Product References
Peripheral Blood Mononuclear Cells from Patients with Type 1 Diabetes and Diabetic Retinopathy Produce Higher Levels of IL-17A, IL-10 and IL-6 and Lower Levels of IFN-γ-A Pilot Study.
Cells
Obasanmi G,Lois N,Armstrong D,Hombrebueno JMR,Lynch A,Chen M,Xu H
12-7178-42 was used in Flow cytometry/Cell sorting to investigate alterations in inflammatory cytokines in peripheral blood mononuclear cells (PBMCs) in 41 people with type 1 diabetes (T1D), sub-grouped into mild non-proliferative DR (mNPDR; n = 13) and active and inactive (each n = 14) PDR.
Tue Jan 31 00:00:00 UTC 2023
MBL Binding with AhR Controls Th17 Immunity in Silicosis-Associated Lung Inflammation and Fibrosis.
Journal of inflammation research
Liu Y,Zhao N,Xu Q,Deng F,Wang P,Dong L,Lu X,Xia L,Wang M,Chen Z,Zhou J,Zuo D
12-7178-42 was used in Flow cytometry/Cell sorting to suggest that MBL limited the Th17 immunity via controlling the AhR/STAT3 pathway, thus providing new insight into silicosis and other inflammatory diseases in patients with MBL deficiency.
Fri Aug 05 00:00:00 UTC 2022
Cytomegalovirus mediates expansion of IL-15-responsive innate-memory cells with SIV killing function.
The Journal of clinical investigation
Méndez-Lagares G,Chin N,Chang WLW,Lee J,Rosás-Umbert M,Kieu HT,Merriam D,Lu W,Kim S,Adamson L,Brander C,Luciw PA,Barry PA,Hartigan-O'Connor DJ
12-7178-42 was used in Flow Cytometry /test) to investigate the effects of rhesus CMV (RhCMV) on composition and function of the immune system in young macaques.
Mon Aug 02 00:00:00 UTC 2021
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
12-7178 was used in Flow cytometry/Cell sorting to shed light on the potential involvement of peripheral T and B cell immunity against this mycotic infection.
Mon May 31 00:00:00 UTC 2021
Th2 Biased Immunity With Altered B Cell Profiles in Circulation of Patients With Sporotrichosis Caused by Sporothrix globosa.
Frontiers in immunology
Zu J,Yao L,Song Y,Cui Y,Guan M,Chen R,Zhen Y,Li S
12-7178 was used in Flow cytometry/Cell sorting to shed light on the potential involvement of peripheral T and B cell immunity against this mycotic infection.
Mon May 31 00:00:00 UTC 2021
Simian-Human Immunodeficiency Virus SHIV.CH505 Infection of Rhesus Macaques Results in Persistent Viral Replication and Induces Intestinal Immunopathology.
Journal of virology
Bar KJ,Coronado E,Hensley-McBain T,O'Connor MA,Osborn JM,Miller C,Gott TM,Wangari S,Iwayama N,Ahrens CY,Smedley J,Moats C,Lynch RM,Haddad EK,Haigwood NL,Fuller DH,Shaw GM,Klatt NR,Manuzak JA
12-7178-42 was used in Flow cytometry/Cell sorting to evaluate the viral dynamics and immunopathology of SHIV.CH505 in rhesus macaques.
Sun Sep 15 00:00:00 UTC 2019
Tim-3 regulates inflammatory cytokine expression and Th17 cell response induced by monocytes from patients with chronic hepatitis B.
Scandinavian journal of immunology
Wang J,Li C,Fu J,Wang X,Feng X,Pan X
Published figure using IL-17A monoclonal antibody (Product # 12-7178-42) in Flow Cytometry
Wed May 01 00:00:00 UTC 2019
P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes.
The Journal of clinical investigation
D'Addio F,Vergani A,Potena L,Maestroni A,Usuelli V,Ben Nasr M,Bassi R,Tezza S,Dellepiane S,El Essawy B,Iascone M,Iacovoni A,Borgese L,Liu K,Visner G,Dhe-Paganon S,Corradi D,Abdi R,Starling RC,Folli F,Zuccotti GV,Sayegh MH,Heeger PS,Chandraker A,Grigioni F,Fiorina P
Published figure using IL-17A monoclonal antibody (Product # 12-7178-42) in Flow Cytometry
Wed Aug 01 00:00:00 UTC 2018
Intestinal damage precedes mucosal immune dysfunction in SIV infection.
