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Invitrogen
IFNLR1 Polyclonal Antibody
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IFNLR1 Antibody (PA5-47713) in WB
Western blot analysis of IFNLR1 in human heart tissue. Samples were incubated in IFNLR1 polyclonal antibody (Product # PA5-47713) using a dilution of 2 µg/mL followed by a HRP-conjugated Anti-Sheep IgG secondary antibody. A specific band was detected for IL‚28 Rα/IFN‚λ R1 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions.
Product Details
PA5-47713
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL-28 R alpha/IFN-lambda R1 Arg21-Ala228
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2606887
Product Specific Information
In direct ELISAs, less than 5% cross-reactivity with recombinant mouse IL-28 R alpha is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: class II cytokine receptor CRF2/12; CRF2-12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN-lambda receptor 1; IFN-lambda-R1; IL-28 receptor subunit alpha; IL-28R-alpha; IL-28RA; Interferon lambda receptor 1; interferon lambda, receptor 1; interferon, lambda receptor 1; interleukin 28 alpha receptor; interleukin 28 receptor A; interleukin 28 receptor, alpha (interferon, lambda receptor); interleukin or cytokine receptor 2; Interleukin-28; Interleukin-28 receptor subunit alpha; LICR2; Likely interleukin or cytokine receptor 2
Gene Aliases: CRF2/12; IFNLR; IFNLR1; IL-28R1; IL28RA; LICR2
UniProt ID: (Human) Q8IU57
Entrez Gene ID: (Human) 163702
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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