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Invitrogen
IFT88 Recombinant Rabbit Monoclonal Antibody (23GB4015)
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FIGURE: 1 / 4
IFT88 Antibody (MA5-53670) in ICC/IF
Immunocytochemistry analysis of IFT88 in HeLa cells. Nuclei were stained blue with DAPI; IFT88 recombinant monoclonal antibody (Product # MA5-53670) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Product Details
MA5-53670
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
23GB4015
Immunogen
A synthesized peptide derived from IFT88 (1-28AA).
Conjugate
Form
Liquid
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3248141
Target Information
This gene encodes a member of the tetratrico peptide repeat family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:20606; intraflagellar transport 88 homolog; Intraflagellar transport protein 88 homolog; MGC26259; polaris homolog; probe hTg737 (polycystic kidney disease, autosomal recessive); Recessive polycystic kidney disease protein Tg737; Recessive polycystic kidney disease protein Tg737 homolog; RP11-172H24.2; testicular tissue protein Li 93; tetratricopeptide repeat domain 10; Tetratricopeptide repeat protein 10; Tg737 protein; TgN(Imorpk)737Rpw; TPR repeat protein 10; transgene insert site 737, insertional mutation, polycystic kidney disease
Gene Aliases: AW552028; D13S1056E; DAF19; flexo; fxo; hTg737; IFT88; orpk; polaris; TG737; Tg737Rpw; TgN737Rpw; TTC10
UniProt ID: (Human) Q13099, (Mouse) Q61371
Entrez Gene ID: (Human) 8100, (Mouse) 21821, (Rat) 305918
cilium morphogenesis
regulation of cilium assembly
regulation of autophagosome assembly
eye development
kidney development
liver development
epithelial cell morphogenesis
Notch signaling pathway
smoothened signaling pathway
sperm axoneme assembly
spermatid nucleus elongation
determination of left/right symmetry
nervous system development
brain development
heart development
protein localization
epidermis development
regulation of smoothened signaling pathway
organ morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
spinal cord dorsal/ventral patterning
telencephalon development
cell projection organization
lung development
pancreas development
cytoplasmic microtubule organization
response to fluid shear stress
nonmotile primary cilium assembly
epidermal stem cell homeostasis
cilium assembly
regulation of odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of insulin-like growth factor receptor signaling pathway
regulation of fat cell differentiation
forebrain morphogenesis
negative regulation of epithelial cell proliferation
cardiac muscle cell differentiation
palate development
inner ear receptor stereocilium organization
limb development
regulation of feeding behavior
cardiac septum morphogenesis
lung vasculature development
heart formation
neural precursor cell proliferation
regulation of protein processing
cochlea development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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