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Proteintech
IFITM2 Polyclonal Antibody, CoraLite® Plus 488
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FIGURE: 1 / 1
IFITM2 Antibody (CL48812769100UL) in Flow
1X10^6 MCF-7 cells were intracellularly stained with 0.4 µg CoraLite 488 Anti-Human IFITM2 (Product # CL48812769100UL)) (red), or 0.4 µg Control Antibody. Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C).
Product Details
CL48812769100UL
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Wet ice
Target Information
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein-mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dispanin subfamily A member 2c; DSPA2c; Fragilis protein 3; fragilis R; ifm2; interferon induced transmembrane protein, like; Interferon-induced transmembrane protein 2; Interferon-inducible protein 1-8D
Gene Aliases: 1-8D; DSPA2c; fragilis3; IFITM2; Ifitm3l; mil-3
UniProt ID: (Human) Q01629, (Mouse) Q99J93
Entrez Gene ID: (Human) 10581, (Mouse) 80876
immune system process
response to biotic stimulus
response to virus
response to interferon-gamma
response to interferon-alpha
response to interferon-beta
negative regulation of viral genome replication
innate immune response
negative regulation of viral entry into host cell
defense response to virus
immune response
type I interferon signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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