuronal fibers
Fri May 06 00:00:00 UTC 2016
Human Embryonic Stem Cell-Derived Progenitors Assist Functional Sensory Axon Regeneration after Dorsal Root Avulsion Injury.
Scientific reports
Hoeber J,Trolle C,Konig N,Du Z,Gallo A,Hermans E,Aldskogius H,Shortland P,Zhang SC,Deumens R,Kozlova EN
A-21271 was used in immunohistochemistry to assess dorsal root avulsion injury and how human embryonic stem cell-derived progenitors assist functional sensory axo regeneration
Mon Jun 08 00:00:00 UTC 2015
A Branching Process to Characterize the Dynamics of Stem Cell Differentiation.
Scientific reports
Míguez DG
A-21271 was used in immunohistochemistry to create a mathematical model that predicts the average rates of proliferative and differentiative divisions in stem cell population
Wed Aug 19 00:00:00 UTC 2015
Disruptive CHD8 mutations define a subtype of autism early in development.
Cell
Bernier R,Golzio C,Xiong B,Stessman HA,Coe BP,Penn O,Witherspoon K,Gerdts J,Baker C,Vulto-van Silfhout AT,Schuurs-Hoeijmakers JH,Fichera M,Bosco P,Buono S,Alberti A,Failla P,Peeters H,Steyaert J,Vissers LELM,Francescatto L,Mefford HC,Rosenfeld JA,Bakken T,O'Roak BJ,Pawlus M,Moon R,Shendure J,Amaral DG,Lein E,Rankin J,Romano C,de Vries BBA,Katsanis N,Eichler EE
A-21271 was used in immunocytochemistry to identify CHD8 disruptions in a distinct autism spectrum disorder subtype and reveal comorbidities between brain development and enteric innervation
Thu Jul 17 00:00:00 UTC 2014
Deletion of the von Hippel-Lindau gene causes sympathoadrenal cell death and impairs chemoreceptor-mediated adaptation to hypoxia.
EMBO molecular medicine
Macías D,Fernández-Agüera MC,Bonilla-Henao V,López-Barneo J
A-21271 was used in immunohistochemistry - paraffin section to examine the contribution of the von Hippel-Lindau gene to sympathoadrenal homeostasis
Mon Dec 01 00:00:00 UTC 2014
Mutations in QARS, encoding glutaminyl-tRNA synthetase, cause progressive microcephaly, cerebral-cerebellar atrophy, and intractable seizures.
American journal of human genetics
Zhang X,Ling J,Barcia G,Jing L,Wu J,Barry BJ,Mochida GH,Hill RS,Weimer JM,Stein Q,Poduri A,Partlow JN,Ville D,Dulac O,Yu TW,Lam AT,Servattalab S,Rodriguez J,Boddaert N,Munnich A,Colleaux L,Zon LI,Söll D,Walsh CA,Nabbout R
A-21271 was used in immunocytochemistry to identify QARS (encoding glutaminyl-tRNA synthetase [QARS]) mutations in two unrelated families affected by progressive microcephaly
Thu Apr 03 00:00:00 UTC 2014
Ewing sarcoma of the small bowel: a study of seven cases, including one with the uncommonly reported EWSR1-FEV translocation.
Histopathology
Milione M,Gasparini P,Sozzi G,Mazzaferro V,Ferrari A,Casali PG,Perrone F,Tamborini E,Pellegrinelli A,Gherardi G,Arrigoni G,Collini P,Testi A,De Paoli E,Aiello A,Pilotti S,Pelosi G
A-21271 was used in immunohistochemistry to discuss Ewing sarcoma.
Sun Jun 01 00:00:00 UTC 2014
An increase in MECP2 dosage impairs neural tube formation.
Neurobiology of disease
Petazzi P,Akizu N,García A,Estarás C,Martínez de Paz A,Rodríguez-Paredes M,Martínez-Balbás MA,Huertas D,Esteller M
A-21271 was used in immunocytochemistry to study the effects of increased MECP2 on development of the nervous system
Tue Jul 01 00:00:00 UTC 2014
Exclusive multipotency and preferential asymmetric divisions in post-embryonic neural stem cells of the fish retina.
Development (Cambridge, England)
Centanin L,Ander JJ,Hoeckendorf B,Lust K,Kellner T,Kraemer I,Urbany C,Hasel E,Harris WA,Simons BD,Wittbrodt J
A-21271 was used in immunocytochemistry to develop a clonal labeling and non-invasive fate tracking system and study post-embryonic stem cells in the retina
Mon Sep 01 00:00:00 UTC 2014
Activated retinoid receptors are required for the migration and fate maintenance of subsets of cortical neurons.
Development (Cambridge, England)
Choi J,Park S,Sockanathan S
A-21271 was used in Immunohistochemistry-immunofluorescence to suggest that retinoic acid signalling pathways operate postmitotically to regulate radial migration and consolidate regional differences in cortical neuronal identity.
Sat Mar 01 00:00:00 UTC 2014
Radial glial progenitors repair the zebrafish spinal cord following transection.
Experimental neurology
Briona LK,Dorsky RI
A-21271 was used in immunohistochemistry - frozen section to investigate the role of Dbx1 in neurogenesis in zebrafish
Sun Jun 01 00:00:00 UTC 2014
Induced pluripotency in chicken embryonic fibroblast results in a germ cell fate.
Stem cells and development
Lu Y,West FD,Jordan BJ,Jordan ET,West RC,Yu P,He Y,Barrios MA,Zhu Z,Petitte JN,Beckstead RB,Stice SL
A-21271 was used in immunocytochemistry to study the mechanisms that regulate the acquisition and maintenance germ cell character
Fri Aug 01 00:00:00 UTC 2014
Human enteric neurons: morphological, electrophysiological, and neurochemical identification.
Neurogastroenterology and motility
Carbone SE,Jovanovska V,Nurgali K,Brookes SJ
A-21271 was used in immunohistochemistry to describe a method to study neurons in the intact myenteric plexus of human colon ex vivo.
Mon Dec 01 00:00:00 UTC 2014
Oestradiol and diet modulate energy homeostasis and hypothalamic neurogenesis in the adult female mouse.
Journal of neuroendocrinology
Bless EP,Reddy T,Acharya KD,Beltz BS,Tetel MJ
A-21271 was used in immunohistochemistry - frozen section to test if diet and hormonal status modulate hypothalamic neurogenesis in the adult female mouse
Sat Nov 01 00:00:00 UTC 2014
Developmental, tract-tracing and immunohistochemical study of the peripheral olfactory system in a basal vertebrate: insights on Pax6 neurons migrating along the olfactory nerve.
Brain structure & function
Quintana-Urzainqui I,Rodríguez-Moldes I,Candal E
A-21271 was used in immunohistochemistry - paraffin section to study the development of the olfactory system in Scyliorhinus canicula
Wed Jan 01 00:00:00 UTC 2014
Estradiol treatment decreases cell proliferation in the neurogenic zones of adult female zebrafish (Danio rerio) brain.
Neuroscience
Makantasi P,Dermon CR
A-21271 was used in immunohistochemistry to determine the effects pf estrogen in adult brain proliferation zones
Fri Sep 26 00:00:00 UTC 2014
Cell death, cavitation and spontaneous multi-differentiation of dental pulp stem cells-derived spheroids in vitro: a journey to survival and organogenesis.
Biology of the cell
Xiao L,Kumazawa Y,Okamura H
A-21271 was used in immunohistochemistry to examine cavitation and differentiation of human dental pulp stem cells
Mon Dec 01 00:00:00 UTC 2014
Age-related changes in stem cell dynamics, neurogenesis, apoptosis, and gliosis in the adult brain: a novel teleost fish model of negligible senescence.
Developmental neurobiology
Traniello IM,Sîrbulescu RF,Ilieş I,Zupanc GK
A-21271 was used in immunohistochemistry to assess the age-related changes associated with adult neurogenesis in the brain of brown ghost knifefish.
Thu May 01 00:00:00 UTC 2014
Regulation of later neurogenic stages of adult-derived neural stem/progenitor cells by L-type Ca2+ channels.
Development, growth & differentiation
Teh DB,Ishizuka T,Yawo H
A-21271 was used in immunocytochemistry to determine which stage of neurogenesis is under the regulation of L-type Ca2+ channels.
Wed Oct 01 00:00:00 UTC 2014
Regional innervation of the heart in the goldfish, Carassius auratus: a confocal microscopy study.
The Journal of comparative neurology
Newton CM,Stoyek MR,Croll RP,Smith FM
A-21271 was used in immunohistochemistry to report the innervation patterns in the heart of the goldfish.
Sat Feb 01 00:00:00 UTC 2014
Parcellation of cerebellins 1, 2, and 4 among different subpopulations of dorsal horn neurons in mouse spinal cord.
The Journal of comparative neurology
Cagle MC,Honig MG
A-21271 was used in immunohistochemistry to study the function of cerebellins in the cerebellum and striatum
Sat Feb 01 00:00:00 UTC 2014
Development of the cerebellar afferent system in the shark Scyliorhinus canicula: insights into the basal organization of precerebellar nuclei in gnathostomes.
The Journal of comparative neurology
Pose-Méndez S,Candal E,Adrio F,Rodríguez-Moldes I
A-21271 was used in immunohistochemistry to study the cerebellar connections in shark embryos and juveniles
Wed Jan 01 00:00:00 UTC 2014
DCX-expressing cells in the vicinity of the hypothalamic neurogenic niche: a comparative study between mouse, sheep, and human tissues.
The Journal of comparative neurology
Batailler M,Droguerre M,Baroncini M,Fontaine C,Prevot V,Migaud M
A-21271 was used in immunohistochemistry - frozen section to study the expression of the neuroblast marker doublecortin in adult ovine, mouse, and human hypothalamic tissues.
Sun Jun 01 00:00:00 UTC 2014
PTEN inhibition enhances neurite outgrowth in human embryonic stem cell-derived neuronal progenitor cells.
The Journal of comparative neurology
Wyatt LA,Filbin MT,Keirstead HS
A-21271 was used in immunocytochemistry to study the role of PTEN in neurite outgrowth in human embryonic stem cell-derived neuronal progenitor cells
Fri Aug 15 00:00:00 UTC 2014
Piezo2 expression in corneal afferent neurons.
The Journal of comparative neurology
Bron R,Wood RJ,Brock JA,Ivanusic JJ
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to provide the first evidence in an in vivo system that Piezo2 is a strong candidate for a channel that transduces noxious mechanical stimuli.
Mon Sep 01 00:00:00 UTC 2014
Spatiotemporal distribution of SUMOylation components during mouse brain development.
The Journal of comparative neurology
Hasegawa Y,Yoshida D,Nakamura Y,Sakakibara S
A-21271 was used in immunohistochemistry to profile SUMOylation components during mouse brain development.
Mon Sep 01 00:00:00 UTC 2014
Characterization of a novel primary culture system of adult zebrafish brainstem cells.
Journal of neuroscience methods
Tapanes-Castillo A,Shabazz FS,Mboge MY,Vajn K,Oudega M,Plunkett JA
A-21271 was used in immunocytochemistry to describe a brainstem culture model to study axonal growth, neurogenesis, and regeneration of the adult zebrafish central nervous system.
Sat Feb 15 00:00:00 UTC 2014
Large-scale identification of proteins involved in the development of a sexually dimorphic behavior.
Journal of neurophysiology
Zupanc GK,Ilies I,Sîrbulescu RF,Zupanc MM
A-21271 was used in immunohistochemistry (frozen) to identify proteins involved in the development of a sexually dimorphic behavior using the brown ghost knifefish.
Tue Apr 01 00:00:00 UTC 2014
Enteric neuroplasticity in seawater-adapted European eel (Anguilla anguilla).
Journal of anatomy
Sorteni C,Clavenzani P,De Giorgio R,Portnoy O,Sirri R,Mordenti O,Di Biase A,Parmeggiani A,Menconi V,Chiocchetti R
A-21271 was used in immunohistochemistry (frozen) to use European eels to understand the adaptive changes of the enteric nervous system to modified salinity and starvation.
Sat Feb 01 00:00:00 UTC 2014
Proteinase-activated receptor 2 expression in the intestinal tract of the horse.
