Product References
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis.
Neural regeneration research
Liu C,Guo S,Liu R,Guo M,Wang Q,Chai Z,Xiao B,Ma C
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Mar 01 00:00:00 UTC 2024
Identification of gut dysbiosis in axial spondyloarthritis patients and improvement of experimental ankylosing spondyloarthritis by microbiome-derived butyrate with immune-modulating function.
Frontiers in immunology
Min HK,Na HS,Jhun J,Lee SY,Choi SS,Park GE,Lee JS,Um IG,Lee SY,Seo H,Shin TS,Kim YK,Lee JJ,Kwok SK,Cho ML,Park SH
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon May 08 00:00:00 UTC 2023
Fermented cordyceps powder alleviates silica-induced pulmonary inflammation and fibrosis in rats by regulating the Th immune response.
Chinese medicine
Pu S,Yang Z,Zhang X,Li M,Han N,Yang X,He J,Yu G,Meng X,Jia Q,Shao H
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Oct 12 00:00:00 UTC 2023
Systemic Administration of Acazicolcept, a Dual CD28 and Inducible T cell Costimulator Inhibitor, Ameliorates Experimental Autoimmune Uveitis.
Translational vision science & technology
Wilson L,Lewis KE,Evans LS,Dillon SR,Pepple KL
11-7177-81 was used in Flow cytometry/Cell sorting to evaluate preclinical efficacy using experimental autoimmune uveitis (EAU) in Lewis rats.
Wed Mar 01 00:00:00 UTC 2023
SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis.
Cell communication and signaling : CCS
Lee AR,Woo JS,Lee SY,Lee YS,Jung J,Lee CR,Park SH,Cho ML
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Mar 02 00:00:00 UTC 2023
The Potential of Dendritic-Cell-Based Vaccines to Modulate Type 3 Innate Lymphoid Cell Populations.
International journal of molecular sciences
Chan L,Mehrani Y,Minott JA,Bridle BW,Karimi K
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Jan 26 00:00:00 UTC 2023
Mechanism of miR-181a-5p in Regulatory T/T-Helper 17 Immune Imbalance and Asthma Development in Mice with Allergic Rhinitis.
International archives of allergy and immunology
He R,Chen Y,Chen X,Yuan B
11-7177-81 was used in Flow cytometry/Cell sorting to reveal that miR-181a-5p overexpression reduced the binding of HMGB1 and RAGE by inhibiting HMGB1, thus alleviating Treg/Th17 immune imbalance and blocking AR from developing into asthma.
Tue Apr 05 00:00:00 UTC 2022
Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element.
Immunity
Hall JA,Pokrovskii M,Kroehling L,Kim BR,Kim SY,Wu L,Lee JY,Littman DR
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Nov 08 00:00:00 UTC 2022
Free Fatty Acid Receptor 4 (FFA4) Activation Ameliorates Imiquimod-Induced Psoriasis in Mice.
International journal of molecular sciences
Son SE,Koh JM,Im DS
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Apr 19 00:00:00 UTC 2022
EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis.
Arthritis research & therapy
Park JS,Yang SC,Jeong HY,Lee SY,Ryu JG,Choi JW,Kang HY,Kim SM,Hwang SH,Cho ML,Park SH
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Nov 17 00:00:00 UTC 2022
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators.
Nature communications
Dong X,Guthrie BGH,Alexander M,Noecker C,Ramirez L,Glasser NR,Turnbaugh PJ,Balskus EP
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Dec 09 00:00:00 UTC 2022
Ursolic acid inhibits Th17 cell differentiation via STAT3/RORγt pathway and suppresses Schwann cell-mediated Th17 cell migration by reducing CXCL9/10 expression.
Innate immunity
Xu H,Yu AL,Zhao DP,Meng GY,Wang L,Shan M,Hu NX,Liu YL
11-7177-81 was used in Flow cytometry/Cell sorting to explore the effects of UA on Th17 cell differentiation and Schwann cell(SCs)-mediated migration and the potential mechanism.
Fri Jul 01 00:00:00 UTC 2022
Estrogen Protects against Renal Ischemia-Reperfusion Injury by Regulating Th17/Treg Cell Immune Balance.
Disease markers
Zhang Y,Chang Y,Han Z,Ma K,Zeng X,Li L
11-7177-81 was used in Flow Cytometry to indicate that Cx43 may participate in the regulation of Th17/Treg balance by estrogen against renal IRI.
Tue Oct 18 00:00:00 UTC 2022
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
EMBO reports
Lopez Krol A,Nehring HP,Krause FF,Wempe A,Raifer H,Nist A,Stiewe T,Bertrams W,Schmeck B,Luu M,Leister H,Chung HR,Bauer UM,Adhikary T,Visekruna A
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Dec 06 00:00:00 UTC 2022
Intrapulmonary Vaccination Induces Long-lasting and Effective Pulmonary Immunity Against Staphylococcus aureus Pneumonia.
The Journal of infectious diseases
Fan X,Li N,Xu M,Yang D,Wang B
11-7177-81 was used in Flow Cytometry to suggest that an intrapulmonary vaccine provides optimal and long-term protection against Staphylococcus aureus pneumonia.
Wed Sep 01 00:00:00 UTC 2021
Trichinella spiralis Paramyosin Induces Colonic Regulatory T Cells to Mitigate Inflammatory Bowel Disease.
Frontiers in cell and developmental biology
Hao C,Wang W,Zhan B,Wang Z,Huang J,Sun X,Zhu X
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Aug 03 00:00:00 UTC 2021
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
11-7177-81 was used in Flow Cytometry to investigate whether the tolerogenic potential of immunodominant myelin T-cell epitopes can be improved by conjugation to the synthetic carrier polyethylene glycol (PEG) in an experimental autoimmune encephalomyelitis (EAE) mouse model for chronic MS (MOG C57BL/6).
Tue Nov 07 00:00:00 UTC 2023
Prevention of EAE by tolerogenic vaccination with PEGylated antigenic peptides.
