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Invitrogen
IFRD1 Polyclonal Antibody
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Product Details
PA5-54985
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human IFRD1. Recombinant protein control fragment (Product #RP-92274).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642645
Product Specific Information
Immunogen sequence: AKVDKRKQRS VFRDVLRAVE ERDFPTETIK FGPERMYIDC WVKKHTYDTF KEVLGSGMQY HLQSNEFLRN VFELGPPVML DAATLK
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 95%.
Target Information
Tis7, also known as IFRD1, is a 442 amino acid containing membrane associated, non-nuclear intracellular protein belonging to the IFRD family. A regulatory protein expressed in a variety of tissues, Tis7 is known to play an important role in the regulation of gene activity in the proliferative and/or differentiative pathways induced by NGF. Reports suggest that Tis7 may be an autocrine factor that attenuates or amplifies the initial ligand induced signal and might also augment the adaptive response by stimulating the production of differentiated enterocytes. Tis7 acts as a negative regulator of transcriptional activity and represses expression of genes involved in myogenesis, muscle maintenance, and regeneration in a histone deacetylase dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 12-O-tetradecanoylphorbol-13-acetate-induced sequence 7; Interferon-related developmental regulator 1; Nerve growth factor-inducible protein PC4; pheochromocytoma cell-4; TPA induced sequence 7
Gene Aliases: IFRD1; PC4; TIS7
UniProt ID: (Human) O00458
Entrez Gene ID: (Human) 3475
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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