Proteintech

IDI1 Polyclonal Antibody

FIGURE: 1 / 5

IDI1 Antibody (11166-2-AP) in WB

Mouse liver tissue were subjected to SDS PAGE followed by western blot with 11166-2-AP (IDI1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

IDI1 Antibody in Immunoprecipitation (IP)

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Product Details

11166-2-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

View 5 publications 5 publications

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

IDI1 Fusion Protein Ag1636 (1-237 aa encoded by BC019227)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.23 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: VLEQIRHFV MMPEINTNHL DKQQVQLLAE MCILIDENDN KIGAETKKNC HLNENIEKGL LHRAFSVFLF NTENKLLLQQ RSDAKITFPG CFTNTCCSHP LSNPAELEES DTLGVRRAAQ RRLKAELGIP LEEVPPEEIN YLTRIHYKAQ SDGIWGEHEI DYILLVRKNV TLNPDPNEIK SYCYVSKEEL KELLKKAASG EIKITPWFKI IAATFLFKWW DNLNHLNQFV DHEKIYRM (1-237 aa encoded by BC019227)

Target Information

IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Sinapic and ferulic acid phenethyl esters increase the expression of steroidogenic genes in MA-10 tumor Leydig cells.

Toxicology in vitro : an international journal published in association with BIBRA

Basque A,Touaibia M,Martin LJ

Wed Feb 01 00:00:00 UTC 2023

Gigantol Improves Cholesterol Metabolism and Progesterone Biosynthesis in MA-10 Leydig Cells.

Current issues in molecular biology

Basque A,Nguyen HT,Touaibia M,Martin LJ

Thu Dec 23 00:00:00 UTC 2021

Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory.

Neuron

Li X,Zhang J,Li D,He C,He K,Xue T,Wan L,Zhang C,Liu Q

Wed Mar 17 00:00:00 UTC 2021

Utilizing Optimized Tools to Investigate PTM Crosstalk: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins.

Proteomes

Horita H,Law A,Middleton K

Tue May 22 00:00:00 UTC 2018

Utilizing Optimized Tools to Investigate PTM Crosstalk: Identifying Potential PTM Crosstalk of Acetylated Mitochondrial Proteins.

Proteomes

Horita H,Law A,Middleton K

Tue May 22 00:00:00 UTC 2018

Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress.

PloS one

King FW,Fong S,Griffin C,Shoemaker M,Staub R,Zhang YL,Cohen I,Shtivelman E

Wed Sep 30 00:00:00 UTC 2009

Timosaponin AIII is preferentially cytotoxic to tumor cells through inhibition of mTOR and induction of ER stress.

PloS one

King FW,Fong S,Griffin C,Shoemaker M,Staub R,Zhang YL,Cohen I,Shtivelman E

Wed Sep 30 00:00:00 UTC 2009

Bioinformatics

Protein Aliases: IPP isomerase 1; IPPI1; isopentenyl diphosphate dimethylallyl diphosphate isomerase 1; Isopentenyl pyrophosphate isomerase 1; Isopentenyl-diphosphate Delta-isomerase 1

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Gene Aliases: 4832416K17Rik; IDI1; IPP1; IPPI1

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UniProt ID: (Human) Q13907, (Rat) O35760, (Mouse) P58044

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Entrez Gene ID: (Human) 3422, (Rat) 89784, (Mouse) 319554

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Function(s)

isopentenyl-diphosphate delta-isomerase activity hydrolase activity metal ion binding magnesium ion binding manganese ion binding

Process(es)

cholesterol biosynthetic process isoprenoid biosynthetic process response to stilbenoid dimethylallyl diphosphate biosynthetic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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IDI1 Polyclonal Antibody

IDI1 Antibody (11166-2-AP) in WB

Product Details

11166-2-AP

Western Blot (WB)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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