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Rockland
IDN3 Polyclonal Antibody
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FIGURE: 1 / 2
IDN3 Antibody (600-101-288) in WB
Western blot using Rocklands Affinity Purified anti-IDN3 antibody shows detection of a band ~300 kDa corresponding to IDN3 (arrowhead) in human kidney (lane 1) and human heart (lane 2) whole cell tissue extracts. Approximately 20µg of each lysate was separated by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:500. Use HRP conjugated Rb-a-Goat IgG [H&L] MXHu (605-403-013) for detection.
Product Details
600-101-288
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
This affinity-purified antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 330-365 of Human IDN3.
Conjugate
Form
Liquid
Concentration
1.6 mg/mL
Purification
Affinity chromatography
Storage buffer
0.02M potassium phosphate, pH 7.2, with 0.15M NaCl
Contains
0.01% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
This affinity purified antibody is directed against human IDN3 protein. A BLAST analysis was used to suggest reactivity with this protein from human, rat, mouse, dog, bovine and orangutan based on 100% homology for the immunogen sequence. Expect reactivity with multiple splice variants of this protein. Cross reactivity with IDN3 homologues from other sources has not been determined.
Target Information
Probably plays a structural role in chromatin. Involved in sister chromatid cohesion, possibly by interacting with the cohesin complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Delangin; DKFZp434L1319; FLJ11203; FLJ12597; FLJ13354; FLJ13648; Nipped-B homolog; Nipped-B-like protein; SCC2 homolog; sister chromatid cohesion 2 homolog
Gene Aliases: CDLS; CDLS1; IDN3; IDN3-B; NIPBL; SCC2
UniProt ID: (Human) Q6KC79
Entrez Gene ID: (Human) 25836
negative regulation of transcription from RNA polymerase II promoter
metanephros development
heart morphogenesis
outflow tract morphogenesis
cellular response to DNA damage stimulus
mitotic sister chromatid cohesion
brain development
sensory perception of sound
stem cell population maintenance
positive regulation of histone deacetylation
maintenance of mitotic sister chromatid cohesion
cellular protein localization
embryonic forelimb morphogenesis
forelimb morphogenesis
external genitalia morphogenesis
positive regulation of multicellular organism growth
ear morphogenesis
regulation of hair cycle
fat cell differentiation
positive regulation of ossification
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of embryonic development
embryonic digestive tract morphogenesis
developmental growth
eye morphogenesis
regulation of developmental growth
embryonic viscerocranium morphogenesis
cognition
face morphogenesis
gall bladder development
uterus morphogenesis
cellular response to X-ray
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