Product References
Use of phage display biopanning as a tool to design CAR-T cells against glioma stem cells.
Frontiers in oncology
Potez M,Snedal S,She C,Kim J,Thorner K,Tran TH,Ramello MC,Abate-Daga D,Liu JKC
M700A was used in ELISA to exemplify the use of phage display biopanning for the isolation of GSC-targeting peptides, and their potential application in the development of novel cytotoxic therapies for glioblastoma (GBM).
Wed Dec 27 00:00:00 UTC 2023
γδ-Enriched CAR-T cell therapy for bone metastatic castrate-resistant prostate cancer.
Science advances
Frieling JS,Tordesillas L,Bustos XE,Ramello MC,Bishop RT,Cianne JE,Snedal SA,Li T,Lo CH,de la Iglesia J,Roselli E,Benzaïd I,Wang X,Kim Y,Lynch CC,Abate-Daga D
M700A was used in ELISA to report a combinatorial strategy to treat bone metastatic castrate-resistant prostate cancer using γδ-enriched chimeric antigen receptor (CAR) T cells and zoledronate (ZOL).
Wed May 03 00:00:00 UTC 2023
Identification and assessment of TCR-T cells targeting an epitope conserved in SARS-CoV-2 variants for the treatment of COVID-19.
International immunopharmacology
Ma Y,Liu F,Li B,Peng K,Zhou H,Xu Y,Qiao D,Deng L,Tian G,Nielsen M,Wang M
M700A was used in Enzyme-linked immunosorbent assay to identify two TCRs targeting the RNA-dependent RNA polymerase (RdRp) protein in CD8 + T cells.
Tue Nov 01 00:00:00 UTC 2022
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy.
Journal for immunotherapy of cancer
Liu X,Xu Y,Xiong W,Yin B,Huang Y,Chu J,Xing C,Qian C,Du Y,Duan T,Wang HY,Zhang N,Yu JS,An Z,Wang R
M700A was used in ELISA to investigate developping antibodies against T cell receptors.
Tue Mar 01 00:00:00 UTC 2022
IL-15 superagonist N-803 improves IFNγ production and killing of leukemia and ovarian cancer cells by CD34+ progenitor-derived NK cells.
Cancer immunology, immunotherapy : CII
Van der Meer JMR,Maas RJA,Guldevall K,Klarenaar K,de Jonge PKJD,Evert JSH,van der Waart AB,Cany J,Safrit JT,Lee JH,Wagena E,Friedl P,Önfelt B,Massuger LF,Schaap NPM,Jansen JH,Hobo W,Dolstra H
M700A was used in an ELISA assay to investigate whether and how N-803 improves HPC-NK cell functionality in leukemia and ovarian cancer (OC) models in vitro and in vivo in OC-bearing immunodeficient mice.
Sat May 01 00:00:00 UTC 2021
PD-L1 on mast cells suppresses effector CD8+ T-cell activation in the skin in murine contact hypersensitivity.
The Journal of allergy and clinical immunology
Hirano T,Honda T,Kanameishi S,Honda Y,Egawa G,Kitoh A,Nakajima S,Otsuka A,Nomura T,Dainichi T,Yaguchi T,Inozume T,Kataoka TR,Tamada K,Kabashima K
M700A was used in ELISA to show that PD-L1 on radioresistant cells was responsible for this regulatory pathway.
Sun Aug 01 00:00:00 UTC 2021
Preformed donor-reactive T cells that persist after ABO desensitization predict severe T cell-mediated rejection after living donor kidney transplantation - a retrospective study.
Transplant international : official journal of the European Society for Organ Transplantation
Schachtner T,Stein M,Otto NM,Reinke P
M700A was used in ELISA to analyze 150 living donor kidney transplant recipients (KTRs) of a first kidney allograft.
Sun Mar 01 00:00:00 UTC 2020
Evaluation of Single-Cell Cytokine Secretion and Cell-Cell Interactions with a Hierarchical Loading Microwell Chip.
Cell reports
Zhou Y,Shao N,Bessa de Castro R,Zhang P,Ma Y,Liu X,Huang F,Wang RF,Qin L
M700A was used in MISC TSA ASSAY to develop a hierarchical loading microwell chip (HL-Chip) that is capable of efficiently aligning multiple cells of different types and/or microbeads as desired in a highthroughput manner.
Tue Apr 28 00:00:00 UTC 2020
Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis.
Autophagy
Takagaki Y,Lee SM,Dongqing Z,Kitada M,Kanasaki K,Koya D
M700A was used in Western Blotting to demonstrate that autophagy defects in endothelial cells induced IL6 (interleukin 6)-dependent endothelial-to-mesenchymal transition (EndMT) and organ fibrosis with metabolic defects in mice.
Thu Oct 01 00:00:00 UTC 2020
Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis.
Autophagy
Takagaki Y,Lee SM,Dongqing Z,Kitada M,Kanasaki K,Koya D
M700A was used in Western Blotting to demonstrate that autophagy defects in endothelial cells induced IL6 (interleukin 6)-dependent endothelial-to-mesenchymal transition (EndMT) and organ fibrosis with metabolic defects in mice.
Thu Oct 01 00:00:00 UTC 2020
Selection of a Clinical Lead TCR Targeting Alpha-Fetoprotein-Positive Liver Cancer Based on a Balance of Risk and Benefit.
Frontiers in immunology
Luo X,Cui H,Cai L,Zhu W,Yang WC,Patrick M,Zhu S,Huang J,Yao X,Yao Y,He Y,Ji Y
M700A was used in an ELISA assay to evaluate the efficacy and safety profile of 7 TCRs by testing their potency toward AFP-expressing HCC cells and their specificity based upon reactivity to normal and transformed cells covering a wide variety of primary cell types and HLA serotypes.
Mon Mar 29 00:00:00 UTC 2021
Runx-mediated regulation of CCL5 via antagonizing two enhancers influences immune cell function and anti-tumor immunity.
Nature communications
Seo W,Shimizu K,Kojo S,Okeke A,Kohwi-Shigematsu T,Fujii SI,Taniuchi I
M700A was used in ELISA to suggest that RUNX3-mediated CCL5 repression is critical for modulating anti-tumor immunity.
Thu Mar 26 00:00:00 UTC 2020
Molecular affinity rulers: systematic evaluation of DNA aptamers for their applicabilities in ELISA.
Nucleic acids research
Kimoto M,Shermane Lim YW,Hirao I
M700A was used in Miscellaneous to develop molecular affinity rulers: two sets of Ds-DNA aptamer variants with a diverse range of affinities to the same area on the target proteins.
Thu Sep 19 00:00:00 UTC 2019
A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation.
The Journal of experimental medicine
Fernandez IZ,Baxter RM,Garcia-Perez JE,Vendrame E,Ranganath T,Kong DS,Lundquist K,Nguyen T,Ogolla S,Black J,Galambos C,Gumbart JC,Dawany N,Kelsen JR,de Zoeten EF,Quinones R,Eissa H,Verneris MR,Sullivan KE,Rochford R,Blish CA,Kedl RM,Dutmer CM,Hsieh EWY
M700A was used in ELISPOT to investigate the clinical and immunological phenotypes of two siblings with the first described human IL-2Rβ defect.
Mon Jun 03 00:00:00 UTC 2019
Soluble Fc-Disabled Herpes Virus Entry Mediator Augments Activation and Cytotoxicity of NK Cells by Promoting Cross-Talk between NK Cells and Monocytes.
Journal of immunology (Baltimore, Md. : 1950)
Meng Q,Zaidi AK,Sedy J,Bensussan A,Popkin DL
M700A was used in an ELISA assay to evaluate the specific function of herpes virus entry mediator (HVEM) in regulating CD160-mediated NK cell effector function.
Mon Apr 01 00:00:00 UTC 2019
Transplantectomy is associated with presensitization with donor-reactive T cells and graft failure after kidney retransplantation: a cohort study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Schachtner T,Otto NM,Stein M,Reinke P
M700A was used in an ELISpot assay to suggest higher cellular presensitization among KTRs with the previous allograft removed, which is associated with higher rates of acute cellular rejection and inferior allograft survival.
Tue May 01 00:00:00 UTC 2018
Differential T cell response against BK virus regulatory and structural antigens: A viral dynamics modelling approach.
PLoS computational biology
Blazquez-Navarro A,Schachtner T,Stervbo U,Sefrin A,Stein M,Westhoff TH,Reinke P,Klipp E,Babel N,Neumann AU,Or-Guil M
M700A was used in an ELISpot assay to study the influence of different modes of action of the cellular immune response on BK virus clearance dynamics.
Tue May 01 00:00:00 UTC 2018
Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.
Cell chemical biology
Chennamadhavuni D,Saavedra-Avila NA,Carreño LJ,Guberman-Pfeffer MJ,Arora P,Yongqing T,Pryce R,Koay HF,Godfrey DI,Keshipeddy S,Richardson SK,Sundararaj S,Lo JH,Wen X,Gascón JA,Yuan W,Rossjohn J,Le Nours J,Porcelli SA,Howell AR
M700A was used in an ELISA assay to demonstrate that strongly proinflammatory and anti-tumour invariant natural killer T cell responses are achieved in mice by a variant of α-galactosylceramide.
Thu May 17 00:00:00 UTC 2018
Different Lipid Regulation in Ovarian Cancer: Inhibition of the Immune System.
International journal of molecular sciences
Wefers C,Duiveman-de Boer T,Zusterzeel PLM,Massuger LFAG,Fuchs D,Torensma R,Wheelock CE,de Vries IJM
Wed Jan 17 00:00:00 UTC 2018
Identification of essential genes for cancer immunotherapy.
Nature
Patel SJ,Sanjana NE,Kishton RJ,Eidizadeh A,Vodnala SK,Cam M,Gartner JJ,Jia L,Steinberg SM,Yamamoto TN,Merchant AS,Mehta GU,Chichura A,Shalem O,Tran E,Eil R,Sukumar M,Guijarro EP,Day CP,Robbins P,Feldman S,Merlino G,Zhang F,Restifo NP
M700A was used in an ELISA assay to show that APLNR interacts with JAK1, modulating interferon-γ responses in tumours, and that its functional loss reduces the efficacy of immunotherapies in mouse models.
Thu Aug 31 00:00:00 UTC 2017
De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy.
Clinical immunology (Orlando, Fla.)
Mufarrege EF,Giorgetti S,Etcheverrigaray M,Terry F,Martin W,De Groot AS
M700A was used in ELISA to develop and characterize a functional and de-immunized version of hyperglycosylated interferon alpha
Wed Mar 01 00:00:00 UTC 2017
Epitope mapping reveals the binding mechanism of a functional antibody cross-reactive to both human and murine programmed death 1.
mAbs
Li D,Xu J,Wang Z,Gong Z,Liu J,Zheng Y,Li J,Li J
M700A was used in an ELISA assay to compare the epitopes of an antibody, functional against both human and murine PD-1, to a counterpart that only bound to hPD-1.
Tue Feb 20 00:00:00 UTC 2018
Sepsis after renal transplantation: Clinical, immunological, and microbiological risk factors.
Transplant infectious disease : an official journal of the Transplantation Society
Schachtner T,Stein M,Reinke P
M700A was used in Enzyme-linked immunosorbent assay to identify 112 of 957 kidney transplant recipients (KTRs) with sepsis.