Mucosal immunology
Hensley-McBain T,Berard AR,Manuzak JA,Miller CJ,Zevin AS,Polacino P,Gile J,Agricola B,Cameron M,Hu SL,Estes JD,Reeves RK,Smedley J,Keele BF,Burgener AD,Klatt NR
Sat Sep 01 00:00:00 UTC 2018
The Genetic Polymorphisms of NLRP3 Inflammasome Associated with T Helper Cells in Patients with Multiple Myeloma.
Journal of immunology research
Zhao X,Hua M,Yan S,Yu J,Han F,Zhong C,Wang R,Zhang C,Hou M,Ma D
12-7178 was used in Flow cytometry/Cell sorting to investigate the role of the NLRP3 inflammasome in multiple myeloma.
Fri Nov 09 00:00:00 UTC 2018
DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4+CD25high FOXP3+ Regulatory T Cells but Does Not Affect Their Suppressive Capacity.
Journal of immunology research
Landman S,Cruijsen M,Urbano PCM,Huls G,van Erp PEJ,van Rijssen E,Joosten I,Koenen HJPM
12-7178 was used in Flow cytometry/Cell sorting to examine the in vitro effect of derivative 5-aza-2'-deoxycytidine on the stability and function of FACS-sorted human naturally occurring CD4+CD25high FOXP3+ regulatory T cells.
Thu Oct 11 00:00:00 UTC 2018
The Effects of High Mobility Group Box-1 Protein on Peripheral Treg/Th17 Balance in Patients with Atherosclerosis.
Acta Cardiologica Sinica
Ding JW,Zhou T,Zheng XX,Wang XA,Tong XH,Luo CY,Zhang ZQ,Yu B
12-7178 was used in Flow cytometry/Cell sorting to explore the mechanism of regulatory T cell/Th17 imbalance and the role of high mobility group box-1 protein on the balance in atherosclerosis.
Sat Sep 01 00:00:00 UTC 2018
Th17 and IL-17 exhibit higher levels in osteonecrosis of the femoral head and have a positive correlation with severity of pain.
Endokrynologia Polska
Zou D,Zhang K,Yang Y,Ren Y,Zhang L,Xiao X,Zhang H,Liu S,Li J
12-7178-42 was used in Flow cytometry/Cell sorting to analyze the proinflammatory mediation expression of IL-17 and Th17, which perform key functions in regulating inflammatory processes in the inflamed synovium and peripheral blood in osteonecrosis of the femoral head.
Wed Oct 31 00:00:00 UTC 2018
Monomeric Immunoglobulin A from Plasma Inhibits Human Th17 Responses In Vitro Independent of FcαRI and DC-SIGN.
Frontiers in immunology
Saha C,Das M,Patil V,Stephen-Victor E,Sharma M,Wymann S,Jordi M,Vonarburg C,Kaveri SV,Bayry J
12-7178 was used in Flow cytometry/Cell sorting to suggest the potential therapeutic utility of monomeric IgA in autoimmune and inflammatory diseases that implicate Th17 cells.
Wed Nov 20 00:00:00 UTC 2019
Changes of Treg and Th17 cells as well as cytokines in children with acute bronchitis.
Experimental and therapeutic medicine
Tu Z,Xue H,Chen W,Cao L,Zhang W
12-7178-42 was used in Flow Cytometry to suggest that Treg and Th17 cells as well as their cytokines may be involved in the pathogenesis of acute bronchitis.
Sun Oct 01 00:00:00 UTC 2017
Application of a whole blood mycobacterial growth inhibition assay to study immunity against Mycobacterium tuberculosis in a high tuberculosis burden population.
PloS one
Baguma R,Penn-Nicholson A,Smit E,Erasmus M,Day J,Makhethe L,de Kock M,Hughes EJ,van Rooyen M,Pienaar B,Stone L,Hanekom W,Brennan MJ,Wallis RS,Hatherill M,Scriba TJ
Wed Oct 18 00:00:00 UTC 2017
Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue.
