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Invitrogen
IFT172 Polyclonal Antibody
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Product Details
PA5-60861
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human IFT172. Recombinant protein control fragment (Product #RP-91636).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642648
Product Specific Information
Immunogen sequence: SSPGTNCAEA YHSWADLRDV LFNLCENLVK SSEANSPAHE EFKTMLLIAH YYATRSAAQS VKQLETVAAR LSVSLLRHTQ LLPVDKAFYE AGIAAKAVGW DNMAFIFLNR
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
Target Information
IFT172 is required for the maintenance and formation of cilia. IT plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: intraflagellar transport 172 homolog; Intraflagellar transport protein 172 homolog; selective LIM binding factor homolog; wimple homolog
Gene Aliases: BBS20; IFT172; KIAA1179; NPHP17; osm-1; RP71; SLB; SRTD10; wim
UniProt ID: (Human) Q9UG01
Entrez Gene ID: (Human) 26160
neural tube closure
heart looping
Notch signaling pathway
smoothened signaling pathway
brain development
epidermis development
dorsal/ventral pattern formation
protein processing
spinal cord motor neuron differentiation
cytoplasmic microtubule organization
cilium assembly
positive regulation of smoothened signaling pathway
negative regulation of epithelial cell proliferation
palate development
limb development
bone development
hindgut development
left/right axis specification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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