Thu Jun 01 00:00:00 UTC 2017
Elevated levels of polymorphonuclear myeloid-derived suppressor cells in patients with glioblastoma highly express S100A8/9 and arginase and suppress T cell function.
Neuro-oncology
Gielen PR,Schulte BM,Kers-Rebel ED,Verrijp K,Bossman SA,Ter Laan M,Wesseling P,Adema GJ
M700A was used in ELISA to discuss the role of myeloid-derived suppressor cells in gliomas
Thu Sep 01 00:00:00 UTC 2016
Autoreactive T Cells from Patients with Myasthenia Gravis Are Characterized by Elevated IL-17, IFN-γ, and GM-CSF and Diminished IL-10 Production.
Journal of immunology (Baltimore, Md. : 1950)
Cao Y,Amezquita RA,Kleinstein SH,Stathopoulos P,Nowak RJ,O'Connor KC
M700A was used in ELISA to examine the contribution of T cells to myasthenia gravis
Tue Mar 01 00:00:00 UTC 2016
Virtual Global Transplant Laboratory Standard Operating Protocol for Donor Alloantigen-specific Interferon-gamma ELISPOT Assay.
Transplantation direct
Carroll R,Troelnikov A,Chong AS
M700A was used in ELISA to discuss the use of an ELISPOT assay to detect IFN-gamma-producing T cells for pretransplant and posttransplant immunological risk stratification
Tue Nov 01 00:00:00 UTC 2016
TLR7 induces anergy in human CD4(+) T cells.
Nature immunology
Dominguez-Villar M,Gautron AS,de Marcken M,Keller MJ,Hafler DA
M700A was used in ELISA to examine the role of TLR7 in HIV-infected CD4 positive T cells.
Thu Jan 01 00:00:00 UTC 2015
Bee venom processes human skin lipids for presentation by CD1a.
The Journal of experimental medicine
Bourgeois EA,Subramaniam S,Cheng TY,De Jong A,Layre E,Ly D,Salimi M,Legaspi A,Modlin RL,Salio M,Cerundolo V,Moody DB,Ogg G
M700A was used in ELISA to test if venoms contain CD1-presented antigens
Mon Feb 09 00:00:00 UTC 2015
Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis.
Science translational medicine
Das S,Freier A,Boussoffara T,Das S,Oswald D,Losch FO,Selka M,Sacerdoti-Sierra N,Schönian G,Wiesmüller KH,Seifert K,Schroff M,Juhls C,Jaffe CL,Roy S,Das P,Louzir H,Croft SL,Modabber F,Walden P
M700A was used in ELISA to develop a DNA vaccine against human leishmaniasis that induces T-cell immunity
Wed Apr 30 00:00:00 UTC 2014
Tremella Polysaccharides attenuated sepsis through inhibiting abnormal CD4⁺CD25(high) regulatory T cells in mice.
Cellular immunology
Shi ZW,Liu Y,Xu Y,Hong YR,Liu Q,Li XL,Wang ZG
M700A was used in ELISA to study the role of CD4(+)/CD25(high) T-reg cell inhibition in the therapeutic effects of Tremalla polysaccharides in a murine burn model of sepsis
Thu May 29 00:00:00 UTC 2014
Differential influenza H1N1-specific humoral and cellular response kinetics in kidney transplant patients.
Medical microbiology and immunology
Rambal V,Müller K,Dang-Heine C,Sattler A,Dziubianau M,Weist B,Luu SH,Stoyanova A,Nickel P,Thiel A,Neumann A,Schweiger B,Reinke P,Babel N
M700A was used in ELISA to compare the rate of activation of adaptive immunity by the H1N1 influena virus in kidney transplant patients as compared to healthy individuals
Sat Feb 01 00:00:00 UTC 2014
Inflammatory activation and recovering BKV-specific immunity correlate with self-limited BKV replication after renal transplantation.
Transplant international : official journal of the European Society for Organ Transplantation
Schachtner T,Stein M,Sefrin A,Babel N,Reinke P
M700A was used in ELISA to study BKV-associated nephropathy following kidney transplant and the clinical significance of recovering BKV-specific immunity and inflammatory activation
Sat Mar 01 00:00:00 UTC 2014
Innate immune control of EBV-infected B cells by invariant natural killer T cells.
Blood
Chung BK,Tsai K,Allan LL,Zheng DJ,Nie JC,Biggs CM,Hasan MR,Kozak FK,van den Elzen P,Priatel JJ,Tan R
M700A was used in ELISA to study the role of invariant NK T-cells in innate immune control of B-cell EBV infection
Thu Oct 10 00:00:00 UTC 2013
The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans.
Journal of immunology (Baltimore, Md. : 1950)
Lozano E,Joller N,Cao Y,Kuchroo VK,Hafler DA
M700A was used in ELISA to study the role of the interaction between CD226 and CD155 in regulating the human T-cell pro-inflammatory/anti-inflammatory balance
Tue Oct 01 00:00:00 UTC 2013
An HLA-modified ovarian cancer cell line induced CTL responses specific to an epitope derived from claudin-1 presented by HLA-A*24:02 molecules.
Human immunology
Kondo S,Demachi-Okamura A,Hirosawa T,Maki H,Fujita M,Uemura Y,Akatsuka Y,Yamamoto E,Shibata K,Ino K,Kikkawa F,Kuzushima K
M700A was used in ELISA to study the ability of a HLA-modified ovarian cancer cell line to induce cytotoxic T-cell responses to a HLA-presented claudin-1 epitope
Sun Sep 01 00:00:00 UTC 2013
Imaging of Protein Secretion from a Single Cell Using Plasmonic Substrates.
BioNanoScience
Szmacinski H,Toshchakov V,Piao W,Lakowicz JR
M700A was used in Immunocytochemistry-immunoflourescence to develop substrates with plasmonic nanoparticles and fluorescence microscopy as promising imaging methods for studies on molecular processes controlling cell behaviour, particularly secretion of cytokines.
Fri Mar 01 00:00:00 UTC 2013
Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells.
PloS one
Rodriguez ME,Loyd CM,Ding X,Karim AF,McDonald DJ,Canaday DH,Rojas RE
M700A was used in ELISA to test the effect of different Mycobacterium tuberculosis molecules on HIV-1 replication
Tue Aug 05 00:00:00 UTC 2014
Long-term proliferation of functional human NK cells, with conversion of CD56(dim) NK cells to a CD56 (bright) phenotype, induced by carcinoma cells co-expressing 4-1BBL and IL-12.
Cancer immunology, immunotherapy : CII
Dowell AC,Oldham KA,Bhatt RI,Lee SP,Searle PF
M700A was used in ELISA to investigate the influence of 4-1BBL and interleukin 12 on the proliferation of NK cells
Tue May 01 00:00:00 UTC 2012
Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells.
Journal of immunology (Baltimore, Md. : 1950)
Yaguchi T,Goto Y,Kido K,Mochimaru H,Sakurai T,Tsukamoto N,Kudo-Saito C,Fujita T,Sumimoto H,Kawakami Y
M700A was used in ELISA to study the role of human melanoma cell Wnt/beta-catenin signaling in immune suppression and resistance
Sat Sep 01 00:00:00 UTC 2012
Chemically programmed bispecific antibodies that recruit and activate T cells.
The Journal of biological chemistry
Cui H,Thomas JD,Burke TR,Rader C
M700A was used in ELISA to develop and validate novel bispecific antibodies that activate and direct T-cells against tumor cells
Fri Aug 17 00:00:00 UTC 2012
Human atopic dermatitis complicated by eczema herpeticum is associated with abnormalities in IFN-γ response.
The Journal of allergy and clinical immunology
Leung DY,Gao PS,Grigoryev DN,Rafaels NM,Streib JE,Howell MD,Taylor PA,Boguniewicz M,Canniff J,Armstrong B,Zaccaro DJ,Schneider LC,Hata TR,Hanifin JM,Beck LA,Weinberg A,Barnes KC
M700A was used in ELISA to study whether aberrant IFNgamma responses play a role in the susceptibility of atopic dermatitis patients to eczema herpeticum
Fri Apr 01 00:00:00 UTC 2011
BK virus-specific immunity kinetics: a predictor of recovery from polyomavirus BK-associated nephropathy.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Schachtner T,Müller K,Stein M,Diezemann C,Sefrin A,Babel N,Reinke P
M700A was used in ELISA to investigate the effectiveness of BKV-specific immunity detection for the diagnosis and treatment of BKV-associated nephropathy
Tue Nov 01 00:00:00 UTC 2011
Wildtype p53-specific antibody and T-cell responses in cancer patients.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Pedersen AE,Stryhn A,Justesen S,Harndahl M,Rasmussen S,Donskov F,Claesson MH,Pedersen JW,Wandall HH,Svane IM,Buus S
M700A was used in ELISA to study wild-type p53-specific antibody and T-cell responses in cancer patients
Wed Feb 08 00:00:00 UTC 2012
Antibody and Th1-type cell-mediated immune responses in elderly and young adults immunized with the standard or a high dose influenza vaccine.
Vaccine
Chen WH,Cross AS,Edelman R,Sztein MB,Blackwelder WC,Pasetti MF
M700A was used in ELISA to investigate the humoral and cellular immune responses in elderly and young adults immunized with influenza vaccine
Tue Apr 05 00:00:00 UTC 2011
Clinical allergy to hazelnut and peanut: identification of T cell cross-reactive allergens.
International archives of allergy and immunology
Glaspole IN,de Leon MP,Prickett SR,O'Hehir RE,Rolland JM
M700A was used in ELISA to study the role of T cell cross-reactive allergens in hazelnut and peanut allergy
Fri Sep 30 00:00:00 UTC 2011
Integrated immunoassay using tuneable surface acoustic waves and lensfree detection.
Lab on a chip
Bourquin Y,Reboud J,Wilson R,Zhang Y,Cooper JM
M700A was used in ELISA to develop a novel optoacoustic immunoassay technology for the diagnosis of infectious diseases
Sun Aug 21 00:00:00 UTC 2011
Highly differentiated, resting gn-specific memory CD8+ T cells persist years after infection by andes hantavirus.
PLoS pathogens
Manigold T,Mori A,Graumann R,Llop E,Simon V,Ferrés M,Valdivieso F,Castillo C,Hjelle B,Vial P
M700A was used in ELISA to study the Gn-specific memory CD8+ T cells after Infection by Andes Hantavirus
Fri Feb 19 00:00:00 UTC 2010
Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation.
Immunology
Arimoto-Miyamoto K,Kadowaki N,Kitawaki T,Iwata S,Morimoto C,Uchiyama T
M700A was used in ELISA to study the regulatory mechanism for CD70 induction and its role in T-cell differentiation
Sat May 01 00:00:00 UTC 2010
Fibroblasts stimulated via HLA-II molecules produce prostaglandin E₂ and regulate cytokine production from helper T cells.
Laboratory investigation; a journal of technical methods and pathology
Kato-Kogoe N,Ohyama H,Nishimura F,Meguro M,Yoshizawa S,Okada Y,Nakasho K,Yamanegi K,Yamada N,Hata M,Higashi T,Terada N,Matsushita S
M700A was used in ELISA to study the role of HLA-DQ molecules in Th-cell responses
Wed Dec 01 00:00:00 UTC 2010
Th1 responses to beta-amyloid in young humans convert to regulatory IL-10 responses in Down syndrome and Alzheimer's disease.