Scientific reports
Caër C,Rouault C,Le Roy T,Poitou C,Aron-Wisnewsky J,Torcivia A,Bichet JC,Clément K,Guerre-Millo M,André S
Published figure using IL-17A monoclonal antibody (Product # 12-7178-42) in Flow Cytometry
Wed Jun 07 00:00:00 UTC 2017
Suppressive IL-17A+Foxp3+ and ex-Th17 IL-17AnegFoxp3+ Treg cells are a source of tumour-associated Treg cells.
Nature communications
Downs-Canner S,Berkey S,Delgoffe GM,Edwards RP,Curiel T,Odunsi K,Bartlett DL,Obermajer N
12-7178 was used in Flow cytometry/Cell sorting to demonstrate the tumour-associated conversion of Th17 cells to Treg cells and identify transdifferentiation-associated markers.
Tue Mar 14 00:00:00 UTC 2017
Human Zika infection induces a reduction of IFN-γ producing CD4 T-cells and a parallel expansion of effector Vδ2 T-cells.
Scientific reports
Cimini E,Castilletti C,Sacchi A,Casetti R,Bordoni V,Romanelli A,Turchi F,Martini F,Tumino N,Nicastri E,Corpolongo A,Di Caro A,Kobinger G,Zumla A,Capobianchi MR,Ippolito G,Agrati C
12-7178 was used in Flow cytometry/Cell sorting to study the cellular immune response in the acute phase of human ZIKV infection and its role in protection and pathogenesis.
Mon Jul 24 00:00:00 UTC 2017
IL-1β, But Not Programed Death-1 and Programed Death Ligand Pathway, Is Critical for the Human Th17 Response to Mycobacterium tuberculosis.
Frontiers in immunology
Stephen-Victor E,Sharma VK,Das M,Karnam A,Saha C,Lecerf M,Galeotti C,Kaveri SV,Bayry J
12-7178 was used in Flow cytometry/Cell sorting to investigate the role of PD pathway in regulating Th17 response to M. tuberculosis, showing that IL-1β, but not that PD-1 pathway, is critical for response.
Wed Nov 20 00:00:00 UTC 2019
Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.
Transplantation
Hippen KL,Watkins B,Tkachev V,Lemire AM,Lehnen C,Riddle MJ,Singh K,Panoskaltsis-Mortari A,Vanhove B,Tolar J,Kean LS,Blazar BR
12-7178 was used in Flow cytometry/Cell sorting to develop a novel, optimised, nonhuman primate xenogenic graft-versus-host disease small animal model.
Thu Dec 01 00:00:00 UTC 2016
Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.
Transplantation
Hippen KL,Watkins B,Tkachev V,Lemire AM,Lehnen C,Riddle MJ,Singh K,Panoskaltsis-Mortari A,Vanhove B,Tolar J,Kean LS,Blazar BR
12-7178 was used in Flow cytometry/Cell sorting to develop a novel, optimised, nonhuman primate xenogenic graft-versus-host disease small animal model.
Thu Dec 01 00:00:00 UTC 2016
Altered expression of miR-92a correlates with Th17 cell frequency in patients with primary biliary cirrhosis.
International journal of molecular medicine
Liang DY,Hou YQ,Luo LJ,Ao L
12-7178 was used in Flow cytometry/Cell sorting to study the altered expression of miR-92a and its impact on the frequency of Th17 cells in patients with primary biliary cirrhosis.
Fri Jul 01 00:00:00 UTC 2016
Downregulation of RUNX3 moderates the frequency of Th17 and Th22 cells in patients with psoriasis.
Molecular medicine reports
Fu D,Song X,Hu H,Sun M,Li Z,Tian Z
12717842 was used in flow cytometry to define the underlying mechanism of Runt-related transcription factor 3's involvement in the differentiation of T-helper 17 and T-helper 22 cells in psoriasis
Wed Jun 01 00:00:00 UTC 2016
Effects of transcutaneous acupoint electrical stimulation on the imbalance of Th1, Th2, Th17 and Treg cells following thoracotomy of patients with lung cancer.
Experimental and therapeutic medicine
Wu H,Wang K,Li G,Meng D,Han J,Wang G,Li YU
12-7178 was used in Flow cytometry/Cell sorting to demonstrate that transcutaneous acupoint electrical stimulation was able to partially attenuate the postoperative immune depression of patients with lung cancer.
