Product References
Monitoring Group 2 Innate Lymphoid Cell Biology in Models of Lung Inflammation.
Bio-protocol
Badrani JH,Strohm AN,Haung YA,Doherty TA
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Thu Jul 20 00:00:00 UTC 2023
Self-amplifying mRNA seasonal influenza vaccines elicit mouse neutralizing antibody and cell-mediated immunity and protect ferrets.
NPJ vaccines
Cheung M,Chang C,Rathnasinghe R,Rossignol E,Zhang Y,Ferrari A,Patel H,Huang Y,Sanchez Guillen M,Scalzo T,Lee C,Otten GR,Settembre EC,Music N,Palladino G,Wen Y
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Wed Oct 04 00:00:00 UTC 2023
Calcaratarin D, a labdane diterpenoid, attenuates mouse asthma via modulating alveolar macrophage function.
British journal of pharmacology
Liao W,Foo HYC,Tran TNQ,Chai CLL,Wong WSF
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2023
Fibroblastic reticular cells in lymph node potentiate white adipose tissue beiging through neuro-immune crosstalk in male mice.
Nature communications
Cheong LY,Wang B,Wang Q,Jin L,Kwok KHM,Wu X,Shu L,Lin H,Chung SK,Cheng KKY,Hoo RLC,Xu A
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Fri Mar 03 00:00:00 UTC 2023
Type 1 Cytotoxic T Cells Increase in Placenta after Intrauterine Inflammation.
Frontiers in immunology
Liu J,Liu Y,Panda S,Liu A,Lei J,Burd I
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Fri Dec 17 00:00:00 UTC 2021
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Cell reports
Teng F,Tachó-Piñot R,Sung B,Farber DL,Worgall S,Hammad H,Lambrecht BN,Hepworth MR,Sonnenberg GF
14-7133-81 was used in Flow cytometry/Cell sorting to demonstrate a critical role for antigen-presenting ILC3s in orchestrating immune tolerance in the airway by restricting pro-inflammatory T cell responses to both allergens and microbes.
Tue Nov 23 00:00:00 UTC 2021
Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism.
Nature communications
Fu Z,Dean JW,Xiong L,Dougherty MW,Oliff KN,Chen ZE,Jobin C,Garrett TJ,Zhou L
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Thu Jul 22 00:00:00 UTC 2021
Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling.
Frontiers in immunology
Deng F,Hu JJ,Yang X,Sun QS,Lin ZB,Zhao BC,Yao ZW,Luo SD,Chen ZL,Liu Y,Yan ZZ,Li C,Liu WF,Liu KX
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Dec 21 00:00:00 UTC 2021
Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling.
Frontiers in immunology
Deng F,Hu JJ,Yang X,Sun QS,Lin ZB,Zhao BC,Yao ZW,Luo SD,Chen ZL,Liu Y,Yan ZZ,Li C,Liu WF,Liu KX
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Dec 21 00:00:00 UTC 2021
Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza.
iScience
Shibuya M,Tamiya S,Kawai A,Hirai T,Cragg MS,Yoshioka Y
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in ELISA
Fri Oct 22 00:00:00 UTC 2021
Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza.
iScience
Shibuya M,Tamiya S,Kawai A,Hirai T,Cragg MS,Yoshioka Y
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in ELISA
Fri Oct 22 00:00:00 UTC 2021
6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function.
eLife
Daneshmandi S,Cassel T,Higashi RM,Fan TW,Seth P
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Thu Oct 28 00:00:00 UTC 2021
Preclinical development of a molecular clamp-stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2.
Clinical & translational immunology
Watterson D,Wijesundara DK,Modhiran N,Mordant FL,Li Z,Avumegah MS,McMillan CL,Lackenby J,Guilfoyle K,van Amerongen G,Stittelaar K,Cheung ST,Bibby S,Daleris M,Hoger K,Gillard M,Radunz E,Jones ML,Hughes K,Hughes B,Goh J,Edwards D,Scoble J,Pearce L,Kowalczyk L,Phan T,La M,Lu L,Pham T,Zhou Q,Brockman DA,Morgan SJ,Lau C,Tran MH,Tapley P,Villalón-Letelier F,Barnes J,Young A,Jaberolansar N,Scott CA,Isaacs A,Amarilla AA,Khromykh AA,van den Brand JM,Reading PC,Ranasinghe C,Subbarao K,Munro TP,Young PR,Chappell KJ
14-7133-81 was used in Flow Cytometry to describe rational antigen design through to manufacturability and vaccine efficacy of a prefusion-stabilised spike protein (Sclamp) in combination with the licensed adjuvant MF59 'MF59C.1' (Seqirus, Parkville, Australia).