Therapeutic advances in chronic disease
Pfeil J,Simonetti M,Lauer U,von Thülen B,Durek P,Poulsen C,Pawlowska J,Kröger M,Krähmer R,Leenders F,Hoffmann U,Hamann A
11-7177-81 was used in Flow Cytometry to investigate whether the tolerogenic potential of immunodominant myelin T-cell epitopes can be improved by conjugation to the synthetic carrier polyethylene glycol (PEG) in an experimental autoimmune encephalomyelitis (EAE) mouse model for chronic MS (MOG C57BL/6).
Tue Nov 07 00:00:00 UTC 2023
The Severity of CVB3-Induced Myocarditis Can Be Improved by Blocking the Orchestration of NLRP3 and Th17 in Balb/c Mice.
Mediators of inflammation
Chen J,Yang F,Shi S,Liu X,Qin F,Wei X,Huang Y,Liang W,Miao L
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Immunohistochemistry
Wed Dec 22 00:00:00 UTC 2021
Preliminary analysis of immunoregulatory mechanism of hyperhomocysteinemia-induced brain injury in Wistar-Kyoto rats.
Experimental and therapeutic medicine
Zhang Y,Wang L,Li X,Geng J
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Sat May 01 00:00:00 UTC 2021
G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators.
Nature communications
Gurusamy M,Tischner D,Shao J,Klatt S,Zukunft S,Bonnavion R,Günther S,Siebenbrodt K,Kestner RI,Kuhlmann T,Fleming I,Offermanns S,Wettschureck N
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Nov 23 00:00:00 UTC 2021
Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling.
Drug design, development and therapy
Guo Q,Qu H,Zhang H,Zhong X
11-7177-81 was used in Flow Cytometry, Immunohistochemistry (Paraffin) to show that Prunella vulgaris L. attenuated the high-mobility group box-1-induced increases in Th1, Th2 and Th17 cells in AIT models, providing new evidence for the potential therapeutic value of PV as a treatment for AIT and other autoimmune diseases.
Tue Feb 22 00:00:00 UTC 2022
Prunella vulgaris L. Attenuates Experimental Autoimmune Thyroiditis by Inhibiting HMGB1/TLR9 Signaling.
Drug design, development and therapy
Guo Q,Qu H,Zhang H,Zhong X
11-7177-81 was used in Flow Cytometry, Immunohistochemistry (Paraffin) to show that Prunella vulgaris L. attenuated the high-mobility group box-1-induced increases in Th1, Th2 and Th17 cells in AIT models, providing new evidence for the potential therapeutic value of PV as a treatment for AIT and other autoimmune diseases.
Tue Feb 22 00:00:00 UTC 2022
ILC3s control airway inflammation by limiting T cell responses to allergens and microbes.
Cell reports
Teng F,Tachó-Piñot R,Sung B,Farber DL,Worgall S,Hammad H,Lambrecht BN,Hepworth MR,Sonnenberg GF
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in ELISA
Tue Nov 23 00:00:00 UTC 2021
Positive Effects of Oral Antibiotic Administration in Murine Chronic Graft-Versus-Host Disease.
International journal of molecular sciences
Sato S,Shimizu E,He J,Ogawa M,Asai K,Yazu H,Rusch R,Yamane M,Yang F,Fukuda S,Kawakami Y,Tsubota K,Ogawa Y
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Immunohistochemistry
Sat Apr 03 00:00:00 UTC 2021
In Vivo Induction of Regulatory T Cells Via CTLA-4 Signaling Peptide to Control Autoimmune Encephalomyelitis and Prevent Disease Relapse.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Kim GR,Kim WJ,Lim S,Lee HG,Koo JH,Nam KH,Kim SM,Park SD,Choi JM
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Jul 01 00:00:00 UTC 2021
The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine response.
Nature communications
Liu B,Huang J,Ashraf A,Rahaman O,Lou J,Wang L,Cai P,Wen J,Anwaar S,Liu X,Ni H,Ganguly D,Zhao J,Yang CY
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Jul 02 00:00:00 UTC 2021
Intestinal barrier dysfunction plays an integral role in arthritis pathology and can be targeted to ameliorate disease.
Med (New York, N.Y.)
Matei DE,Menon M,Alber DG,Smith AM,Nedjat-Shokouhi B,Fasano A,Magill L,Duhlin A,Bitoun S,Gleizes A,Hacein-Bey-Abina S,Manson JJ,Rosser EC,Klein N,Blair PA,Mauri C
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Jul 09 00:00:00 UTC 2021
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry.
STAR protocols
Skordos I,Demeyer A,Beyaert R
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Mar 19 00:00:00 UTC 2021
Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity.
Cell metabolism
Angiari S,Runtsch MC,Sutton CE,Palsson-McDermott EM,Kelly B,Rana N,Kane H,Papadopoulou G,Pearce EL,Mills KHG,O'Neill LAJ
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Feb 04 00:00:00 UTC 2020
The colonic macrophage transcription factor RBP-J orchestrates intestinal immunity against bacterial pathogens.
The Journal of experimental medicine
Kang L,Zhang X,Ji L,Kou T,Smith SM,Zhao B,Guo X,Pineda-Torra I,Wu L,Hu X
11-7177-81 was used in Flow Cytometry to demonstrate that colonic macrophage-intrinsic RBP-J dynamically orchestrates intestinal immunity against pathogen infections by interfacing with key immune cells of T and innate lymphoid cell lineages.
Mon Apr 06 00:00:00 UTC 2020
GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells.
Immune network
Moon J,Lee SH,Lee SY,Ryu J,Jhun J,Choi J,Kim GN,Roh S,Park SH,Cho ML
11-7177 was used in Immunohistochemistry to explore whether GRIM-19 ameliorated MS by increasing the levels of inflammatory cytokines and immune cells.
Thu Oct 01 00:00:00 UTC 2020
GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells.
Immune network
Moon J,Lee SH,Lee SY,Ryu J,Jhun J,Choi J,Kim GN,Roh S,Park SH,Cho ML
11-7177 was used in Immunohistochemistry to explore whether GRIM-19 ameliorated MS by increasing the levels of inflammatory cytokines and immune cells.