Mon Feb 01 00:00:00 UTC 2016
Equilibrium of Treg/Th17 cells of peripheral blood in syphilitic patients with sero-resistance.
Experimental and therapeutic medicine
Zhao J,Ma J,Zhang X,Li Q,Yang X
12-7178 was used in Flow cytometry/Cell sorting to examine the proportions of Treg and Th17 cells in the peripheral blood, and their expression of specific transcription factors, in sero-resistant syphilitic patients and healthy donors.
Wed Jun 01 00:00:00 UTC 2016
Characterization and Quantification of Innate Lymphoid Cell Subsets in Human Lung.
PloS one
De Grove KC,Provoost S,Verhamme FM,Bracke KR,Joos GF,Maes T,Brusselle GG
12-7178 was used in Flow cytometry/Cell sorting to study innate lymphoid cells in the human lung in healthy patients and those with chronic pulmonary disease.
Fri Jul 08 00:00:00 UTC 2016
Jejunal T Cell Inflammation in Human Obesity Correlates with Decreased Enterocyte Insulin Signaling.
Cell metabolism
Monteiro-Sepulveda M,Touch S,Mendes-Sá C,André S,Poitou C,Allatif O,Cotillard A,Fohrer-Ting H,Hubert EL,Remark R,Genser L,Tordjman J,Garbin K,Osinski C,Sautès-Fridman C,Leturque A,Clément K,Brot-Laroche E
12-7178 was used in Flow cytometry/Cell sorting to study inflammation of the absorptive small intestine in obese and diabetic patients.
Tue Jul 07 00:00:00 UTC 2015
CARD9-Dependent Neutrophil Recruitment Protects against Fungal Invasion of the Central Nervous System.
PLoS pathogens
Drummond RA,Collar AL,Swamydas M,Rodriguez CA,Lim JK,Mendez LM,Fink DL,Hsu AP,Zhai B,Karauzum H,Mikelis CM,Rose SR,Ferre EM,Yockey L,Lemberg K,Kuehn HS,Rosenzweig SD,Lin X,Chittiboina P,Datta SK,Belhorn TH,Weimer ET,Hernandez ML,Hohl TM,Kuhns DB,Lionakis MS
12-7178 was used in Flow cytometry/Cell sorting to highlight the role of CARD9-dependant neutrophil trafficking into the CNS and provide insight into the CNS fungal susceptibility of CARD9-deficient humans.
Tue Dec 01 00:00:00 UTC 2015
Breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems.
Science translational medicine
Ardeshir A,Narayan NR,Méndez-Lagares G,Lu D,Rauch M,Huang Y,Van Rompay KK,Lynch SV,Hartigan-O'Connor DJ
12-7178 was used in Flow cytometry/Cell sorting to investigate how diet might shape the primate immune system, showing that breast-fed and bottle-fed infant rhesus macaques develop distinct gut microbiotas and immune systems.
Wed Sep 03 00:00:00 UTC 2014
T cell-derived IL-22 amplifies IL-1β-driven inflammation in human adipose tissue: relevance to obesity and type 2 diabetes.
Diabetes
Dalmas E,Venteclef N,Caer C,Poitou C,Cremer I,Aron-Wisnewsky J,Lacroix-Desmazes S,Bayry J,Kaveri SV,Clément K,André S,Guerre-Millo M
12-7178 was used in Flow cytometry/Cell sorting to investigate the contribution of different cytokines to the proinflammatory signature of adipose tissue macrophages in type 2 diabetic obese patients.
Sun Jun 01 00:00:00 UTC 2014
CD4+ T cells contain early extrapulmonary tuberculosis (TB) dissemination and rapid TB progression and sustain multieffector functions of CD8+ T and CD3- lymphocytes: mechanisms of CD4+ T cell immunity.
Journal of immunology (Baltimore, Md. : 1950)
Yao S,Huang D,Chen CY,Halliday L,Wang RC,Chen ZW
12-7178 was used in Flow cytometry/Cell sorting to investigate the possibility that CD4(+) T cells can act as innate-like cells to contain very early Mycobacterium tuberculosis dissemination using CD4-depleted macaques.