Fri Apr 22 00:00:00 UTC 2022
A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.
Nature immunology
Harb H,Stephen-Victor E,Crestani E,Benamar M,Massoud A,Cui Y,Charbonnier LM,Arbag S,Baris S,Cunnigham A,Leyva-Castillo JM,Geha RS,Mousavi AJ,Guennewig B,Schmitz-Abe K,Sioutas C,Phipatanakul W,Chatila TA
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Sun Nov 01 00:00:00 UTC 2020
A helminth-derived suppressor of ST2 blocks allergic responses.
eLife
Vacca F,Chauché C,Jamwal A,Hinchy EC,Heieis G,Webster H,Ogunkanbi A,Sekne Z,Gregory WF,Wear M,Perona-Wright G,Higgins MK,Nys JA,Cohen ES,McSorley HJ
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Mon May 18 00:00:00 UTC 2020
Arf1-mediated lipid metabolism sustains cancer cells and its ablation induces anti-tumor immune responses in mice.
Nature communications
Wang G,Xu J,Zhao J,Yin W,Liu D,Chen W,Hou SX
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Fri Jan 10 00:00:00 UTC 2020
T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation.
Cell reports
Yan J,Pandey SP,Barnes BJ,Turner JR,Abraham C
14-7133 was used in an ELISA assay to identify a previously undefined key role for T cell-intrinsic IRF5. In mice, IRF5 in CD4+ T cells promotes Th1- and Th17-associated cytokines and decreases Th2-associated cytokines.
Tue Jun 30 00:00:00 UTC 2020
Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.
Nature communications
Galle-Treger L,Sankaranarayanan I,Hurrell BP,Howard E,Lo R,Maazi H,Lewis G,Banie H,Epstein AL,Hu P,Rehan VK,Gilliland FD,Allayee H,Soroosh P,Sharpe AH,Akbari O
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Feb 12 00:00:00 UTC 2019
TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity.
Cell reports
Hurrell BP,Galle-Treger L,Jahani PS,Howard E,Helou DG,Banie H,Soroosh P,Akbari O
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Dec 24 00:00:00 UTC 2019
IL-27 targets Foxp3+ Tregs to mediate antiinflammatory functions during experimental allergic airway inflammation.
JCI insight
Nguyen QT,Jang E,Le HT,Kim S,Kim D,Dvorina N,Aronica MA,Baldwin WM,Asosingh K,Comhair S,Min B
14-7133 was used in Flow cytometry/Cell sorting to discover that Tregs during allergic airway inflammation are the primary target cells of IL-27 in order to mediate antinflammatory functions.
Thu Jan 24 00:00:00 UTC 2019
Chronic Liver Disease in Humans Causes Expansion and Differentiation of Liver Lymphatic Endothelial Cells.
Frontiers in immunology
Tamburini BAJ,Finlon JM,Gillen AE,Kriss MS,Riemondy KA,Fu R,Schuyler RP,Hesselberth JR,Rosen HR,Burchill MA
14-7133 was used in Flow cytometry/Cell sorting to demonstrate that chronic liver disease increases the abundance of lymphatic vessels, a trait correlated with areas of fibrosis and immune cell infiltration.
Wed Sep 09 00:00:00 UTC 2020
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.
Immunity
Hirota K,Hashimoto M,Ito Y,Matsuura M,Ito H,Tanaka M,Watanabe H,Kondoh G,Tanaka A,Yasuda K,Kopf M,Potocnik AJ,Stockinger B,Sakaguchi N,Sakaguchi S
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Jun 19 00:00:00 UTC 2018
E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor.
Immunity
Li Q,Li D,Zhang X,Wan Q,Zhang W,Zheng M,Zou L,Elly C,Lee JH,Liu YC
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Feb 20 00:00:00 UTC 2018
The E3 ligase VHL controls alveolar macrophage function via metabolic-epigenetic regulation.
The Journal of experimental medicine
Zhang W,Li Q,Li D,Li J,Aki D,Liu YC
14-7133 was used in Flow cytometry/Cell sorting to show VHL regulates alveolar macrophages and acts as a crucial egulatory factor in lung inflammation and fibrosis.
