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Immunogen sequence: ALEYIPNNAY LHCQIGCCYR AKVFQVMNLR ENGMYGKRKL LELIGHAVAH LKKADEANDN LFRVCSILAS LHALADQYED AEYYFQKEFS KELTPVAKQL LHLRYGNFQL YQMKCEDKAI HHFIEGVKIN QKSREKEKMK DKLQKIAKMR LSKNGADSEA LHVLAFLQEL NEKMQQADED SERGLESGSL IPSASSWNGE; Positive Samples: A-431, HepG2; Cellular Location: Cytoplasm, Endoplasmic reticulum
IFIT2 belongs to the IFIT family. It contains 6 TPR repeats. IFIT genes comprise a large family with three (Ifit1, Ifit2, and Ifit3) and four (IFIT1, IFIT2, IFIT3, and IFIT5) members in mice and humans, respectively. IFITproteins are produced in human body that are supposed to confer immunity against viral infection. These proteins are generally produced during viral infection, Interferon (IFN) treatment, and during pathogen recognition (Pathogen associated molecular pattern recognition) byimmune systemduring infections.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IFI-54K; IFIT-2; Interferon, alpha-inducible protein (MW 54kD); Interferon-induced 54 kDa protein; interferon-induced protein 54; Interferon-induced protein with tetratricopeptide repeats 2; ISG-54 K
Gene Aliases: CIG-42; cig42; G10P2; GARG-39; IFI-54; IFI-54K; IFI54; IFIT-2; IFIT2; ISG-54 K; ISG-54K; ISG54; P54
UniProt ID: (Human) P09913
Entrez Gene ID: (Human) 3433
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