Neurobiology of aging
Loewenbrueck KF,Tigno-Aranjuez JT,Boehm BO,Lehmann PV,Tary-Lehmann M
M700A was used in ELISA to study the role of Th1 responses to beta-amyloid in Down syndrome and Alzheimer disease
Fri Oct 01 00:00:00 UTC 2010
Allele specificity of gamma interferon responses to the carboxyl-terminal region of Plasmodium falciparum merozoite surface protein 1 by Kenyan adults with naturally acquired immunity to malaria.
Infection and immunity
Spring MD,Chelimo K,Tisch DJ,Sumba PO,Rochford R,Long CA,Kazura JW,Moormann AM
M700A was used in ELISA to study the mechanism for the protective effect of antibodies against Plasmodium falciparum merozoite surface protein 1
Fri Oct 01 00:00:00 UTC 2010
Inhibition of toxic shock by human monoclonal antibodies against staphylococcal enterotoxin B.
PloS one
Larkin EA,Stiles BG,Ulrich RG
M700A was used in ELISA to study the ability of a number of human monoclonal antibodies against staphylococcal enterotoxin B to block toxic shock
Mon Oct 11 00:00:00 UTC 2010
Apolipoprotein-mediated lipid antigen presentation in B cells provides a pathway for innate help by NKT cells.
Blood
Allan LL,Hoefl K,Zheng DJ,Chung BK,Kozak FK,Tan R,van den Elzen P
M700A was used in ELISA to study an apolipoprotein-mediated pathway for lipid antigen presentation in B cells
Thu Sep 17 00:00:00 UTC 2009
Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells.
Neurology
Kivisäkk P,Healy BC,Viglietta V,Quintana FJ,Hootstein MA,Weiner HL,Khoury SJ
M700A was used in ELISA to investigate the effect of natalizumab treatment for peripheral sequestration of proinflammatory T cells
Tue Jun 02 00:00:00 UTC 2009
Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya.
PLoS medicine
Malhotra I,Dent A,Mungai P,Wamachi A,Ouma JH,Narum DL,Muchiri E,Tisch DJ,King CL
M700A was used in ELISA to study the effect of the prenatal malaria exposure on immune tolerance
Wed Jul 01 00:00:00 UTC 2009
IL-12 delivered intratumorally by multilamellar liposomes reactivates memory T cells in human tumor microenvironments.
Clinical immunology (Orlando, Fla.)
Simpson-Abelson MR,Purohit VS,Pang WM,Iyer V,Odunsi K,Demmy TL,Yokota SJ,Loyall JL,Kelleher RJ,Balu-Iyer S,Bankert RB
M700A was used in ELISA to investigate the role of interleukin-12 delivered intratumorally by multilamellar liposomes for memory T cells induction in human tumor microenvironments
Wed Jul 01 00:00:00 UTC 2009
Recombinant bacillus Calmette-Guérin (BCG) expressing interferon-alpha 2B enhances human mononuclear cell cytotoxicity against bladder cancer cell lines in vitro.
Cancer immunology, immunotherapy : CII
Liu W,O'Donnell MA,Chen X,Han R,Luo Y
M700A was used in ELISA to demonstrate the effect of rBCG-interferon alpha on PBMC cytotoxicity against bladder cancer cells
Thu Oct 01 00:00:00 UTC 2009
Differential effects of hepatitis C virus JFH1 on human myeloid and plasmacytoid dendritic cells.
Journal of virology
Liang H,Russell RS,Yonkers NL,McDonald D,Rodriguez B,Harding CV,Anthony DD
M700A was used in ELISA to study the effects of HCV on the maturation and function of human myeloid and plasmacytoid dendritic cells
Mon Jun 01 00:00:00 UTC 2009
Increased per cell IFN-gamma productivity indicates recent in vivo activation of T cells.
Cellular immunology
Schlingmann TR,Shive CL,Targoni OS,Tary-Lehmann M,Lehmann PV
M700A was used in ELISA to study the increase of interferon gamma production as a marker of T cell activation
Tue Aug 25 00:00:00 UTC 2009
Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: results of a Phase I randomized trial.
Vaccine
Lyke KE,Daou M,Diarra I,Kone A,Kouriba B,Thera MA,Dutta S,Lanar DE,Heppner DG,Doumbo OK,Plowe CV,Sztein MB
M700A was used in ELISA to investigate the effect of the blood stage malaria vaccine apical membrane antigen 1 in Malians
Thu Mar 26 00:00:00 UTC 2009
Immune responses in patients with metastatic renal cell carcinoma treated with dendritic cells pulsed with tumor lysate.
Scandinavian journal of immunology
Soleimani A,Berntsen A,Svane IM,Pedersen AE
M700A was used in ELISA to study the effect of tumor lysate-pulsed autologous dendritic cells on the immune responses of patients with metastatic renal cell carcinoma
Sun Nov 01 00:00:00 UTC 2009
Mycophenolic acid inhibits maturation and function of human dendritic cells and B cells.
Human immunology
Wadia PP,Herrera ND,Abecassis MM,Tambur AR
M700A was used in ELISA to investigate the effect of mycophenolic acid on the maturation and function of human dendritic and B cells
Tue Sep 01 00:00:00 UTC 2009
Systemic inflammatory response and downmodulation of peripheral CD25+Foxp3+ T-regulatory cells in patients undergoing radiofrequency thermal ablation for lung cancer.
Human immunology
Fietta AM,Morosini M,Passadore I,Cascina A,Draghi P,Dore R,Rossi S,Pozzi E,Meloni F
M700A was used in ELISA to study the effect of radiofrequency thermal ablation on inflammatory responses and peripheral CD25+Foxp3+ T-regulatory cells in lung cancer patients
Wed Jul 01 00:00:00 UTC 2009
Immunogenicity of novel DosR regulon-encoded candidate antigens of Mycobacterium tuberculosis in three high-burden populations in Africa.
Clinical and vaccine immunology : CVI
Black GF,Thiel BA,Ota MO,Parida SK,Adegbola R,Boom WH,Dockrell HM,Franken KL,Friggen AH,Hill PC,Klein MR,Lalor MK,Mayanja H,Schoolnik G,Stanley K,Weldingh K,Kaufmann SH,Walzl G,Ottenhoff TH
M700A was used in ELISA to study the Mycobacterium tuberculosis antigen presentation in distinct African population
Sat Aug 01 00:00:00 UTC 2009
Determination of HCV-specific T-cell activity.
Methods in molecular biology (Clifton, N.J.)
Yoon JC,Rehermann B
M700A was used in Functional Assay to describe the common techniques for assessing HCV-specific T-cell activity.
Fri Mar 06 00:00:00 UTC 2009
Temporal stability of naturally acquired immunity to Merozoite Surface Protein-1 in Kenyan adults.
Malaria journal
Dent AE,Chelimo K,Sumba PO,Spring MD,Crabb BS,Moormann AM,Tisch DJ,Kazura JW
M700A was used in ELISA to investigate the immmune response to merozoite surface protein-1 in Kenyans
Thu Jul 16 00:00:00 UTC 2009
Measurement of varicella-zoster virus (VZV)-specific cell-mediated immunity: comparison between VZV skin test and interferon-gamma enzyme-linked immunospot assay.
The Journal of infectious diseases
Sadaoka K,Okamoto S,Gomi Y,Tanimoto T,Ishikawa T,Yoshikawa T,Asano Y,Yamanishi K,Mori Y
M700A was used in ELISA to investigate the reliability of VZV skin test and interferon gamma enzyme-linked immunospot assay for the measurement of varicella-zoster virus-specific cell-mediated immunity
Sat Nov 01 00:00:00 UTC 2008
Epstein-Barr virus nuclear antigen 1-specific CD4+ T cells directly kill Epstein-Barr virus-carrying natural killer and T cells.
Cancer science
Demachi-Okamura A,Ito Y,Akatsuka Y,Tsujimura K,Morishima Y,Takahashi T,Kuzushima K
M700A was used in ELISA to study the effect of Epstein-Barr virus nuclear antigen 1-specific CD4+ T cells in EBV infection
Fri Aug 01 00:00:00 UTC 2008
Lactoferrin, a major defense protein of innate immunity, is a novel maturation factor for human dendritic cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Spadaro M,Caorsi C,Ceruti P,Varadhachary A,Forni G,Pericle F,Giovarelli M
M700A was used in ELISA to study the role of lactoferrin as a novel maturation factor for human dendritic cells
Fri Aug 01 00:00:00 UTC 2008
Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice.
Journal of immunology (Baltimore, Md. : 1950)
Simpson-Abelson MR,Sonnenberg GF,Takita H,Yokota SJ,Conway TF,Kelleher RJ,Shultz LD,Barcos M,Bankert RB
M700A was used in ELISA to investigate the engraftment and expansion of human tumor-derived memory T cells in NOD-scid IL2Rgamma null mice
Thu May 15 00:00:00 UTC 2008
Cerebrospinal fluid cytokine responses in human eosinophilic meningitis associated with angiostrongyliasis.
Journal of the neurological sciences
Intapan PM,Kittimongkolma S,Niwattayakul K,Sawanyawisuth K,Maleewong W
M700A was used in ELISA to study cerebrospinal fluid cytokine levels in human eosinophilic meningitis associated with angiostrongyliasis
Tue Apr 15 00:00:00 UTC 2008
MHC-I-restricted epitopes conserved among variola and other related orthopoxviruses are recognized by T cells 30 years after vaccination.
Archives of virology
Tang ST,Wang M,Lamberth K,Harndahl M,Dziegiel MH,Claesson MH,Buus S,Lund O
M700A was used in ELISA to characterize the long-term epitope recognition for variola and other related orthopoxviruses
Fri Nov 14 00:00:00 UTC 2008
The TRAIL of helpless CD8+ T cells in HIV infection.
AIDS research and human retroviruses
Kuerten S,Asaad RJ,Schoenberger SP,Angelov DN,Lehmann PV,Tary-Lehmann M
M700A was used in ELISA to study the regulation of CD8+ T cell responses in HIV infection by CD4+ T cells
Mon Sep 01 00:00:00 UTC 2008
NKG2D-mediated antitumor activity by tumor-infiltrating lymphocytes and antigen-specific T-cell clones isolated from melanoma patients.
Clinical cancer research : an official journal of the American Association for Cancer Research
Maccalli C,Nonaka D,Piris A,Pende D,Rivoltini L,Castelli C,Parmiani G
M700A was used in ELISA to study the role of NKG2D+ T cells in the immunologic response against tumor
Sat Dec 15 00:00:00 UTC 2007
Exposure to holoendemic malaria results in suppression of Epstein-Barr virus-specific T cell immunosurveillance in Kenyan children.
The Journal of infectious diseases
Moormann AM,Chelimo K,Sumba PO,Tisch DJ,Rochford R,Kazura JW
M700A was used in ELISA to study the effect of holoendemic malaria exposure on the Epstein-Barr virus-specific T cell immunosurveillance in children
Thu Mar 15 00:00:00 UTC 2007
Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells.
Clinical and experimental immunology
Windhagen A,Sönmez D,Hornig-Do HT,Kalinowsky A,Schwinzer R
M700A was used in ELISA to investigate the effect of CD45 isoform expression changes on T cell activity
Sat Dec 01 00:00:00 UTC 2007
TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection.