Mon Dec 03 00:00:00 UTC 2018
Peripheral PDGFRα+gp38+ mesenchymal cells support the differentiation of fetal liver-derived ILC2.
The Journal of experimental medicine
Koga S,Hozumi K,Hirano KI,Yazawa M,Terooatea T,Minoda A,Nagasawa T,Koyasu S,Moro K
14-7133-81 was used in Flow Cytometry to suggest that early differentiation of ILC2 occurs in the fetal liver via IL-7 and Notch signaling, whereas final differentiation occurs in the periphery with the aid of PDGFRα+gp38+ cells.
Mon Jun 04 00:00:00 UTC 2018
Allergen-specific IgG antibody signaling through FcγRIIb promotes food tolerance.
The Journal of allergy and clinical immunology
Burton OT,Tamayo JM,Stranks AJ,Koleoglou KJ,Oettgen HC
14-7133 was used in an ELISA assay to suggest that allergen-specific IgG antibodies can act to induce and sustain immunologic tolerance to foods.
Mon Jan 01 00:00:00 UTC 2018
Glucagon-like peptide 1 receptor signaling attenuates respiratory syncytial virus-induced type 2 responses and immunopathology.
The Journal of allergy and clinical immunology
Bloodworth MH,Rusznak M,Pfister CC,Zhang J,Bastarache L,Calvillo SA,Chappell JD,Boyd KL,Toki S,Newcomb DC,Stier MT,Zhou W,Goleniewska K,Moore ML,Hartert TV,Niswender KD,Peebles RS
14-7133 was used in Flow cytometry/Cell sorting to investigate the effect of activating the GLP-1R signalling pathway on mice mimicking severe respiratory infection.
Wed Aug 01 00:00:00 UTC 2018
Fli1-haploinsufficient dermal fibroblasts promote skin-localized transdifferentiation of Th2-like regulatory T cells.
Arthritis research & therapy
Saigusa R,Asano Y,Taniguchi T,Hirabayashi M,Nakamura K,Miura S,Yamashita T,Takahashi T,Ichimura Y,Toyama T,Yoshizaki A,Trojanowska M,Sato S
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Wed Feb 07 00:00:00 UTC 2018
IgE promotes type 2 innate lymphoid cells in murine food allergy.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
Burton OT,Medina Tamayo J,Stranks AJ,Miller S,Koleoglou KJ,Weinberg EO,Oettgen HC
14-7133 was used in an ELISA assay to determine the effect of IgE mediated mast cell activation on intestinal ILC3 responses following ingestion of food allergens.
Thu Mar 01 00:00:00 UTC 2018
Nematode-Infected Mice Acquire Resistance to Subsequent Infection With Unrelated Nematode by Inducing Highly Responsive Group 2 Innate Lymphoid Cells in the Lung.
Frontiers in immunology
Yasuda K,Adachi T,Koida A,Nakanishi K
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Mon Sep 30 00:00:00 UTC 2019
Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation.
Genome medicine
Pramanik J,Chen X,Kar G,Henriksson J,Gomes T,Park JE,Natarajan K,Meyer KB,Miao Z,McKenzie ANJ,Mahata B,Teichmann SA
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Wed Oct 24 00:00:00 UTC 2018
T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells.
Nature communications
Jain A,Song R,Wakeland EK,Pasare C
14-7133 was used in Flow cytometry/Cell sorting to study the role of IL-1 as a licensing signal for memory CD4 T cell function.
Thu Aug 09 00:00:00 UTC 2018
Epidermal Growth Factor Receptor Expression Licenses Type-2 Helper T Cells to Function in a T Cell Receptor-Independent Fashion.
Immunity
Minutti CM,Drube S,Blair N,Schwartz C,McCrae JC,McKenzie AN,Kamradt T,Mokry M,Coffer PJ,Sibilia M,Sijts AJ,Fallon PG,Maizels RM,Zaiss DM
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Oct 17 00:00:00 UTC 2017
HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.
Immunity
Osbourn M,Soares DC,Vacca F,Cohen ES,Scott IC,Gregory WF,Smyth DJ,Toivakka M,Kemter AM,le Bihan T,Wear M,Hoving D,Filbey KJ,Hewitson JP,Henderson H,Gonzàlez-Cìscar A,Errington C,Vermeren S,Astier AL,Wallace WA,Schwarze J,Ivens AC,Maizels RM,McSorley HJ
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Oct 17 00:00:00 UTC 2017
PD-1 regulates KLRG1+ group 2 innate lymphoid cells.