Research in veterinary science
Zannoni A,Bombardi C,Dondi F,Morini M,Forni M,Chiocchetti R,Spadari A,Romagnoli N
A-21271 was used in immunohistochemistry to study the equine intestinal expression of PAR2.
Sun Jun 01 00:00:00 UTC 2014
Directing mouse embryonic neurosphere differentiation toward an enriched neuronal population.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience
Torrado EF,Gomes C,Santos G,Fernandes A,Brites D,Falcão AS
A-21271 was used in immunocytochemistry to describe the development a neurosphere culture method that results in highly proliferative stem/progenitor cell population
Wed Oct 01 00:00:00 UTC 2014
Co-expression patterns of cocaine- and amphetamine-regulated transcript (CART) with neuropeptides in dorsal root ganglia of the pig.
Acta histochemica
Zacharko-Siembida A,Kulik P,Szalak R,Lalak R,Arciszewski MB
A-21271 was used in immunohistochemistry - frozen section to determine the neuronal distribution of CART in porcine dorsal root ganglia
Sat Mar 01 00:00:00 UTC 2014
Differential responsiveness of distinct retinal domains to Atoh7.
Mechanisms of development
Sinn R,Peravali R,Heermann S,Wittbrodt J
A-21271 was used in immunohistochemistry to explore the differential susceptibilities of early retinal progenitor cells to Atoh7 in vivo
Fri Aug 01 00:00:00 UTC 2014
Immunoreactivity to cocaine- and amphetamine-regulated transcript in the enteric nervous system of the pig and wild boar stomach.
Anatomia, histologia, embryologia
Zacharko-Siembida A,Arciszewski MB
A-21271 was used in immunohistochemistry - frozen section to study the distribution patterns of cocaine- and amphetamine-regulated transcript in the stomach of the pig and wild boar
Sat Feb 01 00:00:00 UTC 2014
Sustained Wnt/β-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole.
Nature communications
Herrera A,Saade M,Menendez A,Marti E,Pons S
A-21271 was used in immunohistochemistry to report that beta-catenin controls the cell fate and polarity of neuroblasts by modulating the expression and localization of aPKC.
Thu Jun 19 00:00:00 UTC 2014
Abnormal neurons in teratomas in NMDAR encephalitis.
JAMA neurology
Day GS,Laiq S,Tang-Wai DF,Munoz DG
A-21271 was used in Immunohistochemistry to characterize the unique organization of neuroglial elements within ovarian teratomas resected from patients with NMDAR encephalitis.
Sun Jun 01 00:00:00 UTC 2014
De novo SOX11 mutations cause Coffin-Siris syndrome.
Nature communications
Tsurusaki Y,Koshimizu E,Ohashi H,Phadke S,Kou I,Shiina M,Suzuki T,Okamoto N,Imamura S,Yamashita M,Watanabe S,Yoshiura K,Kodera H,Miyatake S,Nakashima M,Saitsu H,Ogata K,Ikegawa S,Miyake N,Matsumoto N
A-21271 was used in immunohistochemistry to investigate the impact of the BAF complex and SOX11 transcriptional network in brain development.
Mon Jun 02 00:00:00 UTC 2014
Two cases of multinodular and vacuolating neuronal tumour.
Acta neuropathologica communications
Bodi I,Curran O,Selway R,Elwes R,Burrone J,Laxton R,Al-Sarraj S,Honavar M
A-21271 was used in immunohistochemistry (paraffin) to characterize two patients with multinodular and vacuolating neuronal tumors.
Mon Jan 20 00:00:00 UTC 2014
Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis.
Cell reports
Hori K,Nagai T,Shan W,Sakamoto A,Taya S,Hashimoto R,Hayashi T,Abe M,Yamazaki M,Nakao K,Nishioka T,Sakimura K,Yamada K,Kaibuchi K,Hoshino M
A-21271 was used in Immunohistochemistry to demonstrate a role for cytoplasmic AUTS2 in the regulation of Rho family GTPases contributing to neural development.
Wed Dec 24 00:00:00 UTC 2014
A method for exploring adult neurogenesis in the songbird brain.
Cold Spring Harbor protocols
Asik K,Rao JL,Kirn JR
A-21271 was used in immunohistochemistry to describe a method to study adult neurogenesis using avian brains
Thu Oct 23 00:00:00 UTC 2014
BMP signaling in astrocytes downregulates EGFR to modulate survival and maturation.
PloS one
Scholze AR,Foo LC,Mulinyawe S,Barres BA
A-21271 was used in immunocytochemistry to show that fibroblast growth factors and bone morphogenetic proteins contribute to astrocyte development
Tue Dec 22 00:00:00 UTC 2015
Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish.
Scientific reports
Shi Y,Zhang Y,Zhao F,Ruan H,Huang H,Luo L,Li L
A-21271 was used in immunocytochemistry to establish a model to study the effects of opioids on the gut development and peristalsis using zebrafish
Mon Jul 07 00:00:00 UTC 2014
Hirschsprung-like disease is exacerbated by reduced de novo GMP synthesis.
The Journal of clinical investigation
Lake JI,Tusheva OA,Graham BL,Heuckeroth RO
A-21271 was used in immunohistochemistry to test if nongenetic factors might contribute to Hirschsprung disease using a zebrafish model.
Fri Nov 01 00:00:00 UTC 2013
A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation.
Brain : a journal of neurology
Mahmood F,Fu S,Cooke J,Wilson SW,Cooper JD,Russell C
A-21271 was used in Immunohistochemistry-immunofluorescence to provide proof-of-principle that tpp1(sa0011)(-/-) mutants can utilize the advantages of zebrafish for understanding pathogenesis and drug discovery in CLN2 disease.
Wed May 01 00:00:00 UTC 2013
Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus.
American journal of human genetics
Beunders G,Voorhoeve E,Golzio C,Pardo LM,Rosenfeld JA,Talkowski ME,Simonic I,Lionel AC,Vergult S,Pyatt RE,van de Kamp J,Nieuwint A,Weiss MM,Rizzu P,Verwer LE,van Spaendonk RM,Shen Y,Wu BL,Yu T,Yu Y,Chiang C,Gusella JF,Lindgren AM,Morton CC,van Binsbergen E,Bulk S,van Rossem E,Vanakker O,Armstrong R,Park SM,Greenhalgh L,Maye U,Neill NJ,Abbott KM,Sell S,Ladda R,Farber DM,Bader PI,Cushing T,Drautz JM,Konczal L,Nash P,de Los Reyes E,Carter MT,Hopkins E,Marshall CR,Osborne LR,Gripp KW,Thrush DL,Hashimoto S,Gastier-Foster JM,Astbury C,Ylstra B,Meijers-Heijboer H,Posthuma D,Menten B,Mortier G,Scherer SW,Eichler EE,Girirajan S,Katsanis N,Groffen AJ,Sistermans EA
A-21271 was used in immunohistochemistry to show a causal role of AUTS2 in neurocognitive disorders.
Thu Feb 07 00:00:00 UTC 2013
An inducible transgene expression system for zebrafish and chick.
Development (Cambridge, England)
Gerety SS,Breau MA,Sasai N,Xu Q,Briscoe J,Wilkinson DG
A-21271 was used in immunohistochemistry to develop an inducible system to control the timing of transgene expression in zebrafish and chicks.
Wed May 01 00:00:00 UTC 2013
Modulation of dorsal root ganglion development by ErbB signaling and the scaffold protein Sorbs3.
Development (Cambridge, England)
Malmquist SJ,Abramsson A,McGraw HF,Linbo TH,Raible DW
A-21271 was used in Immunohistochemistry to propose a model in which Sorbs3 helps to integrate ErbB signals to promote DRG neurogenesis through the activation of MAPK and upregulation of neurogenin1.
Tue Oct 01 00:00:00 UTC 2013
Cell delamination in the mesencephalic neural fold and its implication for the origin of ectomesenchyme.
Development (Cambridge, England)
Lee RT,Nagai H,Nakaya Y,Sheng G,Trainor PA,Weston JA,Thiery JP
A-21271 was used in immunohistochemistry (frozen) to investigate what defines the neural crest and the origin of the ectomesenchyme in mice and chickens.
Sun Dec 01 00:00:00 UTC 2013
Indian hedgehog B function is required for the specification of oligodendrocyte progenitor cells in the zebrafish CNS.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Chung AY,Kim S,Kim E,Kim D,Jeong I,Cha YR,Bae YK,Park SW,Lee J,Park HC
A-21271 was used in immunohistochemistry to study the generation of motor neurons and oligodendrocytes.
Wed Jan 23 00:00:00 UTC 2013
Smad2 and Smad3 cooperate and antagonize simultaneously in vertebrate neurogenesis.
Journal of cell science
Míguez DG,Gil-Guiñón E,Pons S,Martí E
A-21271 was used in immunohistochemistry to elucidate the role of transforming growth factor beta during neurogenesis.
Sun Dec 01 00:00:00 UTC 2013
MicroRNA 22 regulates cell cycle length in cerebellar granular neuron precursors.
Molecular and cellular biology
Berenguer J,Herrera A,Vuolo L,Torroba B,Llorens F,Sumoy L,Pons S
A-21271 was used in immunocytochemistry to elucidate the BMP antimitotic mechanism.
Mon Jul 01 00:00:00 UTC 2013
Mast cell expression of the serotonin1A receptor in guinea pig and human intestine.
American journal of physiology. Gastrointestinal and liver physiology
Wang GD,Wang XY,Zou F,Qu M,Liu S,Fei G,Xia Y,Needleman BJ,Mikami DJ,Wood JD
A-21271 was used in immunohistochemistry to study the role of serotonin on enteric mast cells.
Wed May 15 00:00:00 UTC 2013
Characterization of human dental pulp cells-derived spheroids in serum-free medium: stem cells in the core.
Journal of cellular biochemistry
Xiao L,Tsutsui T
A-21271 was used in immunohistochemistry - paraffin section to study the dynamics, cell distribution, molecular profiles, and neuronal/osteogenic potential of spheroids generated from human dental pulp.
Fri Nov 01 00:00:00 UTC 2013
Intracerebral transplantation of differentiated human embryonic stem cells to hemiparkinsonian monkeys.
Cell transplantation
Emborg ME,Zhang Z,Joers V,Brunner K,Bondarenko V,Ohshima S,Zhang SC
A-21271 was used in immunohistochemistry to assess the use of stem cell therapy for Parkinson's disease using rhesus monkeys.
Mon Dec 23 00:00:00 UTC 2013
High-fat diet ingestion correlates with neuropathy in the duodenum myenteric plexus of obese mice with symptoms of type 2 diabetes.
Cell and tissue research
Stenkamp-Strahm CM,Kappmeyer AJ,Schmalz JT,Gericke M,Balemba O
A-21271 was used in Immunohistochemistry to correlate high-fat diet ingestion, obesity and type 2 diabetes symptoms with a loss of duodenal neurons.
Fri Nov 01 00:00:00 UTC 2013
Myenteric neuron numbers are maintained in aging mouse distal colon.
Neurogastroenterology and motility
Gamage PP,Ranson RN,Patel BA,Yeoman MS,Saffrey MJ
A-21271 was used in immunocytochemistry to examine neurons in the mouse distal colon during aging.
Mon Jul 01 00:00:00 UTC 2013
Sexually dimorphic and developmentally regulated expression of tubulin-specific chaperone protein A in the LMAN of zebra finches.
Neuroscience
Qi LM,Wade J
A-21271 was used in immunocytochemistry to test if the Z-gene contributes to sexual differentiation of the song system.
Thu Sep 05 00:00:00 UTC 2013
Dner inhibits neural progenitor proliferation and induces neuronal and glial differentiation in zebrafish.
Developmental biology
Hsieh FY,Ma TL,Shih HY,Lin SJ,Huang CW,Wang HY,Cheng YC
A-21271 was used in immunohistochemistry to investigate the role of Delta/notch-like epidermal growth factor-related receptor in the developing Drosophilia nervous system.
Fri Mar 01 00:00:00 UTC 2013
Coexpression of Runx1 and Runx3 in mechanoreceptive dorsal root ganglion neurons.