Journal of immunology (Baltimore, Md. : 1950)
Yonkers NL,Rodriguez B,Milkovich KA,Asaad R,Lederman MM,Heeger PS,Anthony DD
M700A was used in ELISA to investigate the effect of hepatitis C virus infection on naive CD4 T cell activation
Sun Apr 01 00:00:00 UTC 2007
Granzyme B production distinguishes recently activated CD8(+) memory cells from resting memory cells.
Cellular immunology
Nowacki TM,Kuerten S,Zhang W,Shive CL,Kreher CR,Boehm BO,Lehmann PV,Tary-Lehmann M
M700A was used in ELISA to study the production of granzyme B in newly activated CD8+ memory cells
Tue May 01 00:00:00 UTC 2007
GM-CSF promotes differentiation of human dendritic cells and T lymphocytes toward a predominantly type 1 proinflammatory response.
Experimental hematology
Eksioglu EA,Mahmood SS,Chang M,Reddy V
M700A was used in ELISA to study the role of GM-CSF in promoting differentiation of human dendritic cells and T lymphocytes toward a predominantly type 1 proinflammatory response
Wed Aug 01 00:00:00 UTC 2007
Long term disease-free survival and T cell and antibody responses in women with high-risk Her2+ breast cancer following vaccination against Her2.
Journal of translational medicine
Morse MA,Hobeika A,Osada T,Niedzwiecki D,Marcom PK,Blackwell KL,Anders C,Devi GR,Lyerly HK,Clay TM
M700A was used in ELISA to study the effect of Her2 vaccination in women with high-risk Her2+ breast cancer
Thu Sep 06 00:00:00 UTC 2007
Establishing acceptance criteria for cell-mediated-immunity assays using frozen peripheral blood mononuclear cells stored under optimal and suboptimal conditions.
Clinical and vaccine immunology : CVI
Smith JG,Joseph HR,Green T,Field JA,Wooters M,Kaufhold RM,Antonello J,Caulfield MJ
M700A was used in ELISA to establish acceptance criteria for cell-mediated-immunity assays using frozen PBMCs stored under optimal and suboptimal conditions
Tue May 01 00:00:00 UTC 2007
Mycobacterium tuberculosis growth control by lung macrophages and CD8 cells from patient contacts.
American journal of respiratory and critical care medicine
Carranza C,Juárez E,Torres M,Ellner JJ,Sada E,Schwander SK
M700A was used in ELISA to study Mycobacterium tuberculosis growth control exerted by lung macrophages and CD8 cells from patient contacts
Sun Jan 15 00:00:00 UTC 2006
Epstein-Barr virus (EBV) latent membrane protein-1-specific cytotoxic T lymphocytes targeting EBV-carrying natural killer cell malignancies.
European journal of immunology
Demachi-Okamura A,Ito Y,Akatsuka Y,Tsujimura K,Morishima Y,Takahashi T,Kuzushima K
M700A was used in an ELISpot assay to assess the therapeutic potential of immunotherapy targeting latent membrane protein 1 in Epstein-Barr virus-associated natural killer/T cell malignancies, and chronic active EBV infection.
Wed Mar 01 00:00:00 UTC 2006
Increased frequencies of cochlin-specific T cells in patients with autoimmune sensorineural hearing loss.
Journal of immunology (Baltimore, Md. : 1950)
Baek MJ,Park HM,Johnson JM,Altuntas CZ,Jane-Wit D,Jaini R,Solares CA,Thomas DM,Ball EJ,Robertson NG,Morton CC,Hughes GB,Tuohy VK
M700A was used in ELISA to study the cochlin-specific T cells during autoimmune sensorineural hearing loss
Fri Sep 15 00:00:00 UTC 2006
IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells.
International immunology
Kitawaki T,Kadowaki N,Sugimoto N,Kambe N,Hori T,Miyachi Y,Nakahata T,Uchiyama T
M700A was used in ELISA to investigate the effect of IgE-activated mast cells in combination with pro-inflammatory factors for the induction of Th2-promoting dendritic cells
Fri Dec 01 00:00:00 UTC 2006
Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients.
AIDS (London, England)
Fonseca SG,Coutinho-Silva A,Fonseca LA,Segurado AC,Moraes SL,Rodrigues H,Hammer J,Kallás EG,Sidney J,Sette A,Kalil J,Cunha-Neto E
M700A was used in ELISA to identify promiscuous and potentially protective human CD4 T-cell epitopes in conserved regions within the protein-coding genome of HIV-1 clade B
Tue Nov 28 00:00:00 UTC 2006
Human tumor membrane vesicles modified to express glycolipid-anchored IL-12 by protein transfer induce T cell proliferation in vitro: a potential approach for local delivery of cytokines during vaccination.
Vaccine
Nagarajan S,Selvaraj P
M700A was used in ELISA to study the role of tumor membrane vesicles modified with GPI-anchored cytokines in T cell proliferation
Mon Mar 20 00:00:00 UTC 2006
Safety and immunogenicity of attenuated Salmonella enterica serovar Typhimurium delivering an HIV-1 Gag antigen via the Salmonella Type III secretion system.
Vaccine
Kotton CN,Lankowski AJ,Scott N,Sisul D,Chen LM,Raschke K,Borders G,Boaz M,Spentzou A,Galán JE,Hohmann EL
M700A was used in ELISA to study the safety and immunogenicity of attenuated Salmonella typhimurium delivering a HIV-1 Gag antigen via the Salmonella Type III secretion system
Mon Sep 11 00:00:00 UTC 2006
Immunomodulation in type 1 diabetes by NBI-6024, an altered peptide ligand of the insulin B epitope.
Scandinavian journal of immunology
Alleva DG,Maki RA,Putnam AL,Robinson JM,Kipnes MS,Dandona P,Marks JB,Simmons DL,Greenbaum CJ,Jimenez RG,Conlon PJ,Gottlieb PA
M700A was used in ELISA to investigate the role of a peptide ligand of insulin B epitope in type 1 diabetes
Sun Jan 01 00:00:00 UTC 2006
Stability of interferon-gamma and interleukin-10 responses to Plasmodium falciparum liver stage antigen-1 and thrombospondin-related adhesive protein in residents of a malaria holoendemic area.
The American journal of tropical medicine and hygiene
Moormann AM,John CC,Sumba PO,Tisch D,Embury P,Kazura JW
M700A was used in ELISA to study the cytokine responses to Plasmodium falciparum liver stage antigen-1 and TRAP by Kenyans from a holoendemic area
Sat Apr 01 00:00:00 UTC 2006
Hepatitis C virus-specific reactivity of CD4+-lymphocytes in children born from HCV-infected women.
Journal of hepatology
Della Bella S,Riva A,Tanzi E,Nicola S,Amendola A,Vecchi L,Nebbia G,Longhi R,Zanetti AR,Villa ML
M700A was used in ELISA to investigate the reactivity of CD4+ lymphocytes specific to hepatitis C virus in children born from HCV-infected women
Thu Sep 01 00:00:00 UTC 2005
Cellular immune selection with hepatitis C virus persistence in humans.
The Journal of experimental medicine
Cox AL,Mosbruger T,Mao Q,Liu Z,Wang XH,Yang HC,Sidney J,Sette A,Pardoll D,Thomas DL,Ray SC
M700A was used in ELISA to study whether immunologically driven sequence variation occurs with HCV persistence in humans
Mon Jun 06 00:00:00 UTC 2005
Islet-cell antigen-reactive T cells show different expansion rates and Th1/Th2 differentiation in type 1 diabetic patients and healthy controls.
Clinical immunology (Orlando, Fla.)
Ott PA,Herzog BA,Quast S,Hofstetter HH,Boehm BO,Tary-Lehmann M,Durinovic-Bello I,Berner BR,Lehmann PV
M700A was used in ELISA to study the interferon-gamma production in response to proinsulin, IA-2, and GAD65 peptides in T1D subjects
Fri Apr 01 00:00:00 UTC 2005
Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells.
Clinical immunology (Orlando, Fla.)
Baecher-Allan C,Wolf E,Hafler DA
M700A was used in ELISA to study cytokine production profile of human regulatory CD4+CD25+ T cells
Fri Apr 01 00:00:00 UTC 2005
Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients.
Microbes and infection
Fonseca SG,Moins-Teisserenc H,Clave E,Ianni B,Nunes VL,Mady C,Iwai LK,Sette A,Sidney J,Marin ML,Goldberg AC,Guilherme L,Charron D,Toubert A,Kalil J,Cunha-Neto E
M700A was used in ELISA to identify the CD8+ epitopes in T cells from chronically Trypanosoma cruzi-infected patients
Fri Apr 01 00:00:00 UTC 2005
Resident Th1-like effector memory cells in pulmonary recall responses to Mycobacterium tuberculosis.
American journal of respiratory cell and molecular biology
Walrath J,Zukowski L,Krywiak A,Silver RF
M700A was used in ELISA to investigate the mechanism for the pulmonary memory responses to Mycobacterium tuberculosis
Fri Jul 01 00:00:00 UTC 2005
Aberrant regulation of interleukin-12 receptor beta2 chain on type 1 cytokine-stimulated T lymphocytes in type 1 diabetes.
Immunology
Skarsvik S,Ludvigsson J,Vaarala O
M700A was used in ELISA to study the interferon-gamma secretion of T cells in children
Tue Feb 01 00:00:00 UTC 2005
Memory T-cell response to rotavirus detected with a gamma interferon enzyme-linked immunospot assay.
Journal of virology
Kaufhold RM,Field JA,Caulfield MJ,Wang S,Joseph H,Wooters MA,Green T,Clark HF,Krah D,Smith JG
M700A was used in ELISA to evaluate the cell-mediated immunity responses to rotavirus
Sun May 01 00:00:00 UTC 2005
Tenascin-C, over expressed in lung cancer down regulates effector functions of tumor infiltrating lymphocytes.
Lung cancer (Amsterdam, Netherlands)
Parekh K,Ramachandran S,Cooper J,Bigner D,Patterson A,Mohanakumar T
M700A was used in ELISA to analyze the frequency of tumor infiltrating lymphocytes secreting interferon-gamma
Sat Jan 01 00:00:00 UTC 2005
Redox equilibrium in mucosal T cells tunes the intestinal TCR signaling threshold.
Journal of immunology (Baltimore, Md. : 1950)
Reyes BM,Danese S,Sans M,Fiocchi C,Levine AD
M700A was used in ELISA to investigate the role of redox equilibrium in mucosal T cells
Mon Aug 15 00:00:00 UTC 2005
Human CD4+ effector memory T cells persisting in the microenvironment of lung cancer xenografts are activated by local delivery of IL-12 to proliferate, produce IFN-gamma, and eradicate tumor cells.
Journal of immunology (Baltimore, Md. : 1950)
Broderick L,Yokota SJ,Reineke J,Mathiowitz E,Stewart CC,Barcos M,Kelleher RJ,Bankert RB
M700A was used in ELISA to study the effect of interleukin-12 on the memory T cells persisting in lung cancer xenografts
Sat Jan 15 00:00:00 UTC 2005
CpG RNA: identification of novel single-stranded RNA that stimulates human CD14+CD11c+ monocytes.
Journal of immunology (Baltimore, Md. : 1950)
Sugiyama T,Gursel M,Takeshita F,Coban C,Conover J,Kaisho T,Akira S,Klinman DM,Ishii KJ
M700A was used in ELISA to characterize the effect of novel single-stranded RNA on human CD14+CD11c+ monocytes
Tue Feb 15 00:00:00 UTC 2005
Sequential immune escape and shifting of T cell responses in a long-term survivor of melanoma.
