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FIGURE: 1 / 1
Sequence of this protein is as follows: EQRGPDQPDL RTLHLERLQR VRSAQGQPAS KEQQASGQQK LPEKKKKKAK GHPATDLPTE EDFEALVSAA VKADNTCGFA
5' to 3' helicase that unwinds RNA and DNA duplices in an ATP-dependent reaction. Acts as a transcription regulator. Required for the transcriptional activation of the flounder liver-type antifreeze protein gene. Exhibits strong binding specificity to the enhancer element B of the flounder antifreeze protein gene intron. Binds to the insulin II gene RIPE3B enhancer region. May be involved in translation. DNA-binding protein specific to 5'-phosphorylated single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. Preferentially binds to the 5'-GGGCT-3' motif. Interacts with tRNA-Tyr. Stimulates the transcription of the human neurotropic virus JCV.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP-dependent helicase IGHMBP2; cardiac transcription factor 1; DNA-binding protein SMUBP-2; GF-1; Glial factor 1; Immunoglobulin mu-binding protein 2; zinc finger, AN1-type domain 7
Gene Aliases: CATF1; CMT2S; HCSA; HMN6; IGHMBP2; SMARD1; SMBP2; SMUBP2; ZFAND7
UniProt ID: (Human) P38935
Entrez Gene ID: (Human) 3508
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