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Immunogen sequence: IAVLHEERFL KNIGWGTDQG IGGFGEEPGI KSQLMNLIRS VRT
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.
This gene encodes a small protein that is localized to the endoplasmic reticulum (ER) and may play a role in the ER stress response by mediating cell differentiation and apoptosis. Transcription of this gene is regulated by tumor necrosis factor alpha and specificity protein 1 (Sp1). Mutations in this gene may play a role in microcephaly, epilepsy, and diabetes syndrome (MEDS), and a pseudogene of this gene is located on the long arm of chromosome 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IER3IP1; Immediate early response 3-interacting protein 1
Gene Aliases: HSPC039; IER3IP1; MEDS; PRO2309
UniProt ID: (Human) Q9Y5U9
Entrez Gene ID: (Human) 51124
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