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Invitrogen
IFI27 Polyclonal Antibody
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IFI27 Antibody (PA5-103440) in IHC (P)
Immunohistochemistry analysis of IFI27 in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with IFI27 polyclonal antibody (Product # PA5-103440) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-103440
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IFI27(Accession P40305), corresponding to amino acid residues M1-I33.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852781
Product Specific Information
Antibody detects endogenous levels of total IFI27.
Target Information
Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2310061N23Rik; Interferon alpha-induced 11.5 kDa protein; interferon alpha-inducible protein 27; Interferon alpha-inducible protein 27, mitochondrial; interferon, alpha-inducible protein 27; interferon, alpha-inducible protein 27 like 1; interferon, alpha-inducible protein 27-like; Interferon-stimulated gene 12a protein; ISG12(a); p27; putative ISG12(a) protein
Gene Aliases: 1110013J02Rik; 2900026P10Rik; D12Ertd647e; FAM14D; IFI27; Ifi27l; Ifi27l1; IRG1; ISG12; isg12(a); ISG12A; P27
UniProt ID: (Human) P40305
Entrez Gene ID: (Human) 3429, (Rat) 170512, (Mouse) 52668
negative regulation of transcription from RNA polymerase II promoter
activation of cysteine-type endopeptidase activity involved in apoptotic process
response to estradiol
response to cytokine
regulation of protein export from nucleus
maternal process involved in female pregnancy
apoptotic signaling pathway
type I interferon signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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