Journal of immunology (Baltimore, Md. : 1950)
Yamshchikov GV,Mullins DW,Chang CC,Ogino T,Thompson L,Presley J,Galavotti H,Aquila W,Deacon D,Ross W,Patterson JW,Engelhard VH,Ferrone S,Slingluff CL
M700A was used in ELISA to characterize the immune response in a long-term survivor of melanoma
Wed Jun 01 00:00:00 UTC 2005
Recipient-specific tolerance after HLA-mismatched umbilical cord blood stem cell transplantation.
Transplantation
Kleen TO,Kadereit S,Fanning LR,Jaroscak J,Fu P,Meyerson HJ,Kulchycki L,Slivka LF,Kozik M,Tary-Lehmann M,Laughlin MJ
M700A was used in ELISA to investigate the mechanisms for the recipient-specific tolerance after stem cell transplantation
Tue Nov 15 00:00:00 UTC 2005
Differential effect of interleukin-2 treatment on primary and secondary immunizations in HIV infected individuals.
AIDS (London, England)
Kuekrek H,Schlingmann T,Valdez H,Boehm BO,Pollard RB,Mitsuyasu R,Goebel FD,Lederman MM,Lehmann PV,Tary-Lehmann M
M700A was used in ELISA to study the usefulness of interleukin 2 treatment in HIV infected individuals
Fri Nov 18 00:00:00 UTC 2005
Retroviral vector backbone immunogenicity: identification of cytotoxic T-cell epitopes in retroviral vector-packaging sequences.
Gene therapy
Kondo E,Akatsuka Y,Nawa A,Kuzushima K,Tsujimura K,Tanimoto M,Kodera Y,Morishima Y,Kuzuya K,Takahashi T
M700A was used in ELISA to study the immunogenicity of retroviral vector backbone in packaging sequences
Tue Feb 01 00:00:00 UTC 2005
Phenotypic and functional analysis of EBV-specific memory CD8 cells in SLE.
Cellular immunology
Berner BR,Tary-Lehmann M,Yonkers NL,Askari AD,Lehmann PV,Anthony DD
M700A was used in ELISA to investigate the phenotype and function of Epstein-Barr virus (EBV)-specific CD8 cells
Sun May 01 00:00:00 UTC 2005
IL-2 absorption affects IFN-gamma and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays.
Cellular immunology
Quast S,Zhang W,Shive C,Kovalovski D,Ott PA,Herzog BA,Boehm BO,Tary-Lehmann M,Karulin AY,Lehmann PV
M700A was used in ELISA to study the role of interleukin-2 absorption in interferon-gamma and interleukin-5 producing memory T cells
Thu Sep 01 00:00:00 UTC 2005
Immunization of volunteers with Salmonella enterica serovar Typhi strain Ty21a elicits the oligoclonal expansion of CD8+ T cells with predominant Vbeta repertoires.
Infection and immunity
Salerno-Gonçalves R,Wahid R,Sztein MB
M700A was used in ELISA to study the effect of Salmonella enterica serovar Typhi strain Ty21a immunization on CD8+ T cells
Wed Jun 01 00:00:00 UTC 2005
HLA-A2 supertype-restricted cell-mediated immunity by peripheral blood mononuclear cells derived from Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy controls.
Infection and immunity
Lyke KE,Burges RB,Cissoko Y,Sangare L,Kone A,Dao M,Diarra I,Fernández-Vina MA,Plowe CV,Doumbo OK,Sztein MB
M700A was used in ELISA to investigate the presence of HLA-A2 supertype-restricted cell-mediated immunity in peripheral blood mononuclear cells derived from Malian children
Thu Sep 01 00:00:00 UTC 2005
Distinct Th1- and Th2-Type prenatal cytokine responses to Plasmodium falciparum erythrocyte invasion ligands.
Infection and immunity
Malhotra I,Mungai P,Muchiri E,Ouma J,Sharma S,Kazura JW,King CL
M700A was used in ELISA to characterize the prenatal immune responses against Plasmodium falciparum erythrocyte invasion ligands
Wed Jun 01 00:00:00 UTC 2005
Human mesenchymal stem cells require monocyte-mediated activation to suppress alloreactive T cells.
Experimental hematology
Groh ME,Maitra B,Szekely E,Koç ON
M700A was used in ELISA to investigate the interaction between blood monocytes and the human bone marrow-derived mesenchymal cells
Mon Aug 01 00:00:00 UTC 2005
A single administration of recombinant human interleukin-12 is associated with increased expression levels of interferon-gamma and signal transducer and activator of transcription in healthy subjects.
Journal of clinical pharmacology
Trudeau C,Cotreau MM,Stonis L,Dykstra KH,Oestreicher JL,Strahs A,Dorner AJ,Van Cleave VH,Trepicchio WL,Schwertschlag US
M700A was used in ELISA to study the role of rhIL-12 in interferon-gamma and signal transducer and activator of transcription
Wed Jun 01 00:00:00 UTC 2005
Donor-specific hyporesponsiveness in ELISPOT assay is associated with early recurrence of hepatitis C in liver transplant recipients.
Human immunology
Tambur AR,Ben-Ari Z,Herrera ND,Klein T,Michowiz R,Mor E
M700A was used in ELISA to investigate the effect of hepatitis C for immune response in liver transplant recipients
Sat Jan 01 00:00:00 UTC 2005
Cytokine and chemokine receptor profile of peripheral blood mononuclear cells during treatment with infliximab in patients with active rheumatoid arthritis.
Annals of the rheumatic diseases
Nissinen R,Leirisalo-Repo M,Peltomaa R,Palosuo T,Vaarala O
M700A was used in ELISA to investigate the effect of infliximab treatment on cytokine and chemokine receptor production in peripheral blood mononuclear cells
Tue Jun 01 00:00:00 UTC 2004
Identification of novel CTL epitopes of CMV-pp65 presented by a variety of HLA alleles.
Blood
Kondo E,Akatsuka Y,Kuzushima K,Tsujimura K,Asakura S,Tajima K,Kagami Y,Kodera Y,Tanimoto M,Morishima Y,Takahashi T
M700A was used in ELISA to identify novel cytotoxic T-lymphocyte epitopes derived from CMV-pp65
Thu Jan 15 00:00:00 UTC 2004
Lactobacillus GG effect in increasing IFN-gamma production in infants with cow's milk allergy.
The Journal of allergy and clinical immunology
Pohjavuori E,Viljanen M,Korpela R,Kuitunen M,Tiittanen M,Vaarala O,Savilahti E
M700A was used in ELISA to study the role of probiotic bacteria in the treatment of cow's milk allergy and IgE-associated dermatitis
Thu Jul 01 00:00:00 UTC 2004
Graft-versus-Tax response in adult T-cell leukemia patients after hematopoietic stem cell transplantation.
Cancer research
Harashima N,Kurihara K,Utsunomiya A,Tanosaki R,Hanabuchi S,Masuda M,Ohashi T,Fukui F,Hasegawa A,Masuda T,Takaue Y,Okamura J,Kannagi M
M700A was used in ELISA to investigate the graft-versus-Tax response in adult T-cell leukemia patients after hematopoietic stem cell transplantation
Thu Jan 01 00:00:00 UTC 2004
T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading.
Journal of clinical immunology
Ott PA,Dittrich MT,Herzog BA,Guerkov R,Gottlieb PA,Putnam AL,Durinovic-Bello I,Boehm BO,Tary-Lehmann M,Lehmann PV
M700A was used in ELISA to investigate the repertoire of T cells in human type 1 diabetes
Thu Jul 01 00:00:00 UTC 2004
Long-term treatment with etanercept significantly reduces the number of proinflammatory cytokine-secreting peripheral blood mononuclear cells in patients with rheumatoid arthritis.
Rheumatology (Oxford, England)
Schotte H,Schlüter B,Willeke P,Mickholz E,Schorat MA,Domschke W,Gaubitz M
M700A was used in ELISA to study the effect of etanercept treatment on proinflammatory cytokine-secreting peripheral blood mononuclear cells in rheumatoid arthritic patients
Sun Aug 01 00:00:00 UTC 2004
Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides.
Journal of virology
Kaufmann DE,Bailey PM,Sidney J,Wagner B,Norris PJ,Johnston MN,Cosimi LA,Addo MM,Lichterfeld M,Altfeld M,Frahm N,Brander C,Sette A,Walker BD,Rosenberg ES
M700A was used in ELISA to determine the breadths and specificities of HIV-1-specific CD4 T-cell responses
Sat May 01 00:00:00 UTC 2004
IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis-pulsed macrophages and impairs the lytic activity of CD4 and CD8 CTL in tuberculosis patients.
Clinical and experimental immunology
de la Barrera S,Aleman M,Musella R,Schierloh P,Pasquinelli V,Garcia V,Abbate E,Sasiain Mdel C
M700A was used in ELISA to study the role of interleukin-10 during Mycobacterium tuberculosis infection in mycobacteria persistence inside host macrophages
Fri Oct 01 00:00:00 UTC 2004
Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950)
Lovett-Racke AE,Hussain RZ,Northrop S,Choy J,Rocchini A,Matthes L,Chavis JA,Diab A,Drew PD,Racke MK
M700A was used in ELISA to study the roles of the peroxisome proliferator-activated receptor alpha in the therapy of autoimmune diseases
Sat May 01 00:00:00 UTC 2004
Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation.
Bone marrow transplantation
Maitra B,Szekely E,Gjini K,Laughlin MJ,Dennis J,Haynesworth SE,Koç ON
M700A was used in ELISA to investigate the immune interaction of human MSCs with the unrelated donor hematopoietic stem cells in vitro
Mon Mar 01 00:00:00 UTC 2004
Impeded Th1 CD4 memory T cell generation in chronic-persisting liver infection with Echinococcus multilocularis.
International immunology
Manfras BJ,Reuter S,Wendland T,Boehm BO,Kern P
M700A was used in ELISA to determine the frequency of circulating CD4+ T cells secreting interferon-gamma
Thu Jan 01 00:00:00 UTC 2004
Active specific immunotherapy of melanoma with a GM3 ganglioside-based vaccine: a report on safety and immunogenicity.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Guthmann MD,Bitton RJ,Carnero AJ,Gabri MR,Cinat G,Koliren L,Lewi D,Fernandez LE,Alonso DF,Gómez DE,Fainboim L
M700A was used in ELISA to investigate the reliability of GM3/VSSP vaccine for melanoma therapy
Mon Apr 18 00:00:00 UTC 2005
Tc1 effector diversity shows dissociated expression of granzyme B and interferon-gamma in HIV infection.
AIDS (London, England)
Kleen TO,Asaad R,Landry SJ,Boehm BO,Tary-Lehmann M
M700A was used in ELISA to investigate the secretion of interferon gamma in cytotoxic effector T cell triggered by various HLA class I-restricted HIV peptides
Fri Feb 20 00:00:00 UTC 2004
Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen.
Scandinavian journal of immunology
Rasmussen AB,Zocca MB,Bonefeld CM,von Essen M,Lauritsen JP,Tomra S,Ødum N,Geisler C
M700A was used in ELISA to investigate the effect of DNA vaccine modification for the improvement of MART-1 induced immune response
Sun Feb 01 00:00:00 UTC 2004
Gamma interferon responses to Plasmodium falciparum liver-stage antigen 1 and thrombospondin-related adhesive protein and their relationship to age, transmission intensity, and protection against malaria.
