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Product Details
BS-0298R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Sheep,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human IGBP1, amino acids 151-250.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha 4; Alpha4 phosphoprotein; B cell signal transduction molecule alpha 4; B-cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); CD79a-binding protein 1; immunoglobulin (CD79A) binding protein 1; immunoglobulin binding protein 1; Immunoglobulin-binding protein 1; Lymphocyte signal transduction molecule alpha 4; p52; phosphoprotein, component, 52 kDa; Protein alpha-4; Protein phosphatase 2/4/6 regulatory subunit; protein phosphatase 2A, regulatory subunit alpha-4; Renal carcinoma antigen NY-REN-16
Gene Aliases: AI115586; AI662457; ALPHA-4; AW208785; C81413; IBP1; IGBP1; p52; Pc52; Tap42
UniProt ID: (Human) P78318, (Rat) O08836, (Mouse) Q61249
Entrez Gene ID: (Human) 3476, (Sheep) 101121748, (Rat) 58845, (Mouse) 18518
negative regulation of transcription from RNA polymerase II promoter
signal transduction
negative regulation of stress-activated MAPK cascade
regulation of protein phosphatase type 2A activity
response to tumor necrosis factor
positive regulation of dephosphorylation
negative regulation of protein dephosphorylation
B cell activation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of transcription from RNA polymerase II promoter
regulation of microtubule-based movement
response to interleukin-1
negative regulation of apoptotic signaling pathway
regulation of signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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