Thu Oct 01 00:00:00 UTC 2020
GRIM-19 Ameliorates Multiple Sclerosis in a Mouse Model of Experimental Autoimmune Encephalomyelitis with Reciprocal Regulation of IFNγ/Th1 and IL-17A/Th17 Cells.
Immune network
Moon J,Lee SH,Lee SY,Ryu J,Jhun J,Choi J,Kim GN,Roh S,Park SH,Cho ML
11-7177 was used in Immunohistochemistry to explore whether GRIM-19 ameliorated MS by increasing the levels of inflammatory cytokines and immune cells.
Thu Oct 01 00:00:00 UTC 2020
IL-17A-producing T cells exacerbate fine particulate matter-induced lung inflammation and fibrosis by inhibiting PI3K/Akt/mTOR-mediated autophagy.
Journal of cellular and molecular medicine
Cong LH,Li T,Wang H,Wu YN,Wang SP,Zhao YY,Zhang GQ,Duan J
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Sat Aug 01 00:00:00 UTC 2020
Exploring the Mechanism on the Medullary Visceral Zone Inhibiting the Cholinergic Anti-inflammatory Pathway Induced by Sepsis.
Mediators of inflammation
Li HB,Zhou Y,Zhao AH,Guo LL
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Aug 02 00:00:00 UTC 2021
Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol-Related Liver Disease.
Alcoholism, clinical and experimental research
Marrero I,Maricic I,Morgan TR,Stolz AA,Schnabl B,Liu ZX,Tsukamoto H,Kumar V
11-7177-81 was used in Flow Cytometry to investigate the role of innate-like unconventional T cells in alcohol-related liver disease.
Fri May 01 00:00:00 UTC 2020
Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development.
Cell reports
Ramstead AG,Wallace JA,Lee SH,Bauer KM,Tang WW,Ekiz HA,Lane TE,Cluntun AA,Bettini ML,Round JL,Rutter J,O'Connell RM
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Mar 03 00:00:00 UTC 2020
M1 Macrophage Derived Exosomes Aggravate Experimental Autoimmune Neuritis via Modulating Th1 Response.
Frontiers in immunology
Du T,Yang CL,Ge MR,Liu Y,Zhang P,Li H,Li XL,Li T,Liu YD,Dou YC,Yang B,Duan RS
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Apr 13 00:00:00 UTC 2021
UCP3 reciprocally controls CD4+ Th17 and Treg cell differentiation.
PloS one
O'Connor EB,Muñoz-Wolf N,Leon G,Lavelle EC,Mills KHG,Walsh PT,Porter RK
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Jan 07 00:00:00 UTC 2021
FUT1 deficiency elicits immune dysregulation and corneal opacity in steady state and under stress.
Cell death & disease
Kim KW,Ryu JS,Ko JH,Kim JY,Kim HJ,Lee HJ,Oh JH,Chung JH,Oh JY
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Apr 24 00:00:00 UTC 2020
Lactobacillus reuteri 5454 and Bifidobacterium animalis ssp. lactis 5764 improve colitis while differentially impacting dendritic cells maturation and antimicrobial responses.
Scientific reports
Hrdý J,Alard J,Couturier-Maillard A,Boulard O,Boutillier D,Delacre M,Lapadatescu C,Cesaro A,Blanc P,Pot B,Ryffel B,Chamaillard M,Grangette C
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Mar 24 00:00:00 UTC 2020
Lactobacillus rhamnosus GG attenuates tenofovir disoproxil fumarate-induced bone loss in male mice via gut-microbiota-dependent anti-inflammation.
Therapeutic advances in chronic disease
Liu H,Gu R,Li W,Zhou W,Cong Z,Xue J,Liu Y,Wei Q,Zhou Y
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Sat Apr 09 00:00:00 UTC 2022
Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway.
Mediators of inflammation
Xu Y,Tang X,Yang M,Zhang S,Li S,Chen Y,Liu M,Guo Y,Lu M
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Jun 11 00:00:00 UTC 2019
IL-31 plays dual roles in lung inflammation in an OVA-induced murine asthma model.
Biology open
Huang J,Yue H,Jiang T,Gao J,Shi Y,Shi B,Wu X,Gou X
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Jan 15 00:00:00 UTC 2019
Therapeutic effect of gold nanoparticles on DSS-induced ulcerative colitis in mice with reference to interleukin-17 expression.
Scientific reports
Abdelmegid AM,Abdo FK,Ahmed FE,Kattaia AAA
11-7177-81 was used in Immunohistochemistry to show the therapeutic potential of gold nanoparticles on dextran sodium sulphate-induced ulcerative colitis in mice.
Mon Jul 15 00:00:00 UTC 2019
Therapeutic effect of gold nanoparticles on DSS-induced ulcerative colitis in mice with reference to interleukin-17 expression.
Scientific reports
Abdelmegid AM,Abdo FK,Ahmed FE,Kattaia AAA
11-7177-81 was used in Immunohistochemistry to show the therapeutic potential of gold nanoparticles on dextran sodium sulphate-induced ulcerative colitis in mice.
Mon Jul 15 00:00:00 UTC 2019
A Macrophage Colony-Stimulating-Factor-Producing γδ T Cell Subset Prevents Malarial Parasitemic Recurrence.
Immunity
Mamedov MR,Scholzen A,Nair RV,Cumnock K,Kenkel JA,Oliveira JHM,Trujillo DL,Saligrama N,Zhang Y,Rubelt F,Schneider DS,Chien YH,Sauerwein RW,Davis MM
11-7177-81 was used in Flow Cytometry to point to an M-CSF-producing γδ T cell subset that fulfills a specialized protective role in the later stage of malaria infection when αβ T cells have declined.
Tue Feb 20 00:00:00 UTC 2018
Bryostatin-1 alleviates experimental multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Kornberg MD,Smith MD,Shirazi HA,Calabresi PA,Snyder SH,Kim PM
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Feb 27 00:00:00 UTC 2018
RKIP mediates autoimmune inflammation by positively regulating IL-17R signaling.