Infection and immunity
John CC,Moormann AM,Sumba PO,Ofulla AV,Pregibon DC,Kazura JW
M700A was used in ELISA to characterize the gamma interferon responses to Plasmodium falciparum liver-stage antigen 1 and thrombospondin-related adhesive protein
Wed Sep 01 00:00:00 UTC 2004
Generation of three-dimensional pannus-like tissues in vitro from single cell suspensions of synovial fluid cells from arthritis patients.
Rheumatology international
Solomon S,Masilamani M,Mohanty S,Schwab JE,Boneberg EM,Illges H
M700A was used in ELISA to investigate the generation of three-dimensional pannus-like tissues in vitro from single cell suspensions of synovial fluid cells from arthritis patients
Mon Mar 01 00:00:00 UTC 2004
CD28 costimulation enhances the sensitivity of the ELISPOT assay for detection of antigen-specific memory effector CD4 and CD8 cell populations in human diseases.
Journal of immunological methods
Ott PA,Berner BR,Herzog BA,Guerkov R,Yonkers NL,Durinovic-Bello I,Tary-Lehmann M,Lehmann PV,Anthony DD
M700A was used in ELISA to evaluate a novel strategy for detection of CD4 and CD8 cells in human diseases
Sun Feb 15 00:00:00 UTC 2004
Heterophile antibody interference in a multiplexed fluorescent microsphere immunoassay for quantitation of cytokines in human serum.
Clinical and diagnostic laboratory immunology
Martins TB,Pasi BM,Litwin CM,Hill HR
M700A was used in ELISA to study heterophile antibody interference in a multiplexed fluorescent microsphere immunoassay for quantitation of cytokines in human serum
Mon Mar 01 00:00:00 UTC 2004
Deficient IFN-gamma expression in umbilical cord blood (UCB) T cells can be rescued by IFN-gamma-mediated increase in NFATc2 expression.
Journal of clinical immunology
Kadereit S,Junge GR,Kleen T,Kozik MM,Kaminski BA,Daum-Woods K,Fu P,Tary-Lehmann M,Laughlin MJ
M700A was used in ELISA to study the interplay between interferon-gamma expression and NFATc2 expression
Sat Nov 01 00:00:00 UTC 2003
NKG2D engagement of colorectal cancer-specific T cells strengthens TCR-mediated antigen stimulation and elicits TCR independent anti-tumor activity.
European journal of immunology
Maccalli C,Pende D,Castelli C,Mingari MC,Robbins PF,Parmiani G
M700A was used in ELISA to study the role of NKG2D in anti-tumor reactivity by T lymphocytes
Tue Jul 01 00:00:00 UTC 2003
Squamous cell carcinoma cells differentially stimulate NK cell effector functions: the role of IL-18.
Cancer immunology, immunotherapy : CII
Moore MB,Kurago ZB,Fullenkamp CA,Lutz CT
M700A was used in ELISA to investigate the role of interleukin 18 during NK cell activation induced by tumor cells
Sat Feb 01 00:00:00 UTC 2003
Identification of early secretory antigen target-6 epitopes for the immunodiagnosis of active tuberculosis.
Molecular medicine (Cambridge, Mass.)
Vincenti D,Carrara S,De Mori P,Pucillo LP,Petrosillo N,Palmieri F,Armignacco O,Ippolito G,Girardi E,Amicosante M,Goletti D
M700A was used in ELISA to identify the early secretory antigen target-6 epitopes during the the immunodiagnosis of active tuberculosis
Fri Feb 20 00:00:00 UTC 2004
Human CD4+ T cells present within the microenvironment of human lung tumors are mobilized by the local and sustained release of IL-12 to kill tumors in situ by indirect effects of IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950)
Hess SD,Egilmez NK,Bailey N,Anderson TM,Mathiowitz E,Bernstein SH,Bankert RB
M700A was used in ELISA to study the effect of interferon gamma on interleukin 12 release and CD4+ T cell mobilization
Wed Jan 01 00:00:00 UTC 2003
CTLA-4 in filarial infections: implications for a role in diminished T cell reactivity.
Journal of immunology (Baltimore, Md. : 1950)
Steel C,Nutman TB
M700A was used in ELISA to investigate the role of CTLA-4 in mediating the diminished T cell reactivity
Sat Feb 15 00:00:00 UTC 2003
Concomitant induction of CD4+ and CD8+ T cell responses in volunteers immunized with Salmonella enterica serovar typhi strain CVD 908-htrA.
Journal of immunology (Baltimore, Md. : 1950)
Salerno-Gonçalves R,Wyant TL,Pasetti MF,Fernandez-Viña M,Tacket CO,Levine MM,Sztein MB
M700A was used in ELISA to investigate the induction of CD4+ and CD8+ T cell responses in volunteers immunized with Salmonella enterica serovar typhi strain CVD 908-htrA
Sat Mar 01 00:00:00 UTC 2003
Human T-cells recognise N-terminally Fmoc-modified peptide.
Vaccine
Mannering SI,Purcell AW,Honeyman MC,McCluskey J,Harrison LC
M700A was used in ELISA to investigate the effect of N-terminally Fmoc-modified peptide for human CD4+ T-cell induction
Mon Sep 08 00:00:00 UTC 2003
A genome-based functional screening approach to vaccine development that combines in vitro assays and DNA immunization.
Vaccine
Delcayre A,Peake JS,White DJ,Yuan S,McDonald MK,Liang A,Tan PL,Watson JD
M700A was used in ELISA to develop a two-step screening strategy to identify strong immunogenic polypeptides with putative vaccine and/or adjuvant activity.
Fri Jul 04 00:00:00 UTC 2003
Serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women.
International archives of allergy and immunology
Tsunoda M,Litonjua AA,Kuniak MP,Weiss ST,Satoh T,Guevarra L,Tollerud DJ
M700A was used in ELISA to investigate the relationship between serum cytokine levels, cigarette smoking and airway responsiveness among pregnant women
Sat Feb 01 00:00:00 UTC 2003
Influence of maternal filariasis on childhood infection and immunity to Wuchereria bancrofti in Kenya.
Infection and immunity
Malhotra I,Ouma JH,Wamachi A,Kioko J,Mungai P,Njzovu M,Kazura JW,King CL
M700A was used in ELISA to investigate the role of maternal filariasis in childhood infection
Mon Sep 01 00:00:00 UTC 2003
CD4+ and CD8+ cells in cryopreserved human PBMC maintain full functionality in cytokine ELISPOT assays.
Journal of immunological methods
Kreher CR,Dittrich MT,Guerkov R,Boehm BO,Tary-Lehmann M
M700A was used in ELISA to investigate the function of CD4+ and CD8+ cells in cryopreserved human peripheral blood mononuclear cells
Tue Jul 01 00:00:00 UTC 2003
Detection of low-frequency antigen-specific IL-10-producing CD4(+) T cells via ELISPOT in PBMC: cognate vs. nonspecific production of the cytokine.
Journal of immunological methods
Guerkov RE,Targoni OS,Kreher CR,Boehm BO,Herrera MT,Tary-Lehmann M,Lehmann PV,Schwander SK
M700A was used in ELISA to investigate the expression of low-frequency antigen-specific interleukin-10-producing CD4+ T cells in peripheral blood mononuclear cells
Fri Aug 01 00:00:00 UTC 2003
Monitoring indirect presentation of alloantigens by utilizing the autologous processing machinery of dendritic cells in-vitro.
Journal of immunological methods
Tambur AR
M700A was used in ELISA to evaluate a novel approach for monitoring alloantigen presentation
Mon Dec 01 00:00:00 UTC 2003
Monocyte chemoattractant protein-1 levels in bronchoalveolar lavage fluid of lung-transplanted patients treated with tacrolimus as rescue treatment for refractory acute rejection.
Transplantation proceedings
Meloni F,Cascina A,Paschetto E,Marone Bianco A,Morosini M,Pellegrini C,Fietta A,Vitulo P,Pozzi E,Viganò M
M700A was used in ELISA to investigate the effect of immunosuppressive regimens on cytokine expression in lung transplanted patients
Sun Jun 01 00:00:00 UTC 2003
Human CD4+ effector T cells mediate indirect interleukin-12- and interferon-gamma-dependent suppression of autologous HLA-negative lung tumor xenografts in severe combined immunodeficient mice.
Cancer research
Egilmez NK,Hess SD,Chen FA,Takita H,Conway TF,Bankert RB
M700A was used in ELISA to investigate the role of CD4+ effector T cells in autologous HLA-negative lung tumor xenografts in severe combined immunodeficient mice
Wed May 01 00:00:00 UTC 2002
Glycolipid-anchored IL-12 expressed on tumor cell surface induces antitumor immune response.
Cancer research
Nagarajan S,Selvaraj P
M700A was used in ELISA to investigate the effect of GPI-interleukin 12 for tumor inhibition in vivo
Wed May 15 00:00:00 UTC 2002
Differing influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections.
The Journal of infectious diseases
Libraty DH,Endy TP,Houng HS,Green S,Kalayanarooj S,Suntayakorn S,Chansiriwongs W,Vaughn DW,Nisalak A,Ennis FA,Rothman AL
M700A was used in ELISA to investigate the influences of virus burden and immune activation on disease severity in secondary dengue-3 virus infections
Wed May 01 00:00:00 UTC 2002
Identification of HLA-A3-restricted CD8+ T cell epitopes derived from mammaglobin-A, a tumor-associated antigen of human breast cancer.
International journal of cancer
Jaramillo A,Majumder K,Manna PP,Fleming TP,Doherty G,Dipersio JF,Mohanakumar T
M700A was used in ELISA to identify the HLA-A3-restricted mammaglobin-A-derived epitopes
Tue Dec 10 00:00:00 UTC 2002
A HLA-A2 restricted human CTL line recognizes a novel tumor cell expressed p53 epitope.
International journal of cancer
Würtzen PA,Claesson MH
M700A was used in ELISA to characterize a HLA-A2 restricted p53-specifc human CTL line
Sat Jun 01 00:00:00 UTC 2002
Age-dependent cellular immune responses to Plasmodium vivax Duffy binding protein in humans.
Journal of immunology (Baltimore, Md. : 1950)
Xainli J,Baisor M,Kastens W,Bockarie M,Adams JH,King CL
M700A was used in ELISA to investigate the role of plasmodium vivax duffy binding protein
Sun Sep 15 00:00:00 UTC 2002
Acquired immune responses to Plasmodium falciparum merozoite surface protein-1 in the human fetus.
Journal of immunology (Baltimore, Md. : 1950)
King CL,Malhotra I,Wamachi A,Kioko J,Mungai P,Wahab SA,Koech D,Zimmerman P,Ouma J,Kazura JW
M700A was used in ELISA to demonstrate the fetal immune response to plasmodium falciparum merozoite surface protein-1
Tue Jan 01 00:00:00 UTC 2002
Inhibition of human CD4(+)CD25(+high) regulatory T cell function.
Journal of immunology (Baltimore, Md. : 1950)
Baecher-Allan C,Viglietta V,Hafler DA
M700A was used in ELISA to study the regulatory mechanisms of autoreactive T cells
Sun Dec 01 00:00:00 UTC 2002
Characterization of CD8(+) effector T cell responses in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine.
