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          • Primary Antibodies ›
          • IARS Antibodies

          Proteintech

          IARS Polyclonal Antibody

          4 References
          View all (9) IARS antibodies

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          Cite IARS Polyclonal Antibody

          • Antibody Testing Data (8)
          IARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          IARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          IARS Antibody (26942-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 26942-1-AP (IARS Antibody) at dilution of 1:200 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          IARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IARS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          IARS Antibody in Western Blot (WB)
          IARS Antibody in Western Blot (WB)
          IARS Antibody in Western Blot (WB)
          IARS Antibody in Immunoprecipitation (IP)

          Product Details

          26942-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:4,000
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          IARS Fusion Protein Ag25686

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.33 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Target Information

          IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: FLJ20736; IRS; isoleucine tRNA ligase 1, cytoplasmic; Isoleucine--tRNA ligase, cytoplasmic; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic

          View more View less

          Gene Aliases: IARS; IARS1; ILERS; ILRS; IRS; PRO0785

          View more View less

          UniProt ID: (Human) P41252

          View more View less

          Entrez Gene ID: (Human) 3376

          View more View less

          Function(s)
          tRNA binding aminoacyl-tRNA editing activity isoleucine-tRNA ligase activity protein binding ATP binding GTPase binding
          Process(es)
          osteoblast differentiation tRNA aminoacylation for protein translation isoleucyl-tRNA aminoacylation regulation of translational fidelity
          It has to be done as per old AB suggested Products section.
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