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Product Details
PA5-65337
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human ICAT. Recombinant protein control fragment (Product #RP-106032).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2664918
Product Specific Information
Immunogen sequence: MNREGAPGKSP EEMYIQQKVR VLLMLRKMGS NLTASEEEFL RTYAGVVNSQ LSQLPPHSID QGAEDVVMAF SRSETEDRR
Highest antigen sequence identity to the following orthologs - mouse 98%, rat 99%.
Target Information
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; catenin; catenin, beta interacting protein 1; Inhibitor of beta-catenin and Tcf-4
Gene Aliases: CTNNBIP1; ICAT
UniProt ID: (Human) Q9NSA3
Entrez Gene ID: (Human) 56998
branching involved in ureteric bud morphogenesis
regulation of vascular permeability involved in acute inflammatory response
anterior/posterior pattern specification
Wnt signaling pathway
negative regulation of Wnt signaling pathway
negative regulation of protein binding
negative regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of monocyte differentiation
positive regulation of osteoblast differentiation
negative regulation of smooth muscle cell proliferation
negative regulation of transcription initiation from RNA polymerase II promoter
negative regulation of mesenchymal cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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