The Journal of experimental medicine
Taylor S,Huang Y,Mallett G,Stathopoulou C,Felizardo TC,Sun MA,Martin EL,Zhu N,Woodward EL,Elias MS,Scott J,Reynolds NJ,Paul WE,Fowler DH,Amarnath S
14-7133-81 was used in Flow Cytometry to report that PD-1 is required for maintaining the number, and hence function, of KLRG1+ Group 2 innate lymphoid cells.
Mon Jun 05 00:00:00 UTC 2017
IFN-γ Blocks Development of an Asthma Phenotype in Rhinovirus-Infected Baby Mice by Inhibiting Type 2 Innate Lymphoid Cells.
American journal of respiratory cell and molecular biology
Han M,Hong JY,Jaipalli S,Rajput C,Lei J,Hinde JL,Chen Q,Hershenson NM,Bentley JK,Hershenson MB
14-7133 was used in Flow cytometry/Cell sorting to examine the effects of intranasal interferon-γ administration on rhinovirus-induced type 2 innate lymphoid cells expansion and IL-13 expression in 6-day-old BALB/c and IL-13 reporter mice.
Wed Feb 01 00:00:00 UTC 2017
Early IL-6 signalling promotes IL-27 dependent maturation of regulatory T cells in the lungs and resolution of viral immunopathology.
PLoS pathogens
Pyle CJ,Uwadiae FI,Swieboda DP,Harker JA
14-7133-81 was used in Flow Cytometry to show that during respiratory virus infection the prototypic inflammatory cytokine IL-6 is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27.
Fri Sep 01 00:00:00 UTC 2017
IL-17 Receptor A Maintains and Protects the Skin Barrier To Prevent Allergic Skin Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Floudas A,Saunders SP,Moran T,Schwartz C,Hams E,Fitzgerald DC,Johnston JA,Ogg GS,McKenzie AN,Walsh PT,Fallon PG
14-7133-81 was used in Flow Cytometry to describes a protective role for IL-17RA signalling in regulation of the skin barrier and maintenance of skin immune homeostasis.
Sat Jul 15 00:00:00 UTC 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Tue Oct 17 00:00:00 UTC 2017
An asthma-associated IL4R variant exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells.
Nature medicine
Massoud AH,Charbonnier LM,Lopez D,Pellegrini M,Phipatanakul W,Chatila TA
14-7133 was used in Flow cytometry/Cell sorting to identify a previously unknown mechanism for the development of TH17 cell inflammation in genetically prone individuals.
Thu Sep 01 00:00:00 UTC 2016
Acidic chitinase primes the protective immune response to gastrointestinal nematodes.
Nature immunology
Vannella KM,Ramalingam TR,Hart KM,de Queiroz Prado R,Sciurba J,Barron L,Borthwick LA,Smith AD,Mentink-Kane M,White S,Thompson RW,Cheever AW,Bock K,Moore I,Fitz LJ,Urban JF,Wynn TA
14-7133-81 was used in Flow Cytometry to use AMCase-deficient mice as a means to dissect the role of the enzyme in several models of helminth infection and type 2 cytokine–driven airway inflammation.
Sun May 01 00:00:00 UTC 2016
G9a regulates group 2 innate lymphoid cell development by repressing the group 3 innate lymphoid cell program.
The Journal of experimental medicine
Antignano F,Braam M,Hughes MR,Chenery AL,Burrows K,Gold MJ,Oudhoff MJ,Rattray D,Halim TY,Cait A,Takei F,Rossi FM,McNagny KM,Zaph C
14-7133-81 was used in Flow Cytometry to provide the first identification of an epigenetic regulatory mechanism in ILC development and function.
Mon Jun 27 00:00:00 UTC 2016
Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis.
Mucosal immunology
Borthwick LA,Barron L,Hart KM,Vannella KM,Thompson RW,Oland S,Cheever A,Sciurba J,Ramalingam TR,Fisher AJ,Wynn TA
14-7133 was used in Flow cytometry/Cell sorting to show that macrophages are required for the maintenance of type 2 immunity within affected tissues but not within secondary lymphoid organs.
Fri Jan 01 00:00:00 UTC 2016
Secondary allergic T cell responses are regulated by dendritic cell-derived thrombospondin-1 in the setting of allergic eye disease.
