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Proteintech
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Immunogen sequence: YLDDIVPEN YSHENSQGSS HAATKPQGPA ASTRTGSQRQ EGGQEAAAPA RQGRKKPAGK SLASEAPSQP SLNGGSPEGV ESQDGVDHFR AMIVEFMASK KMQLEFPPSL NSHDRLRVHQ IAEEHGLRHD SSGEGKRRFI TVSKRAPRPR AALGPPAGTG GPAPLQPVPP TPAQTEQPPR EQRGPDQPDL RTLHLERLQR VRSAQGQPAS KEQQASGQQK LPEKKKKKAK GHPATDLPTE EDFEALVSAA VKADNTCGFA KCTAGVTTLG QFCQLCSRRY CLSHHLPEIH GCGERARAHA RQRISREGVL YAGSGTKNGS LDPAKRAQLQ RRLDKKLSEL SNQRTSRRKE RGT (642-993 aa encoded by BC105088)
5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent helicase IGHMBP2; cardiac transcription factor 1; DNA-binding protein SMUBP-2; GF-1; Glial factor 1; Immunoglobulin mu-binding protein 2; zinc finger, AN1-type domain 7
Gene Aliases: CATF1; CMT2S; HCSA; HMN6; IGHMBP2; SMARD1; SMBP2; SMUBP2; ZFAND7
UniProt ID: (Human) P38935
Entrez Gene ID: (Human) 3508
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