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          • Primary Antibodies ›
          • J Chain Antibodies

          OriGene

          IGJ Monoclonal Antibody (OTI3E12), TrueMAB™

          View all (31) J Chain antibodies

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          Cite IGJ Monoclonal Antibody (OTI3E12), TrueMAB™

          • Antibody Testing Data (2)
          IGJ Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          IGJ Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          IGJ Antibody (TA504172) in WB

          HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IGJ (RC207932, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-IGJ. Positive lysates LY403400 (100 µg) and LC403400 (20 µg) can be purchased separately from OriGene. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          IGJ Antibody in Western Blot (WB)
          IGJ Antibody in Flow Cytometry (Flow)

          Product Details

          TA504172

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000
          -

          Flow Cytometry (Flow)

          1:100
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          OTI3E12

          Immunogen

          Full length human recombinant protein of human IGJ produced in HEK293T cell.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.53 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS with 1% BSA, 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: IgJ chain; Immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; J chain; Joining chain of multimeric IgA and IgM

          View more View less

          Gene Aliases: IGCJ; IGJ; JCH; JCHAIN

          View more View less

          UniProt ID: (Human) P01591

          View more View less

          Entrez Gene ID: (Human) 3512

          View more View less

          Function(s)
          single-stranded DNA binding antigen binding IgA binding phosphatidylcholine binding immunoglobulin receptor binding protein homodimerization activity peptidoglycan binding
          Process(es)
          retina homeostasis adaptive immune response glomerular filtration receptor-mediated endocytosis immune response antibacterial humoral response positive regulation of protein oligomerization innate immune response positive regulation of respiratory burst
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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