Developmental neurobiology
Yoshikawa M,Murakami Y,Senzaki K,Masuda T,Ozaki S,Ito Y,Shiga T
A-21271 was used in immunohistochemistry - frozen section to examine the expression of Runx and Runx3 in the mouse dorsal root ganglion during embryonic and postnatal development.
Sat Jun 01 00:00:00 UTC 2013
Expression of β2 adrenoceptors within enteric neurons of the horse ileum.
Research in veterinary science
Bombardi C,Grandis A,Gardini A,Sorteni C,Clavenzani P,Chiocchetti R
A-21271 was used in immunohistochemistry (frozen) to study adrenergic receptors in the horse intestine.
Sun Dec 01 00:00:00 UTC 2013
Neurochemistry of myenteric plexus neurons of bank vole (Myodes glareolus) ileum.
Research in veterinary science
Sadeghinezhad J,Sorteni C,Di Guardo G,D'Agostino C,Agrimi U,Nonno R,Chiocchetti R
A-21271 was used in immunohistochemistry to describe the phenotype of ileal myenteric plexus neuronal cells and fibers of the bank vole.
Sun Dec 01 00:00:00 UTC 2013
High-fat diet and age-dependent effects on enteric glial cell populations of mouse small intestine.
Autonomic neuroscience : basic & clinical
Stenkamp-Strahm C,Patterson S,Boren J,Gericke M,Balemba O
A-21271 was used in immunohistochemistry to report that mucosal glia cell damage occurs during diabetic symptoms.
Tue Oct 01 00:00:00 UTC 2013
Characterization of enteric neurons in wild-type and mutant zebrafish using semi-automated cell counting and co-expression analysis.
Zebrafish
Simonson LW,Ganz J,Melancon E,Eisen JS
A-21271 was used in immunohistochemistry to develop tools to study fluorescent enteric neurons in zebrafish.
Sat Jun 01 00:00:00 UTC 2013
Immunolocalization of NOS, VIP, galanin and SP in the small intestine of suckling pigs treated with red kidney bean (Phaseolus vulgaris) lectin.
Acta histochemica
Zacharko-Siembida A,Valverde Piedra JL,Szymańczyk S,Arciszewski MB
A-21271 was used in immunohistochemistry - frozen section to test if treatment with red kidney bean lectin influences the chemical code of the small intestine nervous system of suckling pigs.
Mon Apr 01 00:00:00 UTC 2013
Intrinsic innervation of the Persian squirrel (Sciurus anomalus) ileum.
Anatomia, histologia, embryologia
Sadeghinezhad J,Tootian Z,Latorre R,Sorteni C,Chiocchetti R
A-21271 was used in immunohistochemistry to study the enteric nervous system of wild or 'unconventional' rodents.
Sat Jun 01 00:00:00 UTC 2013
Changes in expression of calbindin 28 kDa in the small intestine of red kidney bean (Phaseolus vulgaris) lectin-treated suckling piglets.
Polish journal of veterinary sciences
Zacharko-Siembida A,Piedra JL,Arciszewski MB
A-21271 was used in immunohistochemistry - frozen section to investigate calbindin expression in the pig gastrointestinal tract.
Thu Sep 05 00:00:00 UTC 2013
Zebrafish as a model for monocarboxyl transporter 8-deficiency.
The Journal of biological chemistry
Vatine GD,Zada D,Lerer-Goldshtein T,Tovin A,Malkinson G,Yaniv K,Appelbaum L
A-21271 was used in western blot to show that MCT8 deficient zebrafish exhibit a neurological phenotype.
Fri Jan 04 00:00:00 UTC 2013
Mmp17b is essential for proper neural crest cell migration in vivo.
PloS one
Leigh NR,Schupp MO,Li K,Padmanabhan V,Gastonguay A,Wang L,Chun CZ,Wilkinson GA,Ramchandran R
A-21271 was used in immunohistochemistry to investigate the role of matrix metalloproteinase 17b to neural crest cell migration in zebrafish.
Mon Jul 28 00:00:00 UTC 2014
KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant.
Nature
Golzio C,Willer J,Talkowski ME,Oh EC,Taniguchi Y,Jacquemont S,Reymond A,Sun M,Sawa A,Gusella JF,Kamiya A,Beckmann JS,Katsanis N
A-21271 was used in immunohistochemistry to study the effects of KCTD3 copy number in zebrafish.
Wed May 16 00:00:00 UTC 2012
Stab wound injury of the zebrafish telencephalon: a model for comparative analysis of reactive gliosis.
Glia
Baumgart EV,Barbosa JS,Bally-Cuif L,Götz M,Ninkovic J
A-21271 was used in immunohistochemistry to study glial responses using an invasive stab wound model.
Thu Mar 01 00:00:00 UTC 2012
Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.
Development (Cambridge, England)
Estarás C,Akizu N,García A,Beltrán S,de la Cruz X,Martínez-Balbás MA
A-21271 was used in Immunohistochemistry to indicate that JMJD3 function is required for the TGFΒ developmental program to proceed.
Wed Aug 01 00:00:00 UTC 2012
Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres.
Development (Cambridge, England)
Virolainen SM,Achim K,Peltopuro P,Salminen M,Partanen J
A-21271 was used in immunohistochemistry to study the fate of GABAergic neurons in different diencephalic prosomeres and the transcriptional mechanisms involved.
Mon Oct 01 00:00:00 UTC 2012
Signalling from hindbrain boundaries regulates neuronal clustering that patterns neurogenesis.
Development (Cambridge, England)
Terriente J,Gerety SS,Watanabe-Asaka T,Gonzalez-Quevedo R,Wilkinson DG
A-21271 was used in immunohistochemistry to investigate how fgf20a-expressing neurons in segment centers cluster.
Wed Aug 01 00:00:00 UTC 2012
Antagonistic regulation of PAF1C and p-TEFb is required for oligodendrocyte differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kim S,Kim JD,Chung AY,Kim HS,Kim YS,Kim MJ,Koun S,Lee YM,Rhee M,Park HC,Huh TL
A-21271 was used in immunohistochemistry to elucidate mechanisms underlying oligodendrocyte differentiation.
Wed Jun 13 00:00:00 UTC 2012
Self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated from the cortical peri-infarct area after stroke.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Shimada IS,LeComte MD,Granger JC,Quinlan NJ,Spees JL
A-21271 was used in immunohistochemistry to study the self-renewal and differentiation of reactive astrocyte-derived neural stem/progenitor cells isolated after stroke.
Wed Jun 06 00:00:00 UTC 2012
Wandering neuronal migration in the postnatal vertebrate forebrain.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Scott BB,Gardner T,Ji N,Fee MS,Lois C
A-21271 was used in immunohistochemistry to study how new neurons migrate through the mature brain and integrate.
Wed Jan 25 00:00:00 UTC 2012
Immunohistochemical analysis of myenteric ganglia and interstitial cells of Cajal in ulcerative colitis.
Journal of cellular and molecular medicine
Bernardini N,Segnani C,Ippolito C,De Giorgio R,Colucci R,Faussone-Pellegrini MS,Chiarugi M,Campani D,Castagna M,Mattii L,Blandizzi C,Dolfi A
A-21271 was used in immunohistochemistry to examine the neural-glial components of myenteric ganglia and interstitial cells of Cajal in patients with ulcerative colitis.
Wed Feb 01 00:00:00 UTC 2012
Cell proliferation pattern in adult zebrafish forebrain is sexually dimorphic.
Neuroscience
Ampatzis K,Makantasi P,Dermon CR
A-21271 was used in immunohistochemistry to examine if sex differences in cell proliferation represents a conserved feature of adult brain plasticity.
Thu Dec 13 00:00:00 UTC 2012
MANF regulates dopaminergic neuron development in larval zebrafish.
Developmental biology
Chen YC,Sundvik M,Rozov S,Priyadarshini M,Panula P
A-21271 was used in immunohistochemistry to study the role of MANF during dopaminergic neuron development in larval zebrafish.
Mon Oct 15 00:00:00 UTC 2012
Birth of neural progenitors during the embryonic period of sexual differentiation in the Japanese quail brain.
The Journal of comparative neurology
Bardet SM,Mouriec K,Balthazart J
A-21271 was used in immunohistochemistry to investigate the ontogeny of diencephalic brain nuclei using quail.
Sat Dec 15 00:00:00 UTC 2012
Neuronal and glial differentiation during lizard (Gallotia galloti) visual system ontogeny.
The Journal of comparative neurology
Romero-Alemán MM,Monzón-Mayor M,Santos E,Lang DM,Yanes C
A-21271 was used in immunohistochemistry to study the histogenesis of the lizard visual system.
Sun Jul 01 00:00:00 UTC 2012
Galanin gene expression and effects of its knock-down on the development of the nervous system in larval zebrafish.
The Journal of comparative neurology
Podlasz P,Sallinen V,Chen YC,Kudo H,Fedorowska N,Panula P
A-21271 was used in immunocytochemistry to assess the role of galanin in developing zebrafish.
Sat Dec 01 00:00:00 UTC 2012
olig2-Expressing hindbrain cells are required for migrating facial motor neurons.
Developmental dynamics : an official publication of the American Association of Anatomists
Zannino DA,Sagerström CG,Appel B
A-21271 was used in immunohistochemistry to show that olig2 function contributes to the migration of facial motor neurons.
Wed Feb 01 00:00:00 UTC 2012
Adult neurogenesis in the brain of the Mozambique tilapia, Oreochromis mossambicus.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology
Teles MC,Sîrbulescu RF,Wellbrock UM,Oliveira RF,Zupanc GK
A-21271 was used in immunohistochemistry to study the generation, migration, and differentiation of new neurons and glial cells in the Mozambique tilapia.
Fri Jun 01 00:00:00 UTC 2012
Intestinal dysmotility and enteric neurochemical changes in a Parkinson's disease rat model.
Autonomic neuroscience : basic & clinical
Colucci M,Cervio M,Faniglione M,De Angelis S,Pajoro M,Levandis G,Tassorelli C,Blandini F,Feletti F,De Giorgio R,Dellabianca A,Tonini S,Tonini M
A-21271 was used in immunocytochemistry to investigate mechanisms underlying the enteric neurochemical plasticity events evoked by disruption of the normal brain-gut cross-talk.
Thu Aug 16 00:00:00 UTC 2012
Macrophages associated with the intrinsic and extrinsic autonomic innervation of the rat gastrointestinal tract.
Autonomic neuroscience : basic & clinical
Phillips RJ,Powley TL
A-21271 was used in immunohistochemistry - free floating to study interactions between macrophages and the autonomic innervation of gastrointestinal tract smooth muscle.
Mon Jul 02 00:00:00 UTC 2012
Spinal transection induces widespread proliferation of cells along the length of the spinal cord in a weakly electric fish.
Brain, behavior and evolution
Allen AR,Smith GT
A-21271 was used in immunohistochemistry to assess the proliferation and survival of cells following complete spinal cord transection using teleost fish.
Fri May 17 00:00:00 UTC 2013
Characterization of Na+ and Ca2+ channels in zebrafish dorsal root ganglion neurons.
PloS one
Won YJ,Ono F,Ikeda SR
A-21271 was used in immunohistochemistry - frozen section to compare electrophysiological events in rats and zebrafish.
Thu Jan 10 00:00:00 UTC 2013
Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons.
BMC gastroenterology
Voss U,Sand E,Hellström PM,Ekblad E
A-21271 was used in immunocytochemistry to assess the neuroprotective effects of vasoactive intestinal peptide and glucagon-like peptide and 2.
Sun Apr 01 00:00:00 UTC 2012
Glucagon-like peptide-1 modulates neurally evoked mucosal chloride secretion in guinea pig small intestine in vitro.
American journal of physiology. Gastrointestinal and liver physiology
Baldassano S,Wang GD,Mulè F,Wood JD
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to investigate effects of GLP-1.
Wed Feb 01 00:00:00 UTC 2012
Brain selective transgene expression in zebrafish using an NRSE derived motif.
Frontiers in neural circuits
Bergeron SA,Hannan MC,Codore H,Fero K,Li GH,Moak Z,Yokogawa T,Burgess HA
A-21271 was used in immunohistochemistry to study how to restrict transgene expression to the nervous system in zebrafish larvae.