Sat Mar 01 00:00:00 UTC 2014
Severe H7N9 infection is associated with decreased antigen-presenting capacity of CD14+ cells.
PloS one
Diao H,Cui G,Wei Y,Chen J,Zuo J,Cao H,Chen Y,Yao H,Tian Z,Li L
12-7178 was used in Flow cytometry/Cell sorting to investigate the characteristics of immune cells in patients with severe H7N9 infection.
Fri Nov 21 00:00:00 UTC 2014
Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection.
Blood
Cosgrove C,Ussher JE,Rauch A,Gärtner K,Kurioka A,Hühn MH,Adelmann K,Kang YH,Fergusson JR,Simmonds P,Goulder P,Hansen TH,Fox J,Günthard HF,Khanna N,Powrie F,Steel A,Gazzard B,Phillips RE,Frater J,Uhlig H,Klenerman P
12-7178 was used in Flow cytometry/Cell sorting to analyse the frequency and function of CD161++ /MAIT cells from patients at different stages of HIV infection.
Thu Feb 07 00:00:00 UTC 2013
Reconstitution of interleukin-17-producing T helper cells after allogeneic hematopoietic cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Bahr F,Wehner R,Platzbecker U,Wermke M,Shayegi N,Middeke JM,Röllig C,Schetelig J,Ehninger G,Schmitz M,Bornhäuser M,Tuve S
12-7178 was used in Flow cytometry/Cell sorting to conclude that quantitative reconstitution of Th1, Th1/17, and Th17 cells is impaired within 3 months of hematopoietic cell transplantation.
Fri Mar 01 00:00:00 UTC 2013
Intercellular adhesion molecule 1 mediates migration of Th1 and Th17 cells across human retinal vascular endothelium.
Investigative ophthalmology & visual science
Bharadwaj AS,Schewitz-Bowers LP,Wei L,Lee RW,Smith JR
12-7178 was used in Flow cytometry/Cell sorting to investigate the ability of human Th1- and Th17-polarised cells to cross a simulated human retinal endothelium, and examined the role of IgG superfamily members in this process.
Wed Oct 23 00:00:00 UTC 2013
CCL20 Secretion from the Nucleus Pulposus Improves the Recruitment of CCR6-Expressing Th17 Cells to Degenerated IVD Tissues.
PloS one
Zhang W,Nie L,Wang Y,Wang XP,Zhao H,Dongol S,Maharjan S,Cheng L
12-7178 was used in Flow cytometry/Cell sorting to understand the mechanisms by which IL-17 producing cells migrate into pathologic intervertebral disc tissues.
Fri Oct 13 00:00:00 UTC 2017
IL-17 and IFN-γ expression in lymphocytes from patients with active tuberculosis correlates with the severity of the disease.
Journal of leukocyte biology
Jurado JO,Pasquinelli V,Alvarez IB,Peña D,Rovetta AI,Tateosian NL,Romeo HE,Musella RM,Palmero D,Chuluyán HE,García VE
12-7178 was used in Flow cytometry/Cell sorting to investigate the induction and regulation of IFN-γ and IL-17 during active human Mycobacterium tuberculosis infection.
Fri Jun 01 00:00:00 UTC 2012
IL-2 simultaneously expands Foxp3+ T regulatory and T effector cells and confers resistance to severe tuberculosis (TB): implicative Treg-T effector cooperation in immunity to TB.
Journal of immunology (Baltimore, Md. : 1950)
Chen CY,Huang D,Yao S,Halliday L,Zeng G,Wang RC,Chen ZW
12-7178 was used in Flow cytometry/Cell sorting to show that IL-2 can activate and expand T effector cells and Foxp3(+) Treg populations while conferring resistance to severe TB.
Tue May 01 00:00:00 UTC 2012
Reduced frequency of memory T cells and increased Th17 responses in patients with active tuberculosis.
Clinical and vaccine immunology : CVI
Marín ND,París SC,Rojas M,García LF
12-7178 was used in Flow cytometry/Cell sorting to investigate the alterations in Mycobacterium tuberculosis T cell subsets in patients with active tuberculosis, showing reduced frequency of memory T cells and increased Th17 responses.
Mon Oct 01 00:00:00 UTC 2012
Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells.