Journal of leukocyte biology
Smith RE,Reyes NJ,Khandelwal P,Schlereth SL,Lee HS,Masli S,Saban DR
14713381 was used in flow cytometry to report the contribution of dendritic cell-derived thrombospondin-1 on allergic eye disease
Mon Aug 01 00:00:00 UTC 2016
Monocyte-Derived Dendritic Cells Promote Th Polarization, whereas Conventional Dendritic Cells Promote Th Proliferation.
Journal of immunology (Baltimore, Md. : 1950)
Chow KV,Lew AM,Sutherland RM,Zhan Y
14-7133 was used in Flow cytometry/Cell sorting to investigate how division of labor between moDCs and cDCs has implications for their respective roles in the immune response.
Fri Jan 15 00:00:00 UTC 2016
Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity.
Journal of immunology (Baltimore, Md. : 1950)
Contreras F,Prado C,González H,Franz D,Osorio-Barrios F,Osorio F,Ugalde V,Lopez E,Elgueta D,Figueroa A,Lladser A,Pacheco R
14713381 was used in flow cytometry to investigate how dopamine receptor D3 signaling affects the balance of effector T cells
Sun May 15 00:00:00 UTC 2016
Transcription Factors Oct-1 and GATA-3 Cooperatively Regulate Th2 Cytokine Gene Expression via the RHS5 within the Th2 Locus Control Region.
PloS one
Kim K,Kim N,Lee GR
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Thu Jul 07 00:00:00 UTC 2016
Intratracheal myriocin enhances allergen-induced Th2 inflammation and airway hyper-responsiveness.
Immunity, inflammation and disease
Edukulla R,Rehn KL,Liu B,McAlees JW,Hershey GK,Wang YH,Lewkowich I,Lindsley AW
14-7133 was used in an ELISA assay to evaluate the immune regulatory role of de novo ceramide generation in vitro and in vivo.
Thu Sep 01 00:00:00 UTC 2016
Food allergy in mice is modulated through the thymic stromal lymphopoietin pathway.
Clinical and translational allergy
Frossard CP,Zimmerli SC,Rincon Garriz JM,Eigenmann PA
14-7133 was used in an ELISpot assay to explore the role of thymic stromal lymphopoietin in a mouse model with oral sensitisation and oral challenge eliciting food allergy.
Thu Jan 21 00:00:00 UTC 2016
Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures.
The Journal of allergy and clinical immunology
Gold MJ,Antignano F,Halim TY,Hirota JA,Blanchet MR,Zaph C,Takei F,McNagny KM
14-7133 was used in an ELISA assay to reveal a critical role for ILC2s in the development of adaptive type 2 responses to local antigen exposure.
Tue Apr 01 00:00:00 UTC 2014
Group 2 innate lymphoid cells facilitate sensitization to local, but not systemic, TH2-inducing allergen exposures.
The Journal of allergy and clinical immunology
Gold MJ,Antignano F,Halim TY,Hirota JA,Blanchet MR,Zaph C,Takei F,McNagny KM
14-7133 was used in an ELISA assay to reveal a critical role for ILC2s in the development of adaptive type 2 responses to local antigen exposure.
Tue Apr 01 00:00:00 UTC 2014
Transcriptomics identified a critical role for Th2 cell-intrinsic miR-155 in mediating allergy and antihelminth immunity.
Proceedings of the National Academy of Sciences of the United States of America
Okoye IS,Czieso S,Ktistaki E,Roderick K,Coomes SM,Pelly VS,Kannan Y,Perez-Lloret J,Zhao JL,Baltimore D,Langhorne J,Wilson MS
14-7133-81 was used in Flow cytometry/Cell sorting to identify the microRNA and mRNA transcriptome of highly purified cytokine-expressing Th1, Th2, Th9, Th17, and Treg cells from allergy, infection, and autoimmune disease models.
Tue Jul 29 00:00:00 UTC 2014
Few Foxp3⁺ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity.
European journal of immunology
Mayer CT,Ghorbani P,Kühl AA,Stüve P,Hegemann M,Berod L,Gershwin ME,Sparwasser T
14-7133-81 was used in Flow Cytometry to study the mechanisms underlying why regulatory T cell-depletion fails to cause autoimmunity in adult Depletion of REGulatory T cells mice.
Wed Oct 01 00:00:00 UTC 2014
Innate and adaptive type 2 immune cell responses in genetically controlled resistance to intestinal helminth infection.