Tue Jan 08 00:00:00 UTC 2013
Characterization of cell proliferation throughout the brain of the African cichlid fish Astatotilapia burtoni and its regulation by social status.
The Journal of comparative neurology
Maruska KP,Carpenter RE,Fernald RD
A-21271 was used in Immunohistochemistry to analyze the mechanisms of socially induced neurogenesis in vertebrates.
Mon Oct 15 00:00:00 UTC 2012
Zebrafish Mnx proteins specify one motoneuron subtype and suppress acquisition of interneuron characteristics.
Neural development
Seredick SD,Van Ryswyk L,Hutchinson SA,Eisen JS
A-21271 was used in immunohistochemistry to examine the roles of Mnx family transcription factors in specifying the subtypes of individually identified zebrafish primary motoneurons
Mon Nov 05 00:00:00 UTC 2012
CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells.
Nature biotechnology
Sim FJ,McClain CR,Schanz SJ,Protack TL,Windrem MS,Goldman SA
A-21271 was used in Immunocytochemistry-immunoflourescence to establish a more efficient means of isolating myelinogenic oligodendrocyte progenitor cells.
Sun Sep 25 00:00:00 UTC 2011
Vertebrate-specific glutaredoxin is essential for brain development.
Proceedings of the National Academy of Sciences of the United States of America
Bräutigam L,Schütte LD,Godoy JR,Prozorovski T,Gellert M,Hauptmann G,Holmgren A,Lillig CH,Berndt C
A-21271 was used in immunohistochemistry to report that embryonic brain development depends on glutaredoxin 2 activity.
Tue Dec 20 00:00:00 UTC 2011
Paraneoplastic upbeat nystagmus.
Neurology
Wray SH,Martinez-Hernandez E,Dalmau J,Maheshwari A,Chen A,King S,Bishop Pitman M,Leigh RJ
A-21271 was used in immunohistochemistry to discuss paraneoplastic upbeat nystagmus.
Tue Aug 16 00:00:00 UTC 2011
Defective neuroepithelial cell cohesion affects tangential branchiomotor neuron migration in the zebrafish neural tube.
Development (Cambridge, England)
Stockinger P,Maître JL,Heisenberg CP
A-21271 was used in immunohistochemistry to determine the role of neuroepithelial cells cohesion in facial branchiomotor neuron migration.
Tue Nov 01 00:00:00 UTC 2011
Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors.
Development (Cambridge, England)
Kroehne V,Freudenreich D,Hans S,Kaslin J,Brand M
A-21271 was used in immunohistochemistry to investigate brain regeneration mechanisms in adult zebrafish.
Tue Nov 01 00:00:00 UTC 2011
Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Guo F,Maeda Y,Ma J,Delgado M,Sohn J,Miers L,Ko EM,Bannerman P,Xu J,Wang Y,Zhou C,Takebayashi H,Pleasure D
A-21271 was used in immunohistochemistry to determine the origin of hypertrophic GFAP(+)/vimentin(+)/nestin(+) "reactive" astroglia.
Wed Aug 17 00:00:00 UTC 2011
Dopamine D2 receptor activity modulates Akt signaling and alters GABAergic neuron development and motor behavior in zebrafish larvae.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Souza BR,Romano-Silva MA,Tropepe V
A-21271 was used in immunohistochemistry to use a zebrafish model to examine the impact of altered dopamine signaling on brain development and larval motor behavior.
Wed Apr 06 00:00:00 UTC 2011
Authentically phosphorylated α-synuclein at Ser129 accelerates neurodegeneration in a rat model of familial Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Sato H,Arawaka S,Hara S,Fukushima S,Koga K,Koyama S,Kato T
A-21271 was used in western blot to elucidate the role of Ser129 phosphorylation in α-syn neurotoxicity.
Wed Nov 16 00:00:00 UTC 2011
Homeodomain interacting protein kinase 2 regulates postnatal development of enteric dopaminergic neurons and glia via BMP signaling.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Chalazonitis A,Tang AA,Shang Y,Pham TD,Hsieh I,Setlik W,Gershon MD,Huang EJ
A-21271 was used in immunohistochemistry to elucidate mechanisms that regulate the maturation of enteric neurons in postnatal life.
Wed Sep 28 00:00:00 UTC 2011
Paraneoplastic disorders of eye movements.
Annals of the New York Academy of Sciences
Wray SH,Dalmau J,Chen A,King S,Leigh RJ
A-21271 was used in immunohistochemistry to study upbeat nystagmus in a female patient with pancreatic cancer.
Thu Sep 01 00:00:00 UTC 2011
The RNA-binding protein HuR promotes glioma growth and treatment resistance.
Molecular cancer research : MCR
Filippova N,Yang X,Wang Y,Gillespie GY,Langford C,King PH,Wheeler C,Nabors LB
A-21271 was used in western blot to investigate the role of HuR in brain tumor growth.
Sun May 01 00:00:00 UTC 2011
Gastrointestinal neuromuscular pathology in alpers disease.
The American journal of surgical pathology
Kapur RP,Fligner C,Maghsoodi B,Jaffe R
A-21271 was used in immunohistochemistry - paraffin section to examine the gastrointestinal neuromuscular pathology in patients with Alpers disease.
Sun May 01 00:00:00 UTC 2011
GABAergic signalling in a neurogenic niche of the turtle spinal cord.
The Journal of physiology
Reali C,Fernández A,Radmilovich M,Trujillo-Cenóz O,Russo RE
A-21271 was used in immunohistochemistry to study the action of GABA around the central canal of the turtle spinal cord.
Thu Dec 01 00:00:00 UTC 2011
Nervous system disruption and concomitant behavioral abnormality in early hatched pufferfish larvae exposed to heavy oil.
Environmental science and pollution research international
Kawaguchi M,Sugahara Y,Watanabe T,Irie K,Ishida M,Kurokawa D,Kitamura S,Takata H,Handoh IC,Nakayama K,Murakami Y
A-21271 was used in immunohistochemistry to clarify the toxicological effects of heavy oil on fish eggs.
Mon Aug 01 00:00:00 UTC 2011
Calbindin immunoreactivity in the enteric nervous system of larval and adult zebrafish (Danio rerio).
Cell and tissue research
Olsson C
A-21271 was used in immunohistochemistry to study calbindin in the gut of adult and larval zebrafish.
Fri Apr 01 00:00:00 UTC 2011
Immunolocalization of aquaporin-4 in the brain, kidney, skeletal muscle, and gastro-intestinal tract of chicken.
Cell and tissue research
Yoshimura K,Sugiura K,Ohmori Y,Aste N,Saito N
A-21271 was used in immunohistochemistry - frozen section to report the distribution of chicken aquaporin-4.
Fri Apr 01 00:00:00 UTC 2011
Postnatal intestinal engraftment of prospectively selected enteric neural crest stem cells in a rat model of Hirschsprung disease.
Neurogastroenterology and motility
Tsai YH,Murakami N,Gariepy CE
A-21271 was used in immunohistochemistry - frozen section to investigate the therapeutic potential of enteric neural crest stem cells in Hirschsprung disease.
Fri Apr 01 00:00:00 UTC 2011
Neurovascular development in the embryonic zebrafish hindbrain.
Developmental biology
Ulrich F,Ma LH,Baker RG,Torres-Vázquez J
A-21271 was used in immunohistochemistry to investigate the assembly of the cerebral vasculature.
Thu Sep 01 00:00:00 UTC 2011
Subnuclear development of the zebrafish habenular nuclei requires ER translocon function.
Developmental biology
Doll CA,Burkart JT,Hope KD,Halpern ME,Gamse JT
A-21271 was used in immunohistochemistry to assess the contribution of sec61al1 in the formation of bilaterally symmetric habenular nuclei.
Thu Dec 01 00:00:00 UTC 2011
Aquaporin 1 water channel is expressed on submucosal but not myenteric neurons from the ovine duodenum.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
Arciszewski MB,Stefaniak M,Zacharko-Siembida A,Całka J
A-21271 was used in immunohistochemistry to determine the localization of aquaporin 1 in the sheep duodenum.
Tue Mar 01 00:00:00 UTC 2011
Lineage analysis of newly generated neurons in organotypic culture of rat hippocampus.
Neuroscience research
Yokose J,Ishizuka T,Yoshida T,Aoki J,Koyanagi Y,Yawo H
A-21271 was used in immunohistochemistry to determine the origin of new neurons in the hippocampus.
Tue Mar 01 00:00:00 UTC 2011
Calbindin-immunoreactive cells in the fish enteric nervous system.
Autonomic neuroscience : basic & clinical
Olsson C
A-21271 was used in immunohistochemistry to examine calbindin immunoreactivity in the enteric nervous system of the teleost shorthorn sculpin
Thu Jan 20 00:00:00 UTC 2011
Corticotropin releasing factor-distribution in rat intestine and role in neuroprotection.
Regulatory peptides
Sand E,Themner-Persson A,Ekblad E
A-21271 was used in immunocytochemistry to study the localization of corticotropin releasing factor in rat small and large intestines and study its role in nerve survival
Mon Jan 17 00:00:00 UTC 2011
Sequential generation of olfactory bulb glutamatergic neurons by Neurog2-expressing precursor cells.
Neural development
Winpenny E,Lebel-Potter M,Fernandez ME,Brill MS,Götz M,Guillemot F,Raineteau O
A-21271 was used in immunohistochemistry to study the different subtypes of glutamatergic OB interneurons.
Tue Apr 05 00:00:00 UTC 2011
Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells.
PloS one
Janardhan SV,Praveen K,Marks R,Gajewski TF
A-21271 was used in western blot to identify pathways that can functionally replace CD28-mediated costimulation in normal T cells.
Fri Feb 03 00:00:00 UTC 2012
Dynamic expression of cadherins regulates vocal development in a songbird.
PloS one
Matsunaga E,Suzuki K,Kato S,Kurotani T,Kobayashi K,Okanoya K
A-21271 was used in western blot to elucidate the molecular mechanisms that regulate avian vocal development.
Fri Feb 03 00:00:00 UTC 2012
Increased proportion of nitric oxide synthase immunoreactive neurons in rat ileal myenteric ganglia after severe acute pancreatitis.
BMC gastroenterology
Lin Z,Liu Y,Zheng Q,Hu Q
A-21271 was used in immunohistochemistry to examine the contribution of nitric oxide synthase-immunoreactive neurons to pancreatitis-induced ileus
Wed Nov 23 00:00:00 UTC 2011
MAZe: a tool for mosaic analysis of gene function in zebrafish.
Nature methods
Collins RT,Linker C,Lewis J
A-21271 was used in immunohistochemistry to create tools to help make inducible knockout zebrafish
Mon Mar 01 00:00:00 UTC 2010
Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats.
Gastroenterology
Soret R,Chevalier J,De Coppet P,Poupeau G,Derkinderen P,Segain JP,Neunlist M
A-21271 was used in Immunohistochemistry-immunofluorescence to investigate the effects of short-chain fatty acids on the enteric nervous system and colonic motility.
Sat May 01 00:00:00 UTC 2010
Differential actions of urocortins on neurons of the myenteric division of the enteric nervous system in guinea pig distal colon.
British journal of pharmacology
Liu S,Ren W,Qu MH,Bishop GA,Wang GD,Wang XY,Xia Y,Wood JD
A-21271 was used in immunohistochemistry to test if urocortins in the enteric nervous system regulate colonic motor behavior
Fri Jan 01 00:00:00 UTC 2010
Biogenesis of GPI-anchored proteins is essential for surface expression of sodium channels in zebrafish Rohon-Beard neurons to respond to mechanosensory stimulation.
Development (Cambridge, England)
Nakano Y,Fujita M,Ogino K,Saint-Amant L,Kinoshita T,Oda Y,Hirata H
A-21271 was used in immunohistochemistry to study the contribution of sodium channels to mechanosensory responses in zebrafish
Sat May 01 00:00:00 UTC 2010
Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos.
Development (Cambridge, England)
Kawaguchi J,Nichols J,Gierl MS,Faial T,Smith A
A-21271 was used in Immunocytochemistry to investigate the generation, maintenance, and expansion of neural crest progenitors.