Journal of immunology (Baltimore, Md. : 1950)
Salerno-Goncalves R,Pasetti MF,Sztein MB
M700A was used in ELISA to investigate the frequency of CD8+ effector T cell responses in volunteers immunized with Salmonella enterica serovar Typhi strain Ty21a typhoid vaccine
Thu Aug 15 00:00:00 UTC 2002
Vaccination of patients with metastatic renal cell carcinoma with autologous dendritic cells pulsed with autologous tumor antigens in combination with interleukin-2: a phase 1 study.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Oosterwijk-Wakka JC,Tiemessen DM,Bleumer I,de Vries IJ,Jongmans W,Adema GJ,Debruyne FM,de Mulder PH,Oosterwijk E,Mulders PF
M700A was used in ELISA to perform a phase 1 study in metastatic renal cell carcinoma using autologous immature dendritic cells loaded with autologous tumorlysate as a vaccine
Fri Apr 25 00:00:00 UTC 2003
Oligoclonal analysis of the atopic T cell response to the group 1 allergen of Cynodon dactylon (bermuda grass) pollen: pre- and post-allergen-specific immunotherapy.
International archives of allergy and immunology
Eusebius NP,Papalia L,Suphioglu C,McLellan SC,Varney M,Rolland JM,O'Hehir RE
M700A was used in ELISA to study the atopic T cell response to the group 1 allergen of Cynodon dactylon (bermuda grass) pollen
Fri Mar 01 00:00:00 UTC 2002
Modulation of an interleukin-12 and gamma interferon synergistic feedback regulatory cycle of T-cell and monocyte cocultures by Porphyromonas gingivalis lipopolysaccharide in the absence or presence of cysteine proteinases.
Infection and immunity
Yun PL,DeCarlo AA,Collyer C,Hunter N
M700A was used in ELISA to study the modulation of an IL-12 and gamma interferon regulatory cycle in T cell/monocyte co-cultures by Porphyromonas gingivalis lipopolysaccharide
Tue Oct 01 00:00:00 UTC 2002
Safety and shedding of an attenuated strain of Listeria monocytogenes with a deletion of actA/plcB in adult volunteers: a dose escalation study of oral inoculation.
Infection and immunity
Angelakopoulos H,Loock K,Sisul DM,Jensen ER,Miller JF,Hohmann EL
M700A was used in ELISA to study the safety and shedding of an attenuated strain of Listeria monocytogenes with a deletion of actA/plcB
Mon Jul 01 00:00:00 UTC 2002
Enhanced interleukin-12 and CD40 ligand activities but reduced Staphylococcus aureus Cowan 1-induced responses suggest a generalized and progressively impaired type 1 cytokine pattern for human schistosomiasis.
Infection and immunity
Montenegro SM,Abath FG,Domingues AL,Melo WG,Morais CN,Coutinho EM,Mahanty S,Wynn TA
M700A was used in ELISA to study the role of type 1 cytokine in chronic hepatosplenic schistosomiasis
Fri Nov 01 00:00:00 UTC 2002
Interferon-gamma production to inner ear antigens by T cells from patients with autoimmune sensorineural hearing loss.
Journal of neuroimmunology
Lorenz RR,Solares CA,Williams P,Sikora J,Pelfrey CM,Hughes GB,Tuohy VK
M700A was used in ELISA to study the production of IFN-gamma in response to inner ear antigens by T cells from patients with autoimmune sensorineural hearing loss
Sun Sep 01 00:00:00 UTC 2002
Sex differences in cytokine responses to myelin peptides in multiple sclerosis.
Journal of neuroimmunology
Pelfrey CM,Cotleur AC,Lee JC,Rudick RA
M700A was used in ELISA to investigate the mechanism for the sex-dependent myelin peptide cytokine responses in multiple sclerosis
Sun Sep 01 00:00:00 UTC 2002
Interferon-beta increases the stimulatory capacity of monocyte-derived dendritic cells to induce IL-13, IL-5 and IL-10 in autologous T-cells.
Journal of neuroimmunology
Wiesemann E,Sönmez D,Heidenreich F,Windhagen A
M700A was used in ELISA to investigate the effect of interferon beta on the function of monocyte-derived dendritic cells
Fri Feb 01 00:00:00 UTC 2002
Measurement of interferon-gamma by high-throughput fluorometric microvolume assay technology system.
Journal of immunological methods
Komatsu N,Shichijo S,Maeda Y,Itoh K
M700A was used in ELISA to develop a high-throughput fluorometric microvolume assay technology for measurement of interferon-gamma
Wed May 01 00:00:00 UTC 2002
Rapid and efficient generation of lentivirally gene-modified dendritic cells from DC progenitors with bone marrow stromal cells.
Journal of immunological methods
Sumimoto H,Tsuji T,Miyoshi H,Hagihara M,Takada-Yamazaki R,Okamoto S,Ikeda Y,Takahashi T,Kawakami Y
M700A was used in ELISA to develop a rapid and efficient method for generating lentivirally gene-modified dendritic cells from dendritic cell progenitors
Fri Dec 20 00:00:00 UTC 2002
Adaptive immune responses of patients with asthma to the attachment (G) glycoprotein of respiratory synctial virus.
The Journal of infectious diseases
Hancock GE,Scheuer CA,Sierzega R,Pryharski KS,McBride JT,Watelet LF,Tebbey PW,Smith JD
M700A was used in ELISA to study the effect of the attachment (G) glycoprotein from respiratory synctial virus on wheezing
Sat Dec 15 00:00:00 UTC 2001
Schistosoma haematobium-induced urinary tract morbidity correlates with increased tumor necrosis factor-alpha and diminished interleukin-10 production.
The Journal of infectious diseases
King CL,Malhotra I,Mungai P,Wamachi A,Kioko J,Muchiri E,Ouma JH
M700A was used in ELISA to investigate the role of schistosoma haematobium-induced urinary tract morbidity
Thu Nov 01 00:00:00 UTC 2001
Inhibition of human immunodeficiency virus type 1 gp120 presentation to CD4 T cells by antibodies specific for the CD4 binding domain of gp120.
Journal of virology
Hioe CE,Tuen M,Chien PC,Jones G,Ratto-Kim S,Norris PJ,Moretto WJ,Nixon DF,Gorny MK,Zolla-Pazner S
M700A was used in ELISA to examine the number of T cells producing gamma interferon in response to gp120
Thu Nov 01 00:00:00 UTC 2001
Molecular mimicry in Lyme arthritis demonstrated at the single cell level: LFA-1 alpha L is a partial agonist for outer surface protein A-reactive T cells.
Journal of immunology (Baltimore, Md. : 1950)
Trollmo C,Meyer AL,Steere AC,Hafler DA,Huber BT
M700A was used in ELISA to study the role of OspA and LFA-1alpha(L) in Lyme arthritis at the T cell level
Sun Apr 15 00:00:00 UTC 2001
A T cell clone's avidity is a function of its activation state.
Journal of immunology (Baltimore, Md. : 1950)
Hesse MD,Karulin AY,Boehm BO,Lehmann PV,Tary-Lehmann M
M700A was used in ELISA to investigate the role of T cell activation state in its functional avidity
Wed Aug 01 00:00:00 UTC 2001
Functional and structural similarity of V gamma 9V delta 2 T cells in humans and Aotus monkeys, a primate infection model for Plasmodium falciparum malaria.
Journal of immunology (Baltimore, Md. : 1950)
Daubenberger CA,Salomon M,Vecino W,Hübner B,Troll H,Rodriques R,Patarroyo ME,Pluschke G
M700A was used in ELISA to investigate of the conversative nature of V gamma 9V delta 2 T cells between humans and Aotus monkeys
Sat Dec 01 00:00:00 UTC 2001
Transmission intensity determines lymphocyte responsiveness and cytokine bias in human lymphatic filariasis.
Journal of immunology (Baltimore, Md. : 1950)
King CL,Connelly M,Alpers MP,Bockarie M,Kazura JW
M700A was used in ELISA to investigate the effect of the intensity of exposure to L3 on lymphocyte responsiveness and cytokine bias in human lymphatic filariasis
Fri Jun 15 00:00:00 UTC 2001
Hydrolysis of interleukin-12 by Porphyromonas gingivalis major cysteine proteinases may affect local gamma interferon accumulation and the Th1 or Th2 T-cell phenotype in periodontitis.
Infection and immunity
Yun PL,Decarlo AA,Collyer C,Hunter N
M700A was used in ELISA to study the role of the Porphyromonas gingivalis gingipains in IL-12 cleavage and the effect on IFN-gamma accumulation and Th1/Th2 T-cell phenotype in periodontitis
Sat Sep 01 00:00:00 UTC 2001
Glatiramer acetate (GA) induces IL-13/IL-5 secretion in naive T cells.
Journal of neuroimmunology
Wiesemann E,Klatt J,Sönmez D,Blasczyk R,Heidenreich F,Windhagen A
M700A was used in ELISA to study the role of glatiramer acetate in interleukin 13/interleukin 5 secretion in naive T cells
Mon Sep 03 00:00:00 UTC 2001
Multiplexed fluorescent bead-based immunoassays for quantitation of human cytokines in serum and culture supernatants.
Cytometry
Kellar KL,Kalwar RR,Dubois KA,Crouse D,Chafin WD,Kane BE
M700A was used in ELISA to develop multiplexed fluorescent bead-based immunoassays for quantitation of human cytokines in serum and culture supernatants
Sat Sep 01 00:00:00 UTC 2001
Development and validation of a gamma interferon ELISPOT assay for quantitation of cellular immune responses to varicella-zoster virus.
Clinical and diagnostic laboratory immunology
Smith JG,Liu X,Kaufhold RM,Clair J,Caulfield MJ
M700A was used in ELISA to investigate the efficiency of a gamma interferon ELISPOT assay for quantitation of cellular immune responses to varicella-zoster virus
Sat Sep 01 00:00:00 UTC 2001
CD40-ligand (CD154) gene therapy for chronic lymphocytic leukemia.
Blood
Wierda WG,Cantwell MJ,Woods SJ,Rassenti LZ,Prussak CE,Kipps TJ
M700A was used in ELISA to evaluate the CD154 gene therapy for chronic lymphocytic leukemia
Wed Nov 01 00:00:00 UTC 2000
Analysis of successful immune responses in persons infected with hepatitis C virus.
The Journal of experimental medicine
Lechner F,Wong DK,Dunbar PR,Chapman R,Chung RT,Dohrenwend P,Robbins G,Phillips R,Klenerman P,Walker BD
M700A was used in ELISA to study the T lymphocyte response during and after acute resolving HCV infection
Mon May 01 00:00:00 UTC 2000
IL-10 secretion and sensitivity in normal human intestine and inflammatory bowel disease.
Journal of clinical immunology
Gasche C,Bakos S,Dejaco C,Tillinger W,Zakeri S,Reinisch W
M700A was used in ELISA to investigate the secretion and sensitivity of interleukin 10 in normal human intestine and inflammatory bowel disease
Fri Sep 01 00:00:00 UTC 2000
Human infection with Ascaris lumbricoides is associated with a polarized cytokine response.
The Journal of infectious diseases
Cooper PJ,Chico ME,Sandoval C,Espinel I,Guevara A,Kennedy MW,Urban JF,Griffin GE,Nutman TB
M700A was used in ELISA to investigate the induction of a polarized cytokine response during human infection with Ascaris lumbricoides
Sun Oct 01 00:00:00 UTC 2000
Direct visualization of cytokine-producing recall antigen-specific CD4 memory T cells in healthy individuals and HIV patients.