EMBO reports
Lin W,Wang N,Zhou K,Su F,Jiang Y,Shou J,Liu H,Ma C,Qian Y,Wang K,Wang X
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Jun 01 00:00:00 UTC 2018
RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis.
Frontiers in immunology
Manresa-Arraut A,Johansen FF,Brakebusch C,Issazadeh-Navikas S,Hasseldam H
Tue Aug 13 00:00:00 UTC 2019
MicroRNA-126 deficiency enhanced the activation and function of CD4+ T cells by elevating IRS-1 pathway.
Clinical and experimental immunology
Chu F,Hu Y,Zhou Y,Guo M,Lu J,Zheng W,Xu H,Zhao J,Xu L
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Feb 01 00:00:00 UTC 2018
Effects of different principles of Traditional Chinese Medicine treatment on TLR7/NF-κB signaling pathway in influenza virus infected mice.
Chinese medicine
Fu YJ,Yan YQ,Qin HQ,Wu S,Shi SS,Zheng X,Wang PC,Chen XY,Tang XL,Jiang ZY
11-7177 was used in Flow cytometry/Cell sorting to show traditional chinese medicines Guizhi-and-Mahuang decoction and Yinqiao powder can provide anti-influenza functions.
Mon Mar 21 00:00:00 UTC 2022
Combined treatment with simvastatin and rapamycin attenuates cardiac allograft rejection through the regulation of T helper 17 and regulatory T cells.
Experimental and therapeutic medicine
Liu Y,Sun L,Chen W,Chuai J,Shang Y,Zhang D,Fu B,Tian H,Jiang S
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Feb 01 00:00:00 UTC 2018
Baicalin Downregulates RLRs Signaling Pathway to Control Influenza A Virus Infection and Improve the Prognosis.
Evidence-based complementary and alternative medicine : eCAM
Pang P,Zheng K,Wu S,Xu H,Deng L,Shi Y,Chen X
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Oct 01 00:00:00 UTC 2020
Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.
JCI insight
Moreno-Fernandez ME,Giles DA,Stankiewicz TE,Sheridan R,Karns R,Cappelletti M,Lampe K,Mukherjee R,Sina C,Sallese A,Bridges JP,Hogan SP,Aronow BJ,Hoebe K,Divanovic S
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in ELISA
Thu Mar 22 00:00:00 UTC 2018
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.
eLife
Lian G,Gnanaprakasam JR,Wang T,Wu R,Chen X,Liu L,Shen Y,Yang M,Yang J,Chen Y,Vasiliou V,Cassel TA,Green DR,Liu Y,Fan TW,Wang R
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Sep 10 00:00:00 UTC 2018
Vibrio vulnificus RtxA Is a Major Factor Driving Inflammatory T Helper Type 17 Cell Responses in vitro and in vivo.
Frontiers in immunology
Lee A,Kim MS,Cho D,Jang KK,Choi SH,Kim TS
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Sep 30 00:00:00 UTC 2019
ITGB4 deficiency in bronchial epithelial cells directs airway inflammation and bipolar disorder-related behavior.
Journal of neuroinflammation
Han L,Wang L,Tang S,Yuan L,Wu S,Du X,Xiang Y,Qu X,Liu H,Luo H,Qin X,Liu C
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Aug 31 00:00:00 UTC 2018
Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation.
Nature communications
Li H,Yao Q,Mariscal AG,Wu X,Hülse J,Pedersen E,Helin K,Waisman A,Vinkel C,Thomsen SF,Avgustinova A,Benitah SA,Lovato P,Norsgaard H,Mortensen MS,Veng L,Rozell B,Brakebusch C
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Apr 12 00:00:00 UTC 2018
γδ T cells control humoral immune response by inducing T follicular helper cell differentiation.
Nature communications
Rezende RM,Lanser AJ,Rubino S,Kuhn C,Skillin N,Moreira TG,Liu S,Gabriely G,David BA,Menezes GB,Weiner HL
11-7177 was used in Flow cytometry/Cell sorting to demonstrate that complete Freund's adjuvant immunisation induces a subpopulation of CXCR5-expressing γδ T cells in the draining lymph nodes.
Wed Aug 08 00:00:00 UTC 2018
Maternal gut bacteria promote neurodevelopmental abnormalities in mouse offspring.
Nature
Kim S,Kim H,Yim YS,Ha S,Atarashi K,Tan TG,Longman RS,Honda K,Littman DR,Choi GB,Huh JR
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Sep 28 00:00:00 UTC 2017
miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity.
The Journal of clinical investigation
Li B,Wang X,Choi IY,Wang YC,Liu S,Pham AT,Moon H,Smith DJ,Rao DS,Boldin MP,Yang L
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Oct 02 00:00:00 UTC 2017
Microbial, metabolomic, and immunologic dynamics in a relapsing genetic mouse model of colitis induced by T-synthase deficiency.
Gut microbes
Jacobs JP,Lin L,Goudarzi M,Ruegger P,McGovern DP,Fornace AJ,Borneman J,Xia L,Braun J
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Jan 02 00:00:00 UTC 2017
Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis.
Mucosal immunology
Qi X,Gurung P,Malireddi RK,Karmaus PW,Sharma D,Vogel P,Chi H,Green DR,Kanneganti TD
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Sun Jan 01 00:00:00 UTC 2017
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Webb LM,Amici SA,Jablonski KA,Savardekar H,Panfil AR,Li L,Zhou W,Peine K,Karkhanis V,Bachelder EM,Ainslie KM,Green PL,Li C,Baiocchi RA,Guerau-de-Arellano M
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in ELISA
Wed Feb 15 00:00:00 UTC 2017
PRMT5-Selective Inhibitors Suppress Inflammatory T Cell Responses and Experimental Autoimmune Encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950)
Webb LM,Amici SA,Jablonski KA,Savardekar H,Panfil AR,Li L,Zhou W,Peine K,Karkhanis V,Bachelder EM,Ainslie KM,Green PL,Li C,Baiocchi RA,Guerau-de-Arellano M
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in ELISA
Wed Feb 15 00:00:00 UTC 2017
Placenta‑derived mesenchymal stem cells improve airway hyperresponsiveness and inflammation in asthmatic rats by modulating the Th17/Treg balance.