Mon Mar 01 00:00:00 UTC 2010
Protogenin defines a transition stage during embryonic neurogenesis and prevents precocious neuronal differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Wong YH,Lu AC,Wang YC,Cheng HC,Chang C,Chen PH,Yu JY,Fann MJ
A-21271 was used in immunocytochemistry to determine the expression and function of protogenin in the developing nervous system
Wed Mar 24 00:00:00 UTC 2010
Embryonic retinal cells and support to mature retinal neurons.
Investigative ophthalmology & visual science
Stanke JJ,Fischer AJ
A-21271 was used in immunohistochemistry to test if transplanted embryonic retinal cells from various stages of development influence the survival of mature ganglion cells
Thu Apr 01 00:00:00 UTC 2010
Glial cells revealed by GFAP immunoreactivity in fish gut.
Cell and tissue research
Hagström C,Olsson C
A-21271 was used in immunohistochemistry - frozen section to determine the localization of glial fibrillary acidic protein immunoreactivity in adult and developing fish
Thu Jul 01 00:00:00 UTC 2010
Inhibitory neuromuscular transmission to ileal longitudinal muscle predominates in neonatal guinea pigs.
Neurogastroenterology and motility
Patel BA,Dai X,Burda JE,Zhao H,Swain GM,Galligan JJ,Bian X
A-21271 was used in immunohistochemistry to discuss neurotransmission to the longitudinal muscle in neonatal and adult guinea pig ileum
Sun Aug 01 00:00:00 UTC 2010
Glial fibrillary acidic protein-expressing neural progenitors give rise to immature neurons via early intermediate progenitors expressing both glial fibrillary acidic protein and neuronal markers in the adult hippocampus.
Neuroscience
Liu Y,Namba T,Liu J,Suzuki R,Shioda S,Seki T
A-21271 was used in immunohistochemistry - free floating to investigate how astrocyte-like progenitors differentiate into neuron-committed progenitors
Wed Mar 10 00:00:00 UTC 2010
Inhibition of caspase-3-mediated apoptosis improves spinal cord repair in a regeneration-competent vertebrate system.
Neuroscience
Sîrbulescu RF,Zupanc GK
A-21271 was used in immunohistochemistry to use teleost fish to test if inhibition of apoptosis after injury enhances spinal cord regeneration
Wed Dec 01 00:00:00 UTC 2010
Microvillous cells expressing IP3 receptor type 3 in the olfactory epithelium of mice.
The European journal of neuroscience
Hegg CC,Jia C,Chick WS,Restrepo D,Hansen A
A-21271 was used in immunohistochemistry - frozen section to characterize cells expressing IP3 receptor type 3 in the olfactory epithelium
Mon Nov 01 00:00:00 UTC 2010
Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons.
Developmental biology
Peltopuro P,Kala K,Partanen J
A-21271 was used in immunohistochemistry - paraffin section to study the distinct involvement of Asc11 in the development of different midbrain GABAergic neurone sub-populations
Thu Jul 01 00:00:00 UTC 2010
Expression of neuronal markers, synaptic proteins, and glutamine synthetase in the control and regenerating lizard visual system.
The Journal of comparative neurology
Romero-Alemán MM,Monzón-Mayor M,Santos E,Yanes C
A-21271 was used in immunohistochemistry and western blot to study the expression of neuronal markers, synaptic proteins, and glutamine synthetase during visual regeneration in lizards.
Fri Oct 01 00:00:00 UTC 2010
Area-specific migration and recruitment of new neurons in the adult songbird brain.
The Journal of comparative neurology
Vellema M,van der Linden A,Gahr M
A-21271 was used in immunohistochemistry to study neuronal migration and recruitment in the adult songbird brain
Sat May 01 00:00:00 UTC 2010
Identification of cerebellin2 in chick and its preferential expression by subsets of developing sensory neurons and their targets in the dorsal horn.
The Journal of comparative neurology
Yang M,Cagle MC,Honig MG
A-21271 was used in immunohistochemistry to identify cerebellin2 in chick and study its expression pattern
Thu Jul 15 00:00:00 UTC 2010
Neurochemical coding of enteric neurons in adult and embryonic zebrafish (Danio rerio).
The Journal of comparative neurology
Uyttebroek L,Shepherd IT,Harrisson F,Hubens G,Blust R,Timmermans JP,Van Nassauw L
A-21271 was used in immunohistochemistry to investigate the neurochemical coding of enteric neurons in zebrafish
Mon Nov 01 00:00:00 UTC 2010
Early acquisition of neural crest competence during hESCs neuralization.
PloS one
Curchoe CL,Maurer J,McKeown SJ,Cattarossi G,Cimadamore F,Nilbratt M,Snyder EY,Bronner-Fraser M,Terskikh AV
A-21271 was used in immunocytochemistry and immunohistochemistry to discuss neural crest stem cells
Tue Nov 09 00:00:00 UTC 2010
Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish.
Gastroenterology
de Jong-Curtain TA,Parslow AC,Trotter AJ,Hall NE,Verkade H,Tabone T,Christie EL,Crowhurst MO,Layton JE,Shepherd IT,Nixon SJ,Parton RG,Zon LI,Stainier DY,Lieschke GJ,Heath JK
A-21271 was used in immunohistochemistry to identify the gene impacted in the "flotte lotte" zebrafish mutant
Sun Mar 01 00:00:00 UTC 2009
Cellular glutathione peroxidase in human brain: cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies.
Acta neuropathologica
Power JH,Blumbergs PC
A-21271 was used in immunohistochemistry to determine the expression of glutathione peroxidase in control, Parkinson's disease, and dementia with Lewy bodies tissues
Thu Jan 01 00:00:00 UTC 2009
Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio).
Brain : a journal of neurology
Flinn L,Mortiboys H,Volkmann K,Köster RW,Ingham PW,Bandmann O
A-21271 was used in immunocytochemistry to develop and characterize a zebrafish model for Parkin deficiency
Mon Jun 01 00:00:00 UTC 2009
Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons.
Molecular therapy : the journal of the American Society of Gene Therapy
Ulusoy A,Sahin G,Björklund T,Aebischer P,Kirik D
A-21271 was used in Immunohistochemistry to demonstrate that long-term, efficient knockdown of tyrosine hydroxylase in the absence of any apparent nonspecific toxicity can be obtained using an rAAV-mediated shRNA delivery.
Tue Sep 01 00:00:00 UTC 2009
Mitogen-activated protein kinase-signaling stimulates Müller glia to proliferate in acutely damaged chicken retina.
Glia
Fischer AJ,Scott MA,Tuten W
A-21271 was used in immunohistochemistry - frozen section to determine the roles of the mitogen-activated protein kinase pathway in regulating the activity of Muller glia in the chicken retina
Thu Jan 15 00:00:00 UTC 2009
Morphogenesis and cytodifferentiation of the avian retinal pigmented epithelium require downregulation of Group B1 Sox genes.
Development (Cambridge, England)
Ishii Y,Weinberg K,Oda-Ishii I,Coughlin L,Mikawa T
A-21271 was used in immunohistochemistry to suggest that retinal pigment epithelium morphogenesis and cytodifferentiation requires SoxB1 downregulation and an absence of FGF-like signal
Sat Aug 01 00:00:00 UTC 2009
Gata2 is a tissue-specific post-mitotic selector gene for midbrain GABAergic neurons.
Development (Cambridge, England)
Kala K,Haugas M,Lilleväli K,Guimera J,Wurst W,Salminen M,Partanen J
A-21271 was used in immunohistochemistry - paraffin section to study the role of the Gata2 transcription factor in midbrain GABAergic neurons
Thu Jan 01 00:00:00 UTC 2009
Mast cells reduce survival of myenteric neurons in culture.
Neuropharmacology
Sand E,Themner-Persson A,Ekblad E
A-21271 was used in immunocytochemistry to examine the impact of mast cells on neuronal survival and plasticity of myenteric neurons
Sun Feb 01 00:00:00 UTC 2009
Brain-endocrine interactions: a microvascular route in the mediobasal hypothalamus.
Endocrinology
Ciofi P,Garret M,Lapirot O,Lafon P,Loyens A,Prévot V,Levine JE
A-21271 was used in immunohistochemistry to study the brain-endocrine interactions in the mediobasal hypothalamus.
Tue Dec 01 00:00:00 UTC 2009
Development of microglia in the chick embryo spinal cord: implications in the regulation of motoneuronal survival and death.
Journal of neuroscience research
Calderó J,Brunet N,Ciutat D,Hereu M,Esquerda JE
A-21271 was used in immunocytochemistry to study the development of microglia in the spinal cord and characterize their changes in response to naturally occurring and pathological death of motoneurons
Sat Aug 15 00:00:00 UTC 2009
Quantitative evaluation of myenteric ganglion cells in normal human left colon: implications for histopathological analysis.
Cell and tissue research
Ippolito C,Segnani C,De Giorgio R,Blandizzi C,Mattii L,Castagna M,Moscato S,Dolfi A,Bernardini N
A-21271 was used in immunohistochemistry - paraffin section to find a method to detect and count myenteric neurons and glial cells in paraffin sections of human colon
Fri May 01 00:00:00 UTC 2009
Fall in density, but not number of myenteric neurons and circular muscle nerve fibres in guinea-pig colon with ageing.
Neurogastroenterology and motility
Peck CJ,Samsuria SD,Harrington AM,King SK,Hutson JM,Southwell BR
A-21271 was used in immunohistochemistry to examine age-associated changes in the guinea-pig ileum
Thu Oct 01 00:00:00 UTC 2009
Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish.
Neurogastroenterology and motility
Field HA,Kelley KA,Martell L,Goldstein AM,Serluca FC
A-21271 was used in immunocytochemistry to develop a method for visualizing intestinal transit in larval zebrafish
Sun Mar 01 00:00:00 UTC 2009
Generation, long-term persistence, and neuronal differentiation of cells with nuclear aberrations in the adult zebrafish brain.
Neuroscience
Zupanc GK,Wellbrock UM,Sîrbulescu RF,Rajendran RS
A-21271 was used in immunohistochemistry to characterize nuclear aberrations present in zebrafish brains
Fri Apr 10 00:00:00 UTC 2009
Effects of estradiol on incorporation of new cells in the developing zebra finch song system: potential relationship to expression of ribosomal proteins L17 and L37.
Developmental neurobiology
Tang YP,Wade J
A-21271 was used in immunohistochemistry to compare estrogen and ribosomal protein expression in juvenile male and female zebra finches
Mon Jun 01 00:00:00 UTC 2009
Triple fluorescence labelling of neuronal, glial and vascular markers revealing pathological alterations in various animal models.
Journal of chemical neuroanatomy
Härtig W,Reichenbach A,Voigt C,Boltze J,Bulavina L,Schuhmann MU,Seeger J,Schusser GF,Freytag C,Grosche J
A-21271 was used in immunohistochemistry to develop a method for the carbocyanine triple fluorescence labelling of neuronal, vascular, and glial markers and use this technique to study a mouse model of Alzheimer's disease
Sun Mar 01 00:00:00 UTC 2009
Birth of ophthalmic trigeminal neurons initiates early in the placodal ectoderm.
The Journal of comparative neurology
McCabe KL,Sechrist JW,Bronner-Fraser M
A-21271 was used in immunohistochemistry to investigate the development of ophthalmic trigeminal neurons.
Sun May 10 00:00:00 UTC 2009
Excitotoxic motoneuron degeneration induced by glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.
The Journal of comparative neurology
Brunet N,Tarabal O,Esquerda JE,Calderó J
A-21271 was used in immunohistochemistry to investigate the excitotoxicity of glutamate receptor agonists and mitochondrial toxins in organotypic cultures of chick embryo spinal cord.
Thu Oct 01 00:00:00 UTC 2009
Identification of Wnt-responsive cells in the zebrafish hypothalamus.
Zebrafish
Wang X,Lee JE,Dorsky RI
A-21271 was used in immunohistochemistry to elucidate the exact roles of canonical Wnt signaling in neurogenesis
Sun Mar 01 00:00:00 UTC 2009
Use of phospholipase A2 for antigen retrieval in zebrafish whole-mount immunohistochemistry.
Zebrafish
Akhtar T,Li J,Olden T,Wallace KN
A-21271 was used in immunohistochemistry - paraffin section to discuss methods for antigen retrieval
Tue Sep 01 00:00:00 UTC 2009
Immunodetection of cocaine- and amphetamine-regulated transcript in the rumen, reticulum, omasum and abomasum of the sheep.
