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Abnova
IGHA2 Polyclonal Antibody, MaxPab™
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Product Details
H00003494-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IGHA2 (AAH73765.1, 1 a.a. approximately 477 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKHLWFFLLL VAAPRWVLSQ VQLQESGPGL VKPSETLSLT CTVSGGSISS YYWSWIRQTA GKGLEWIGYI SHSGSTTYNP SLKSRVTLSL DTSKNQFSLR LNSVTAADTA VYYCAHGSSW DFAFDYWGQG TLVTVSSASP TSPKVFPLSL DSTPQDGNVV VACLVQGFFP QEPLSVTWSE SGQNVTARNF PPSQDASGDL YTTSSQLTLP ATQCPDGKSV TCHVKHYTNP SQDVTVPCPV PPPPPCCHPR LSLHRPALED LLLGSEANLT CTLTGLRDAS GATFTWTPSS GKSAVQGPPE RDLCGCYSVS SVLPGCAQPW NHGETFTCTA AHPELKTPLT ANITKSGNTF RPEVHLLPPP SEELALNELV TLTCLARGFS PKDVLVRWLQ GSQELPREKY LTWASRQEPS QGTTTFAVTS ILRVAAEDWK KGDTFSCMVG HEALPLAFTQ KTIDRLAGKP THVNVSVVMA EVDGTCY
Target Information
The Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system. The human alpha 1 and two allelic alpha 2 immunoglobulin heavy chain constant region genes contain three exons, each encoding a single constant region protein domain. Alignment of the alpha 1 and alpha 2 gene sequences reveals an unusual coupled deletion-duplication in the 5'-flanking region, which can be explained in terms of a slipped-strand mispairing model. Comparison of nucleotide sequences of the alpha 1 gene and two alleles of the alpha 2 gene indicates a localized transfer of genetic information from the 3' end of the alpha 1 gene to one of the alpha 2 alleles, probably by a gene conversion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ig alpha-2 chain C region; Ig alpha-2 chain C region BUT; Ig alpha-2 chain C region LAN; IGHA2Immunoglobulin heavy constant alpha 2
Entrez Gene ID: (Human) 3494
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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