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Invitrogen
IFT88 Polyclonal Antibody
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IFT88 Antibody (PA5-99962) in IHC (P)
Immunohistochemistry analysis of IFT88 in mouse muscle tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with IFT88 polyclonal antibody (Product # PA5-99962) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-99962
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IFT88, corresponding to a region within C-terminal amino acids.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818895
Product Specific Information
Antibody detects endogenous levels of total IFT88.
Target Information
This gene encodes a member of the tetratrico peptide repeat family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:20606; intraflagellar transport 88 homolog; Intraflagellar transport protein 88 homolog; MGC26259; polaris homolog; probe hTg737 (polycystic kidney disease, autosomal recessive); Recessive polycystic kidney disease protein Tg737; Recessive polycystic kidney disease protein Tg737 homolog; RP11-172H24.2; testicular tissue protein Li 93; tetratricopeptide repeat domain 10; Tetratricopeptide repeat protein 10; Tg737 protein; TgN(Imorpk)737Rpw; TPR repeat protein 10; transgene insert site 737, insertional mutation, polycystic kidney disease
Gene Aliases: AW552028; D13S1056E; DAF19; flexo; fxo; hTg737; IFT88; orpk; polaris; TG737; Tg737Rpw; TgN737Rpw; TTC10
UniProt ID: (Human) Q13099, (Mouse) Q61371
Entrez Gene ID: (Human) 8100, (Dog) 477345, (Mouse) 21821, (Rat) 305918
cilium morphogenesis
regulation of cilium assembly
regulation of autophagosome assembly
eye development
kidney development
liver development
epithelial cell morphogenesis
Notch signaling pathway
smoothened signaling pathway
sperm axoneme assembly
spermatid nucleus elongation
determination of left/right symmetry
nervous system development
brain development
heart development
protein localization
epidermis development
regulation of smoothened signaling pathway
organ morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
spinal cord dorsal/ventral patterning
telencephalon development
cell projection organization
lung development
pancreas development
cytoplasmic microtubule organization
response to fluid shear stress
nonmotile primary cilium assembly
epidermal stem cell homeostasis
cilium assembly
regulation of odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of insulin-like growth factor receptor signaling pathway
regulation of fat cell differentiation
forebrain morphogenesis
negative regulation of epithelial cell proliferation
cardiac muscle cell differentiation
palate development
inner ear receptor stereocilium organization
limb development
regulation of feeding behavior
cardiac septum morphogenesis
lung vasculature development
heart formation
neural precursor cell proliferation
regulation of protein processing
cochlea development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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