Anatomia, histologia, embryologia
Arciszewski MB,Barabasz S,Skobowiat C,Maksymowicz W,Majewski M
A-21271 was used in immunohistochemistry - frozen section to determine the distribution patterns of cocaine- and amphetamine-regulated transcript-immunoreactive nerve fibers and enteric neurons present in the rumen, reticulum, omasum, and abomasum of the
Sun Feb 01 00:00:00 UTC 2009
Myenteric neurons of the ileum that express somatostatin are a target of prion neuroinvasion in an alimentary model of sheep scrapie.
Acta neuropathologica
Schneider DA,Yan H,Fry LM,Alverson J,White SN,O'Rourke KI
A-21271 was used in immunohistochemistry - paraffin section to study enteric neuroinvasion by scrapie prions
Sun Jun 01 00:00:00 UTC 2008
Signals from the neural crest regulate beta-cell mass in the pancreas.
Development (Cambridge, England)
Nekrep N,Wang J,Miyatsuka T,German MS
A-21271 was used in Immunohistochemistry-immunofluorescence to identify the feedback mechanism by which the ectoderm derived neural crest influences the development of the endoderm derived pancreatic islet cells.
Sun Jun 01 00:00:00 UTC 2008
Gsk3beta/PKA and Gli1 regulate the maintenance of neural progenitors at the midbrain-hindbrain boundary in concert with E(Spl) factor activity.
Development (Cambridge, England)
Ninkovic J,Stigloher C,Lillesaar C,Bally-Cuif L
A-21271 was used in Immunohistochemistry to suggest a model in which the modulation of E(Spl) and Gsk3beta/PKA activities by Gli1 underlies the dynamic properties of intervening zone maintenance and recruitment.
Mon Sep 01 00:00:00 UTC 2008
Testosterone-induced matrix metalloproteinase activation is a checkpoint for neuronal addition to the adult songbird brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Kim DH,Lilliehook C,Roides B,Chen Z,Chang M,Mobashery S,Goldman SA
A-21271 was used in Immunohistochemistry to investigate the role of the gelatinases in neuronal addition to the HVC of adult female canaries.
Wed Jan 02 00:00:00 UTC 2008
Zebrafish dorsal root ganglia neural precursor cells adopt a glial fate in the absence of neurogenin1.
The Journal of neuroscience : the official journal of the Society for Neuroscience
McGraw HF,Nechiporuk A,Raible DW
A-21271 was used in immunohistochemistry to demonstrate that the neural crest population that gives rise to dorsal root ganglion neurons becomes fate restricted to a neuronal/glial precursor before the onset of neurog1 function using transgenic zebrafish
Wed Nov 19 00:00:00 UTC 2008
Activity-dependent expression of ELAV/Hu RBPs and neuronal mRNAs in seizure and cocaine brain.
Journal of neurochemistry
Tiruchinapalli DM,Caron MG,Keene JD
A-21271 was used in immunohistochemistry - frozen section and western blot to determine the localization of HuR and HuD RNA-binding proteins after seizure or cocaine treatment.
Mon Dec 01 00:00:00 UTC 2008
Smooth muscle NOS, colocalized with caveolin-1, modulates contraction in mouse small intestine.
Journal of cellular and molecular medicine
El-Yazbi AF,Cho WJ,Cena J,Schulz R,Daniel EE
A-21271 was used in immunohistochemistry - frozen section to investigate the functions of nNOS in mouse small intestinal smooth muscle
Fri Aug 01 00:00:00 UTC 2008
Sex differences in serotonergic but not gamma-aminobutyric acidergic (GABA) projections to the rat ventromedial nucleus of the hypothalamus.
Endocrinology
Patisaul HB,Fortino AE,Polston EK
A-21271 was used in immunohistochemistry to study sex differences that contribute to development of lordosis.
Tue Jan 01 00:00:00 UTC 2008
Leptin-dependent STAT3 phosphorylation in postnatal mouse hypothalamus.
Brain research
Frontini A,Bertolotti P,Tonello C,Valerio A,Nisoli E,Cinti S,Giordano A
A-21271 was used in immunohistochemistry to investigate the timing of maturation of the leptin signal transduction system
Wed Jun 18 00:00:00 UTC 2008
A novel role for zebrafish zic2a during forebrain development.
Developmental biology
Sanek NA,Grinblat Y
A-21271 was used in immunohistochemistry to identify Zic2a as a novel regulator of prethalamic development in zebrafish
Thu May 01 00:00:00 UTC 2008
Endoderm-derived Sonic hedgehog and mesoderm Hand2 expression are required for enteric nervous system development in zebrafish.
Developmental biology
Reichenbach B,Delalande JM,Kolmogorova E,Prier A,Nguyen T,Smith CM,Holzschuh J,Shepherd IT
A-21271 was used in Immunohistochemistry to show that endoderm and HH signaling, but not hand2, regulate gdnf expression in the intestine, highlighting a central role of endoderm and SHH in patterning the intestine and the ENS.
Sun Jun 01 00:00:00 UTC 2008
Intrinsic neuronal control of the pyloric sphincter of the lamb.
Journal of chemical neuroanatomy
Mazzuoli G,Lucherini MC,Russo D,Clavenzani P,Chiocchetti R
A-21271 was used in immunohistochemistry to examine the enteric nervous system innervating the pyloric sphincter of the lamb abomasum
Wed Oct 01 00:00:00 UTC 2008
Distribution of calretinin during development of the olfactory system in the brown trout, Salmo trutta fario: Comparison with other immunohistochemical markers.
Journal of chemical neuroanatomy
Castro A,Becerra M,Anadón R,Manso MJ
A-21271 was used in immunohistochemistry - paraffin section to study the appearance and distribution of calretinin in the olfactory system of developing and adult brown trout
Tue Jul 01 00:00:00 UTC 2008
Fate mapping Nkx2.1-lineage cells in the mouse telencephalon.
The Journal of comparative neurology
Xu Q,Tam M,Anderson SA
A-21271 was used in immunohistochemistry to study the contribution of Nkx2.1 lineages to neurons in the mature telencephalon
Tue Jan 01 00:00:00 UTC 2008
Developmental and spatial expression pattern of alpha-taxilin in the rat central nervous system.
The Journal of comparative neurology
Sakakibara S,Nakadate K,Tanaka-Nakadate S,Yoshida K,Nogami S,Shirataki H,Ueda S
A-21271 was used in immunohistochemistry to localize alpha-taxilin in the rat central nervous system.
Sat Nov 01 00:00:00 UTC 2008
Quantitative assessment of glial cells in the human and guinea pig enteric nervous system with an anti-Sox8/9/10 antibody.
The Journal of comparative neurology
Hoff S,Zeller F,von Weyhern CW,Wegner M,Schemann M,Michel K,Rühl A
A-21271 was used in immunohistochemistry to quantitate glial cells in the human and guinea pig enteric nervous system.
Fri Aug 01 00:00:00 UTC 2008
Differential expression of canonical (classical) transient receptor potential channels in guinea pig enteric nervous system.
The Journal of comparative neurology
Liu S,Qu MH,Ren W,Hu HZ,Gao N,Wang GD,Wang XY,Fei G,Zuo F,Xia Y,Wood JD
A-21271 was used in immunohistochemistry to study canonical transient receptor potential channels in guinea pig enteric nervous system.
Sat Dec 20 00:00:00 UTC 2008
Fgf signaling in the zebrafish adult brain: association of Fgf activity with ventricular zones but not cell proliferation.
The Journal of comparative neurology
Topp S,Stigloher C,Komisarczuk AZ,Adolf B,Becker TS,Bally-Cuif L
A-21271 was used in immunohistochemistry to investigate the role of FGF in stem cell maintenance and neurogenesis in zebrafish
Wed Oct 01 00:00:00 UTC 2008
Development of enteric and vagal innervation of the zebrafish (Danio rerio) gut.
The Journal of comparative neurology
Olsson C,Holmberg A,Holmgren S
A-21271 was used in immunohistochemistry to study the neuronal development in the zebrafish gut.
Tue Jun 10 00:00:00 UTC 2008
Notch-regulated oligodendrocyte specification from radial glia in the spinal cord of zebrafish embryos.
Developmental dynamics : an official publication of the American Association of Anatomists
Kim H,Shin J,Kim S,Poling J,Park HC,Appel B
A-21271 was used in Immunocytochemistry to investigate formation of radial glia in the spinal cord of zebrafish and the role of Notch signalling in their maintenance and specification.
Fri Aug 01 00:00:00 UTC 2008
Nest of origin predicts adult neuron addition rates in the vocal control system of the zebra finch.
Brain, behavior and evolution
Hurley P,Pytte C,Kirn JR
A-21271 was used in Immunohistochemistry to explore the extent to which nest of origin predicts rates of HVC neuron addition in adult male zebra finches.
Thu Jul 17 00:00:00 UTC 2008
Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord.
PLoS genetics
Montpetit A,Côté S,Brustein E,Drouin CA,Lapointe L,Boudreau M,Meloche C,Drouin R,Hudson TJ,Drapeau P,Cossette P
A-21271 was used in immunohistochemistry to describe the first mutation in the human AP1S1 gene
Mon Dec 01 00:00:00 UTC 2008
Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits.
PloS one
Ponti G,Peretto P,Bonfanti L
A-21271 was used in Immunohistochemistry to reveal that adult cerebellar neurogenesis can exist in some mammals, and therefore provide a suitable model for studying adult nervous tissue permissiveness.
Wed Jun 04 00:00:00 UTC 2008
Vasoactive intestinal peptide rescues cultured rat myenteric neurons from lipopolysaccharide induced cell death.
Regulatory peptides
Arciszewski MB,Sand E,Ekblad E
A-21271 was used in immunocytochemistry to assess the effects of lipopolysaccharide on enteric neurons
Thu Feb 07 00:00:00 UTC 2008
Regional variation in the neurochemical coding of the myenteric plexus of the human colon and changes in patients with slow transit constipation.
Neurogastroenterology and motility
Wattchow D,Brookes S,Murphy E,Carbone S,de Fontgalland D,Costa M
A-21271 was used in Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot to compare density of innervation between regions and between normal patients and those undergoing resection for severe constipation.
Mon Dec 01 00:00:00 UTC 2008
Demonstration of functional neuronal beta3-adrenoceptors within the enteric nervous system.
Gastroenterology
Cellek S,Thangiah R,Bassil AK,Campbell CA,Gray KM,Stretton JL,Lalude O,Vivekanandan S,Wheeldon A,Winchester WJ,Sanger GJ,Schemann M,Lee K
A-21271 was used in Immunofluorescence in immunohistochemistry on frozen tissues to investigate the expression of beta(3)-AR in human enteric nervous system and its role in motility and visceral algesia.
Sun Jul 01 00:00:00 UTC 2007
Mitotic spindle orientation distinguishes stem cell and terminal modes of neuron production in the early spinal cord.
Development (Cambridge, England)
Wilcock AC,Swedlow JR,Storey KG
A-21271 was used in Immunocytochemistry to support a model in which cleavage plane orientation/mitotic spindle position does not assign neuron-generating ability.
Tue May 01 00:00:00 UTC 2007
Postnatal generation of neurons in the ventrobasal nucleus of the rat thalamus.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Mooney SM,Miller MW
A-21271 was used in Immunohistochemistry to examine whether the development of the trigeminal system can proceed via a nonhierarchical mechanism in the rat thalamus.
Wed May 09 00:00:00 UTC 2007
Cross talk between notch and growth factor/cytokine signaling pathways in neural stem cells.
Molecular and cellular biology
Nagao M,Sugimori M,Nakafuku M
A-21271 was used in immunocytochemistry to study Notch signaling in neural stem cells
Fri Jun 01 00:00:00 UTC 2007
Quantification of subclasses of human colonic myenteric neurons by immunoreactivity to Hu, choline acetyltransferase and nitric oxide synthase.
Neurogastroenterology and motility
Murphy EM,Defontgalland D,Costa M,Brookes SJ,Wattchow DA
A-21271 was used in immunohistochemistry to characterize myenteric neurons
Thu Feb 01 00:00:00 UTC 2007
Characterization of CaMKII-expressing neurons within a striatal region implicated in avian vocal learning.