Molecular medicine reports
Li Y,Li H,Cao Y,Wu F,Ma W,Wang Y,Sun S
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Dec 01 00:00:00 UTC 2017
Upregulation of SOCS3 in lung CD4+ T cells in a mouse model of chronic PA lung infection and suppression of Th17‑mediated neutrophil recruitment in exogenous SOCS3 transfer in vitro.
Molecular medicine reports
Ding FM,Liao RM,Chen YQ,Xie GG,Zhang PY,Shao P,Zhang M
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Sat Jul 01 00:00:00 UTC 2017
Microsomal Prostaglandin E Synthase-1 Facilitates an Intercellular Interaction between CD4⁺ T Cells through IL-1β Autocrine Function in Experimental Autoimmune Encephalomyelitis.
International journal of molecular sciences
Takemiya T,Takeuchi C,Kawakami M
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Immunofluorescence
Tue Dec 19 00:00:00 UTC 2017
Essential role for CCR6 in certain inflammatory diseases demonstrated using specific antagonist and knockin mice.
JCI insight
Robert R,Ang C,Sun G,Juglair L,Lim EX,Mason LJ,Payne NL,Bernard CC,Mackay CR
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Aug 03 00:00:00 UTC 2017
Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.
Scientific reports
Zhang H,Qi Y,Yuan Y,Cai L,Xu H,Zhang L,Su B,Nie H
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Feb 06 00:00:00 UTC 2017
Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation.
JCI insight
Tischner D,Grimm M,Kaur H,Staudenraus D,Carvalho J,Looso M,Günther S,Wanke F,Moos S,Siller N,Breuer J,Schwab N,Zipp F,Waisman A,Kurschus FC,Offermanns S,Wettschureck N
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Aug 03 00:00:00 UTC 2017
Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
Nature communications
Deng R,Hurtz C,Song Q,Yue C,Xiao G,Yu H,Wu X,Muschen M,Forman S,Martin PJ,Zeng D
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Oct 17 00:00:00 UTC 2017
Traditional Herbal Medicine-Derived Sulforaphene LFS-01 Reverses Colitis in Mice by Selectively Altering the Gut Microbiota and Promoting Intestinal Gamma-Delta T Cells.
Frontiers in pharmacology
Li M,Gao J,Tang Y,Liu M,Wu S,Qu K,Long X,Li H,Liu M,Liu Y,Yuan J,Mao L,Liu Y,Zheng X,Wang E,Wang J,Yang Y
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Wed Sep 30 00:00:00 UTC 2020
Batf3-dependent CD8α+ Dendritic Cells Aggravates Atherosclerosis via Th1 Cell Induction and Enhanced CCL5 Expression in Plaque Macrophages.
EBioMedicine
Li Y,Liu X,Duan W,Tian H,Zhu G,He H,Yao S,Yi S,Song W,Tang H
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Sat Apr 01 00:00:00 UTC 2017
Oral administration of taheebo (Tabebuia avellanedae Lorentz ex Griseb.) water extract prevents DSS-induced colitis in mice by up-regulating type II T helper immune responses.
BMC complementary and alternative medicine
Park HJ,Lee SW,Kwon DJ,Heo SI,Park SH,Kim SY,Hong S
11-7177 was used in Flow cytometry/Cell sorting to show that taheebo water extract (TWE) is an excellent natural product with therapeutic effects to help improve inflammatory disorders such as colitis.
Wed Sep 06 00:00:00 UTC 2017
Host-Protozoan Interactions Protect from Mucosal Infections through Activation of the Inflammasome.
Cell
Chudnovskiy A,Mortha A,Kana V,Kennard A,Ramirez JD,Rahman A,Remark R,Mogno I,Ng R,Gnjatic S,Amir ED,Solovyov A,Greenbaum B,Clemente J,Faith J,Belkaid Y,Grigg ME,Merad M
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Oct 06 00:00:00 UTC 2016
Oligodendrocyte death results in immune-mediated CNS demyelination.
Nature neuroscience
Traka M,Podojil JR,McCarthy DP,Miller SD,Popko B
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis.
Annals of the rheumatic diseases
Chen L,Ridley A,Hammitzsch A,Al-Mossawi MH,Bunting H,Georgiadis D,Chan A,Kollnberger S,Bowness P
11-7177 was used in Flow cytometry/Cell sorting to study the effects of silencing endoplasmic reticulum aminopeptidase 1 (ERAP1) on human leucocyte antigen (HLA)-B27 free heavy chain expression and Th17 responses in ankylosing spondylitis.
Sun May 01 00:00:00 UTC 2016
Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.
Science translational medicine
Dendrou CA,Cortes A,Shipman L,Evans HG,Attfield KE,Jostins L,Barber T,Kaur G,Kuttikkatte SB,Leach OA,Desel C,Faergeman SL,Cheeseman J,Neville MJ,Sawcer S,Compston A,Johnson AR,Everett C,Bell JI,Karpe F,Ultsch M,Eigenbrot C,McVean G,Fugger L
11-7177 was used in Flow cytometry/Cell sorting to reveal a protective homozygous effect that defined a signalling optimum between autoimmunity and immunodeficiency and identified TYK2 as a potential drug target for autoimmune disorders.
Wed Nov 02 00:00:00 UTC 2016
Autophagy deficiency in myeloid cells increases susceptibility to obesity-induced diabetes and experimental colitis.
Autophagy
Lee HY,Kim J,Quan W,Lee JC,Kim MS,Kim SH,Bae JW,Hur KY,Lee MS
11-7177 was used in Flow cytometry/Cell sorting to investigate how autophagy of MΦs is important for the control of inflammasome activation in response to metabolic or extrinsic stress.
Tue Aug 02 00:00:00 UTC 2016
p(⁷⁰S⁶K¹) in the TORC1 pathway is essential for the differentiation of Th17 Cells, but not Th1, Th2, or Treg cells in mice.
