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Invitrogen
IBTK Polyclonal Antibody
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Product Details
PA5-103366
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IBTK(Accession Q9P2D0), corresponding to amino acid residues V1224-T1274.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852710
Product Specific Information
Antibody detects endogenous levels of total IBTK.
Target Information
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bruton agammaglobulinemia tyrosine kinase inhibitor; BTK-binding protein; IBtk; Inhibitor of Bruton tyrosine kinase; inhibitor of Bruton's tyrosine kinase-alpha; inhibitor of Bruton's tyrosine kinase-beta; inhibitor of Bruton's tyrosine kinase-gamma; RP1-93K22.1
Gene Aliases: BTBD26; BTKI; IBTK; KIAA1417
UniProt ID: (Human) Q9P2D0
Entrez Gene ID: (Human) 25998
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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