Brain research
Hein AM,Sridharan A,Nordeen KW,Nordeen EJ
A-21271 was used in immunohistochemistry to study implication in avian vocal learning by characterizing CaMKII-expressing neurons within a striatal region
Mon Jun 25 00:00:00 UTC 2007
TTX-sensitive and TTX-insensitive control of spontaneous gut motility in the developing zebrafish (Danio rerio) larvae.
The Journal of experimental biology
Holmberg A,Olsson C,Hennig GW
A-21271 was used in immunohistochemistry to analyze the roles of intrinsic and extrinsic innervation for initiating and propagating the spontaneous contractions in the developing zebrafish gut
Thu Mar 01 00:00:00 UTC 2007
Purinergic signaling regulates neural progenitor cell expansion and neurogenesis.
Developmental biology
Lin JH,Takano T,Arcuino G,Wang X,Hu F,Darzynkiewicz Z,Nunes M,Goldman SA,Nedergaard M
A-21271 was used in Immunocytochemistry to suggest progenitor cell-derived neurogenesis is thus associated with regions of both active purinergic signaling and modulation thereof.
Thu Feb 01 00:00:00 UTC 2007
Cytological organization of the central gelatinosa in the turtle spinal cord.
The Journal of comparative neurology
Trujillo-Cenóz O,Fernández A,Radmilovich M,Reali C,Russo RE
A-21271 was used in immunohistochemistry to investigate the central gelatinosa in the turtle spinal cord
Thu May 10 00:00:00 UTC 2007
Dynamic expression of the basic helix-loop-helix transcription factor neuroD in the rod and cone photoreceptor lineages in the retina of the embryonic and larval zebrafish.
The Journal of comparative neurology
Ochocinska MJ,Hitchcock PF
A-21271 was used in immunocytochemistry to study the role of the basic helix-loop-helix transcription factor neuroD during the development of rod and cone photoreceptors.
Thu Mar 01 00:00:00 UTC 2007
FnTm2, a novel brain-specific transcript, is dynamically expressed in the song learning circuit of the zebra finch.
The Journal of comparative neurology
Agate RJ,Hertel M,Nottebohm F
A-21271 was used in immunohistochemistry to study the role of FnTm2 (Phantom 2) in learned song.
Mon Sep 10 00:00:00 UTC 2007
Identification of aromatase-positive radial glial cells as progenitor cells in the ventricular layer of the forebrain in zebrafish.
The Journal of comparative neurology
Pellegrini E,Mouriec K,Anglade I,Menuet A,Le Page Y,Gueguen MM,Marmignon MH,Brion F,Pakdel F,Kah O
A-21271 was used in immunohistochemistry to identify progenitor cells in the ventricular layer of the zebrafish forebrain.
Thu Mar 01 00:00:00 UTC 2007
Na(v)1.7 and Na(v)1.3 are the only tetrodotoxin-sensitive sodium channels expressed by the adult guinea pig enteric nervous system.
The Journal of comparative neurology
Sage D,Salin P,Alcaraz G,Castets F,Giraud P,Crest M,Mazet B,Clerc N
A-21271 was used in immunohistochemistry to determine the localization of the Na(v)1.7 alpha subunit in the guinea pig myenteric ganglia.
Mon Oct 01 00:00:00 UTC 2007
Morphology and neurochemistry of descending and ascending myenteric plexus neurons of sheep ileum.
Anatomical record (Hoboken, N.J. : 2007)
Mazzuoli G,Mazzoni M,Albanese V,Clavenzani P,Lalatta-Costerbosa G,Lucchi ML,Furness JB,Chiocchetti R
A-21271 was used in immunohistochemistry to characterize myenteric plexus neurons of the sheep ileum
Sat Dec 01 00:00:00 UTC 2007
Regeneration of neural crest derivatives in the Xenopus tadpole tail.
BMC developmental biology
Lin G,Chen Y,Slack JM
A-21271 was used in immunohistochemistry - paraffin section to study the regeneration of the neural crest derivatives in the Xenopus tadpole tail
Thu May 24 00:00:00 UTC 2007
Survival and neurotransmitter plasticity in cultured rat colonic myenteric neurons.
Regulatory peptides
Kristensson E,Themner-Persson A,Ekblad E
A-21271 was used in immunohistochemistry - frozen section to count the rat colonic myenteric neuronal cells that express calcitonin gene-related peptide, galanin, neuropeptide Y, somatostatin, vasoactive intestinal peptide, and nitric oxide synthase
Thu May 03 00:00:00 UTC 2007
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow.
Gastroenterology
Guan X,Karpen HE,Stephens J,Bukowski JT,Niu S,Zhang G,Stoll B,Finegold MJ,Holst JJ,Hadsell D,Nichols BL,Burrin DG
A-21271 was used in Immunohistochemistry to establish cellular localisation of glucagon-like peptide-2 (GLP-2) receptor and functional connection to vascular action of GLP-2 in the gut.
Sun Jan 01 00:00:00 UTC 2006
Efficient generation of retinal progenitor cells from human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America
Lamba DA,Karl MO,Ware CB,Reh TA
A-21271 was used in immunocytochemistry to determine how human embryonic stem cells are efficiently generated from retinal progenitor cells
Tue Aug 22 00:00:00 UTC 2006
Oligodendrocytes are a major target of the toxicity of spongiogenic murine retroviruses.
The American journal of pathology
Clase AC,Dimcheff DE,Favara C,Dorward D,McAtee FJ,Parrie LE,Ron D,Portis JL
A-21271 was used in immunohistochemistry - paraffin section to identify the cells infected by FrCasE and Moloney MLV-ts1 viruses
Fri Sep 01 00:00:00 UTC 2006
Platelet-activating factor in the enteric nervous system of the guinea pig small intestine.
American journal of physiology. Gastrointestinal and liver physiology
Wang GD,Wang XY,Hu HZ,Fang XC,Liu S,Gao N,Xia Y
A-21271 was used in Immunohistochemistry-immunofluorescence to study the action of platelet-activating factor (PAF) and the expression of PAF receptor in the enteric nervous system.
Wed Nov 01 00:00:00 UTC 2006
Extrinsic and intrinsic sources of calcitonin gene-related peptide immunoreactivity in the lamb ileum: a morphometric and neurochemical investigation.
Cell and tissue research
Chiocchetti R,Grandis A,Bombardi C,Lucchi ML,Dal Lago DT,Bortolami R,Furness JB
A-21271 was used in immunohistochemistry - frozen section to examine the extrinsic origins of calcitonin gene-related peptide immunoreactive nerve fibers in the sheep ileum
Wed Feb 01 00:00:00 UTC 2006
Formation of the avian nucleus magnocellularis from the auditory anlage.
The Journal of comparative neurology
Hendricks SJ,Rubel EW,Nishi R
A-21271 was used in immunohistochemistry to study the development of avian auditory system
Sun Oct 01 00:00:00 UTC 2006
Mitral cells in the olfactory bulb of adult zebrafish (Danio rerio): morphology and distribution.
The Journal of comparative neurology
Fuller CL,Yettaw HK,Byrd CA
A-21271 was used in immunohistochemistry to identify mitral cells in the olfactory bulb of adult zebrafish
Fri Nov 10 00:00:00 UTC 2006
Comparison of extrinsic efferent innervation of guinea pig distal colon and rectum.
The Journal of comparative neurology
Olsson C,Chen BN,Jones S,Chataway TK,Costa M,Brookes SJ
A-21271 was used in western blot to compare the extrinsic efferent innervation of the distal colon and rectum of guinea pigs.
Tue Jun 20 00:00:00 UTC 2006
Distribution and chemical coding of corticotropin-releasing factor-immunoreactive neurons in the guinea pig enteric nervous system.
The Journal of comparative neurology
Liu S,Gao N,Hu HZ,Wang X,Wang GD,Fang X,Gao X,Xia Y,Wood JD
A-21271 was used in immunohistochemistry to localize corticotropin-releasing factor-immunoreactive neurons in the guinea pig enteric nervous system.
Sun Jan 01 00:00:00 UTC 2006
Morphology of VIP/nNOS-immunoreactive myenteric neurons in the human gut.
Histochemistry and cell biology
Brehmer A,Schrödl F,Neuhuber W
A-21271 was used in immunohistochemistry to characterized human myenteric neurons co-immunoreactive for neuronal nitric oxide synthase and vasoactive intestinal peptide
Mon May 01 00:00:00 UTC 2006
Investigation of general and cytoskeletal markers to estimate numbers and proportions of neurons in the human intestine.
Histology and histopathology
Ganns D,Schrödl F,Neuhuber W,Brehmer A
A-21271 was used in immunohistochemistry to compare panneuronal markers in the enteric nervous system
Sun Jan 01 00:00:00 UTC 2006
The use of embryonic stem cells to study hedgehog signaling.
Methods in molecular biology (Clifton, N.J.)
Becker S,Grabel L
A-21271 was used in immunocytochemistry to study the role of Hedgehog signaling in the differentiation of the neurectoderm and vascular cell types
Fri Aug 25 00:00:00 UTC 2006
Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair.
Development (Cambridge, England)
Ninkovic J,Tallafuss A,Leucht C,Topczewski J,Tannhäuser B,Solnica-Krezel L,Bally-Cuif L
A-21271 was used in immunohistochemistry to elucidate the molecular bases for lateral intervening zone formation
Sat Jan 01 00:00:00 UTC 2005
Nogo-A interacts with the Nogo-66 receptor through multiple sites to create an isoform-selective subnanomolar agonist.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Hu F,Liu BP,Budel S,Liao J,Chin J,Fournier A,Strittmatter SM
A-21271 was used in immunocytochemistry to define a novel Nogo-A-specific domain in Amino-Nogo that binds the Nogo-66 receptor
Wed Jun 01 00:00:00 UTC 2005
In vivo neurogenesis in the dorsal vagal complex of the adult rat brainstem.
Neuroscience
Bauer S,Hay M,Amilhon B,Jean A,Moyse E
A-21271 was used in immunohistochemistry - frozen section to determine the occurrence of neurogenesis in the dorsal vagal complex of adult rats
Tue Mar 22 00:00:00 UTC 2005
Lipopolysaccharide induces cell death in cultured porcine myenteric neurons.
Digestive diseases and sciences
Arciszewski M,Pierzynowski S,Ekblad E
A-21271 was used in immunohistochemistry - frozen section to study the effects of LPS on the survival and neurotransmitter expression of cultured porcine myenteric neurons
Thu Sep 01 00:00:00 UTC 2005
Sonic hedgehog and retinoic acid are not sufficient to induce motoneuron generation in the avian caudal neural tube.
Developmental biology
Afonso ND,Catala M
A-21271 was used in immunohistochemistry to study the development of the caudal neural tube
Tue Mar 15 00:00:00 UTC 2005
Functional expression of the peptide transporter PEPT2 in the mammalian enteric nervous system.
The Journal of comparative neurology
Rühl A,Hoppe S,Frey I,Daniel H,Schemann M
A-21271 was used in immunohistochemistry to study PEPT2 in the gastrointestinal tract.
Mon Sep 12 00:00:00 UTC 2005
Distribution and fate of cocaine- and amphetamine-regulated transcript peptide (CARTp)-expressing cells in rat urinary bladder: a developmental study.
The Journal of comparative neurology
Zvarova K,Vizzard MA
A-21271 was used in immunohistochemistry to assess the distribution and fate of cocaine- and amphetamine-regulated transcript peptide-immunoreactive structures in the neonatal and adult rat urinary bladder.
Mon Sep 05 00:00:00 UTC 2005
Sox10 overexpression induces neural crest-like cells from all dorsoventral levels of the neural tube but inhibits differentiation.
Developmental dynamics : an official publication of the American Association of Anatomists
McKeown SJ,Lee VM,Bronner-Fraser M,Newgreen DF,Farlie PG
A-21271 was used in Immunohistochemistry-immunofluorescence to examine the roles of SoxE genes in late neural crest migration and differentiation.
Wed Jun 01 00:00:00 UTC 2005
Morphology of enkephalin-immunoreactive myenteric neurons in the human gut.
