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Invitrogen
IFT172 Polyclonal Antibody
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Product Details
PA5-25305
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 28-57 amino acids from the N-terminal region of human IFT172
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542805
Product Specific Information
This antibody is predicted to react with rat based on sequence homology.
Target Information
IFT172 is required for the maintenance and formation of cilia. IT plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: intraflagellar transport 172 homolog; intraflagellar transport 172 protein; Intraflagellar transport protein 172 homolog; Protein wimple; selective LIM binding factor homolog; selective LIM-binding factor Wimple; wimple homolog
Gene Aliases: 4930553F24Rik; avc1; BBS20; IFT172; KIAA1179; NPHP17; osm-1; RP71; SLB; SRTD10; Wim
UniProt ID: (Human) Q9UG01, (Mouse) Q6VH22
Entrez Gene ID: (Human) 26160, (Mouse) 67661
negative regulation of transcription from RNA polymerase II promoter
neural tube formation
neural tube closure
heart looping
Notch signaling pathway
smoothened signaling pathway
multicellular organism development
determination of left/right symmetry
brain development
heart development
epidermis development
regulation of smoothened signaling pathway
dorsal/ventral pattern formation
protein processing
spinal cord motor neuron differentiation
neural tube development
cytoplasmic microtubule organization
cilium assembly
positive regulation of smoothened signaling pathway
negative regulation of epithelial cell proliferation
palate development
limb development
cilium morphogenesis
bone development
hindgut development
left/right axis specification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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