Blood
Dusseaux M,Martin E,Serriari N,Péguillet I,Premel V,Louis D,Milder M,Le Bourhis L,Soudais C,Treiner E,Lantz O
12-7178 was used in Flow cytometry/Cell sorting to investigate the function of mucosal-associated invariant T cells.
Thu Jan 27 00:00:00 UTC 2011
Human slan (6-sulfo LacNAc) dendritic cells are inflammatory dermal dendritic cells in psoriasis and drive strong TH17/TH1 T-cell responses.
The Journal of allergy and clinical immunology
Hänsel A,Günther C,Ingwersen J,Starke J,Schmitz M,Bachmann M,Meurer M,Rieber EP,Schäkel K
12-7178 was used in an ELISA assay to define slanDCs as inflammatory dermal DCs in psoriasis and identify their strong capacity to induce TH17/TH1 responses.
Tue Mar 01 00:00:00 UTC 2011
T-cell immune function in tumor, skin, and peripheral blood of advanced stage melanoma patients: implications for immunotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research
Tjin EP,Konijnenberg D,Krebbers G,Mallo H,Drijfhout JW,Franken KL,van der Horst CM,Bos JD,Nieweg OE,Kroon BB,Haanen JB,Melief CJ,Vyth-Dreese FA,Luiten RM
12-7178-42 was used in immunohistochemistry (frozen) tissue to investigate T-cell effector function in relation to tumour-escape mechanisms.
Thu Sep 01 00:00:00 UTC 2011
Regulation of IL-17 in chronic inflammation in the human lung.
Clinical science (London, England : 1979)
Pridgeon C,Bugeon L,Donnelly L,Straschil U,Tudhope SJ,Fenwick P,Lamb JR,Barnes PJ,Dallman MJ
12-7178 was used in Flow cytometry/Cell sorting to suggest that IL-17-expressing cells are present in chronically inflamed lung tissue.
Wed Jun 01 00:00:00 UTC 2011
Strong viremia control in vaccinated macaques does not prevent gradual Th17 cell loss from central memory.
Vaccine
Demberg T,Ettinger AC,Aladi S,McKinnon K,Kuddo T,Venzon D,Patterson LJ,Phillips TM,Robert-Guroff M
12-7178 was used in Flow cytometry/Cell sorting to investigate a vaccine regimen that potently reduced viremia post-challenge preserved Th17 and Tc17 cells, thus benefiting in the absence of sterilizing protection.
Thu Aug 11 00:00:00 UTC 2011
Identification of Mycobacterium tuberculosis-specific Th1, Th17 and Th22 cells using the expression of CD40L in tuberculous pleurisy.
PloS one
Li L,Qiao D,Fu X,Lao S,Zhang X,Wu C
12-7178-42 was used in Flow Cytometry to identify CD40L expression on Mycobacterium tuberculosis-specific CD4 T cells as a marker for the evaluation and isolation of these cells.
Mon Oct 17 00:00:00 UTC 2011
Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns.
American journal of respiratory and critical care medicine
Kagina BM,Abel B,Scriba TJ,Hughes EJ,Keyser A,Soares A,Gamieldien H,Sidibana M,Hatherill M,Gelderbloem S,Mahomed H,Hawkridge A,Hussey G,Kaplan G,Hanekom WA
12-7178 was used in Flow cytometry/Cell sorting to test protection against childhood TB disease after newborn vaccination with bacillus Calmette-Guérin (BCG).
Fri Oct 15 00:00:00 UTC 2010
Mechanisms underlying γδ T-cell subset perturbations in SIV-infected Asian rhesus macaques.
Blood
Harris LD,Klatt NR,Vinton C,Briant JA,Tabb B,Ladell K,Lifson J,Estes JD,Price DA,Hirsch VM,Brenchley JM
12-7178 was used in Flow cytometry/Cell sorting to study differing subsets of γδ T cells in HIV and Simian immunodeficiency virus-infected individuals.
Thu Nov 18 00:00:00 UTC 2010
In colorectal cancer mast cells contribute to systemic regulatory T-cell dysfunction.