Histochemistry and cell biology
Brehmer A,Lindig TM,Schrödl F,Neuhuber W,Ditterich D,Rexer M,Rupprecht H
A-21271 was used in immunohistochemistry to characterize leu-enkephalin positive neurons
Tue Feb 01 00:00:00 UTC 2005
Effects of total parenteral nutrition on rat enteric nervous system, intestinal morphology, and motility.
The Journal of surgical research
Ekelund M,Ekelund M,Qader SS,Hallén M,Ekblad E
A-21271 was used in immunohistochemistry - frozen section to examine the enteric nervous system and intestinal mobility of rats that received total parenteral nutrition
Fri Apr 01 00:00:00 UTC 2005
Neural crest migration methods in the chicken embryo.
Methods in molecular biology (Clifton, N.J.)
Elena de Bellard M,Bronner-Fraser M
A-21271 was used in immunohistochemistry to discuss methods to study neural cell migration
Thu Apr 21 00:00:00 UTC 2005
Effects of vasoactive intestinal peptide and galanin on survival of cultured porcine myenteric neurons.
Regulatory peptides
Arciszewski MB,Ekblad E
A-21271 was used in immunohistochemistry - frozen section to examine the roles of galanin and vasoactive intestinal peptide on small intestinal porcine myenteric neuron survival
Tue Feb 15 00:00:00 UTC 2005
NG2-expressing cells in the subventricular zone are type C-like cells and contribute to interneuron generation in the postnatal hippocampus.
The Journal of cell biology
Aguirre AA,Chittajallu R,Belachew S,Gallo V
A-21271 was used in immunohistochemistry - frozen section to assess the contribution to interneuron generation in the postnatal hippocampus by NG2-expression cells in the subventricular zone that are type C-like cells
Mon May 24 00:00:00 UTC 2004
Asymmetric production of surface-dividing and non-surface-dividing cortical progenitor cells.
Development (Cambridge, England)
Miyata T,Kawaguchi A,Saito K,Kawano M,Muto T,Ogawa M
A-21271 was used in Immunohistochemistry to study the cytogenetic and histogenetic events that trigger the emergence of the cortical plate.
Thu Jul 01 00:00:00 UTC 2004
An element in the alpha1-tubulin promoter is necessary for retinal expression during optic nerve regeneration but not after eye injury in the adult zebrafish.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Senut MC,Gulati-Leekha A,Goldman D
A-21271 was used in immunohistochemistry - frozen section to study the requirement for retinal expression during optic nerve regeneration by an element in the alpha1-tubulin promoter and not after eye injury in the adult zebrafish
Wed Sep 01 00:00:00 UTC 2004
Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture.
Stem cells (Dayton, Ohio)
Schulz TC,Noggle SA,Palmarini GM,Weiler DA,Lyons IG,Pensa KA,Meedeniya AC,Davidson BP,Lambert NA,Condie BG
A-21271 was used in immunocytochemistry to assess the ability of human embryonic stem cells to differentiate into dopamine-producing neurons in a simple serum-free suspension culture system
Thu May 12 00:00:00 UTC 2005
Specification of the retinal fate of mouse embryonic stem cells by ectopic expression of Rx/rax, a homeobox gene.
Molecular and cellular biology
Tabata Y,Ouchi Y,Kamiya H,Manabe T,Arai K,Watanabe S
A-21271 was used in immunocytochemistry to analyze ectopic expression of Rx/rax, a homeobox gene, that specifies the retinal fate of mouse embryonic stem cells
Sat May 01 00:00:00 UTC 2004
Action of bradykinin in the submucosal plexus of guinea pig small intestine.
The Journal of pharmacology and experimental therapeutics
Hu HZ,Gao N,Liu S,Ren J,Wang X,Xia Y,Wood JD
A-21271 was used in immunohistochemistry to use microelectrodes to study actions of bradykinin on electrical behavior of morphologically identified neurons and determine the localization of BK receptors in the submucosal plexus of guinea pig small intestine.
Thu Apr 01 00:00:00 UTC 2004
Characterisation of neurons expressing calbindin immunoreactivity in the ileum of the unweaned and mature sheep.
Cell and tissue research
Chiocchetti R,Grandis A,Bombardi C,Clavenzani P,Costerbosa GL,Lucchi ML,Furness JB
A-21271 was used in immunohistochemistry to test if CALB-IR expressed in sheep Dogiel type II cells
Mon Nov 01 00:00:00 UTC 2004
Molecular and functional analysis of hyperpolarisation-activated nucleotide-gated (HCN) channels in the enteric nervous system.
Neuroscience
Xiao J,Nguyen TV,Ngui K,Strijbos PJ,Selmer IS,Neylon CB,Furness JB
A-21271 was used in immunohistochemistry to determine the expression and localization of hyperpolarisation-activated nucleotide-gated isoforms in the enteric nervous systems of mice, rats and guinea-pigs
Mon Mar 07 00:00:00 UTC 2005
Quantification of neurons in the myenteric plexus: an evaluation of putative pan-neuronal markers.
Journal of neuroscience methods
Phillips RJ,Hargrave SL,Rhodes BS,Zopf DA,Powley TL
A-21271 was used in immunocytochemistry and immunohistochemistry to assess the efficacy of four putative pan-neuronal markers for the enteric nervous system
Sun Feb 15 00:00:00 UTC 2004
Increased expression of nitric oxide synthase in cultured neurons from adult rat colonic submucous ganglia.
Autonomic neuroscience : basic & clinical
Lin Z,Sandgren K,Ekblad E
A-21271 was used in immunohistochemistry - paraffin section to determine the expression of VIP and NOS in cultured submucous neurons from adult rat large intestine
Fri Jul 30 00:00:00 UTC 2004
Actions of bradykinin on electrical and synaptic behavior of neurones in the myenteric plexus of guinea-pig small intestine.
British journal of pharmacology
Hu HZ,Liu S,Gao N,Xia Y,Mostafa R,Ren J,Zafirov DH,Wood JD
A-21271 was used in immunohistochemistry to investigate the actions of bradykinin in neurons of the myenteric plexus of guinea-pig small intestine in vitro.
Tue Apr 01 00:00:00 UTC 2003
Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding.
The Journal of cell biology
McWhorter ML,Monani UR,Burghes AH,Beattie CE
A-21271 was used in western blot to demonstrate that Smn contributes to motor axon development.
Mon Sep 01 00:00:00 UTC 2003
Noradrenergic neurons in the zebrafish hindbrain are induced by retinoic acid and require tfap2a for expression of the neurotransmitter phenotype.
Development (Cambridge, England)
Holzschuh J,Barrallo-Gimeno A,Ettl AK,Durr K,Knapik EW,Driever W
A-21271 was used in immunohistochemistry to characterize tfap2a mutant zebrafish
Mon Dec 01 00:00:00 UTC 2003
Vasoactive intestinal peptide and nitric oxide promote survival of adult rat myenteric neurons in culture.
Journal of neuroscience research
Sandgren K,Lin Z,Fex Svenningsen A,Ekblad E
A-21271 was used in immunocytochemistry to test if vasoactive intestinal peptide and nitric oxide affect the survival of cultured, dissociated myenteric neurons
Sun Jun 01 00:00:00 UTC 2003
Evidence that two forms of choline acetyltransferase are differentially expressed in subclasses of enteric neurons.
Cell and tissue research
Chiocchetti R,Poole DP,Kimura H,Aimi Y,Robbins HL,Castelucci P,Furness JB
A-21271 was used in immunohistochemistry to compare peripheral ChAT distribution with that of the common form of ChAT
Wed Jan 01 00:00:00 UTC 2003
HuC/D confocal imaging points to olfactory migratory cells as the first cell population that expresses a post-mitotic neuronal phenotype in the chick embryo.
Neuroscience
Fornaro M,Geuna S,Fasolo A,Giacobini-Robecchi MG
A-21271 was used in immunohistochemistry - paraffin section to identify the first population of post-mitotic neurons in the developing nervous system of the chick embryo
Fri Mar 19 00:00:00 UTC 2004
Increased expression of vasoactive intestinal polypeptide in cultured myenteric neurons from adult rat small intestine.
Autonomic neuroscience : basic & clinical
Lin Z,Sandgren K,Ekblad E
A-21271 was used in immunocytochemistry to investigate vasoactive intestinal polypeptide and nitric oxide synthase in cultured myenteric ganglia and dissociated neurons.
Fri Aug 29 00:00:00 UTC 2003
Immunocytochemistry as a tool for zebrafish developmental neurobiology.
Methods in cell science : an official journal of the Society for In Vitro Biology
Novak AE,Ribera AB
A-21271 was used in immunohistochemistry to describe methods to observe antibody localization in zebrafish whole mount preparations
Tue Sep 21 00:00:00 UTC 2004
The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas.
Regulatory peptides
Wierup N,Svensson H,Mulder H,Sundler F
A-21271 was used in immunohistochemistry to determine if ghrelin is expressed in human pancreas.
Mon Jul 15 00:00:00 UTC 2002
Müller glia are a potential source of neural regeneration in the postnatal chicken retina.
Nature neuroscience
Fischer AJ,Reh TA
A-21271 was used in immunohistochemistry to show that the retina of postnatal chickens can generate new neurons
Thu Mar 01 00:00:00 UTC 2001
Retinal ganglion cell genesis requires lakritz, a Zebrafish atonal Homolog.
Neuron
Kay JN,Finger-Baier KC,Roeser T,Staub W,Baier H
A-21271 was used in immunohistochemistry to investigate the role of zebrafish lakritz (lak) locus in the developing retina.
Fri Jun 01 00:00:00 UTC 2001
Asymmetric inheritance of radial glial fibers by cortical neurons.
Neuron
Miyata T,Kawaguchi A,Okano H,Ogawa M
A-21271 was used in immunohistochemistry - frozen section to analyze the inheritance pattern of asymmetry by radial glial fibers by cortical neurons
Thu Sep 13 00:00:00 UTC 2001
Evidence of very early neuronal migration from the olfactory placode of the chick embryo.
Neuroscience
Fornaro M,Geuna S,Fasolo A,Giacobini-Robecchi MG
A-21271 was used in immunohistochemistry - paraffin section to study migration of cells from the olfactory neuroepithelium in chickens
Mon Dec 17 00:00:00 UTC 2001
P2X(7) receptors in the enteric nervous system of guinea-pig small intestine.
The Journal of comparative neurology
Hu HZ,Gao N,Lin Z,Gao C,Liu S,Ren J,Xia Y,Wood JD
A-21271 was used in immunohistochemistry to investigate the role of P2X(7) receptors in the enteric nervous system.
Mon Nov 19 00:00:00 UTC 2001
Confocal imaging of HuC/D RNA-binding proteins in adult rat primary sensory neurons.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
Fornaro M,Geuna S
A-21271 was used in immunohistochemistry - paraffin section to determine the cellular distribution of HuC/D RNA-binding proteins in adult rat primary sensory neurons
Sat Sep 01 00:00:00 UTC 2001
Hu antigen specificities of ANNA-I autoantibodies in paraneoplastic neurological disease.
Journal of autoimmunity
King PH,Redden D,Palmgren JS,Nabors LB,Lennon VA
A-21271 was used in ELISA and western blot to correlate the immunoreactivity of all four Hu antigens in sera from 75 patients with ANNA-1 autoantibodies with clinical parameters
Wed Dec 01 00:00:00 UTC 1999
Hu protein as an early marker of neuronal phenotypic differentiation by subependymal zone cells of the adult songbird forebrain.
Journal of neurobiology
Barami K,Iversen K,Furneaux H,Goldman SA
A-21271 was used in immunohistochemistry and western blot to follow the commitment of newborn cells to neuronal lineage in the avian forebrain
Fri Sep 01 00:00:00 UTC 1995
HuD, a paraneoplastic encephalomyelitis antigen, contains RNA-binding domains and is homologous to Elav and Sex-lethal.
Cell
Szabo A,Dalmau J,Manley G,Rosenfeld M,Wong E,Henson J,Posner JB,Furneaux HM
A-21271 was used in western blot to use antibody-associated paraneoplastic encephalomyelitis patient sera to identify a neuronal antigen HuD
Fri Oct 18 00:00:00 UTC 1991