Immunology and cell biology
Filbey KJ,Grainger JR,Smith KA,Boon L,van Rooijen N,Harcus Y,Jenkins S,Hewitson JP,Maizels RM
14-7133 was used in Flow cytometry/Cell sorting to study the differential levels of resistance to the nematode, H. polygyrus, that are observable between mouse models.
Wed Jan 07 00:00:00 UTC 2015
Type 2 innate lymphoid cells control eosinophil homeostasis.
Nature
Nussbaum JC,Van Dyken SJ,von Moltke J,Cheng LE,Mohapatra A,Molofsky AB,Thornton EE,Krummel MF,Chawla A,Liang HE,Locksley RM
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Flow Cytometry
Thu Oct 10 00:00:00 UTC 2013
The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.
The Journal of clinical investigation
Katsumoto TR,Kudo M,Chen C,Sundaram A,Callahan EC,Zhu JW,Lin J,Rosen CE,Manz BN,Lee JW,Matthay MA,Huang X,Sheppard D,Weiss A
14-7133 was used in Flow cytometry/Cell sorting to investigate the signalling pathways that promote increased airway smooth muscle contractility and airway hyperresponsiveness in asthma.
Wed May 01 00:00:00 UTC 2013
IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1.
The Journal of experimental medicine
Jenkins SJ,Ruckerl D,Thomas GD,Hewitson JP,Duncan S,Brombacher F,Maizels RM,Hume DA,Allen JE
14-7133 was used in Functional assays to study the dependence of tissue-resident macrophage proliferation which avoids coincident monocyte recruitment on IL-4 production.
Mon Oct 21 00:00:00 UTC 2013
Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis.
Infection and immunity
Scalfone LK,Nel HJ,Gagliardo LF,Cameron JL,Al-Shokri S,Leifer CA,Fallon PG,Appleton JA
14-7133 was used in an ELISA assay to investigate the role in immunity of innate receptors for potential pathogen- or danger-associated molecular patterns.
Mon Apr 01 00:00:00 UTC 2013
Bacterial colonization dampens influenza-mediated acute lung injury via induction of M2 alveolar macrophages.
Nature communications
Wang J,Li F,Sun R,Gao X,Wei H,Li LJ,Tian Z
Published figure using IL-13 monoclonal antibody (Product # 14-7133-81) in Neutralization
Mon Dec 30 00:00:00 UTC 2013
Role of arginase 1 from myeloid cells in th2-dominated lung inflammation.
PloS one
Barron L,Smith AM,El Kasmi KC,Qualls JE,Huang X,Cheever A,Borthwick LA,Wilson MS,Murray PJ,Wynn TA
14-7133 was used in Flow cytometry/Cell sorting to investigate the contribution of arginase 1 to asthma pathogenesis.
Mon Dec 09 00:00:00 UTC 2013
Transcription factor RORα is critical for nuocyte development.
Nature immunology
Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN
14-7133 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.
Sun Jan 22 00:00:00 UTC 2012
Transcription factor RORα is critical for nuocyte development.
Nature immunology
Wong SH,Walker JA,Jolin HE,Drynan LF,Hams E,Camelo A,Barlow JL,Neill DR,Panova V,Koch U,Radtke F,Hardman CS,Hwang YY,Fallon PG,McKenzie AN
14-7133 was used in Flow cytometry/Cell sorting to study how nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, indicating they are a distinct, previously unknown member of the lymphoid lineage.
Sun Jan 22 00:00:00 UTC 2012
Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3.
Journal of immunology (Baltimore, Md. : 1950)
Kim S,Prout M,Ramshaw H,Lopez AF,LeGros G,Min B
14-7133 was used in Flow cytometry/Cell sorting to investigate the importance of IL-3 in recruiting basophils into the draining lymph nodes and inducing Th2 immune responses following helminth infection.
Mon Feb 01 00:00:00 UTC 2010
MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.
Nature immunology
Perrigoue JG,Saenz SA,Siracusa MC,Allenspach EJ,Taylor BC,Giacomin PR,Nair MG,Du Y,Zaph C,van Rooijen N,Comeau MR,Pearce EJ,Laufer TM,Artis D
14-7133 was used in an ELISA assay to suggest that major histocompatibility complex class II-dependent interactions between basophils and CD4+ T cells promote T helper type 2 cytokine responses and immunity to helminth infection.
Wed Jul 01 00:00:00 UTC 2009