Proceedings of the National Academy of Sciences of the United States of America
Blatner NR,Bonertz A,Beckhove P,Cheon EC,Krantz SB,Strouch M,Weitz J,Koch M,Halverson AL,Bentrem DJ,Khazaie K
12-7178 was used in Flow cytometry/Cell sorting to identify that mast cells induce Treg to switch function and escalate inflammation in CRC without losing T-cell-suppressive properties.
Tue Apr 06 00:00:00 UTC 2010
Compromised gastrointestinal integrity in pigtail macaques is associated with increased microbial translocation, immune activation, and IL-17 production in the absence of SIV infection.
Mucosal immunology
Klatt NR,Harris LD,Vinton CL,Sung H,Briant JA,Tabb B,Morcock D,McGinty JW,Lifson JD,Lafont BA,Martin MA,Levine AD,Estes JD,Brenchley JM
12-7178 was used in Flow cytometry/Cell sorting to assess whether high basal levels of immune activation and microbial translocation exist in pigtail macaques.
Thu Jul 01 00:00:00 UTC 2010
Differentiation, distribution and gammadelta T cell-driven regulation of IL-22-producing T cells in tuberculosis.
PLoS pathogens
Yao S,Huang D,Chen CY,Halliday L,Zeng G,Wang RC,Chen ZW
12-7178 was used in Flow cytometry/Cell sorting to investigate differentiation, distribution and immune regulation of human IL-22-producing T cells in infections.
Fri Feb 26 00:00:00 UTC 2010
Differentiation, distribution and gammadelta T cell-driven regulation of IL-22-producing T cells in tuberculosis.
PLoS pathogens
Yao S,Huang D,Chen CY,Halliday L,Zeng G,Wang RC,Chen ZW
12-7178 was used in Flow cytometry/Cell sorting to investigate differentiation, distribution and immune regulation of human IL-22-producing T cells in infections.
Fri Feb 26 00:00:00 UTC 2010
Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ness-Schwickerath KJ,Jin C,Morita CT
12-7178 was used in Flow cytometry/Cell sorting to determine if primate and murine gammadelta T cells play similar roles in being major sources of IL-17A in antimicrobial and autoimmune responses.
Tue Jun 15 00:00:00 UTC 2010
Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ness-Schwickerath KJ,Jin C,Morita CT
12-7178 was used in Flow cytometry/Cell sorting to determine if primate and murine gammadelta T cells play similar roles in being major sources of IL-17A in antimicrobial and autoimmune responses.
Tue Jun 15 00:00:00 UTC 2010
Intensive chemotherapy for acute myeloid leukemia differentially affects circulating TC1, TH1, TH17 and TREG cells.
BMC immunology
Ersvaer E,Liseth K,Skavland J,Gjertsen BT,Bruserud Ø
12-7178 was used in Flow cytometry/Cell sorting to investigate the frequencies of various T cell subsets (TC1, TH1, TH17) and CD25+ FoxP3+ TREG cells in acute myeloid leukemia patients, with untreated disease and following intensive chemotherapy.
Fri Jul 09 00:00:00 UTC 2010
Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients.
The Journal of investigative dermatology
van den Boorn JG,Konijnenberg D,Dellemijn TA,van der Veen JP,Bos JD,Melief CJ,Vyth-Dreese FA,Luiten RM
12-7178 was used in Flow cytometry/Cell sorting to show that perilesional cytotoxic T cells eradicate pigment cells, the characteristic hallmark of vitiligo.
Tue Sep 01 00:00:00 UTC 2009
1,25-Dihydroxyvitamin D3 and IL-2 combine to inhibit T cell production of inflammatory cytokines and promote development of regulatory T cells expressing CTLA-4 and FoxP3.
Journal of immunology (Baltimore, Md. : 1950)
Jeffery LE,Burke F,Mura M,Zheng Y,Qureshi OS,Hewison M,Walker LS,Lammas DA,Raza K,Sansom DM
12-7178 was used in Flow cytometry/Cell sorting to assess the effects of the active form of vitamin D, 1,25-dihydroxyvitamin D(3) on human CD4(+)CD25(-) T cells.
Sun Nov 01 00:00:00 UTC 2009
A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society
Kap YS,van Meurs M,van Driel N,Koopman G,Melief MJ,Brok HP,Laman JD,'t Hart BA
Tue Dec 01 00:00:00 UTC 2009