European journal of immunology
Sasaki CY,Chen G,Munk R,Eitan E,Martindale J,Longo DL,Ghosh P
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Jan 01 00:00:00 UTC 2016
Nuclear receptor expression atlas in BMDCs: Nr4a2 restricts immunogenicity of BMDCs and impedes EAE.
European journal of immunology
Saini A,Mahajan S,Gupta P
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
Rapamycin ameliorates CCl4-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance.
Molecular medicine reports
Gu L,Deng WS,Sun XF,Zhou H,Xu Q
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
Age-dependent divergent effects of OX40L treatment on the development of diabetes in NOD mice.
Autoimmunity
Haddad CS,Bhattacharya P,Alharshawi K,Marinelarena A,Kumar P,El-Sayed O,Elshabrawy HA,Epstein AL,Prabhakar BS
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Aug 01 00:00:00 UTC 2016
Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy.
Scientific reports
Kue CS,Kamkaew A,Voon SH,Kiew LV,Chung LY,Burgess K,Lee HB
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Thu Nov 17 00:00:00 UTC 2016
Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.
Nature communications
Baptista MA,Keszei M,Oliveira M,Sunahara KK,Andersson J,Dahlberg CI,Worth AJ,Liedén A,Kuo IC,Wallin RP,Snapper SB,Eidsmo L,Scheynius A,Karlsson MC,Bouma G,Burns SO,Forsell MN,Thrasher AJ,Nylén S,Westerberg LS
11-7177 was used in Immunohistochemistry to study the balance between activation of WASp and Rac2 signalling pathways in dendritic cells.
Mon Jul 18 00:00:00 UTC 2016
Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.
Nature communications
Baptista MA,Keszei M,Oliveira M,Sunahara KK,Andersson J,Dahlberg CI,Worth AJ,Liedén A,Kuo IC,Wallin RP,Snapper SB,Eidsmo L,Scheynius A,Karlsson MC,Bouma G,Burns SO,Forsell MN,Thrasher AJ,Nylén S,Westerberg LS
11-7177 was used in Immunohistochemistry to study the balance between activation of WASp and Rac2 signalling pathways in dendritic cells.
Mon Jul 18 00:00:00 UTC 2016
B cell-derived transforming growth factor-β1 expression limits the induction phase of autoimmune neuroinflammation.
Scientific reports
Bjarnadóttir K,Benkhoucha M,Merkler D,Weber MS,Payne NL,Bernard CCA,Molnarfi N,Lalive PH
11-7177-81 was used in Flow Cytometry to test the role for transforming growth factor-β1 expression in regulatory B cell function in autoimmune neuroinflammation.
Thu Oct 06 00:00:00 UTC 2016
Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis.
PloS one
Alves da Costa T,Di Gangi R,Thomé R,Barreto Felisbino M,Pires Bonfanti A,Lumi Watanabe Ishikawa L,Sartori A,Burger E,Verinaud L
11-7177 was used in Flow cytometry/Cell sorting to develop a new experimental model where Pb yeast cells are injected through the intraperitoneal route and mice are evaluated over 120 days of infection.
Mon May 22 00:00:00 UTC 2017
HtrA2 suppresses autoimmune arthritis and regulates activation of STAT3.
Scientific reports
Lee SH,Moon YM,Seo HB,Kim SY,Kim EK,Yi J,Nam MK,Min JK,Park SH,Rhim H,Cho ML
11-7177 was used in Flow cytometry/Cell sorting to study the suppression of autoimmune arthritis and regulation of STAT3 activation via HtrA2.
Fri Dec 23 00:00:00 UTC 2016
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Nature biotechnology
Chen HJ,Sun J,Huang Z,Hou H,Arcilla M,Rakhilin N,Joe DJ,Choi J,Gadamsetty P,Milsom J,Nandakumar G,Longman R,Zhou XK,Edwards R,Chen J,Chen KY,Bu P,Wang L,Xu Y,Munroe R,Abratte C,Miller AD,Gümüş ZH,Shuler M,Nishimura N,Edelmann W,Shen X,Lipkin SM
11-7177 was used in Flow cytometry/Cell sorting to create chemokine-targeted mouse models that recapitulate the majority of common human somatic CRC mutations.
Mon Jun 01 00:00:00 UTC 2015
Tamm-Horsfall Protein Regulates Granulopoiesis and Systemic Neutrophil Homeostasis.
Journal of the American Society of Nephrology : JASN
Micanovic R,Chitteti BR,Dagher PC,Srour EF,Khan S,Hato T,Lyle A,Tong Y,Wu XR,El-Achkar TM
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Sep 01 00:00:00 UTC 2015
Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination.
Molecular psychiatry
Choi EY,Lim JH,Neuwirth A,Economopoulou M,Chatzigeorgiou A,Chung KJ,Bittner S,Lee SH,Langer H,Samus M,Kim H,Cho GS,Ziemssen T,Bdeir K,Chavakis E,Koh JY,Boon L,Hosur K,Bornstein SR,Meuth SG,Hajishengallis G,Chavakis T
11-7177 was used in Flow cytometry/Cell sorting to provide mechanistic underpinnings for the previous implication of Del-1 as a candidate MS susceptibility gene.
Wed Jul 01 00:00:00 UTC 2015
MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.
Proceedings of the National Academy of Sciences of the United States of America
Wu L,Li N,Zhang M,Xue SL,Cassady K,Lin Q,Riggs AD,Zeng D
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Dec 29 00:00:00 UTC 2015
Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome.
Journal of immunology (Baltimore, Md. : 1950)
Li JT,Melton AC,Su G,Hamm DE,LaFemina M,Howard J,Fang X,Bhat S,Huynh KM,O'Kane CM,Ingram RJ,Muir RR,McAuley DF,Matthay MA,Sheppard D
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Wed Jul 01 00:00:00 UTC 2015
Female-Specific Downregulation of Tissue Polymorphonuclear Neutrophils Drives Impaired Regulatory T Cell and Amplified Effector T Cell Responses in Autoimmune Dry Eye Disease.
