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Product Details
H00003476-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2B8
Immunogen
IGBP1 (NP_001542, 64 a.a. approximately 165 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RNEDLEEIAS TDLKYLLVPA FQGALTMKQV NPSKRLDHLQ RAREHFINYL TQCHCYHVAE FELPKTMNNS AENHTANSSM AYPSLVAMAS QRQAKIQRYK QK
Target Information
The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B cell signal transduction molecule alpha 4; B-cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); CD79a-binding protein 1; Immunoglobulin-binding protein 1; Protein alpha-4; Protein phosphatase 2/4/6 regulatory subunit; protein phosphatase 2A, regulatory subunit alpha-4; Renal carcinoma antigen NY-REN-16
Gene Aliases: ALPHA-4; IBP1; IGBP1
UniProt ID: (Human) P78318
Entrez Gene ID: (Human) 3476
negative regulation of transcription from RNA polymerase II promoter
signal transduction
negative regulation of stress-activated MAPK cascade
regulation of protein phosphatase type 2A activity
response to tumor necrosis factor
positive regulation of dephosphorylation
negative regulation of protein dephosphorylation
B cell activation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of transcription from RNA polymerase II promoter
regulation of microtubule-based movement
response to interleukin-1
negative regulation of apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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