Journal of immunology (Baltimore, Md. : 1950)
Helms T,Boehm BO,Asaad RJ,Trezza RP,Lehmann PV,Tary-Lehmann M
M700A was used in ELISA to study the cytokine production by recall Ag-specific CD4 memory T cells.
Sat Apr 01 00:00:00 UTC 2000
Quantification of self-recognition in multiple sclerosis by single-cell analysis of cytokine production.
Journal of immunology (Baltimore, Md. : 1950)
Pelfrey CM,Rudick RA,Cotleur AC,Lee JC,Tary-Lehmann M,Lehmann PV
M700A was used in ELISA to investigate the autoaggressive responses in multiple sclerosis
Tue Aug 01 00:00:00 UTC 2000
A randomized prospective trial of low-dose OKT3 induction therapy to prevent rejection and minimize side effects in recipients of kidney transplants.
Transplantation
Flechner SM,Goldfarb DA,Fairchild R,Modlin CS,Fisher R,Mastroianni B,Boparai N,O'Malley KJ,Cook DJ,Novick AC
M700A was used in ELISA to perform a randomized prospective trial of low-dose OKT3 induction therapy to prevent rejection and minimize side effects in recipients of kidney transplants
Thu Jun 15 00:00:00 UTC 2000
Circulating T-cell response to Helicobacter pylori infection in chronic gastritis.
Helicobacter
Ren Z,Pang G,Lee R,Batey R,Dunkley M,Borody T,Clancy R
M700A was used in ELISA to study the circulating T-cell response to Helicobacter pylori infection in chronic gastritis
Fri Sep 01 00:00:00 UTC 2000
Cytokines delivered by biodegradable microspheres promote effective suppression of human tumors by human peripheral blood lymphocytes in the SCID-Winn model.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Egilmez NK,Jong YS,Hess SD,Jacob JS,Mathiowitz E,Bankert RB
M700A was used in ELISA to study the role of cytokines in suppression of human tumors
Thu Jun 15 00:00:00 UTC 2000
Immune responses to hepatitis C and non-hepatitis C antigens in hepatitis C virus infected and HIV-1 coinfected patients.
AIDS (London, England)
Valdez H,Anthony D,Farukhi F,Patki A,Salkowitz J,Heeger P,Peterson DL,Post AB,Asaad R,Lederman MM
M700A was used in ELISA to investigate the immune responses to hepatitis C and non-hepatitis C antigens
Fri Oct 20 00:00:00 UTC 2000
Interleukin-12 delivered by biodegradable microspheres promotes the antitumor activity of human peripheral blood lymphocytes in a human head and neck tumor xenograft/SCID mouse model.
Head & neck
Kuriakose MA,Chen FA,Egilmez NK,Jong YS,Mathiowitz E,DeLacure MD,Hicks WL,Loree TL,Bankert RB
M700A was used in ELISA to study the effect of exogenous interleukin 12 on the tumor progression
Sat Jan 01 00:00:00 UTC 2000
Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes.
Proceedings of the National Academy of Sciences of the United States of America
She JX,Ellis TM,Wilson SB,Wasserfall CH,Marron M,Reimsneider S,Kent SC,Hafler DA,Neuberg DS,Muir A,Strominger JL,Atkinson MA
M700A was used in ELISA to study the possible roles of the heterophile antibodies in type 1 diabetes
Tue Jul 06 00:00:00 UTC 1999
Cytokine production in acute versus chronic human Schistosomiasis mansoni: the cross-regulatory role of interferon-gamma and interleukin-10 in the responses of peripheral blood mononuclear cells and splenocytes to parasite antigens.
The Journal of infectious diseases
Montenegro SM,Miranda P,Mahanty S,Abath FG,Teixeira KM,Coutinho EM,Brinkman J,Gonçalves I,Domingues LA,Domingues AL,Sher A,Wynn TA
M700A was used in ELISA to investigate the role of interferon-gamma and interleukin-10 in human Schistosomiasis mansoni responses
Tue Jun 01 00:00:00 UTC 1999
T-cell anergy induced by clonotype-specific antibodies: modulation of an autoreactive human T-cell clone in vitro.
Immunology
Steenbakkers PG,Boots AM,Rijnders AW
M700A was used in ELISA to investigate the anergy in autoreactive human T cells triggered by clonotype-specific antibodies
Thu Apr 01 00:00:00 UTC 1999
IL-18 promotes type 1 cytokine production from NK cells and T cells in human intracellular infection.
Journal of immunology (Baltimore, Md. : 1950)
García VE,Uyemura K,Sieling PA,Ochoa MT,Morita CT,Okamura H,Kurimoto M,Rea TH,Modlin RL
M700A was used in ELISA to investigate the role of interleukin-18 for type 1 cytokine production from natural killer cells and T cells in human intracellular infection
Sat May 15 00:00:00 UTC 1999
Helminth- and Bacillus Calmette-Guérin-induced immunity in children sensitized in utero to filariasis and schistosomiasis.
Journal of immunology (Baltimore, Md. : 1950)
Malhotra I,Mungai P,Wamachi A,Kioko J,Ouma JH,Kazura JW,King CL
M700A was used in ELISA to investigate the prenatal immunity against helminth infection
Tue Jun 01 00:00:00 UTC 1999
Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes.
Journal of immunology (Baltimore, Md. : 1950)
Heeger PS,Greenspan NS,Kuhlenschmidt S,Dejelo C,Hricik DE,Schulak JA,Tary-Lehmann M
M700A was used in ELISA to study the effect of donor memory lymphocytes in transplant rejection and survival
Sun Aug 15 00:00:00 UTC 1999
Activation of human CD8+ alpha beta TCR+ cells by Mycobacterium tuberculosis via an alternate class I MHC antigen-processing pathway.
Journal of immunology (Baltimore, Md. : 1950)
Canaday DH,Ziebold C,Noss EH,Chervenak KA,Harding CV,Boom WH
M700A was used in ELISA to characterize the activation of human CD8+ alpha beta TCR+ cells in response to Mycobacterium tuberculosis
Fri Jan 01 00:00:00 UTC 1999
Increased interleukin-4 and interleukin-5 production in response to Schistosoma haematobium adult worm antigens correlates with lack of reinfection after treatment.
The Journal of infectious diseases
Medhat A,Shehata M,Bucci K,Mohamed S,Dief AD,Badary S,Galal H,Nafeh M,King CL
M700A was used in ELISA to investigate the roles of interleukin 4 and 5 in the immune response against Schistosoma haematobium
Sat Aug 01 00:00:00 UTC 1998
Down-regulation of CD1 on antigen-presenting cells by infection with Mycobacterium tuberculosis.
Journal of immunology (Baltimore, Md. : 1950)
Stenger S,Niazi KR,Modlin RL
M700A was used in ELISA to study the effect of Mycobacterium tuberculosis infection on CD1 expression
Thu Oct 01 00:00:00 UTC 1998
Bacille Calmette-Guérin vaccination enhances human gamma delta T cell responsiveness to mycobacteria suggestive of a memory-like phenotype.
Journal of immunology (Baltimore, Md. : 1950)
Hoft DF,Brown RM,Roodman ST
M700A was used in ELISA to investigate the effect of Bacille Calmette-Guerin vaccination on gamma delta T cell activity
Wed Jul 15 00:00:00 UTC 1998
NK cell natural cytotoxicity and IFN-gamma production are not always coordinately regulated: engagement of DX9 KIR+ NK cells by HLA-B7 variants and target cells.
Journal of immunology (Baltimore, Md. : 1950)
Kurago ZB,Lutz CT,Smith KD,Colonna M
M700A was used in ELISA to study the mechanism for the cytotoxicity of natural killer cells
Sun Feb 15 00:00:00 UTC 1998
Antitumor immune response of human peripheral blood lymphocytes coengrafted with tumor into severe combined immunodeficient mice.
Cancer research
Iwanuma Y,Chen FA,Egilmez NK,Takita H,Bankert RB
M700A was used in ELISA to investigate the antitumor activity of human peripheral blood lymphocytes coengrafted with tumor into SCID mice
Tue Jul 15 00:00:00 UTC 1997
Systemic bias of cytokine production toward cell-mediated immune regulation in IDDM and toward humoral immunity in Graves' disease.
Diabetes
Kallmann BA,Hüther M,Tubes M,Feldkamp J,Bertrams J,Gries FA,Lampeter EF,Kolb H
M700A was used in ELISA to investigate the change of immune regulation in IDDM and Graves disease
Sat Feb 01 00:00:00 UTC 1997
Streptococcal preparation OK-432 is a potent inducer of IL-12 and a T helper cell 1 dominant state.
Journal of immunology (Baltimore, Md. : 1950)
Fujimoto T,Duda RB,Szilvasi A,Chen X,Mai M,O'Donnell MA
M700A was used in ELISA to study the effect of streptococcal preparation OK-432 on interleukin 12 expression and Thl-dominant state
Sun Jun 15 00:00:00 UTC 1997
The IgV domain of human B7-2 (CD86) is sufficient to co-stimulate T lymphocytes and induce cytokine secretion.
International immunology
Rennert P,Furlong K,Jellis C,Greenfield E,Freeman GJ,Ueda Y,Levine B,June CH,Gray GS
M700A was used in ELISA to investigate the role of the IgV domain of human B7-2 in T lymphocyte stimulation and cytokine secretion
Sun Jun 01 00:00:00 UTC 1997
A sensitive ELISPOT assay to detect low-frequency human T lymphocytes.
Journal of immunological methods
McCutcheon M,Wehner N,Wensky A,Kushner M,Doan S,Hsiao L,Calabresi P,Ha T,Tran TV,Tate KM,Winkelhake J,Spack EG
M700A was used in ELISA to modify a sensitive ELISPOT assay to detect low-frequency human T lymphocytes
Mon Dec 29 00:00:00 UTC 1997
IL-12 synthesis by human Langerhans cells.
Journal of immunology (Baltimore, Md. : 1950)
Kang K,Kubin M,Cooper KD,Lessin SR,Trinchieri G,Rook AH
M700A was used in ELISA to investigate the synthesis of interleukin 12 in human Langerhans cells
Thu Feb 15 00:00:00 UTC 1996
Detection and quantification of blood-derived CD8+ T lymphocytes secreting tumor necrosis factor alpha in response to HLA-A2.1-binding melanoma and viral peptide antigens.
Journal of immunological methods
Herr W,Schneider J,Lohse AW,Meyer zum Büschenfelde KH,Wölfel T
M700A was used in ELISA to study the role of tumor necross factor alpha in response to HLA-A2.1-binding melanoma and viral peptide antigens
Mon May 27 00:00:00 UTC 1996
Definition of a lamina propria T cell responsive state. Enhanced cytokine responsiveness of T cells stimulated through the CD2 pathway.
Journal of immunology (Baltimore, Md. : 1950)
Targan SR,Deem RL,Liu M,Wang S,Nel A
M700A was used in ELISA to investigate the changes of cytokine production in T cells induced by antibodies
Sun Jan 15 00:00:00 UTC 1995
Influence of CD28 co-stimulation on cytokine production is mainly regulated via interleukin-2.
Immunology
Kuiper HM,de Jong R,Brouwer M,Lammers K,Wijdenes J,van Lier RA
M700A was used in ELISA to investigate the role of interleukin 2 for CD28 co-stimulation on cytokine production
Thu Sep 01 00:00:00 UTC 1994