Journal of immunology (Baltimore, Md. : 1950)
Gao Y,Min K,Zhang Y,Su J,Greenwood M,Gronert K
11-7177 was used in Flow cytometry/Cell sorting to investigate the cause of sex-specific prevalence of immune-driven dry eye disease.
Thu Oct 01 00:00:00 UTC 2015
A Multiple Antigenic Peptide Mimicking Peptidoglycan Induced T Cell Responses to Protect Mice from Systemic Infection with Staphylococcus aureus.
PloS one
Wang XY,Huang ZX,Chen YG,Lu X,Zhu P,Wen K,Fu N,Liu BY
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue May 24 00:00:00 UTC 2016
Upregulation of Programmed Death-1 and Its Ligand in Cardiac Injury Models: Interaction with GADD153.
PloS one
Baban B,Liu JY,Qin X,Weintraub NL,Mozaffari MS
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Apr 12 00:00:00 UTC 2016
Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses.
Stem cell reports
Wang WB,Yen ML,Liu KJ,Hsu PJ,Lin MH,Chen PM,Sudhir PR,Chen CH,Chen CH,Sytwu HK,Yen BL
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Sep 08 00:00:00 UTC 2015
Identification and characterization of latency-associated peptide-expressing γδ T cells.
Nature communications
Rezende RM,da Cunha AP,Kuhn C,Rubino S,M'Hamdi H,Gabriely G,Vandeventer T,Liu S,Cialic R,Pinheiro-Rosa N,Oliveira RP,Gaublomme JT,Obholzer N,Kozubek J,Pochet N,Faria AMC,Weiner HL
11-7177 was used in Flow cytometry/Cell sorting to describe a subset of regulatory γδ T cells that express the latency-associated peptide, a membrane-bound TGF-β1.
Tue Dec 08 00:00:00 UTC 2015
Anthocyanin Extracted from Black Soybean Seed Coats Prevents Autoimmune Arthritis by Suppressing the Development of Th17 Cells and Synthesis of Proinflammatory Cytokines by Such Cells, via Inhibition of NF-κB.
PloS one
Min HK,Kim SM,Baek SY,Woo JW,Park JS,Cho ML,Lee J,Kwok SK,Kim SW,Park SH
11-7177 was used in Flow cytometry/Cell sorting to investigate the anti-arthritic effects of anthocyanin extracted from black soybean seed coats in both murine and human cells.
Tue Jun 14 00:00:00 UTC 2016
CX₃CR1⁺ mononuclear phagocytes support colitis-associated innate lymphoid cell production of IL-22.
The Journal of experimental medicine
Longman RS,Diehl GE,Victorio DA,Huh JR,Galan C,Miraldi ER,Swaminath A,Bonneau R,Scherl EJ,Littman DR
11-7177 was used in Flow cytometry/Cell sorting to study the role of CX3CR1+ mononuclear phagocytes in the development of colitis and disease progression following Citrobacter rodentium infection.
Mon Jul 28 00:00:00 UTC 2014
Spironolactone decreases DOCA-salt-induced organ damage by blocking the activation of T helper 17 and the downregulation of regulatory T lymphocytes.
Hypertension (Dallas, Tex. : 1979)
Amador CA,Barrientos V,Peña J,Herrada AA,González M,Valdés S,Carrasco L,Alzamora R,Figueroa F,Kalergis AM,Michea L
11-7177 was used in Flow cytometry/Cell sorting to study the adaptive immune response-induced inflammatory mechanisms contributing to fibrosis.
Tue Apr 01 00:00:00 UTC 2014
Ursolic acid ameliorates autoimmune arthritis via suppression of Th17 and B cell differentiation.
Acta pharmacologica Sinica
Baek SY,Lee J,Lee DG,Park MK,Lee J,Kwok SK,Cho ML,Park SH
11-7177 was used in Flow cytometry/Cell sorting to identify the mechanisms underlying the effects of ursolic acid on collagen-induced arthritis.
Mon Sep 01 00:00:00 UTC 2014
Innate IL-17A-producing leukocytes promote acute kidney injury via inflammasome and Toll-like receptor activation.
The American journal of pathology
Chan AJ,Alikhan MA,Odobasic D,Gan PY,Khouri MB,Steinmetz OM,Mansell AS,Kitching AR,Holdsworth SR,Summers SA
11-7177 was used in Flow cytometry/Cell sorting to investigate the pathogenic role of IL-17A in cisplatin-induced acute kidney injury.
Thu May 01 00:00:00 UTC 2014
Innate PI3K p110δ regulates Th1/Th17 development and microbiota-dependent colitis.
Journal of immunology (Baltimore, Md. : 1950)
Steinbach EC,Kobayashi T,Russo SM,Sheikh SZ,Gipson GR,Kennedy ST,Uno JK,Mishima Y,Borst LB,Liu B,Herfarth H,Ting JP,Sartor RB,Plevy SE
11-7177 was used in Flow cytometry/Cell sorting to explore the role of IL-10 and IL-12/23 in the development of microbiota-dependent colitis.
Tue Apr 15 00:00:00 UTC 2014
A chitin-like component on sclerotic cells of Fonsecaea pedrosoi inhibits Dectin-1-mediated murine Th17 development by masking β-glucans.
PloS one
Dong B,Li D,Li R,Chen SC,Liu W,Liu W,Chen L,Chen Y,Zhang X,Tong Z,Xia Y,Xia P,Wang Y,Duan Y
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Mon Sep 28 00:00:00 UTC 2015
Mycobacterial membrane vesicles administered systemically in mice induce a protective immune response to surface compartments of Mycobacterium tuberculosis.
mBio
Prados-Rosales R,Carreño LJ,Batista-Gonzalez A,Baena A,Venkataswamy MM,Xu J,Yu X,Wallstrom G,Magee DM,LaBaer J,Achkar JM,Jacobs WR,Chan J,Porcelli SA,Casadevall A
Tue Sep 30 00:00:00 UTC 2014
Reduced CD18 levels drive regulatory T cell conversion into Th17 cells in the CD18hypo PL/J mouse model of psoriasis.
