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Abnova
IARS Polyclonal Antibody, MaxPab™
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Product Details
H00003376-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IARS (AAH65552.1, 1 a.a. approximately 1055 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MESVWWVFKQ LYDKGLVYRG VKVMPFSTAC NTPLSNFESH QNYKDVQDPS VFVTFPLEED ETVSLVAWTT TPWTLPSNLA VCVNPEMQYV KIKDVARGRL LILMEARLSA LYKLESDYEI LERFPGAYLK GKKYRPLFDY FLKCKENGAF TVLVDNYVKE EEGTGVVHQA PYFGAEDYRV CMDFNIIRKD SLPVCPVDAS GCFTTEVTDF AGQYVKDADK SIIRTLKEQG RLLVATTFTH SYPFCWRSDT PLIYKAVPSW FVRVENMVDQ LLRNNDLCYW VPELVREKRF GNWLKDARDW TISRNRYWGT PIPLWVSDDF EEVVCIGSVA ELEELSGAKI SDLHRESVDH LTIPSRCGKG SLHRISEVFD CWFESGSMPY AQVHYPFENK REFEDAFPAD FIAEGIDQTR GWFYTLLVLA TALFGQPPFK NVIVNGLVLA SDGQKMSKRK KNYPDPVSII QKYGADALRL YLINSPVVRA ENLRFKEEGV RDVLKDVLLP WYNAYRFLIQ NVLRLQKEEE IEFLYNENTV RESPNITDRW ILSFMQSLIG FFETEMAAYR LYTVVPRLVK FVDILTNWYV RMNRRRLKGE NGMEDCVMAL ETLFSVLLSL CRLMAPYTPF LTELMYQNLK VLIDPVSVQD KDTLSIHYLM LPRVREELID KKTESAVSQM QSVIELGRVI RDRKTIPIKY PLKEIVVIHQ DPEALKDIKS LEKYIIEELN VRKVTLSTDK NKYGIRLRAE PDHMVLGKRL KGAFKAVMTS IKQLSSEELE QFQKTGTIVA EGHELHDEDI RLMYTFDQAT GGTAQFEAHS DAQALVLLDV TPDQSMVDEG MAREVINRIQ KLRKKCNLVP TDEITVYYKA KSEGTYLNSV IESHTEFIFT TIKAPLKPYP VSPSDKVLIQ EKTQLKGSEL EITLTRGSSL PGPACAYVNL NICANGSEQG GVLLLENPKG SAPSLINSSS TLLCQYINLQ LLNAKPQECL MGTVGTLLLE NPLGQNGLTH QGLLYEAAKV FGLRSRKLKL FLNETQTQEI TEDIPVKTLN MKTVYVSVLP TTADF
Target Information
IARS is a member of aminoacyl-tRNA synthetases which catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ20736; IRS; isoleucine tRNA ligase 1, cytoplasmic; Isoleucine--tRNA ligase, cytoplasmic; Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase, cytoplasmic
Gene Aliases: IARS; IARS1; ILERS; ILRS; IRS; PRO0785
UniProt ID: (Human) P41252
Entrez Gene ID: (Human) 3376
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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