Journal of immunology (Baltimore, Md. : 1950)
Singh K,Gatzka M,Peters T,Borkner L,Hainzl A,Wang H,Sindrilaru A,Scharffetter-Kochanek K
11-7177 was used in Flow cytometry/Cell sorting to investigate the influence of adhesion molecules on the differentiation of Foxp3(+) Tregs into proinflammatory Th17 cells occurring in lesional skin and blood of psoriasis patients.
Fri Mar 15 00:00:00 UTC 2013
γδ T cells are essential effectors of type 1 diabetes in the nonobese diabetic mouse model.
Journal of immunology (Baltimore, Md. : 1950)
Markle JG,Mortin-Toth S,Wong AS,Geng L,Hayday A,Danska JS
11-7177 was used in Immunocytochemistry to elucidate the role of various subsets of γδ T cells in a murine model for autoimmune disease.
Sat Jun 01 00:00:00 UTC 2013
R-phycoerythrin-conjugated antibodies are inappropriate for intracellular staining of murine plasma cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Kim MS,Kim TS
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Wed May 01 00:00:00 UTC 2013
Interleukin-22 as a molecular adjuvant facilitates IL-17-producing CD8+ T cell responses against a HBV DNA vaccine in mice.
Human vaccines & immunotherapeutics
Wu B,Zou Q,Hu Y,Wang B
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Tue Oct 01 00:00:00 UTC 2013
IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis.
PloS one
Nakanishi W,Yamaguchi S,Matsuda A,Suzukawa M,Shibui A,Nambu A,Kondo K,Suto H,Saito H,Matsumoto K,Yamasoba T,Nakae S
11-7177 was used in Flow cytometry/Cell sorting to determine that IL-33, but not IL-25, is crucial for the development of house dust mice antigen-induced allergic rhinitis.
Thu Sep 18 00:00:00 UTC 2014
STAT6-dependent regulation of Th9 development.
Journal of immunology (Baltimore, Md. : 1950)
Goswami R,Jabeen R,Yagi R,Pham D,Zhu J,Goenka S,Kaplan MH
Wed Feb 01 00:00:00 UTC 2012
B7-CD28 costimulatory signals control the survival and proliferation of murine and human γδ T cells via IL-2 production.
Journal of immunology (Baltimore, Md. : 1950)
Ribot JC,Debarros A,Mancio-Silva L,Pamplona A,Silva-Santos B
11-7177 was used in Flow cytometry/Cell sorting to show that CD28 signals are required for IL-2-mediated survival and proliferation of both CD27(+) and CD27(-) γδ T cell subsets.
Wed Aug 01 00:00:00 UTC 2012
Lactobacillus gasseri suppresses Th17 pro-inflammatory response and attenuates allergen-induced airway inflammation in a mouse model of allergic asthma.
The British journal of nutrition
Jan RL,Yeh KC,Hsieh MH,Lin YL,Kao HF,Li PH,Chang YS,Wang JY
11-7177 was used in Flow cytometry/Cell sorting to show that oral administration of Lactobacillus gasseri can attenuate symptoms of allergen-induced airway inflammation in a mouse model of asthma.
Sat Jul 14 00:00:00 UTC 2012
Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells.
PloS one
Gong Y,Wang Z,Liang Z,Duan H,Ouyang L,Yu Q,Xu Z,Shen G,Weng X,Wu X
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Fri Jul 19 00:00:00 UTC 2013
Anti-IL-23 antibody blockade of IL-23/IL-17 pathway attenuates airway obliteration in rat orthotopic tracheal transplantation.
International immunopharmacology
Cao H,Lan Q,Shi Q,Zhou X,Liu G,Liu J,Tang G,Qiu C,Qiu C,Xu J,Fan H,Liu Z
Sun May 01 00:00:00 UTC 2011
Epigenetic changes at Il12rb2 and Tbx21 in relation to plasticity behavior of Th17 cells.
Journal of immunology (Baltimore, Md. : 1950)
Bending D,Newland S,Krejcí A,Phillips JM,Bray S,Cooke A
11-7177 was used in Flow cytometry/Cell sorting to examine the epigenetic mechanisms underpinning murine Th17 plasticity in vivo.
Tue Mar 15 00:00:00 UTC 2011
Role of epithelial integrin-linked kinase in promoting intestinal inflammation: effects on CCL2, fibronectin and the T cell repertoire.
BMC immunology
Assi K,Patterson S,Dedhar S,Owen D,Levings M,Salh B
Mon Aug 01 00:00:00 UTC 2011
T cells from Programmed Death-1 deficient mice respond poorly to Mycobacterium tuberculosis infection.
PloS one
Tousif S,Singh Y,Prasad DV,Sharma P,Van Kaer L,Das G
Thu May 12 00:00:00 UTC 2011
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice.
The Journal of clinical investigation
Bending D,De la Peña H,Veldhoen M,Phillips JM,Uyttenhove C,Stockinger B,Cooke A
11-7177 was used in Flow cytometry/Cell sorting to show that purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice, secrete IFN-γ and induce diabetes.
Sun Mar 01 00:00:00 UTC 2009
In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression.
The Journal of experimental medicine
Webster KE,Walters S,Kohler RE,Mrkvan T,Boyman O,Surh CD,Grey ST,Sprent J
11-7177 was used in Flow cytometry/Cell sorting to study the role of T reg cells in the induction of resistance to EAE and long term acceptance of islet allografts.
Mon Apr 13 00:00:00 UTC 2009
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells.
Journal of immunology (Baltimore, Md. : 1950)
Baban B,Chandler PR,Sharma MD,Pihkala J,Koni PA,Munn DH,Mellor AL
Published figure using IL-17A monoclonal antibody (Product # 11-7177-81) in Flow Cytometry
Sat Aug 15 00:00:00 UTC 2009
Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ellestad KK,Tsutsui S,Noorbakhsh F,Warren KG,Yong VW,Pittman QJ,Power C
Wed Jul 01 00:00:00 UTC 2009
